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Search Results to Mark C. Chappell, Ph.D.

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One or more keywords matched the following items that are connected to Chappell, Mark

Item TypeName
Academic Article Angiotensin-converting enzyme 2 is an essential regulator of heart function.
Academic Article Vasopeptidase inhibition and Ang-(1-7) in the spontaneously hypertensive rat.
Academic Article A local pancreatic renin-angiotensin system: endocrine and exocrine roles.
Academic Article Novel aspects of the renal renin-angiotensin system: angiotensin-(1-7), ACE2 and blood pressure regulation.
Academic Article Angiotensin converting enzyme-independent angiotensin ii production by chymase is up-regulated in the ischemic kidney in renovascular hypertension.
Academic Article Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2.
Academic Article Adenovirus-mediated small-interference RNA for in vivo silencing of angiotensin AT1a receptors in mouse brain.
Academic Article Differential expression of nuclear AT1 receptors and angiotensin II within the kidney of the male congenic mRen2. Lewis rat.
Academic Article Growth hormone replacement attenuates diastolic dysfunction and cardiac angiotensin II expression in senescent rats.
Academic Article Primary role of angiotensin-converting enzyme-2 in cardiac production of angiotensin-(1-7) in transgenic Ren-2 hypertensive rats.
Academic Article Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice.
Academic Article Ovariectomy is protective against renal injury in the high-salt-fed older mRen2. Lewis rat.
Academic Article Angiotensin-(1-7) prevents activation of NADPH oxidase and renal vascular dysfunction in diabetic hypertensive rats.
Academic Article Angiotensin-(1-12) is an alternate substrate for angiotensin peptide production in the heart.
Academic Article Localization of the novel angiotensin peptide, angiotensin-(1-12), in heart and kidney of hypertensive and normotensive rats.
Academic Article New angiotensins.
Academic Article Chronic treatment with the G protein-coupled receptor 30 agonist G-1 decreases blood pressure in ovariectomized mRen2.Lewis rats.
Academic Article Major role for ACE-independent intrarenal ANG II formation in type II diabetes.
Academic Article Decreased cardiac Ang-(1-7) is associated with salt-induced cardiac remodeling and dysfunction.
Academic Article Angiotensin-(1-7)-angiotensin-converting enzyme 2 attenuates reactive oxygen species formation to angiotensin II within the cell nucleus.
Academic Article Increased angiotensin II in the mesometrial triangle of a transgenic rat model of preeclampsia.
Academic Article Acute AT(1)-receptor blockade reverses the hemodynamic and baroreflex impairment in adult sheep exposed to antenatal betamethasone.
Academic Article Nuclear angiotensin-(1-7) receptor is functionally coupled to the formation of nitric oxide.
Academic Article Glucocorticoid-induced fetal programming alters the functional complement of angiotensin receptor subtypes within the kidney.
Academic Article Uptake and metabolism of the novel peptide angiotensin-(1-12) by neonatal cardiac myocytes.
Academic Article Vasodilation in response to the GPR30 agonist G-1 is not different from estradiol in the mRen2.Lewis female rat.
Academic Article Long-term systemic angiotensin II type 1 receptor blockade regulates mRNA expression of dorsomedial medulla renin-angiotensin system components.
Academic Article Estrogen receptor GPR30 reduces oxidative stress and proteinuria in the salt-sensitive female mRen2.Lewis rat.
Academic Article Angiotensin-converting enzyme 2 deficiency is associated with impaired gestational weight gain and fetal growth restriction.
Academic Article Evidence that the G protein-coupled membrane receptor GPR30 contributes to the cardiovascular actions of estrogen.
Academic Article Chymase-dependent generation of angiotensin II from angiotensin-(1-12) in human atrial tissue.
Academic Article Angiotensin-(1-7) deficiency and baroreflex impairment precede the antenatal Betamethasone exposure-induced elevation in blood pressure.
Academic Article In vivo expression of angiotensin-(1-7) lowers blood pressure and improves baroreflex function in transgenic (mRen2)27 rats.
Academic Article Unraveling the glomerular RAS: one peptidase at a time.
Academic Article Central angiotensin-(1-7) improves vagal function independent of blood pressure in hypertensive (mRen2)27 rats.
Academic Article Angiotensin receptors contribute to blood pressure homeostasis in salt-depleted SHR.
Academic Article Characterization of angiotensin-(1-7) receptor subtype in mesenteric arteries.
Academic Article Enhanced renal immunocytochemical expression of ANG-(1-7) and ACE2 during pregnancy.
Academic Article Estrogen or the AT1 antagonist olmesartan reverses the development of profound hypertension in the congenic mRen2. Lewis rat.
Academic Article Cardiac angiotensin-(1-7) in ischemic cardiomyopathy.
Academic Article Depletion of tissue angiotensin-converting enzyme differentially influences the intrarenal and urinary expression of angiotensin peptides.
