| Item Type | Name |
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Academic Article
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Induction of stable prenatal tolerance to beta-galactosidase by in utero gene transfer into preimmune sheep fetuses.
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Academic Article
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Adult stem cell plasticity and methods of detection.
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Academic Article
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Ex vivo expanded cord blood cells provide rapid engraftment in fetal sheep but lack long-term engrafting potential.
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Academic Article
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Reversible expression of CD34 by adult human bone marrow long-term engrafting hematopoietic stem cells.
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Academic Article
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The sheep model of in utero gene therapy.
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Academic Article
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A large animal noninjury model for study of human stem cell plasticity.
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Academic Article
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Reduced stem cell factor links smooth myopathy and loss of interstitial cells of cajal in murine diabetic gastroparesis.
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Academic Article
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The human-sheep chimeras as a model for human stem cell mobilization and evaluation of hematopoietic grafts' potential.
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Academic Article
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Early fetal gene delivery utilizes both central and peripheral mechanisms of tolerance induction.
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Academic Article
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Factors determining the risk of inadvertent retroviral transduction of male germ cells after in utero gene transfer in sheep.
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Academic Article
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Generation of tissue-specific cells from MSC does not require fusion or donor-to-host mitochondrial/membrane transfer.
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Academic Article
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In vivo generation of beta-cell-like cells from CD34(+) cells differentiated from human embryonic stem cells.
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Academic Article
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Phenotypic correction of hemophilia A in sheep by postnatal intraperitoneal transplantation of FVIII-expressing MSC.
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Academic Article
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Expression levels of the PiT-2 receptor explain, in part, the gestational age-dependent alterations in transduction efficiency after in utero retroviral-mediated gene transfer.
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Academic Article
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Development and characterization of recombinant ovine coagulation factor VIII.
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Academic Article
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Detection of human cells in human/sheep chimeric lambs with in vitro human stroma-forming potential.
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Academic Article
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Cytomegalovirus as a cause of pancytopenia.
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Academic Article
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The human/sheep xenograft model: a large animal model of human hematopoiesis.
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Academic Article
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Transplantation of hematopoietic stem cells in utero.
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Academic Article
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Human bone marrow CD34- cells engraft in vivo and undergo multilineage expression that includes giving rise to CD34+ cells.
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Academic Article
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Engraftment and multilineage expression of human bone marrow CD34- cells in vivo.
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Academic Article
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In utero transfer and expression of exogenous genes in sheep.
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Academic Article
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Evaluation of serum-free culture conditions able to support the ex vivo expansion and engraftment of human hematopoietic stem cells in the human-to-sheep xenograft model.
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Academic Article
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Umbilical cord blood cells capable of engrafting in primary, secondary, and tertiary xenogeneic hosts are preserved after ex vivo culture in a noncontact system.
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Academic Article
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The monoclonal antibody W7C5 defines a novel surface antigen on hematopoietic stem cells.
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Academic Article
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Human natural killer cell development in a xenogeneic culture system.
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Academic Article
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Differentiative potential of human metanephric mesenchymal cells.
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Academic Article
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Purification of interstitial cells of Cajal by fluorescence-activated cell sorting.
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Academic Article
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Human haematopoietic stem cells that mediate long-term in vivo engraftment are not susceptible to infection by human cytomegalovirus.
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Academic Article
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Plasticity of human stem cells in the fetal sheep model of human stem cell transplantation.
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Academic Article
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Human mesenchymal stem cells form Purkinje fibers in fetal sheep heart.
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Academic Article
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Formation of human hepatocytes by human hematopoietic stem cells in sheep.
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Academic Article
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The fetal sheep: a unique model system for assessing the full differentiative potential of human stem cells.
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Academic Article
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A new human somatic stem cell from placental cord blood with intrinsic pluripotent differentiation potential.
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Academic Article
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Gestational age of recipient determines pattern and level of transgene expression following in utero retroviral gene transfer.
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Academic Article
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In vivo haematopoietic potential of human neural stem cells.
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Academic Article
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Male germ-line cells are at risk following direct-injection retroviral-mediated gene transfer in utero.
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Academic Article
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The time course of engraftment of human mesenchymal stem cells in fetal heart demonstrates that Purkinje fiber aggregates derive from a single cell and not multi-cell homing.
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Academic Article
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Efficient generation of human hepatocytes by the intrahepatic delivery of clonal human mesenchymal stem cells in fetal sheep.
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Academic Article
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The correlation between the adsorption of adhesive proteins and cell behaviour on hydroxyl-methyl mixed self-assembled monolayers.
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Academic Article
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Development and characterization of a novel CD34 monoclonal antibody that identifies sheep hematopoietic stem/progenitor cells.
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Academic Article
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Induction of notch signaling by immobilization of jagged-1 on self-assembled monolayers.
