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Targeting defective DNA repair for the prevention of BRCA1-associated cancers
Grant
Why?
Enhanced sensitivity to cisplatin and gemcitabine in Brca1-deficient murine mammary epithelial cells.
Academic Article
Why?
Therapeutic targeting of BRCA1-mutated breast cancers with agents that activate DNA repair.
Academic Article
Why?
Hot Spot Analysis of the Breast Cancer Susceptibility Protein
Grant
Why?
BRCA1: Beyond double-strand break repair.
Academic Article
Why?
Correcting errors in the BRCA1 warning system.
Academic Article
Why?
Inactivation of BRCA1 and BRCA2 in ovarian cancer.
Academic Article
Why?
Modulation of aromatase expression by BRCA1: a possible link to tissue-specific tumor suppression.
Academic Article
Why?
Multi-scale imaging of breast cancer proteins during DNA repair
Grant
Why?
BRCA1: a movement toward cancer prevention.
Academic Article
Why?
Genetic and clinical landscape of breast cancers with germline BRCA1/2 variants.
Academic Article
Why?
Mastectomy or Breast-Conserving Therapy for BRCA1/2 Variant Carriers.
Academic Article
Why?
BRCA1 Protein
Concept
Why?
Genes, BRCA1
Concept
Why?
Allele imbalance, or loss of heterozygosity, in normal breast epithelium of sporadic breast cancer cases and BRCA1 gene mutation carriers is increased compared with reduction mammoplasty tissues.
Academic Article
Why?
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