| Item Type | Name |
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Academic Article
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The roles of coenzyme A in the pyruvate:ferredoxin oxidoreductase reaction mechanism: rate enhancement of electron transfer from a radical intermediate to an iron-sulfur cluster.
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Academic Article
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A reciprocal single mutation affects the metal requirement of 3-deoxy-D-manno-2-octulosonate-8-phosphate (KDO8P) synthases from Aquifex pyrophilus and Escherichia coli.
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Academic Article
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Probing the role of tightly bound phosphoenolpyruvate in Escherichia coli 3-deoxy-d-manno-octulosonate 8-phosphate synthase catalysis using quantitative time-resolved electrospray ionization mass spectrometry in the millisecond time range.
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Academic Article
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The precise sequence of FGF receptor autophosphorylation is kinetically driven and is disrupted by oncogenic mutations.
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Academic Article
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Crystal structure and catalytic properties of Bacillus anthracis CoADR-RHD: implications for flavin-linked sulfur trafficking.
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Academic Article
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Use of dimedone-based chemical probes for sulfenic acid detection evaluation of conditions affecting probe incorporation into redox-sensitive proteins.
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Academic Article
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A coevolutionary residue network at the site of a functionally important conformational change in a phosphohexomutase enzyme family.
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Academic Article
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Insights into the mechanism of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (Phe) from Escherichia coli using a transient kinetic analysis.
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Academic Article
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The use of (E)- and (Z)-phosphoenol-3-fluoropyruvate as mechanistic probes reveals significant differences between the active sites of KDO8P and DAHP synthases.
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Academic Article
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Autophosphorylation of FGFR1 kinase is mediated by a sequential and precisely ordered reaction.
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Academic Article
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EPR spectroscopic and computational characterization of the hydroxyethylidene-thiamine pyrophosphate radical intermediate of pyruvate:ferredoxin oxidoreductase.
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Academic Article
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Fluorescent and affinity-based tools to detect cysteine sulfenic acid formation in proteins.
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Academic Article
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Identification of intact protein thiosulfinate intermediate in the reduction of cysteine sulfinic acid in peroxiredoxin by human sulfiredoxin.
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Academic Article
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Backbone flexibility, conformational change, and catalysis in a phosphohexomutase from Pseudomonas aeruginosa.
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Academic Article
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Water-soluble triarylphosphines as biomarkers for protein S-nitrosation.
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Academic Article
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Breaking the covalent connection: Chain connectivity and the catalytic reaction of PMM/PGM.
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Academic Article
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Observation of a chemically labile, noncovalent enzyme intermediate in the reaction of metal-dependent Aquifex pyrophilus KDO8PS by time-resolved mass spectrometry.
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Academic Article
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pH-dependent regulation of the a-subunit of H+-K+-ATPase (HKa2).
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Academic Article
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Isoform-specific regulation of Akt by PDGF-induced reactive oxygen species.
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Academic Article
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Simple synthesis of 1,3-cyclopentanedione derived probes for labeling sulfenic acid proteins.
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Academic Article
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Oxidation of Akt2 kinase promotes cell migration and regulates G1-S transition in the cell cycle.
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Academic Article
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A simple and effective strategy for labeling cysteine sulfenic acid in proteins by utilization of ß-ketoesters as cleavable probes.
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Academic Article
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Myosin heavy chain isoform expression in the Vastus Lateralis muscle of aging African green vervet monkeys.
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Academic Article
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Vascular bioactivation of nitroglycerin by aldehyde dehydrogenase-2: reaction intermediates revealed by crystallography and mass spectrometry.
