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Academic Article
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Does angiotensin-(1-7) contribute to cardiac adaptation and preservation of endothelial function in heart failure?
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Academic Article
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Angiotensin-converting enzyme 2 is an essential regulator of heart function.
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Academic Article
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Vasopeptidase inhibition and Ang-(1-7) in the spontaneously hypertensive rat.
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Academic Article
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Hypertension-linked decrease in the expression of brain gamma-adducin.
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Academic Article
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Pregnancy enhances the angiotensin (Ang)-(1-7) vasodilator response in mesenteric arteries and increases the renal concentration and urinary excretion of Ang-(1-7).
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Academic Article
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Alterations in sympathetic ganglionic transmission in response to angiotensin II in (mRen2)27 transgenic rats.
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Academic Article
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Upregulation of angiotensin-converting enzyme 2 after myocardial infarction by blockade of angiotensin II receptors.
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Academic Article
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Renin-angiotensin system expression in rat bone marrow haematopoietic and stromal cells.
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Academic Article
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Vascular responses to Angiotensin-(1-7) during the estrous cycle.
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Academic Article
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Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2.
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Academic Article
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Angiotensin-(1-7) inhibits growth of cardiac myocytes through activation of the mas receptor.
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Academic Article
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Divergent regulation of circulating and intrarenal renin-angiotensin systems in response to long-term blockade.
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Academic Article
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Impaired heart rate baroreflex in older rats: role of endogenous angiotensin-(1-7) at the nucleus tractus solitarii.
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Academic Article
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Role of blood pressure reduction in prevention of cardiac and vascular hypertrophy.
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Academic Article
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Differential expression of nuclear AT1 receptors and angiotensin II within the kidney of the male congenic mRen2. Lewis rat.
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Academic Article
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Oxidative stress and glomerular filtration barrier injury: role of the renin-angiotensin system in the Ren2 transgenic rat.
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Academic Article
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Primary role of angiotensin-converting enzyme-2 in cardiac production of angiotensin-(1-7) in transgenic Ren-2 hypertensive rats.
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Academic Article
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Mineralocorticoid receptor blockade attenuates chronic overexpression of the renin-angiotensin-aldosterone system stimulation of reduced nicotinamide adenine dinucleotide phosphate oxidase and cardiac remodeling.
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Academic Article
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NADPH oxidase contributes to vascular inflammation, insulin resistance, and remodeling in the transgenic (mRen2) rat.
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Academic Article
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Increased hypothalamic angiotensin-(1-7) levels in rats with aortic coarctation-induced hypertension.
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Academic Article
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Modulation of reflex function by endogenous angiotensins in older transgenic rats with low glial angiotensinogen.
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Academic Article
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Angiotensin-(1-12) is an alternate substrate for angiotensin peptide production in the heart.
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Academic Article
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Localization of the novel angiotensin peptide, angiotensin-(1-12), in heart and kidney of hypertensive and normotensive rats.
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Academic Article
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Effect of renin inhibition and AT1R blockade on myocardial remodeling in the transgenic Ren2 rat.
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Academic Article
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Angiotensin-(1-7) and baroreflex function in nucleus tractus solitarii of (mRen2)27 transgenic rats.
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Academic Article
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Increased expression of angiotensin converting enzyme 2 in conjunction with reduction of neointima by angiotensin II type 1 receptor blockade.
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Academic Article
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Renin inhibition attenuates insulin resistance, oxidative stress, and pancreatic remodeling in the transgenic Ren2 rat.
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Academic Article
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MAP kinase/phosphatase pathway mediates the regulation of ACE2 by angiotensin peptides.
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Academic Article
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Regulation of ACE2 in cardiac myocytes and fibroblasts.
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Academic Article
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Exercise training prevents development of cardiac contractile dysfunction in hypertensive TG (mREN-2)27 rats.
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Academic Article
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Mineralocorticoid receptor antagonism attenuates glomerular filtration barrier remodeling in the transgenic Ren2 rat.
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Academic Article
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Differential effect of low dose thiazides on the Renin Angiotensin system in genetically hypertensive and normotensive rats.
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Academic Article
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Nebivolol reduces proteinuria and renal NADPH oxidase-generated reactive oxygen species in the transgenic Ren2 rat.
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Academic Article
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Rosuvastatin ameliorates the development of pulmonary arterial hypertension in the transgenic (mRen2)27 rat.
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Academic Article
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Decreased cardiac Ang-(1-7) is associated with salt-induced cardiac remodeling and dysfunction.
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Academic Article
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New physiological concepts of the renin-angiotensin system from the investigation of precursors and products of angiotensin I metabolism.
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Academic Article
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Nebivolol attenuates maladaptive proximal tubule remodeling in transgenic rats.
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Academic Article
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Uptake and metabolism of the novel peptide angiotensin-(1-12) by neonatal cardiac myocytes.
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Academic Article
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Nebivolol improves insulin sensitivity in the TGR(Ren2)27 rat.
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Academic Article
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Sex differences in baroreflex sensitivity, heart rate variability, and end organ damage in the TGR(mRen2)27 rat.
