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Bonkovsky, Herbert
One or more keywords matched the following items that are connected to Bonkovsky, Herbert
Item TypeName
Concept Heme
Concept Heme Oxygenase (Decyclizing)
Concept Heme Oxygenase-1
Academic Article Porphyrogenic properties of the terpenes camphor, pinene, and thujone (with a note on historic implications for absinthe and the illness of Vincent van Gogh).
Academic Article Intravenous heme-albumin in acute intermittent porphyria: evidence for repletion of hepatic hemoproteins and regulatory heme pools.
Academic Article Immunochemical studies of haem oxygenase. Preparation and characterization of antibodies to chick liver haem oxygenase and their use in detecting and quantifying amounts of haem oxygenase protein.
Academic Article Synergistic induction of delta-aminolevulinate synthase by glutethimide and iron: relationship to the synergistic induction of heme oxygenase.
Academic Article Cloning, sequencing and expression of cDNA for chick liver haem oxygenase. Comparison of avian and mammalian cDNAs and deduced proteins.
Academic Article Purification and characterization of heme oxygenase from chick liver. Comparison of the avian and mammalian enzymes.
Academic Article Mechanism of synergistic induction of hepatic heme oxygenase by glutethimide and iron: studies in cultured chick embryo liver cells.
Academic Article The porphyrias.
Academic Article Heme catabolism in cultured hepatocytes: evidence that heme oxygenase is the predominant pathway and that a proportion of synthesized heme is converted rapidly to biliverdin.
Academic Article Mechanism of iron potentiation of hepatic uroporphyria: studies in cultured chick embryo liver cells.
Academic Article Hepatic microsomal function in rats with chronic dietary iron overload.
Academic Article Uroporphyrin accumulation produced by halogenated biphenyls in chick-embryo hepatocytes. Reversal of the accumulation by piperonyl butoxide.
Academic Article Hepatic heme and drug metabolism in rats with chronic mountain sickness.
Academic Article Regulation of hepatic haem metabolism. Disparate mechanisms of induction of haem oxygenase by drugs and metals.
Academic Article Tryptophan 2,3-dioxygenase in chick embryo hepatocytes: studies in ovo and in culture.
Academic Article Microassay of heme oxygenase by high-performance liquid chromatography: application to assay of needle biopsies of human liver.
Academic Article Haem synthesis from exogenous 5-aminolaevulinate in cultured chick-embryo hepatocytes. Effects of inducers of cytochromes P-450.
Academic Article Hepatic heme synthesis in a new model of experimental hemochromatosis: studies in rats fed finely divided elemental iron.
Academic Article High-performance liquid chromatographic separation and quantitation of tetrapyrroles from biological materials.
Academic Article Conversion of 5-aminolaevulinate into haem by homogenates of human liver. Comparison with rat and chick-embryo liver homogenates.
Academic Article Formation of cytochrome P-450 containing haem or cobalt-protoporphyrin in liver homogenates of rats treated with phenobarbital and allylisopropylacetamide.
Academic Article Tissue distribution of zinc-mesoporphyrin in rats: relationship to inhibition of heme oxygenase.
Academic Article Effects of mifepristone (RU-486) on heme metabolism and cytochromes P-450 in cultured chick embryo liver cells, possible implications for acute porphyria.
Academic Article Repression of ALA synthase by heme and zinc-mesoporphyrin in a chick embryo liver cell culture model of acute porphyria.
Academic Article The post-translational processing of myeloperoxidase is regulated by the availability of heme.
Academic Article Differential effects of metalloporphyrins on messenger RNA levels of delta-aminolevulinate synthase and heme oxygenase. Studies in cultured chick embryo liver cells.
Academic Article Effects of hemopexin on heme-mediated repression of 5-aminolevulinate synthase and induction of heme oxygenase in cultured hepatocytes.
Academic Article Induction of heme oxygenase in intestinal epithelial cells: studies in Caco-2 cell cultures.
Academic Article 3,5,5-Trimethylhexanoylferrocene induction of heme oxygenase activity in normal hepatocytes.
Academic Article Repression of hepatic delta-aminolevulinate synthase by heme and metalloporphyrins: relationship to inhibition of heme oxygenase.
Academic Article Advances in understanding and treating 'the little imitator,' acute porphyria.
Academic Article Molecular basis for heme-dependent induction of heme oxygenase in primary cultures of chick embryo hepatocytes. Demonstration of acquired refractoriness to heme.
Academic Article Induction of heme oxygenase-1 in LMH cells. Comparison of LMH cells to primary cultures of chick embryo liver cells.
Academic Article An update on iron metabolism: summary of the Fifth International Conference on Disorders of Iron Metabolism.
Academic Article Hepatic 5-aminolevulinic acid synthase mRNA stability is modulated by inhibitors of heme biosynthesis and by metalloporphyrins.
Academic Article Haemopexin and uptake of haem by liver cells.
Academic Article Mechanism of induction of heme oxygenase by metalloporphyrins in primary chick embryo liver cells: evidence against a stress-mediated response.
Academic Article Regulation of expression of the human heme oxygenase-1 gene in transfected chick embryo liver cell cultures.
Academic Article Molecular cloning, characterization, and expression of the chicken heme oxygenase-1 gene in transfected primary cultures of chick embryo liver cells.
Academic Article Mechanism of sodium arsenite-mediated induction of heme oxygenase-1 in hepatoma cells. Role of mitogen-activated protein kinases.
Academic Article The value of intravenous heme-albumin and plasmapheresis in reducing postoperative complications of orthotopic liver transplantation for erythropoietic protoporphyria.
