Mei-Chuan Ko to Animals
This is a "connection" page, showing publications Mei-Chuan Ko has written about Animals.
Connection Strength
2.942
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Ding H, Kiguchi N, Dobbins M, Romero-Sandoval EA, Kishioka S, Ko MC. Nociceptin Receptor-Related Agonists as Safe and Non-addictive Analgesics. Drugs. 2023 Jun; 83(9):771-793.
Score: 0.099
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Ding H, Kiguchi N, Mabry KM, Kishioka S, Ko MC. Functional consequences of short-term exposure to opioids versus cannabinoids in nonhuman primates. Neuropharmacology. 2023 Feb 01; 223:109328.
Score: 0.096
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Chen CM, Ding H, Mabry KM, Ko MC. Enhanced antidepressant-like effects of a delta opioid receptor agonist, SNC80, in rats under inflammatory pain. Pharmacol Biochem Behav. 2022 Mar; 214:173341.
Score: 0.091
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Kiguchi N, Ko MC. Potential therapeutic targets for the treatment of opioid abuse and pain. Adv Pharmacol. 2022; 93:335-371.
Score: 0.089
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Kiguchi N, Kishioka S, Ko MC. [Therapeutic potentials of safe opioid analgesics targeting nociceptin/orphanin FQ peptide receptor]. Nihon Yakurigaku Zasshi. 2021; 156(3):139-144.
Score: 0.084
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Ding H, Kiguchi N, Perrey DA, Nguyen T, Czoty PW, Hsu FC, Zhang Y, Ko MC. Antinociceptive, reinforcing, and pruritic effects of the G-protein signalling-biased mu opioid receptor agonist PZM21 in non-human primates. Br J Anaesth. 2020 10; 125(4):596-604.
Score: 0.082
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Kiguchi N, Ding H, Cami-Kobeci G, Sukhtankar DD, Czoty PW, DeLoid HB, Hsu FC, Toll L, Husbands SM, Ko MC. BU10038 as a safe opioid analgesic with fewer side-effects after systemic and intrathecal administration in primates. Br J Anaesth. 2019 Jun; 122(6):e146-e156.
Score: 0.074
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Kiguchi N, Ko MC. Effects of NOP-Related Ligands in Nonhuman Primates. Handb Exp Pharmacol. 2019; 254:323-343.
Score: 0.073
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Ding H, Kiguchi N, Yasuda D, Daga PR, Polgar WE, Lu JJ, Czoty PW, Kishioka S, Zaveri NT, Ko MC. A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primates. Sci Transl Med. 2018 08 29; 10(456).
Score: 0.072
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Ding H, Kiguchi N, Kishioka S, Ma T, Peters CM, Ko MC. Differential mRNA expression of neuroinflammatory modulators in the spinal cord and thalamus of type 2 diabetic monkeys. J Diabetes. 2018 Nov; 10(11):886-895.
Score: 0.071
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Kiguchi N, Ding H, Peters CM, Kock ND, Kishioka S, Cline JM, Wagner JD, Ko MC. Altered expression of glial markers, chemokines, and opioid receptors in the spinal cord of type 2 diabetic monkeys. Biochim Biophys Acta Mol Basis Dis. 2017 01; 1863(1):274-283.
Score: 0.063
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Ding H, Czoty PW, Kiguchi N, Cami-Kobeci G, Sukhtankar DD, Nader MA, Husbands SM, Ko MC. A novel orvinol analog, BU08028, as a safe opioid analgesic without abuse liability in primates. Proc Natl Acad Sci U S A. 2016 09 13; 113(37):E5511-8.
Score: 0.062
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Kiguchi N, Ding H, Ko MC. Central N/OFQ-NOP Receptor System in Pain Modulation. Adv Pharmacol. 2016; 75:217-43.
Score: 0.059
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Kiguchi N, Sukhtankar DD, Ding H, Tanaka K, Kishioka S, Peters CM, Ko MC. Spinal Functions of B-Type Natriuretic Peptide, Gastrin-Releasing Peptide, and Their Cognate Receptors for Regulating Itch in Mice. J Pharmacol Exp Ther. 2016 Mar; 356(3):596-603.
