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The TREX1 exonuclease R114H mutation in Aicardi-Goutières syndrome and lupus reveals dimeric structure requirements for DNA degradation activity.
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has major subject area list Autoimmune Diseases of the Nervous System; DNA, Single-Stranded; Exodeoxyribonucleases; Lupus Erythematosus, Systemic; Mutation, Missense; Nervous System Malformations; Phosphoproteins; Protein Multimerization
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  • Protein Multimerization