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One or more keywords matched the following properties of Singh, Ravi
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overview My interdisciplinary background in biomedical nanotechnology, a field lying at the interface of biomedicine, chemistry, physics and materials science, brings together ideas and techniques from these disciplines. By studying and manipulating the bio-nano interface, I work to facilitate the translation of proof of principle experiments into clinical applications of well-defined materials for cancer therapy and diagnostic use. Most recently, my group showed that carbon nanotubes can be used to target breast and brain tumors, deliver genes and cancer therapeutics, and that appropriately functionalized carbon nanotubes are safe for blood born delivery. Additionally, we demonstrated that unmodified silver nanoparticles act as a self-therapeutic agent with a combination of selective cytotoxicity and radiation dose-enhancement effects toward triple negative breast cancer at doses that are nontoxic to noncancerous breast and other cells. I am dedicated to developing new tools to improve outcomes for cancer treatment and diagnosis.
One or more keywords matched the following items that are connected to Singh, Ravi
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Academic Article Development of iron-containing multiwalled carbon nanotubes for MR-guided laser-induced thermotherapy.
Academic Article Treatment of breast cancer through the application of irreversible electroporation using a novel minimally invasive single needle electrode.
Academic Article The resistance of breast cancer stem cells to conventional hyperthermia and their sensitivity to nanoparticle-mediated photothermal therapy.
Concept Breast Neoplasms
Academic Article Differential cytotoxic and radiosensitizing effects of silver nanoparticles on triple-negative breast cancer and non-triple-negative breast cells.
Academic Article Targeting breast cancer with sugar-coated carbon nanotubes.
Academic Article Design and cellular studies of a carbon nanotube-based delivery system for a hybrid platinum-acridine anticancer agent.
Academic Article Regulation of alternative splicing of Bcl-x by BC200 contributes to breast cancer pathogenesis.
Grant Tumor Targeting and Diagnostic Applications of Glycosylated Nanotubes
Grant Tumor Targeting and Diagnostic Applications of Glycosylated Nanotubes
Grant Development of a novel therapeutic agent that exploits specific vulnerabilities in claudin low breast cancer
Academic Article Loss of XIST in Breast Cancer Activates MSN-c-Met and Reprograms Microglia via Exosomal miRNA to Promote Brain Metastasis.
Academic Article Synthesis, Purification, Characterization, and Imaging of Cy3-Functionalized Fluorescent Silver Nanoparticles in 2D and 3D Tumor Models.
Academic Article Silver nanoparticles selectively treat triple-negative breast cancer cells without affecting non-malignant breast epithelial cells in vitro and in vivo.
Academic Article Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer.
Academic Article Low Doses of Silver Nanoparticles Selectively Induce Lipid Peroxidation and Proteotoxic Stress in Mesenchymal Subtypes of Triple-Negative Breast Cancer.
Academic Article Combined Photothermal and Ionizing Radiation Sensitization of Triple-Negative Breast Cancer Using Triangular Silver Nanoparticles.
Academic Article Correction: Loss of XIST in Breast Cancer Activates MSN-c-Met and Reprograms Microglia via Exosomal miRNA to Promote Brain Metastasis.
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