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Poole, Leslie

One or more keywords matched the following items that are connected to Poole, Leslie

Item Type	Name
Academic Article	Identification of cysteine sulfenic acid in AhpC of alkyl hydroperoxide reductase.
Academic Article	Human mitochondrial branched chain aminotransferase: structural basis for substrate specificity and role of redox active cysteines.
Academic Article	Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling.
Academic Article	Isotope-coded, iodoacetamide-based reagent to determine individual cysteine pK(a) values by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Academic Article	Discovering mechanisms of signaling-mediated cysteine oxidation.
Academic Article	Conformational and oligomeric effects on the cysteine pK(a) of tryparedoxin peroxidase.
Academic Article	Cysteine-based redox switches in enzymes.
Academic Article	Structure-based insights into the catalytic power and conformational dexterity of peroxiredoxins.
Academic Article	Dimers to doughnuts: redox-sensitive oligomerization of 2-cysteine peroxiredoxins.
Academic Article	Catalytic mechanism of thiol peroxidase from Escherichia coli. Sulfenic acid formation and overoxidation of essential CYS61.
Academic Article	Roles for cysteine residues in the regulatory CXXC motif of human mitochondrial branched chain aminotransferase enzyme.
Academic Article	Bacterial defenses against oxidants: mechanistic features of cysteine-based peroxidases and their flavoprotein reductases.
Academic Article	Structural basis for the retroreduction of inactivated peroxiredoxins by human sulfiredoxin.
Academic Article	Oxidized and synchrotron cleaved structures of the disulfide redox center in the N-terminal domain of Salmonella typhimurium AhpF.
Academic Article	Novel organic hydroperoxide-sensing and responding mechanisms for OhrR, a major bacterial sensor and regulator of organic hydroperoxide stress.
Academic Article	Cysteine reactivity and thiol-disulfide interchange pathways in AhpF and AhpC of the bacterial alkyl hydroperoxide reductase system.
Academic Article	The requirement of reversible cysteine sulfenic acid formation for T cell activation and function.
Academic Article	Fluorescent and affinity-based tools to detect cysteine sulfenic acid formation in proteins.
Academic Article	The catalytic mechanism of peroxiredoxins.
Academic Article	Mutant AhpC peroxiredoxins suppress thiol-disulfide redox deficiencies and acquire deglutathionylating activity.
Academic Article	Functional site profiling and electrostatic analysis of cysteines modifiable to cysteine sulfenic acid.
Academic Article	Cysteine pK(a) values for the bacterial peroxiredoxin AhpC.
Academic Article	Typical 2-Cys peroxiredoxins--structures, mechanisms and functions.
Academic Article	Water-soluble triarylphosphines as biomarkers for protein S-nitrosation.
Academic Article	Localized cysteine sulfenic acid formation by vascular endothelial growth factor: role in endothelial cell migration and angiogenesis.
Academic Article	A simple and effective strategy for labeling cysteine sulfenic acid in proteins by utilization of ß-ketoesters as cleavable probes.
Academic Article	The reversible formation of cysteine sulfenic acid promotes B-cell activation and proliferation.
Academic Article	Electrostatics of cysteine residues in proteins: parameterization and validation of a simple model.
Academic Article	Essential thioredoxin-dependent peroxiredoxin system from Helicobacter pylori: genetic and kinetic characterization.
Concept	Cysteine
Academic Article	Thiol-blocking electrophiles interfere with labeling and detection of protein sulfenic acids.
Academic Article	The sensitive balance between the fully folded and locally unfolded conformations of a model peroxiredoxin.
Academic Article	Chemical approaches to detect and analyze protein sulfenic acids.
Academic Article	Endosomal H2O2 production leads to localized cysteine sulfenic acid formation on proteins during lysophosphatidic acid-mediated cell signaling.
Academic Article	Strained cycloalkynes as new protein sulfenic acid traps.
Academic Article	Tuning of peroxiredoxin catalysis for various physiological roles.
Academic Article	Introduction: What we do and do not know regarding redox processes of thiols in signaling pathways.
Academic Article	The basics of thiols and cysteines in redox biology and chemistry.
Academic Article	Cysteine-Mediated Redox Regulation of Cell Signaling in Chondrocytes Stimulated With Fibronectin Fragments.
Grant	New Reagents for Tracking Protein Oxidation in Cells by MS and Imaging Methods
Grant	2012 Thiol-based Redox Regulation &Signaling GRC and GRS
Grant	Proteomic Profiling of Cancer-Related Redox Signaling Pathways
Grant	Profiling of Redox-Sensitive Signaling Proteins
Grant	Mechanisms and Regulation of Peroxiredoxins
Academic Article	The SAMHD1 dNTP Triphosphohydrolase Is Controlled by a Redox Switch.
Academic Article	Experimentally Dissecting the Origins of Peroxiredoxin Catalysis.
Academic Article	The Oxidative State of Cysteine Thiol 144 Regulates the SIRT6 Glucose Homeostat.
Academic Article	Endogenous, regulatory cysteine sulfenylation of ERK kinases in response to proliferative signals.
Academic Article	SVM-SulfoSite: A support vector machine based predictor for sulfenylation sites.
Academic Article	Novel hyperoxidation resistance motifs in 2-Cys peroxiredoxins.
Academic Article	Differential Kinetics of Two-Cysteine Peroxiredoxin Disulfide Formation Reveal a Novel Model for Peroxide Sensing.
Academic Article	Chaperone activation and client binding of a 2-cysteine peroxiredoxin.
Academic Article	H2O2 oxidation of cysteine residues in c-Jun N-terminal kinase 2 (JNK2) contributes to redox regulation in human articular chondrocytes.
Academic Article	Unraveling the effects of peroxiredoxin 2 nitration; role of C-terminal tyrosine 193.
Grant	Redox Regulation of Cysteine-Dependent Peroxidases and Signal Transduction Pathways
Academic Article	Introduction to approaches and tools for the evaluation of protein cysteine oxidation.
Academic Article	Cysteine oxidation of copper transporter CTR1 drives VEGFR2 signalling and angiogenesis.

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Cysteine