Academic Article A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury.
Academic Article Distinct roles for ANG II and ANG-(1-7) in the regulation of angiotensin-converting enzyme 2 in rat astrocytes.
Academic Article Does the angiotensin-converting enzyme (ACE)/ACE2 balance contribute to the fate of angiotensin peptides in programmed hypertension?
Academic Article Effects of renin-angiotensin system blockade on renal angiotensin-(1-7) forming enzymes and receptors.
Academic Article Effect of angiotensin II blockade on a new congenic model of hypertension derived from transgenic Ren-2 rats.
Academic Article Estrogen and salt sensitivity in the female mRen(2). Lewis rat.
Academic Article Angiotensin metabolism in renal proximal tubules, urine, and serum of sheep: evidence for ACE2-dependent processing of angiotensin II.
Academic Article Discoordinate regulation of renal nitric oxide synthase isoforms in ovariectomized mRen2. Lewis rats.
Academic Article Progressive diastolic dysfunction in the female mRen(2). Lewis rat: influence of salt and ovarian hormones.
Academic Article Injections of angiotensin-converting enzyme 2 inhibitor MLN4760 into nucleus tractus solitarii reduce baroreceptor reflex sensitivity for heart rate control in rats.
Academic Article Distinct roles for angiotensin-converting enzyme 2 and carboxypeptidase A in the processing of angiotensins within the murine heart.
Academic Article Differential effects of sex steroids in young and aged female mRen2.Lewis rats: a model of estrogen and salt-sensitive hypertension.
Academic Article Plasma and renal renin concentrations in adult sheep after prenatal betamethasone exposure.
Academic Article Gender differences in the effects of antenatal betamethasone exposure on renal function in adult sheep.
Academic Article Alterations in circulatory and renal angiotensin-converting enzyme and angiotensin-converting enzyme 2 in fetal programmed hypertension.
Academic Article Differential regulation of angiotensin-(1-12) in plasma and cardiac tissue in response to bilateral nephrectomy.
Academic Article Nuclear angiotensin II type 2 (AT2) receptors are functionally linked to nitric oxide production.
Academic Article Chronic immunoneutralization of brain angiotensin-(1-12) lowers blood pressure in transgenic (mRen2)27 hypertensive rats.
Academic Article The angiotensin II-AT1 receptor stimulates reactive oxygen species within the cell nucleus.
Academic Article Dual ACE-inhibition and AT1 receptor antagonism improves ventricular lusitropy without affecting cardiac fibrosis in the congenic mRen2.Lewis rat.
Academic Article Neurobiological mechanisms contributing to alcohol-stress-anxiety interactions.
Academic Article Does ACE2 contribute to the development of hypertension?
Academic Article Developmental effect of antenatal exposure to betamethasone on renal angiotensin II activity in the young adult sheep.
Academic Article Inhibition of angiotensin-converting enzyme 2 exacerbates cardiac hypertrophy and fibrosis in Ren-2 hypertensive rats.
Academic Article Angiotensin-(1-7) prevents diabetes-induced attenuation in PPAR-gamma and catalase activities.
Academic Article Influence of estrogen depletion and salt loading on renal angiotensinogen expression in the mRen(2).Lewis strain.
Academic Article Prenatal betamethasone exposure alters renal function in immature sheep: sex differences in effects.
Academic Article Angiotensin-(1-12) requires angiotensin converting enzyme and AT1 receptors for cardiovascular actions within the solitary tract nucleus.
Academic Article Attenuation of salt-induced cardiac remodeling and diastolic dysfunction by the GPER agonist G-1 in female mRen2.Lewis rats.
Academic Article Neuronal nitric oxide synthase inhibition improves diastolic function and reduces oxidative stress in ovariectomized mRen2.Lewis rats.
Academic Article Angiotensin-(1-7) blockade attenuates captopril- or hydralazine-induced cardiovascular protection in spontaneously hypertensive rats treated with NG-nitro-L-arginine methyl ester.
Academic Article Exaggerated sympathetic mediated responses to behavioral or pharmacological challenges following antenatal betamethasone exposure.
Academic Article Angiotensin-converting enzyme inhibition, but not AT(1) receptor blockade, in the solitary tract nucleus improves baroreflex sensitivity in anesthetized transgenic hypertensive (mRen2)27 rats.
Academic Article Novel roles of nuclear angiotensin receptors and signaling mechanisms.
Academic Article Amelioration of renal injury and oxidative stress by the nNOS inhibitor L-VNIO in the salt-sensitive mRen2.Lewis congenic rat.
Academic Article Differential regulation of circulating and renal ACE2 and ACE in hypertensive mRen2.Lewis rats with early-onset diabetes.
Academic Article Divergent pathways for the angiotensin-(1-12) metabolism in the rat circulation and kidney.