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Academic Article
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Chymase-dependent generation of angiotensin II from angiotensin-(1-12) in human atrial tissue.
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Academic Article
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Restoration of the blood pressure circadian rhythm by direct renin inhibition and blockade of angiotensin II receptors in mRen2.Lewis hypertensive rats.
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Academic Article
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Nebivolol improves diastolic dysfunction and myocardial remodeling through reductions in oxidative stress in the transgenic (mRen2) rat.
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Academic Article
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Combination of direct renin inhibition with angiotensin type 1 receptor blockade improves aldosterone but does not improve kidney injury in the transgenic Ren2 rat.
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Academic Article
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Predominance of AT(1) blockade over mas-mediated angiotensin-(1-7) mechanisms in the regulation of blood pressure and renin-angiotensin system in mRen2.Lewis rats.
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Academic Article
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Blood pressure-independent attenuation of cardiac hypertrophy by AT(1)R-AS gene therapy.
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Academic Article
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Angiotensin receptors contribute to blood pressure homeostasis in salt-depleted SHR.
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Academic Article
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Commentary on Tikellis et al: There is more to discover about angiotensin-converting enzyme.
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Academic Article
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Characterization of angiotensin-(1-7) receptor subtype in mesenteric arteries.
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Academic Article
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Enhanced renal immunocytochemical expression of ANG-(1-7) and ACE2 during pregnancy.
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Academic Article
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Estrogen or the AT1 antagonist olmesartan reverses the development of profound hypertension in the congenic mRen2. Lewis rat.
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Academic Article
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Cardiac angiotensin-(1-7) in ischemic cardiomyopathy.
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Academic Article
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Abrogation of oxidative stress improves insulin sensitivity in the Ren-2 rat model of tissue angiotensin II overexpression.
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Academic Article
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Central depletion of angiotensinogen is associated with elevated AT1 receptors in the SFO and PVN.
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Academic Article
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Myocardial infarction increases ACE2 expression in rat and humans.
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Academic Article
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Angiotensin II AT1 receptors regulate ACE2 and angiotensin-(1-7) expression in the aorta of spontaneously hypertensive rats.
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Academic Article
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Protection from angiotensin II-induced cardiac hypertrophy and fibrosis by systemic lentiviral delivery of ACE2 in rats.
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Academic Article
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Growth, metabolism, and blood pressure disturbances during aging in transgenic rats with altered brain renin-angiotensin systems.
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Academic Article
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Distinct roles for ANG II and ANG-(1-7) in the regulation of angiotensin-converting enzyme 2 in rat astrocytes.
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Academic Article
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Effects of renin-angiotensin system blockade on renal angiotensin-(1-7) forming enzymes and receptors.
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Academic Article
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Effect of angiotensin II blockade on a new congenic model of hypertension derived from transgenic Ren-2 rats.
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Academic Article
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Proximal tubule microvilli remodeling and albuminuria in the Ren2 transgenic rat.
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Academic Article
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Baroreceptor reflex regulation in anesthetized transgenic rats with low glia-derived angiotensinogen.
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Academic Article
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Rosuvastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, decreases cardiac oxidative stress and remodeling in Ren2 transgenic rats.
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Academic Article
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Rats with low brain angiotensinogen do not exhibit insulin resistance during early aging.
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Academic Article
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Angiotensin II-mediated oxidative stress promotes myocardial tissue remodeling in the transgenic (mRen2) 27 Ren2 rat.
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Academic Article
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Aging and the brain renin-angiotensin system: insights from studies in transgenic rats.
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Academic Article
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ACE2 and ANG-(1-7) in the rat uterus during early and late gestation.
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Academic Article
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Angiotensin II-induced skeletal muscle insulin resistance mediated by NF-kappaB activation via NADPH oxidase.
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Academic Article
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Attenuation of NADPH oxidase activation and glomerular filtration barrier remodeling with statin treatment.
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Academic Article
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Estrogen, nitric oxide, and hypertension differentially modulate agonist-induced contractile responses in female transgenic (mRen2)27 hypertensive rats.
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Academic Article
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Injections of angiotensin-converting enzyme 2 inhibitor MLN4760 into nucleus tractus solitarii reduce baroreceptor reflex sensitivity for heart rate control in rats.
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Academic Article
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Low-dose spironolactone reduces reactive oxygen species generation and improves insulin-stimulated glucose transport in skeletal muscle in the TG(mRen2)27 rat.
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Academic Article
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Angiotensin II-induced non-alcoholic fatty liver disease is mediated by oxidative stress in transgenic TG(mRen2)27(Ren2) rats.
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Academic Article
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Mineralocorticoid receptor antagonism attenuates vascular apoptosis and injury via rescuing protein kinase B activation.
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Academic Article
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Differential regulation of angiotensin-(1-12) in plasma and cardiac tissue in response to bilateral nephrectomy.
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Academic Article
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Direct renin inhibition improves systemic insulin resistance and skeletal muscle glucose transport in a transgenic rodent model of tissue renin overexpression.
