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Parks, John
One or more keywords matched the following items that are connected to Parks, John
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Academic Article Alteration of plasma HDL cholesteryl ester composition with transgenic expression of a point mutation (E149A) of human LCAT.
Academic Article Lecithin:cholesterol acyltransferase deficiency increases atherosclerosis in the low density lipoprotein receptor and apolipoprotein E knockout mice.
Academic Article Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice.
Academic Article Plasma cholesteryl esters provided by lecithin:cholesterol acyltransferase and acyl-coenzyme a:cholesterol acyltransferase 2 have opposite atherosclerotic potential.
Academic Article ACAT2 contributes cholesteryl esters to newly secreted VLDL, whereas LCAT adds cholesteryl ester to LDL in mice.
Academic Article Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I.
Academic Article HDLs in apoA-I transgenic Abca1 knockout mice are remodeled normally in plasma but are hypercatabolized by the kidney.
Academic Article Intestinal ABCA1 directly contributes to HDL biogenesis in vivo.
Academic Article Reduction in ABCG1 in Type 2 diabetic mice increases macrophage foam cell formation.
Academic Article Tissue-specific induction of intestinal ABCA1 expression with a liver X receptor agonist raises plasma HDL cholesterol levels.
Academic Article Beta-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment.
Academic Article LXR signaling couples sterol metabolism to proliferation in the acquired immune response.
Academic Article Specific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function.
Academic Article Combined therapy of dietary fish oil and stearoyl-CoA desaturase 1 inhibition prevents the metabolic syndrome and atherosclerosis.
Academic Article Alternative splicing attenuates transgenic expression directed by the apolipoprotein E promoter-enhancer based expression vector pLIV11.
Academic Article Targeted deletion of hepatocyte ABCA1 leads to very low density lipoprotein triglyceride overproduction and low density lipoprotein hypercatabolism.
Academic Article Myeloid differentiation primary response protein 88 couples reverse cholesterol transport to inflammation.
Academic Article Adipose tissue ATP binding cassette transporter A1 contributes to high-density lipoprotein biogenesis in vivo.
Academic Article Hepatic ABCA1 and VLDL triglyceride production.
Academic Article Macrophage 12/15 lipoxygenase expression increases plasma and hepatic lipid levels and exacerbates atherosclerosis.
Academic Article Omega-3 fatty acids ameliorate atherosclerosis by favorably altering monocyte subsets and limiting monocyte recruitment to aortic lesions.
Academic Article An ACACB variant implicated in diabetic nephropathy associates with body mass index and gene expression in obese subjects.
Academic Article Effect of apolipoprotein A-I deficiency on lecithin:cholesterol acyltransferase activation in mouse plasma.
Academic Article In vivo contribution of LCAT to apolipoprotein B lipoprotein cholesteryl esters in LDL receptor and apolipoprotein E knockout mice.
Academic Article Transgenic overexpression of human lecithin: cholesterol acyltransferase (LCAT) in mice does not increase aortic cholesterol deposition.
Academic Article Enhancement of scavenger receptor class B type I-mediated selective cholesteryl ester uptake from apoA-I(-/-) high density lipoprotein (HDL) by apolipoprotein A-I requires HDL reorganization by lecithin cholesterol acyltransferase.
Academic Article Harmful effects of increased LDLR expression in mice with human APOE*4 but not APOE*3.
Academic Article Compared with Acyl-CoA:cholesterol O-acyltransferase (ACAT) 1 and lecithin:cholesterol acyltransferase, ACAT2 displays the greatest capacity to differentiate cholesterol from sitosterol.
Academic Article Prebeta high density lipoprotein has two metabolic fates in human apolipoprotein A-I transgenic mice.
Academic Article Apolipoprotein E is the major physiological activator of lecithin-cholesterol acyltransferase (LCAT) on apolipoprotein B lipoproteins.
Academic Article Hepatic ATP-binding cassette transporter A1 is a key molecule in high-density lipoprotein cholesteryl ester metabolism in mice.