Score: 0.059
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Lee H, Ko MC. Distinct functions of opioid-related peptides and gastrin-releasing peptide in regulating itch and pain in the spinal cord of primates. Sci Rep. 2015 Jun 29; 5:11676.
Score: 0.058
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Rizzi A, Sukhtankar DD, Ding H, Hayashida K, Ruzza C, Guerrini R, Calò G, Ko MC. Spinal antinociceptive effects of the novel NOP receptor agonist PWT2-nociceptin/orphanin FQ in mice and monkeys. Br J Pharmacol. 2015 Jul; 172(14):3661-70.
Score: 0.057
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Ding H, Hayashida K, Suto T, Sukhtankar DD, Kimura M, Mendenhall V, Ko MC. Supraspinal actions of nociceptin/orphanin FQ, morphine and substance P in regulating pain and itch in non-human primates. Br J Pharmacol. 2015 Jul; 172(13):3302-12.
Score: 0.057
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Ko MC. Neuraxial opioid-induced itch and its pharmacological antagonism. Handb Exp Pharmacol. 2015; 226:315-35.
Score: 0.056
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Sukhtankar DD, Lagorio CH, Ko MC. Effects of the NOP agonist SCH221510 on producing and attenuating reinforcing effects as measured by drug self-administration in rats. Eur J Pharmacol. 2014 Dec 15; 745:182-9.
Score: 0.055
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Sukhtankar DD, Lee H, Rice KC, Ko MC. Differential effects of opioid-related ligands and NSAIDs in nonhuman primate models of acute and inflammatory pain. Psychopharmacology (Berl). 2014 Apr; 231(7):1377-87.
Score: 0.051
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Sukhtankar DD, Ko MC. Physiological function of gastrin-releasing peptide and neuromedin B receptors in regulating itch scratching behavior in the spinal cord of mice. PLoS One. 2013; 8(6):e67422.
Score: 0.050
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Sukhtankar DD, Zaveri NT, Husbands SM, Ko MC. Effects of spinally administered bifunctional nociceptin/orphanin FQ peptide receptor/µ-opioid receptor ligands in mouse models of neuropathic and inflammatory pain. J Pharmacol Exp Ther. 2013 Jul; 346(1):11-22.
Score: 0.050
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Lin AP, Ko MC. The therapeutic potential of nociceptin/orphanin FQ receptor agonists as analgesics without abuse liability. ACS Chem Neurosci. 2013 Feb 20; 4(2):214-24.
Score: 0.048
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Cremeans CM, Gruley E, Kyle DJ, Ko MC. Roles of µ-opioid receptors and nociceptin/orphanin FQ peptide receptors in buprenorphine-induced physiological responses in primates. J Pharmacol Exp Ther. 2012 Oct; 343(1):72-81.
Score: 0.047
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Collins GT, Brim RL, Noon KR, Narasimhan D, Lukacs NW, Sunahara RK, Woods JH, Ko MC. Repeated administration of a mutant cocaine esterase: effects on plasma cocaine levels, cocaine-induced cardiovascular activity, and immune responses in rhesus monkeys. J Pharmacol Exp Ther. 2012 Jul; 342(1):205-13.
Score: 0.046
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Su PY, Ko MC. The role of central gastrin-releasing peptide and neuromedin B receptors in the modulation of scratching behavior in rats. J Pharmacol Exp Ther. 2011 Jun; 337(3):822-9.
Score: 0.043
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Collins GT, Carey KA, Narasimhan D, Nichols J, Berlin AA, Lukacs NW, Sunahara RK, Woods JH, Ko MC. Amelioration of the cardiovascular effects of cocaine in rhesus monkeys by a long-acting mutant form of cocaine esterase. Neuropsychopharmacology. 2011 Apr; 36(5):1047-59.
Score: 0.042
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Hu E, Calò G, Guerrini R, Ko MC. Long-lasting antinociceptive spinal effects in primates of the novel nociceptin/orphanin FQ receptor agonist UFP-112. Pain. 2010 Jan; 148(1):107-113.