Academic Article Differences in oxidative stress status and expression of MKP-1 in dorsal medulla of transgenic rats with altered brain renin-angiotensin system.
Concept Animals, Congenic
Concept Pregnancy, Animal
Concept Models, Animal
Concept Animals
Concept Behavior, Animal
Concept Animals, Genetically Modified
Concept Disease Models, Animal
Concept Animals, Newborn
Concept Animals, Suckling
Academic Article Fetal betamethasone exposure attenuates angiotensin-(1-7)-Mas receptor expression in the dorsal medulla of adult sheep.
Academic Article Reduced vasorelaxation to estradiol and G-1 in aged female and adult male rats is associated with GPR30 downregulation.
Academic Article Characterization of a Moraxella species that causes epistaxis in macaques.
Academic Article Antenatal betamethasone exposure is associated with lower ANG-(1-7) and increased ACE in the CSF of adult sheep.
Academic Article Of diabetic mice and ACE2: a new biomarker of renal disease?
Academic Article Characterization of the cardiac renin angiotensin system in oophorectomized and estrogen-replete mRen2.Lewis rats.
Academic Article Antenatal betamethasone exposure alters renal responses to angiotensin-(1-7) in uninephrectomized adult male sheep.
Academic Article Vasodilation by GPER in mesenteric arteries involves both endothelial nitric oxide and smooth muscle cAMP signaling.
Academic Article Enhanced activity of an angiotensin-(1-7) neuropeptidase in glucocorticoid-induced fetal programming.
Academic Article Role of estrogen in diastolic dysfunction.
Academic Article Evidence for an angiotensin-(1-7) neuropeptidase expressed in the brain medulla and CSF of sheep.
Academic Article The ins and outs of angiotensin processing within the kidney.
Academic Article Sex-specific effect of antenatal betamethasone exposure on renal oxidative stress induced by angiotensins in adult sheep.
Academic Article Angiotensin-(1-7) abolishes AGE-induced cellular hypertrophy and myofibroblast transformation via inhibition of ERK1/2.
Academic Article An angiotensin-(1-7) peptidase in the kidney cortex, proximal tubules, and human HK-2 epithelial cells that is distinct from insulin-degrading enzyme.
Academic Article Antenatal glucocorticoid treatment alters Na+ uptake in renal proximal tubule cells from adult offspring in a sex-specific manner.
Academic Article Nuclear expression of renin-angiotensin system components in NRK-52E renal epithelial cells.
Academic Article Sex-Specific Changes in Renal Angiotensin-Converting Enzyme and Angiotensin-Converting Enzyme 2 Gene Expression and Enzyme Activity at Birth and Over the First Year of Life.
Academic Article Biochemical evaluation of the renin-angiotensin system: the good, bad, and absolute?
Academic Article Reply to "Letter to the editor: Angiotensin quantification by mass spectrometry".
Academic Article GPER activation ameliorates aortic remodeling induced by salt-sensitive hypertension.
Academic Article Twostriped Walkingstick Targets Human Eye With Chemical Defense Spray.
Academic Article Establishment of Early Endpoints in Mouse Total-Body Irradiation Model.
Academic Article Significance of Bioindicators for Early Predictions on Diagnosis and Therapy of Irradiated Minipigs.
Academic Article Measurement of Angiotensin Peptides: HPLC-RIA.
Academic Article Angiotensin-(1-7)-dependent vasorelaxation of the renal artery exhibits unique angiotensin and bradykinin receptor selectivity.
Academic Article Angiotensinogen import in isolated proximal tubules: evidence for mitochondrial trafficking and uptake.
Academic Article Evidence for a mitochondrial angiotensin-(1-7) system in the kidney.
Grant Novel Angiotensin-(1-7) Endopeptidase in Fetal Programming
Academic Article Antenatal betamethasone attenuates the angiotensin-(1-7)-Mas receptor-nitric oxide axis in isolated proximal tubule cells.
Academic Article Assessment of the Renin-Angiotensin System in Cellular Organelle: New Arenas for Study in the Mitochondria.
Academic Article Attenuation of pulmonary ACE2 activity impairs inactivation of des-Arg9 bradykinin/BKB1R axis and facilitates LPS-induced neutrophil infiltration.
Academic Article Sex-dependent expression of brain medullary MAP and PI3 kinases in adult sheep with antenatal betamethasone exposure.
Academic Article Fetal programming and the angiotensin-(1-7) axis: a review of the experimental and clinical data.
Academic Article Central ANG-(1-7) infusion improves blood pressure regulation in antenatal betamethasone-exposed sheep and reveals sex-dependent effects on oxidative stress.
Academic Article Comparison of Candesartan and Angiotensin-(1-7) Combination to Mito-TEMPO Treatment for Normalizing Blood Pressure and Sympathovagal Balance in (mREN2)27 Rats.

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