Academic Article Both hepatic and extrahepatic ABCA1 have discrete and essential functions in the maintenance of plasma high-density lipoprotein cholesterol levels in vivo.
Academic Article Functional LCAT deficiency in human apolipoprotein A-I transgenic, SR-BI knockout mice.
Academic Article Echium oil reduces plasma lipids and hepatic lipogenic gene expression in apoB100-only LDL receptor knockout mice.
Academic Article Increased cellular free cholesterol in macrophage-specific Abca1 knock-out mice enhances pro-inflammatory response of macrophages.
Academic Article Initial interaction of apoA-I with ABCA1 impacts in vivo metabolic fate of nascent HDL.
Academic Article Inhibition of stearoyl-coenzyme A desaturase 1 dissociates insulin resistance and obesity from atherosclerosis.
Academic Article LCAT synthesized by primary astrocytes esterifies cholesterol on glia-derived lipoproteins.
Academic Article Tissue-specific roles of ABCA1 influence susceptibility to atherosclerosis.
Academic Article Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR.
Academic Article An innate immunity signaling process suppresses macrophage ABCA1 expression through IRAK-1-mediated downregulation of retinoic acid receptor alpha and NFATc2.
Academic Article ATP-binding cassette transporter G1 negatively regulates thymocyte and peripheral lymphocyte proliferation.
Academic Article ABCG1 deficiency in mice promotes endothelial activation and monocyte-endothelial interactions.
Academic Article An intracellular role for ABCG1-mediated cholesterol transport in the regulated secretory pathway of mouse pancreatic beta cells.
Academic Article Macrophage ABCA1 reduces MyD88-dependent Toll-like receptor trafficking to lipid rafts by reduction of lipid raft cholesterol.
Academic Article Echium oil reduces atherosclerosis in apoB100-only LDLrKO mice.
Academic Article CGI-58/ABHD5-derived signaling lipids regulate systemic inflammation and insulin action.
Academic Article The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence.
Academic Article Myeloid cell-specific ABCA1 deletion protects mice from bacterial infection.
Academic Article ATP-binding cassette transporter G1 intrinsically regulates invariant NKT cell development.
Academic Article Impaired cholesterol efflux in senescent macrophages promotes age-related macular degeneration.
Concept Mice, Knockout
Concept Mice
Concept Mice, Inbred C57BL
Concept Mice, Transgenic
Concept Mice, Inbred BALB C
Concept Mice, Obese
Concept Mice, Nude
Concept Mice, Inbred DBA
Concept Mice, Mutant Strains
Academic Article Deficiency of ATP-binding cassette transporters A1 and G1 in macrophages increases inflammation and accelerates atherosclerosis in mice.
Academic Article Increased cholesterol content in gammadelta (?d) T lymphocytes differentially regulates their activation.
Academic Article Echium oil reduces plasma triglycerides by increasing intravascular lipolysis in apoB100-only low density lipoprotein (LDL) receptor knockout mice.
Academic Article Liver ABCA1 deletion in LDLrKO mice does not impair macrophage reverse cholesterol transport or exacerbate atherogenesis.
Academic Article Myeloid cell-specific ABCA1 deletion does not worsen insulin resistance in HF diet-induced or genetically obese mouse models.
Academic Article Lipid absorption defects in intestine-specific microsomal triglyceride transfer protein and ATP-binding cassette transporter A1-deficient mice.
Academic Article Hepatic apolipoprotein M (apoM) overexpression stimulates formation of larger apoM/sphingosine 1-phosphate-enriched plasma high density lipoprotein.
Academic Article Myeloid cell-specific ATP-binding cassette transporter A1 deletion has minimal impact on atherogenesis in atherogenic diet-fed low-density lipoprotein receptor knockout mice.
Academic Article Histone deacetylase 9 represses cholesterol efflux and alternatively activated macrophages in atherosclerosis development.