Score: 0.039
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Zhang HN, Ko MC. Seizure activity involved in the up-regulation of BDNF mRNA expression by activation of central mu opioid receptors. Neuroscience. 2009 Jun 16; 161(1):301-10.
Score: 0.037
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Ko MC, Woods JH, Fantegrossi WE, Galuska CM, Wichmann J, Prinssen EP. Behavioral effects of a synthetic agonist selective for nociceptin/orphanin FQ peptide receptors in monkeys. Neuropsychopharmacology. 2009 Aug; 34(9):2088-96.
Score: 0.037
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Ko MC, Naughton NN. Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys. J Pain. 2009 May; 10(5):509-16.
Score: 0.037
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Ko MC, Narasimhan D, Berlin AA, Lukacs NW, Sunahara RK, Woods JH. Effects of cocaine esterase following its repeated administration with cocaine in mice. Drug Alcohol Depend. 2009 May 01; 101(3):202-9.
Score: 0.037
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Ko MC, Husbands SM. Effects of atypical kappa-opioid receptor agonists on intrathecal morphine-induced itch and analgesia in primates. J Pharmacol Exp Ther. 2009 Jan; 328(1):193-200.
Score: 0.036
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Xie H, Woods JH, Traynor JR, Ko MC. The spinal antinociceptive effects of endomorphins in rats: behavioral and G protein functional studies. Anesth Analg. 2008 Jun; 106(6):1873-81.
Score: 0.035
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Pascoe JE, Williams KL, Mukhopadhyay P, Rice KC, Woods JH, Ko MC. Effects of mu, kappa, and delta opioid receptor agonists on the function of hypothalamic-pituitary-adrenal axis in monkeys. Psychoneuroendocrinology. 2008 May; 33(4):478-86.
Score: 0.035
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Lee H, Naughton NN, Woods JH, Ko MC. Effects of butorphanol on morphine-induced itch and analgesia in primates. Anesthesiology. 2007 Sep; 107(3):478-85.
Score: 0.033
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Zhang H, Shi YG, Woods JH, Watson SJ, Ko MC. Central kappa-opioid receptor-mediated antidepressant-like effects of nor-Binaltorphimine: behavioral and BDNF mRNA expression studies. Eur J Pharmacol. 2007 Sep 10; 570(1-3):89-96.
Score: 0.033
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Ko MC, Bowen LD, Narasimhan D, Berlin AA, Lukacs NW, Sunahara RK, Cooper ZD, Woods JH. Cocaine esterase: interactions with cocaine and immune responses in mice. J Pharmacol Exp Ther. 2007 Feb; 320(2):926-33.
Score: 0.032
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Ko MC, Wei H, Woods JH, Kennedy RT. Effects of intrathecally administered nociceptin/orphanin FQ in monkeys: behavioral and mass spectrometric studies. J Pharmacol Exp Ther. 2006 Sep; 318(3):1257-64.
Score: 0.031
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Zhang H, Torregrossa MM, Jutkiewicz EM, Shi YG, Rice KC, Woods JH, Watson SJ, Ko MC. Endogenous opioids upregulate brain-derived neurotrophic factor mRNA through delta- and micro-opioid receptors independent of antidepressant-like effects. Eur J Neurosci. 2006 Feb; 23(4):984-94.
Score: 0.030
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Ko MC, Divin MF, Lee H, Woods JH, Traynor JR. Differential in vivo potencies of naltrexone and 6beta-naltrexol in the monkey. J Pharmacol Exp Ther. 2006 Feb; 316(2):772-9.
Score: 0.029
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Ko MC, Song MS, Edwards T, Lee H, Naughton NN. The role of central mu opioid receptors in opioid-induced itch in primates. J Pharmacol Exp Ther. 2004 Jul; 310(1):169-76.
Score: 0.026
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Lee H, Naughton NN, Woods JH, Ko MC. Characterization of scratching responses in rats following centrally administered morphine or bombesin. Behav Pharmacol. 2003 Nov; 14(7):501-8.
