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Connection

Mei-Chuan Ko to Analgesics, Opioid

This is a "connection" page, showing publications Mei-Chuan Ko has written about Analgesics, Opioid.
Connection Strength

8.549
  1. Ding H, Kiguchi N, Mabry KM, Kishioka S, Ko MC. Functional consequences of short-term exposure to opioids versus cannabinoids in nonhuman primates. Neuropharmacology. 2023 Feb 01; 223:109328.
    View in: PubMed
    Score: 0.725
  2. Kiguchi N, Ko MC. Potential therapeutic targets for the treatment of opioid abuse and pain. Adv Pharmacol. 2022; 93:335-371.
    View in: PubMed
    Score: 0.677
  3. Kiguchi N, Kishioka S, Ko MC. [Therapeutic potentials of safe opioid analgesics targeting nociceptin/orphanin FQ peptide receptor]. Nihon Yakurigaku Zasshi. 2021; 156(3):139-144.
    View in: PubMed
    Score: 0.638
  4. Kiguchi N, Ding H, Cami-Kobeci G, Sukhtankar DD, Czoty PW, DeLoid HB, Hsu FC, Toll L, Husbands SM, Ko MC. BU10038 as a safe opioid analgesic with fewer side-effects after systemic and intrathecal administration in primates. Br J Anaesth. 2019 Jun; 122(6):e146-e156.
    View in: PubMed
    Score: 0.561
  5. Kiguchi N, Ko MC. Effects of NOP-Related Ligands in Nonhuman Primates. Handb Exp Pharmacol. 2019; 254:323-343.
    View in: PubMed
    Score: 0.555
  6. Ding H, Kiguchi N, Yasuda D, Daga PR, Polgar WE, Lu JJ, Czoty PW, Kishioka S, Zaveri NT, Ko MC. A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primates. Sci Transl Med. 2018 08 29; 10(456).
    View in: PubMed
    Score: 0.542
  7. Ding H, Czoty PW, Kiguchi N, Cami-Kobeci G, Sukhtankar DD, Nader MA, Husbands SM, Ko MC. A novel orvinol analog, BU08028, as a safe opioid analgesic without abuse liability in primates. Proc Natl Acad Sci U S A. 2016 09 13; 113(37):E5511-8.
    View in: PubMed
    Score: 0.472
  8. Lee H, Ko MC. Distinct functions of opioid-related peptides and gastrin-releasing peptide in regulating itch and pain in the spinal cord of primates. Sci Rep. 2015 Jun 29; 5:11676.
    View in: PubMed
    Score: 0.435
  9. Ko MC. Neuraxial opioid-induced itch and its pharmacological antagonism. Handb Exp Pharmacol. 2015; 226:315-35.
    View in: PubMed
    Score: 0.421
  10. Sukhtankar DD, Lee H, Rice KC, Ko MC. Differential effects of opioid-related ligands and NSAIDs in nonhuman primate models of acute and inflammatory pain. Psychopharmacology (Berl). 2014 Apr; 231(7):1377-87.
    View in: PubMed
    Score: 0.389
  11. Sukhtankar DD, Zaveri NT, Husbands SM, Ko MC. Effects of spinally administered bifunctional nociceptin/orphanin FQ peptide receptor/ยต-opioid receptor ligands in mouse models of neuropathic and inflammatory pain. J Pharmacol Exp Ther. 2013 Jul; 346(1):11-22.
    View in: PubMed
    Score: 0.375
  12. Ko MC, Woods JH, Fantegrossi WE, Galuska CM, Wichmann J, Prinssen EP. Behavioral effects of a synthetic agonist selective for nociceptin/orphanin FQ peptide receptors in monkeys. Neuropsychopharmacology. 2009 Aug; 34(9):2088-96.
    View in: PubMed
    Score: 0.281
  13. Xie H, Woods JH, Traynor JR, Ko MC. The spinal antinociceptive effects of endomorphins in rats: behavioral and G protein functional studies. Anesth Analg. 2008 Jun; 106(6):1873-81.
    View in: PubMed
    Score: 0.267
  14. Pascoe JE, Williams KL, Mukhopadhyay P, Rice KC, Woods JH, Ko MC. Effects of mu, kappa, and delta opioid receptor agonists on the function of hypothalamic-pituitary-adrenal axis in monkeys. Psychoneuroendocrinology. 2008 May; 33(4):478-86.
    View in: PubMed
    Score: 0.262
  15. Lee H, Naughton NN, Woods JH, Ko MC. Effects of butorphanol on morphine-induced itch and analgesia in primates. Anesthesiology. 2007 Sep; 107(3):478-85.