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Academic Article
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Oxidative stress-mediated mitochondrial dysfunction contributes to angiotensin II-induced nonalcoholic fatty liver disease in transgenic Ren2 rats.
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Academic Article
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Chronic immunoneutralization of brain angiotensin-(1-12) lowers blood pressure in transgenic (mRen2)27 hypertensive rats.
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Academic Article
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Comparative effect of direct renin inhibition and AT1R blockade on glomerular filtration barrier injury in the transgenic Ren2 rat.
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Academic Article
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Inhibition of angiotensin-converting enzyme 2 exacerbates cardiac hypertrophy and fibrosis in Ren-2 hypertensive rats.
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Academic Article
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Angiotensin-(1-12) requires angiotensin converting enzyme and AT1 receptors for cardiovascular actions within the solitary tract nucleus.
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Academic Article
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Advances in the renin angiotensin system focus on angiotensin-converting enzyme 2 and angiotensin-(1-7).
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Academic Article
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Salt-induced renal injury in spontaneously hypertensive rats: effects of nebivolol.
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Academic Article
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Angiotensin II activation of mTOR results in tubulointerstitial fibrosis through loss of N-cadherin.
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Academic Article
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Attenuation of hypertension-mediated glomerulosclerosis in conjunction with increased angiotensin (1-7).
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Academic Article
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Mineralocorticoid receptor-dependent proximal tubule injury is mediated by a redox-sensitive mTOR/S6K1 pathway.
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Academic Article
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Cardiac kallikrein-kinin system is upregulated in chronic volume overload and mediates an inflammatory induced collagen loss.
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Academic Article
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Nebivolol reduces cardiac angiotensin II, associated oxidative stress and fibrosis but not arterial pressure in salt-loaded spontaneously hypertensive rats.
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Academic Article
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Hemodynamic and hormonal changes to dual renin-angiotensin system inhibition in experimental hypertension.
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Concept
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Rats, Inbred F344
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Concept
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Rats, Inbred BN
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Concept
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Rats, Inbred SHR
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Concept
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Rats, Inbred WKY
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Concept
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Rats, Inbred Strains
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Concept
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Rats, Inbred Lew
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Concept
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Rats
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Concept
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Rats, Mutant Strains
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Concept
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Rats, Wistar
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Concept
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Rats, Sprague-Dawley
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Concept
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Rats, Transgenic
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Academic Article
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Renin inhibition and AT(1)R blockade improve metabolic signaling, oxidant stress and myocardial tissue remodeling.
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Academic Article
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Primacy of angiotensin converting enzyme in angiotensin-(1-12) metabolism.
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Academic Article
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Characterization of the cardiac renin angiotensin system in oophorectomized and estrogen-replete mRen2.Lewis rats.
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Academic Article
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Salt loading exacerbates diastolic dysfunction and cardiac remodeling in young female Ren2 rats.
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Academic Article
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Salt Loading Promotes Kidney Injury via Fibrosis in Young Female Ren2 Rats.
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Academic Article
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Comparative effects of a novel angiotensin-converting enzyme inhibitor versus captopril on plasma angiotensins after myocardial infarction.
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Academic Article
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Modulation of cardiac L-type Ca2+ current by angiotensin-(1-7): normal versus heart failure.
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Academic Article
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Increased fibroblast chymase production mediates procollagen autophagic digestion in volume overload.
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Academic Article
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Cardiac angiotensin-(1-12) expression and systemic hypertension in rats expressing the human angiotensinogen gene.
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Academic Article
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Mast Cell Inhibition Attenuates Cardiac Remodeling and Diastolic Dysfunction in Middle-aged, Ovariectomized Fischer 344 × Brown Norway Rats.
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Academic Article
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Primacy of cardiac chymase over angiotensin converting enzyme as an angiotensin-(1-12) metabolizing enzyme.
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Academic Article
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Low glial angiotensinogen improves body habitus, diastolic function, and exercise tolerance in aging male rats.
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Academic Article
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Effect of Age, Estrogen Status, and Late-Life GPER Activation on Cardiac Structure and Function in the Fischer344×Brown Norway Female Rat.
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Academic Article
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Cellular basis of angiotensin-(1-7)-induced augmentation of left ventricular functional performance in heart failure.
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Grant
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ANGIOTENSIN 1-7 IN THE SPONTANEOUSLY HYPERTENSIVE
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Grant
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Vaso-Hormonal Mechanisms in Hypertension
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Academic Article
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Blunting of cardioprotective actions of estrogen in female rodent heart linked to altered expression of cardiac tissue chymase and ACE2.
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Academic Article
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Blunting of estrogen modulation of cardiac cellular chymase/RAS activity and function in SHR.
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Academic Article
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Critical role of the chymase/angiotensin-(1-12) axis in modulating cardiomyocyte contractility.
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Academic Article
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Estrogen modulates the differential expression of cardiac myocyte chymase isoforms and diastolic function.
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Academic Article
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G-Protein-Coupled Estrogen Receptor Agonist G1 Improves Diastolic Function and Attenuates Cardiac Renin-Angiotensin System Activation in Estrogen-Deficient Hypertensive Rats.
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