Score: 0.026
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Ko MC, Willmont KJ, Lee H, Flory GS, Woods JH. Ultra-long antagonism of kappa opioid agonist-induced diuresis by intracisternal nor-binaltorphimine in monkeys. Brain Res. 2003 Aug 22; 982(1):38-44.
Score: 0.025
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Ko MC, Lee H, Harrison C, Clark MJ, Song HF, Naughton NN, Woods JH, Traynor JR. Studies of micro-, kappa-, and delta-opioid receptor density and G protein activation in the cortex and thalamus of monkeys. J Pharmacol Exp Ther. 2003 Jul; 306(1):179-86.
Score: 0.025
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Ko MC, Lee H, Song MS, Sobczyk-Kojiro K, Mosberg HI, Kishioka S, Woods JH, Naughton NN. Activation of kappa-opioid receptors inhibits pruritus evoked by subcutaneous or intrathecal administration of morphine in monkeys. J Pharmacol Exp Ther. 2003 Apr; 305(1):173-9.
Score: 0.025
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Ko MC, Terner J, Hursh S, Woods JH, Winger G. Relative reinforcing effects of three opioids with different durations of action. J Pharmacol Exp Ther. 2002 May; 301(2):698-704.
Score: 0.023
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Ko MC, Naughton NN, Traynor JR, Song MS, Woods JH, Rice KC, McKnight AT. Orphanin FQ inhibits capsaicin-induced thermal nociception in monkeys by activation of peripheral ORL1 receptors. Br J Pharmacol. 2002 Feb; 135(4):943-50.
Score: 0.023
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Jester HM, Gosrani SP, Ding H, Zhou X, Ko MC, Ma T. Characterization of Early Alzheimer's Disease-Like Pathological Alterations in Non-Human Primates with Aging: A Pilot Study. J Alzheimers Dis. 2022; 88(3):957-970.
Score: 0.023
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Luo X, Chen O, Wang Z, Bang S, Ji J, Lee SH, Huh Y, Furutani K, He Q, Tao X, Ko MC, Bortsov A, Donnelly CR, Chen Y, Nackley A, Berta T, Ji RR. IL-23/IL-17A/TRPV1 axis produces mechanical pain via macrophage-sensory neuron crosstalk in female mice. Neuron. 2021 Sep 01; 109(17):2691-2706.e5.
Score: 0.022
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Donnelly CR, Jiang C, Andriessen AS, Wang K, Wang Z, Ding H, Zhao J, Luo X, Lee MS, Lei YL, Maixner W, Ko MC, Ji RR. STING controls nociception via type I interferon signalling in sensory neurons. Nature. 2021 03; 591(7849):275-280.
Score: 0.021
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Ko MC, Willmont KJ, Burritt A, Hruby VJ, Woods JH. Local inhibitory effects of dynorphin A-(1-17) on capsaicin-induced thermal allodynia in rhesus monkeys. Eur J Pharmacol. 2000 Aug 18; 402(1-2):69-76.
Score: 0.021
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Mishra SK, Wheeler JJ, Pitake S, Ding H, Jiang C, Fukuyama T, Paps JS, Ralph P, Coyne J, Parkington M, DeBrecht J, Ehrhardt-Humbert LC, Cruse GP, Bäumer W, Ji RR, Ko MC, Olivry T. Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch. Cell Rep. 2020 04 07; 31(1):107472.
Score: 0.020
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Kiguchi N, Uta D, Ding H, Uchida H, Saika F, Matsuzaki S, Fukazawa Y, Abe M, Sakimura K, Ko MC, Kishioka S. GRP receptor and AMPA receptor cooperatively regulate itch-responsive neurons in the spinal dorsal horn. Neuropharmacology. 2020 06 15; 170:108025.
Score: 0.020
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Ko MC, Naughton NN. An experimental itch model in monkeys: characterization of intrathecal morphine-induced scratching and antinociception. Anesthesiology. 2000 Mar; 92(3):795-805.