Academic Article Increased heme oxygenase-1 gene expression in liver cells and splanchnic organs from portal hypertensive rats.
Academic Article Heme oxygenase: recent advances in understanding its regulation and role.
Academic Article Heme biosynthesis in a chicken hepatoma cell line (LMH): comparison with primary chick embryo liver cells (CELC).
Academic Article Effects of phenylarsine oxide on expression of heme oxygenase-1 reporter constructs in transiently transfected cultures of chick embryo liver cells.
Academic Article Induction of the heme oxygenase-1 gene by metalloporphyrins.
Academic Article Upstream regulatory elements in chick heme oxygenase-1 promoter: a study in primary cultures of chick embryo liver cells.
Academic Article Increased heme oxygenase activity in splanchnic organs from portal hypertensive rats: role in modulating mesenteric vascular reactivity.
Academic Article Urea and hypertonicity increase expression of heme oxygenase-1 in murine renal medullary cells.
Academic Article Induction of heme oxygenase-1 by phenylarsine oxide. Studies in cultured primary liver cells.
Academic Article Benefits of chronic plasmapheresis and intravenous heme-albumin in erythropoietic protoporphyria after orthotopic liver transplantation.
Academic Article Mapping of the chick heme oxygenase-1 proximal promoter for responsiveness to metalloporphyrins.
Academic Article Vascular endothelial growth factor increases heme oxygenase-1 protein expression in the chick embryo chorioallantoic membrane.
Academic Article Identification of key elements that are responsible for heme-mediated induction of the avian heme oxygenase-1 gene.
Academic Article Hepatic porphyrias: diagnosis and management.
Academic Article Role of Bach-1 in regulation of heme oxygenase-1 in human liver cells: insights from studies with small interfering RNAS.
Academic Article Haem repression of the housekeeping 5-aminolaevulinic acid synthase gene in the hepatoma cell line LMH.
Academic Article Neurovisceral porphyrias: what a hematologist needs to know.
Academic Article HCV proteins increase expression of heme oxygenase-1 (HO-1) and decrease expression of Bach1 in human hepatoma cells.
Academic Article Role of Bach1 and Nrf2 in up-regulation of the heme oxygenase-1 gene by cobalt protoporphyrin.
Academic Article Genetic aspects of porphyria cutanea tarda.
Academic Article Marked hyperbilirubinemia associated with the heme oxygenase-1 gene promoter microsatellite polymorphism in a boy with autoimmune hemolytic anemia.
Academic Article Reciprocal effects of micro-RNA-122 on expression of heme oxygenase-1 and hepatitis C virus genes in human hepatocytes.
Academic Article Zinc mesoporphyrin induces rapid and marked degradation of the transcription factor Bach1 and up-regulates HO-1.
Academic Article Tissue-specific expression of ALA synthase-1 and heme oxygenase-1 and their expression in livers of rats chronically exposed to ethanol.
Academic Article Case records of the Massachusetts General Hospital. Case 20-2008. A 57-year-old woman with abdominal pain and weakness after gastric bypass surgery.
Academic Article Effects of silymarin on hepatitis C virus and haem oxygenase-1 gene expression in human hepatoma cells.
Academic Article Differential regulation of human ALAS1 mRNA and protein levels by heme and cobalt protoporphyrin.
Academic Article Iron increases HMOX1 and decreases hepatitis C viral expression in HCV-expressing cells.
Academic Article MicroRNA-196 represses Bach1 protein and hepatitis C virus gene expression in human hepatoma cells expressing hepatitis C viral proteins.
Academic Article Genetic variations in heme oxygenase-1 and chronic hepatitis.
Academic Article Structural analysis of heme proteins: implications for design and prediction.
Academic Article Legalon-SIL downregulates HCV core and NS5A in human hepatocytes expressing full-length HCV.
Academic Article Lon peptidase 1 (LONP1)-dependent breakdown of mitochondrial 5-aminolevulinic acid synthase protein by heme in human liver cells.
Academic Article The let-7 microRNA enhances heme oxygenase-1 by suppressing Bach1 and attenuates oxidant injury in human hepatocytes.
Academic Article Heme status affects human hepatic messenger RNA and microRNA expression.
Academic Article Circadian rhythms in acute intermittent porphyria--a pilot study.
Academic Article Porphyrin and heme metabolism and the porphyrias.
Academic Article Proteomic strategy for probing complementary lethality of kinase inhibitors against pancreatic cancer.
Academic Article Clinically important features of porphyrin and heme metabolism and the porphyrias.
Academic Article Leukocyte expression of heme oxygenase-1 [hmox1] varies inversely with severity of tricuspid regurgitation in acute pulmonary embolism.
Academic Article Genetic factors that affect nonalcoholic fatty liver disease: A systematic clinical review.
Grant Regulation of Hepatic Heme Metabolism
Grant HEPATIC HEME, CYTOCHROME P-450 AND DRUG METABOLISM
Grant Effect of Heme on mRNA and miRNA Profile
Academic Article Porphyria.
Academic Article Porphyrin-Induced Protein Oxidation and Aggregation as a Mechanism of Porphyria-Associated Cell Injury.
Academic Article Pathogenesis and clinical features of the acute hepatic porphyrias (AHPs).
Academic Article Pilot study of mitochondrial bioenergetics in subjects with acute porphyrias.
Academic Article Sex differences in vascular reactivity in mesenteric arteries from a mouse model of acute intermittent porphyria.
Academic Article Benefits of prophylactic heme therapy in severe acute intermittent porphyria.
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  • Heme