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Concept
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Humans
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Concept
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Homeodomain Proteins
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Concept
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Metabolomics
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Concept
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Kidney
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Concept
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Ketone Oxidoreductases
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Concept
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Protein Kinase Inhibitors
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Concept
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Myosin Heavy Chains
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Concept
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Homeostasis
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Concept
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Mitogen-Activated Protein Kinase 9
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Concept
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Knee Joint
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Concept
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src-Family Kinases
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Concept
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Hydrogen Peroxide
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Concept
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Cyclic AMP-Dependent Protein Kinases
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Concept
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Ketones
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Concept
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AMP-Activated Protein Kinases
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Concept
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Head and Neck Neoplasms
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Concept
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H(+)-K(+)-Exchanging ATPase
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Concept
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History, Ancient
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Concept
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Kinetics
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Concept
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Chromatography, High Pressure Liquid
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Concept
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Kidney Tubules
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Concept
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Computational Biology
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Concept
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Cell Hypoxia
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Concept
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Lipoproteins, HDL
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Concept
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Hela Cells
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Concept
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Mitogen-Activated Protein Kinases
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Concept
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Drug Discovery
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Concept
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Kidney Diseases
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Concept
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Sequence Homology, Amino Acid
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Concept
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Cyclic AMP-Dependent Protein Kinase RIIalpha Subunit
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Concept
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Proteomics
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Concept
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Hydrolysis
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Concept
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Host-Pathogen Interactions
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Concept
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Hydrogen-Ion Concentration
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Concept
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Hindlimb Suspension
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Concept
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Gene Knockdown Techniques
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Concept
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Hip Joint
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Academic Article
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Molecular basis for the resistance of human mitochondrial 2-Cys peroxiredoxin 3 to hyperoxidation.
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Academic Article
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Thiol-blocking electrophiles interfere with labeling and detection of protein sulfenic acids.
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Academic Article
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Chemical approaches to detect and analyze protein sulfenic acids.
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Academic Article
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Effects of ionizing radiation on biological molecules--mechanisms of damage and emerging methods of detection.
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Academic Article
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Broad phenotypic changes associated with gain of radiation resistance in head and neck squamous cell cancer.
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Academic Article
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Ionizing radiation: mechanisms and therapeutics.
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Academic Article
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Strained cycloalkynes as new protein sulfenic acid traps.
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Academic Article
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Dissecting peroxiredoxin catalysis: separating binding, peroxidation, and resolution for a bacterial AhpC.
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Academic Article
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Mass spectrometry in studies of protein thiol chemistry and signaling: opportunities and caveats.
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Academic Article
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Energy metabolism in a matched model of radiation resistance for head and neck squamous cell cancer.
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Academic Article
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Activation of epidermal growth factor receptor is required for Chlamydia trachomatis development.
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Academic Article
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Analysis of DNA methylation and gene expression in radiation-resistant head and neck tumors.
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Academic Article
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Differential cytotoxic and radiosensitizing effects of silver nanoparticles on triple-negative breast cancer and non-triple-negative breast cells.
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Academic Article
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Cysteine-Mediated Redox Regulation of Cell Signaling in Chondrocytes Stimulated With Fibronectin Fragments.
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Academic Article
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Characterization of circulating APOL1 protein complexes in African Americans.
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Academic Article
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Biological chemistry and functionality of protein sulfenic acids and related thiol modifications.
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Academic Article
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Crystal Structure and Substrate Specificity of Human Thioesterase 2: INSIGHTS INTO THE MOLECULAR BASIS FOR THE MODULATION OF FATTY ACID SYNTHASE.
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Academic Article
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Oxidative Stress Promotes Peroxiredoxin Hyperoxidation and Attenuates Pro-survival Signaling in Aging Chondrocytes.
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Academic Article
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Calpain inhibition rescues troponin T3 fragmentation, increases Cav1.1, and enhances skeletal muscle force in aging sedentary mice.
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Academic Article
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The role of red blood cell S-nitrosation in nitrite bioactivation and its modulation by leucine and glucose.
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Academic Article
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The Human Pancreas as a Source of Protolerogenic Extracellular Matrix Scaffold for a New-generation Bioartificial Endocrine Pancreas.
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Academic Article
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The SAMHD1 dNTP Triphosphohydrolase Is Controlled by a Redox Switch.
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Academic Article
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Cardiac troponin T and fast skeletal muscle denervation in ageing.
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Academic Article
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Human Serum Albumin-Delivered [Au(PEt3)]+ Is a Potent Inhibitor of T Cell Proliferation.
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Academic Article
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Discovery of Heteroaromatic Sulfones As a New Class of Biologically Compatible Thiol-Selective Reagents.
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Academic Article
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Genome-Scale Modeling of NADPH-Driven ß-Lapachone Sensitization in Head and Neck Squamous Cell Carcinoma.
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Academic Article
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The Oxidative State of Cysteine Thiol 144 Regulates the SIRT6 Glucose Homeostat.
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Academic Article
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Modulators of Redox Metabolism in Head and Neck Cancer.
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Academic Article
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Platination of cysteine by an epidermal growth factor receptor kinase-targeted hybrid agent.
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Academic Article
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Novel hyperoxidation resistance motifs in 2-Cys peroxiredoxins.