Academic Article Inhibiting DNA Methylation by 5-Aza-2'-deoxycytidine ameliorates atherosclerosis through suppressing macrophage inflammation.
Academic Article Uncleaved ApoM signal peptide is required for formation of large ApoM/sphingosine 1-phosphate (S1P)-enriched HDL particles.
Academic Article Botanical oils enriched in n-6 and n-3 FADS2 products are equally effective in preventing atherosclerosis and fatty liver.
Academic Article Proteomic Analysis of ABCA1-Null Macrophages Reveals a Role for Stomatin-Like Protein-2 in Raft Composition and Toll-Like Receptor Signaling.
Academic Article Biogenesis and cytotoxicity of APOL1 renal risk variant proteins in hepatocytes and hepatoma cells.
Academic Article LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling.
Academic Article A Systematic Investigation of Structure/Function Requirements for the Apolipoprotein A-I/Lecithin Cholesterol Acyltransferase Interaction Loop of High-density Lipoprotein.
Academic Article Myeloid Deletion of a1AMPK Exacerbates Atherosclerosis in LDL Receptor Knockout (LDLRKO) Mice.
Academic Article Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Endothelial Cells Accelerates Atherosclerosis in Mice.
Academic Article MicroRNA-33 Regulates the Innate Immune Response via ATP Binding Cassette Transporter-mediated Remodeling of Membrane Microdomains.
Academic Article Very Low Density Lipoprotein Assembly Is Required for cAMP-responsive Element-binding Protein H Processing and Hepatic Apolipoprotein A-IV Expression.
Academic Article In vivo activation of leukocyte GPR120/FFAR4 by PUFAs has minimal impact on atherosclerosis in LDL receptor knockout mice.
Academic Article Quercetin, a functional compound of onion peel, remodels white adipocytes to brown-like adipocytes.
Grant Regulation of ApoB Lipoprotein Expansion and Hepatic Lipid Efflux by ApoA-IV
Grant Hepatocyte Abca1, cholesterol trafficking, and lipid mobilization
Grant Macrophage, ABCA1, Inflammation, and Atherosclerosis
Grant LCAT, Lipids, and Atherosclerosis
Academic Article Hepatocyte ABCA1 Deletion Impairs Liver Insulin Signaling and Lipogenesis.
Academic Article Hepatic ABCA1 deficiency is associated with delayed apolipoprotein B secretory trafficking and augmented VLDL triglyceride secretion.
Academic Article Slfn2 mutation-induced loss of T-cell quiescence leads to elevated de novo sterol synthesis.
Academic Article ?-5 Fatty Acid Desaturase FADS1 Impacts Metabolic Disease by Balancing Proinflammatory and Proresolving Lipid Mediators.
Academic Article LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis.
Academic Article Targeted Deletion of Adipocyte Abca1 (ATP-Binding Cassette Transporter A1) Impairs Diet-Induced Obesity.
Academic Article Tpcn2 knockout mice have improved insulin sensitivity and are protected against high-fat diet-induced weight gain.
Academic Article Feeding of tobacco blend or nicotine induced weight loss associated with decreased adipocyte size and increased physical activity in male mice.
Academic Article Targeted Deletion of Hepatocyte Abca1 Increases Plasma HDL (High-Density Lipoprotein) Reverse Cholesterol Transport via the LDL (Low-Density Lipoprotein) Receptor.
Academic Article Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis.
Academic Article Effect of quercetin on nonshivering thermogenesis of brown adipose tissue in high-fat diet-induced obese mice.
Academic Article Hematopoietic Cell-Specific SLC37A2 Deficiency Accelerates Atherosclerosis in LDL Receptor-Deficient Mice.
Academic Article Apolipoprotein M and Sphingosine-1-Phosphate Receptor 1 Promote the Transendothelial Transport of High-Density Lipoprotein.
Academic Article The effects of brewers' spent grain on high-fat diet-induced fatty liver.
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