Score: 0.020
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Ko MC, Tuchman JE, Johnson MD, Wiesenauer K, Woods JH. Local administration of mu or kappa opioid agonists attenuates capsaicin-induced thermal hyperalgesia via peripheral opioid receptors in rats. Psychopharmacology (Berl). 2000 Feb; 148(2):180-5.
Score: 0.020
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Ko MC, Johnson MD, Butelman ER, Willmont KJ, Mosberg HI, Woods JH. Intracisternal nor-binaltorphimine distinguishes central and peripheral kappa-opioid antinociception in rhesus monkeys. J Pharmacol Exp Ther. 1999 Dec; 291(3):1113-20.
Score: 0.020
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Ehling S, Fukuyama T, Ko MC, Olivry T, Bäumer W. Neuromedin B Induces Acute Itch in Mice via the Activation of Peripheral Sensory Neurons. Acta Derm Venereol. 2019 May 01; 99(6):587-893.
Score: 0.019
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Flynn SM, Epperly PM, Davenport AT, Cami-Kobeci G, Husbands SM, Ko MC, Czoty PW. Effects of stimulation of mu opioid and nociceptin/orphanin FQ peptide (NOP) receptors on alcohol drinking in rhesus monkeys. Neuropsychopharmacology. 2019 07; 44(8):1476-1484.
Score: 0.019
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Ko MC, Butelman ER, Woods JH. Activation of peripheral kappa opioid receptors inhibits capsaicin-induced thermal nociception in rhesus monkeys. J Pharmacol Exp Ther. 1999 Apr; 289(1):378-85.
Score: 0.019
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Ko MC, Woods JH. Local administration of delta9-tetrahydrocannabinol attenuates capsaicin-induced thermal nociception in rhesus monkeys: a peripheral cannabinoid action. Psychopharmacology (Berl). 1999 Apr; 143(3):322-6.
Score: 0.019
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Ko MC, Butelman ER, Woods JH. The role of peripheral mu opioid receptors in the modulation of capsaicin-induced thermal nociception in rhesus monkeys. J Pharmacol Exp Ther. 1998 Jul; 286(1):150-6.
Score: 0.018
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Ko MC, Butelman ER, Traynor JR, Woods JH. Differentiation of kappa opioid agonist-induced antinociception by naltrexone apparent pA2 analysis in rhesus monkeys. J Pharmacol Exp Ther. 1998 May; 285(2):518-26.
Score: 0.018
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Divin MF, Holden Ko MC, Traynor JR. Comparison of the opioid receptor antagonist properties of naltrexone and 6 beta-naltrexol in morphine-naïve and morphine-dependent mice. Eur J Pharmacol. 2008 Mar 31; 583(1):48-55.
Score: 0.017
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Cerlesi MC, Ding H, Bird MF, Kiguchi N, Ferrari F, Malfacini D, Rizzi A, Ruzza C, Lambert DG, Ko MC, Calo G, Guerrini R. Pharmacological studies on the NOP and opioid receptor agonist PWT2-[Dmt1]N/OFQ(1-13). Eur J Pharmacol. 2017 Jan 05; 794:115-126.
Score: 0.016
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Kiguchi N, Saika F, Kobayashi Y, Ko MC, Kishioka S. TC-2559, an a4ß2 nicotinic acetylcholine receptor agonist, suppresses the expression of CCL3 and IL-1ß through STAT3 inhibition in cultured murine macrophages. J Pharmacol Sci. 2015 Jun; 128(2):83-6.
Score: 0.014
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Liao RM, Ko MC. Chronic effects of haloperidol and SCH23390 on operant and licking behaviors in the rat. Chin J Physiol. 1995; 38(2):65-73.
Score: 0.014
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Schröder W, Lambert DG, Ko MC, Koch T. Functional plasticity of the N/OFQ-NOP receptor system determines analgesic properties of NOP receptor agonists. Br J Pharmacol. 2014 Aug; 171(16):3777-800.