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Academic Article
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Antioxidant treatment after injury suppresses second hit immune priming.
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Academic Article
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Mitochondria-targeted Probes for Imaging Protein Sulfenylation.
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Academic Article
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Initial biological evaluations of 18F-KS1, a novel ascorbate derivative to image oxidative stress in cancer.
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Academic Article
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H2O2 oxidation of cysteine residues in c-Jun N-terminal kinase 2 (JNK2) contributes to redox regulation in human articular chondrocytes.
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Academic Article
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Targeting NAD+ Metabolism to Enhance Radiation Therapy Responses.
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Academic Article
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Impaired Regeneration Potential in Urinary Stem Cells Diagnosed from the Patients with Diabetic Nephropathy.
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Academic Article
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Peroxiredoxins in Cancer and Response to Radiation Therapies.
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Academic Article
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Triphenylphosphonium-Derived Protein Sulfenic Acid Trapping Agents: Synthesis, Reactivity, and Effect on Mitochondrial Function.
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Academic Article
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Stearoyl-CoA Desaturase 1 Protects Ovarian Cancer Cells from Ferroptotic Cell Death.
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Academic Article
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Cysteine thiol oxidation on SIRT2 regulates inflammation in obese mice with sepsis.
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Academic Article
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The sympathetic nervous system regulates skeletal muscle motor innervation and acetylcholine receptor stability.
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Academic Article
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Mass Spectrometry in Advancement of Redox Precision Medicine.
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Academic Article
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Knee and Hip Joint Cartilage Damage from Combined Spaceflight Hazards of Low-Dose Radiation Less than 1 Gy and Prolonged Hindlimb Unloading.
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Academic Article
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Sulforaphane promotes chlamydial infection by suppressing mitochondrial protein oxidation and activation of complement C3.
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Academic Article
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Differential peroxiredoxin hyperoxidation regulates MAP kinase signaling in human articular chondrocytes.
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Academic Article
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Silver Nanoparticles Induce Mitochondrial Protein Oxidation in Lung Cells Impacting Cell Cycle and Proliferation.
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Academic Article
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Silver nanoparticles selectively treat triple-negative breast cancer cells without affecting non-malignant breast epithelial cells in vitro and in vivo.
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Academic Article
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Brain-specific repression of AMPKa1 alleviates pathophysiology in Alzheimer's model mice.
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Academic Article
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Discovery of Spilanthol Endoperoxide as a Redox Natural Compound Active against Mammalian Prx3 and Chlamydiatrachomatis Infection.
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Academic Article
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Introduction to approaches and tools for the evaluation of protein cysteine oxidation.
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Academic Article
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Sirtuin 6 (SIRT6) regulates redox homeostasis and signaling events in human articular chondrocytes.
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Academic Article
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3-D Human Renal Tubular Organoids Generated from Urine-Derived Stem Cells for Nephrotoxicity Screening.
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Academic Article
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Multi-Omics Analysis of Brain Metastasis Outcomes Following Craniotomy.
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Academic Article
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Dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction.
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Academic Article
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Endometrium and endometriosis tissue mitochondrial energy metabolism in a nonhuman primate model.
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Academic Article
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Integrated Redox Proteomic Analysis Highlights New Mechanisms of Sensitivity to Silver Nanoparticles.
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Academic Article
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Brain cell-derived exosomes in plasma serve as neurodegeneration biomarkers in male cynomolgus monkeys self-administrating oxycodone.
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Academic Article
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Spaceflight and hind limb unloading induces an arthritic phenotype in knee articular cartilage and menisci of rodents.
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Academic Article
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Use of Metabolomic Profiling to Understand Variability in Adiposity Changes Following an Intentional Weight Loss Intervention in Older Adults.
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Academic Article
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Protein expression alteration in hippocampus upon genetic repression of AMPKa isoforms.
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Academic Article
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The fatty acid elongase ELOVL6 regulates bortezomib resistance in multiple myeloma.
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Academic Article
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Call for Papers for the Special Issue on Natural Products in Redox Toxicology.
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Academic Article
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Personalized Genome-Scale Metabolic Models Identify Targets of Redox Metabolism in Radiation-Resistant Tumors.
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Academic Article
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MTHFD2 Blockade Enhances the Efficacy of ß-Lapachone Chemotherapy With Ionizing Radiation in Head and Neck Squamous Cell Cancer.
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Academic Article
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Sulfenic acid in human serum albumin: Reaction with thiols, oxidation and spontaneous decay.
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