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One or more keywords matched the following properties of Singh, Ravi
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overview My interdisciplinary background in biomedical nanotechnology, a field lying at the interface of biomedicine, chemistry, physics and materials science, brings together ideas and techniques from these disciplines. By studying and manipulating the bio-nano interface, I work to facilitate the translation of proof of principle experiments into clinical applications of well-defined materials for cancer therapy and diagnostic use. Most recently, my group showed that carbon nanotubes can be used to target breast and brain tumors, deliver genes and cancer therapeutics, and that appropriately functionalized carbon nanotubes are safe for blood born delivery. Additionally, we demonstrated that unmodified silver nanoparticles act as a self-therapeutic agent with a combination of selective cytotoxicity and radiation dose-enhancement effects toward triple negative breast cancer at doses that are nontoxic to noncancerous breast and other cells. I am dedicated to developing new tools to improve outcomes for cancer treatment and diagnosis.
One or more keywords matched the following items that are connected to Singh, Ravi
Item TypeName
Academic Article Designer adenoviruses for nanomedicine and nanodiagnostics.
Academic Article The resistance of breast cancer stem cells to conventional hyperthermia and their sensitivity to nanoparticle-mediated photothermal therapy.
Concept Metal Nanoparticles
Concept Nanoparticles
Academic Article Differential cytotoxic and radiosensitizing effects of silver nanoparticles on triple-negative breast cancer and non-triple-negative breast cells.
Grant Advanced instrumentation for pre-clinical evaluation of magnetic nanoparticle heating
Grant Image guided delivery of nanoparticles for drug delivery and enhanced photothermal therapy
Academic Article Targeting Cancer Stem Cells with Nanoparticle-Enabled Therapies.
Academic Article Heat localization for targeted tumor treatment with nanoscale near-infrared radiation absorbers.
Academic Article Nanoparticles for cancer imaging: The good, the bad, and the promise.
Academic Article Liposome-protamine-DNA nanoparticle-mediated delivery of short hairpin RNA targeting brachyury inhibits chordoma cell growth
Academic Article Large-Pore Functionalized Mesoporous Silica Nanoparticles as Drug Delivery Vector for a Highly Cytotoxic Hybrid Platinum-Acridine Anticancer Agent.
Grant Development of a novel therapeutic agent that exploits specific vulnerabilities in claudin low breast cancer
Academic Article Heterogeneous Responses of Ovarian Cancer Cells to Silver Nanoparticles as a Single Agent and in Combination with Cisplatin.
Academic Article Synthesis, Purification, Characterization, and Imaging of Cy3-Functionalized Fluorescent Silver Nanoparticles in 2D and 3D Tumor Models.
Academic Article Silver Nanoparticles Induce Mitochondrial Protein Oxidation in Lung Cells Impacting Cell Cycle and Proliferation.
Academic Article Silver nanoparticles selectively treat triple-negative breast cancer cells without affecting non-malignant breast epithelial cells in vitro and in vivo.
Academic Article Semiconducting polymer nanoparticles for photothermal ablation of colorectal cancer organoids.
Academic Article Oxaliplatin-resistant colorectal cancer models for nanoparticle hyperthermia.
Academic Article The mechanism of cell death induced by silver nanoparticles is distinct from silver cations.
Academic Article Low Doses of Silver Nanoparticles Selectively Induce Lipid Peroxidation and Proteotoxic Stress in Mesenchymal Subtypes of Triple-Negative Breast Cancer.
Academic Article Combined Photothermal and Ionizing Radiation Sensitization of Triple-Negative Breast Cancer Using Triangular Silver Nanoparticles.
Academic Article Integrated Redox Proteomic Analysis Highlights New Mechanisms of Sensitivity to Silver Nanoparticles.
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