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One or more keywords matched the following properties of Lockhart, Samuel
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overview Samuel N. Lockhart, Ph.D., is a neuroscientist who has spent his research career disentangling normal brain aging from preclinical disease. He earned his Ph.D. in Neuroscience from UC Davis with Dr. Charles DeCarli, investigating the impacts of age and cerebrovascular disease on brain function and cognition, and completed a postdoctoral fellowship with Dr. William Jagust at UC Berkeley, examining how tau and amyloid accumulation affect brain structure and cognitive trajectories. He is an author of publications that have appeared in Neuron, NeuroImage, Neurology, Journal of Neuroscience, Brain, Stroke, Journal of Nuclear Medicine, and JAMA Neurology, among others. At Wake Forest, Dr. Lockhart is an Associate Professor of Internal Medicine and Gerontology and Geriatric Medicine. He plans to build a research program in multimodal neuroimaging and cognitive analyses of aging and diseases of aging, with a focus on interactions between metabolic dysfunction and vascular and degenerative pathology.
One or more keywords matched the following items that are connected to Lockhart, Samuel
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Concept tau Proteins
Concept Tauopathies
Academic Article Tau and ß-Amyloid Are Associated with Medial Temporal Lobe Structure, Function, and Memory Encoding in Normal Aging.
Academic Article Amyloid and tau PET demonstrate region-specific associations in normal older people.
Academic Article Dynamic PET Measures of Tau Accumulation in Cognitively Normal Older Adults and Alzheimer's Disease Patients Measured Using [18F] THK-5351.
Academic Article Comparison of multiple tau-PET measures as biomarkers in aging and Alzheimer's disease.
Academic Article Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer's disease.
Academic Article PET Imaging of Tau Deposition in the Aging Human Brain.
Academic Article Reference Tissue-Based Kinetic Evaluation of 18F-AV-1451 for Tau Imaging.
Academic Article Local and distant relationships between amyloid, tau and neurodegeneration in Alzheimer's Disease.
Academic Article Entorhinal Tau Pathology, Episodic Memory Decline, and Neurodegeneration in Aging.
Academic Article Subthreshold Amyloid Predicts Tau Deposition in Aging.
Academic Article Relationships Between Tau and Glucose Metabolism Reflect Alzheimer's Disease Pathology in Cognitively Normal Older Adults.
Academic Article Scan-Time Corrections for 80-100-min Standardizetd Uptake Volume Ratios to Measure the 18F-AV-1451 Tracer for Tau Imaging.
Grant Biomarkers of preclinical Alzheimer disease and cognition
Academic Article Prediction of fast decline in amyloid positive mild cognitive impairment patients using multimodal biomarkers.
Academic Article Application of an amyloid and tau classification system in subcortical vascular cognitive impairment patients.
Academic Article CSF glucose tracks regional tau progression based on Alzheimer's disease risk factors.
Academic Article Optimizing quantification of MK6240 tau PET in unimpaired older adults.
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  • Tau