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Academic Article
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Clinical and molecular characterization of a re-established line of sheep exhibiting hemophilia A.
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Academic Article
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Persistent circulating human insulin in sheep transplanted in utero with human mesenchymal stem cells.
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Academic Article
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Characterization and functionality of cardiac progenitor cells in congenital heart patients.
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Academic Article
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Distinct contribution of human cord blood-derived endothelial colony forming cells to liver and gut in a fetal sheep model.
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Academic Article
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Modulation of human mesenchymal stem cell immunogenicity through forced expression of human cytomegalovirus us proteins.
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Academic Article
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Retention and multilineage expression of human hematopoietic stem cells in human-sheep chimeras.
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Academic Article
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The role of sheep stroma in human haemopoiesis in the human/sheep chimaeras.
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Academic Article
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Sustained, retransplantable, multilineage engraftment of highly purified adult human bone marrow stem cells in vivo.
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Academic Article
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AC133, a novel marker for human hematopoietic stem and progenitor cells.
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Academic Article
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Engraftment of cultured human hematopoietic cells in sheep.
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Academic Article
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Plasmodium-falciparum-infected erythrocytes adhere to immortalized human bone marrow endothelial cells.
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Academic Article
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Homing of human cells in the fetal sheep model: modulation by antibodies activating or inhibiting very late activation antigen-4-dependent function.
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Academic Article
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Cotransplantation of stroma results in enhancement of engraftment and early expression of donor hematopoietic stem cells in utero.
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Academic Article
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Cotransplantation of human stromal cell progenitors into preimmune fetal sheep results in early appearance of human donor cells in circulation and boosts cell levels in bone marrow at later time points after transplantation.
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Academic Article
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Kinetics of engraftment of CD34(-) and CD34(+) cells from mobilized blood differs from that of CD34(-) and CD34(+) cells from bone marrow.
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Concept
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Models, Animal
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Concept
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Animals
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Concept
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Animals, Genetically Modified
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Concept
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Disease Models, Animal
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Concept
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Animals, Newborn
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Academic Article
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EphB2 isolates a human marrow stromal cell subpopulation with enhanced ability to contribute to the resident intestinal cellular pool.
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Academic Article
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Regenerative medicine: prospects for the treatment of inflammatory bowel disease.
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Academic Article
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Characterization of naturally-occurring humoral immunity to AAV in sheep.
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Academic Article
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Temporal definition of haematopoietic stem cell niches in a large animal model of in utero stem cell transplantation.
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Academic Article
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Sheep CD34+ amniotic fluid cells have hematopoietic potential and engraft after autologous in utero transplantation.
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Academic Article
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The hematopoietic system in the context of regenerative medicine.
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Academic Article
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Boosting Hematopoietic Engraftment after in Utero Transplantation through Vascular Niche Manipulation.
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Academic Article
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In vitro and in vivo assessment of direct effects of simulated solar and galactic cosmic radiation on human hematopoietic stem/progenitor cells.
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Grant
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Postnatal Cell-Based Therapies for Hemophilia A
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Grant
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In Utero Stem Cell Transplantation for Hemophilia A
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Grant
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Functional Analysis of the Hematopoietic Niche during Ontogeny
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Grant
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Prenatal Cell and Gene Therapy for Hemophilia A
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Academic Article
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Indocyanine green loaded hyaluronan-derived nanoparticles for fluorescence-enhanced surgical imaging of pancreatic cancer.
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Academic Article
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Evaluating Interaction of Cord Blood Hematopoietic Stem/Progenitor Cells with Functionally Integrated Three-Dimensional Microenvironments.
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Grant
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cGMP Manufacture Of FVIII-Expressing Placental Cells For Hemophilia A
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Academic Article
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In Utero Gene Therapy Consensus Statement from the IFeTIS.
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Academic Article
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Transplanting FVIII/ET3-secreting cells in fetal sheep increases FVIII levels long-term without inducing immunity or toxicity.
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Academic Article
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Autologous bone marrow-derived MSCs engineered to express oFVIII-FLAG engraft in adult sheep and produce an effective increase in plasma FVIII levels.
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Academic Article
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Organoids and microphysiological systems: Promising models for accelerating AAV gene therapy studies.
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Academic Article
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Gene and Stem Cell Therapies for Fetal Care: A Review.
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Academic Article
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Mesenchymal Stromal Cell Secretome: Influencing Therapeutic Potential by Cellular Pre-conditioning.
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Academic Article
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Bone marrow cell response after injury and during early stage of regeneration is independent of the tissue-of-injury in 2 injury models.
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Academic Article
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New models to investigate mechanisms of disease genesis from primitive BCR-ABL(+) hematopoietic cells.
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Academic Article
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KDR receptor: a key marker defining hematopoietic stem cells.
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