    View in: PubMed
    Score: 0.253
  16. Ko MC, Song MS, Edwards T, Lee H, Naughton NN. The role of central mu opioid receptors in opioid-induced itch in primates. J Pharmacol Exp Ther. 2004 Jul; 310(1):169-76.
    View in: PubMed
    Score: 0.199
  17. Lee H, Naughton NN, Woods JH, Ko MC. Characterization of scratching responses in rats following centrally administered morphine or bombesin. Behav Pharmacol. 2003 Nov; 14(7):501-8.
    View in: PubMed
    Score: 0.194
  18. Ding H, Kiguchi N, Dobbins M, Romero-Sandoval EA, Kishioka S, Ko MC. Nociceptin Receptor-Related Agonists as Safe and Non-addictive Analgesics. Drugs. 2023 Jun; 83(9):771-793.
    View in: PubMed
    Score: 0.188
  19. Ko MC, Terner J, Hursh S, Woods JH, Winger G. Relative reinforcing effects of three opioids with different durations of action. J Pharmacol Exp Ther. 2002 May; 301(2):698-704.
    View in: PubMed
    Score: 0.175
  20. Chen CM, Ding H, Mabry KM, Ko MC. Enhanced antidepressant-like effects of a delta opioid receptor agonist, SNC80, in rats under inflammatory pain. Pharmacol Biochem Behav. 2022 Mar; 214:173341.
    View in: PubMed
    Score: 0.172
  21. Ko MC, Naughton NN. An experimental itch model in monkeys: characterization of intrathecal morphine-induced scratching and antinociception. Anesthesiology. 2000 Mar; 92(3):795-805.
    View in: PubMed
    Score: 0.150
  22. Ko MC, Johnson MD, Butelman ER, Willmont KJ, Mosberg HI, Woods JH. Intracisternal nor-binaltorphimine distinguishes central and peripheral kappa-opioid antinociception in rhesus monkeys. J Pharmacol Exp Ther. 1999 Dec; 291(3):1113-20.
    View in: PubMed
    Score: 0.148
  23. Ko MC, Butelman ER, Traynor JR, Woods JH. Differentiation of kappa opioid agonist-induced antinociception by naltrexone apparent pA2 analysis in rhesus monkeys. J Pharmacol Exp Ther. 1998 May; 285(2):518-26.
    View in: PubMed
    Score: 0.132
  24. Lin AP, Ko MC. The therapeutic potential of nociceptin/orphanin FQ receptor agonists as analgesics without abuse liability. ACS Chem Neurosci. 2013 Feb 20; 4(2):214-24.
    View in: PubMed
    Score: 0.091
  25. Ko MC, Naughton NN. Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys. J Pain. 2009 May; 10(5):509-16.
    View in: PubMed
    Score: 0.070
  26. Zhang H, Torregrossa MM, Jutkiewicz EM, Shi YG, Rice KC, Woods JH, Watson SJ, Ko MC. Endogenous opioids upregulate brain-derived neurotrophic factor mRNA through delta- and micro-opioid receptors independent of antidepressant-like effects. Eur J Neurosci. 2006 Feb; 23(4):984-94.
    View in: PubMed
    Score: 0.057
  27. Kishioka S, Ko MC, Woods JH. Diltiazem enhances the analgesic but not the respiratory depressant effects of morphine in rhesus monkeys. Eur J Pharmacol. 2000 May 26; 397(1):85-92.
    View in: PubMed
    Score: 0.038
  28. Ko MC, Tuchman JE, Johnson MD, Wiesenauer K, Woods JH. Local administration of mu or kappa opioid agonists attenuates capsaicin-induced thermal hyperalgesia via peripheral opioid receptors in rats. Psychopharmacology (Berl). 2000 Feb; 148(2):180-5.
    View in: PubMed
    Score: 0.037
  29. Butelman ER, Ko MC, Sobczyk-Kojiro K, Mosberg HI, Van Bemmel B, Zernig G, Woods JH. kappa-Opioid receptor binding populations in rhesus monkey brain: relationship to an assay of thermal antinociception. J Pharmacol Exp Ther. 1998 May; 285(2):595-601.
    View in: PubMed
    Score: 0.033
  30. Butelman ER, Ko MC, Traynor JR, Vivian JA, Kreek MJ, Woods JH. GR89,696: a potent kappa-opioid agonist with subtype selectivity in rhesus monkeys. J Pharmacol Exp Ther. 2001 Sep; 298(3):1049-59.
    View in: PubMed
    Score: 0.010
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.