Score: 0.014
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Kishioka S, Kiguchi N, Kobayashi Y, Yamamoto C, Saika F, Wakida N, Ko MC, Woods JH. Pharmacokinetic evidence for the long-lasting effect of nor-binaltorphimine, a potent kappa opioid receptor antagonist, in mice. Neurosci Lett. 2013 Sep 27; 552:98-102.
Score: 0.013
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Molinari S, Camarda V, Rizzi A, Marzola G, Salvadori S, Marzola E, Molinari P, McDonald J, Ko MC, Lambert DG, Calo' G, Guerrini R. [Dmt1]N/OFQ(1-13)-NH2: a potent nociceptin/orphanin FQ and opioid receptor universal agonist. Br J Pharmacol. 2013 Jan; 168(1):151-62.
Score: 0.012
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Collins GT, Narasimhan D, Cunningham AR, Zaks ME, Nichols J, Ko MC, Sunahara RK, Woods JH. Long-lasting effects of a PEGylated mutant cocaine esterase (CocE) on the reinforcing and discriminative stimulus effects of cocaine in rats. Neuropsychopharmacology. 2012 Apr; 37(5):1092-103.
Score: 0.011
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Brim RL, Noon KR, Collins GT, Stein A, Nichols J, Narasimhan D, Ko MC, Woods JH, Sunahara RK. The fate of bacterial cocaine esterase (CocE): an in vivo study of CocE-mediated cocaine hydrolysis, CocE pharmacokinetics, and CocE elimination. J Pharmacol Exp Ther. 2012 Jan; 340(1):83-95.
Score: 0.011
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Narasimhan D, Collins GT, Nance MR, Nichols J, Edwald E, Chan J, Ko MC, Woods JH, Tesmer JJ, Sunahara RK. Subunit stabilization and polyethylene glycolation of cocaine esterase improves in vivo residence time. Mol Pharmacol. 2011 Dec; 80(6):1056-65.
Score: 0.011
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Collins GT, Zaks ME, Cunningham AR, St Clair C, Nichols J, Narasimhan D, Ko MC, Sunahara RK, Woods JH. Effects of a long-acting mutant bacterial cocaine esterase on acute cocaine toxicity in rats. Drug Alcohol Depend. 2011 Nov 01; 118(2-3):158-65.
Score: 0.011
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Xue L, Ko MC, Tong M, Yang W, Hou S, Fang L, Liu J, Zheng F, Woods JH, Tai HH, Zhan CG. Design, preparation, and characterization of high-activity mutants of human butyrylcholinesterase specific for detoxification of cocaine. Mol Pharmacol. 2011 Feb; 79(2):290-7.
Score: 0.010
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Podlesnik CA, Ko MC, Winger G, Wichmann J, Prinssen EP, Woods JH. The effects of nociceptin/orphanin FQ receptor agonist Ro 64-6198 and diazepam on antinociception and remifentanil self-administration in rhesus monkeys. Psychopharmacology (Berl). 2011 Jan; 213(1):53-60.
Score: 0.010
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Park JB, Kwon YM, Lee TY, Brim R, Ko MC, Sunahara RK, Woods JH, Yang VC. PEGylation of bacterial cocaine esterase for protection against protease digestion and immunogenicity. J Control Release. 2010 Mar 03; 142(2):174-9.
Score: 0.010
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Collins GT, Brim RL, Narasimhan D, Ko MC, Sunahara RK, Zhan CG, Woods JH. Cocaine esterase prevents cocaine-induced toxicity and the ongoing intravenous self-administration of cocaine in rats. J Pharmacol Exp Ther. 2009 Nov; 331(2):445-55.
Score: 0.010
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Gao D, Narasimhan DL, Macdonald J, Brim R, Ko MC, Landry DW, Woods JH, Sunahara RK, Zhan CG. Thermostable variants of cocaine esterase for long-time protection against cocaine toxicity. Mol Pharmacol. 2009 Feb; 75(2):318-23.
Score: 0.009
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Zheng F, Yang W, Ko MC, Liu J, Cho H, Gao D, Tong M, Tai HH, Woods JH, Zhan CG. Most efficient cocaine hydrolase designed by virtual screening of transition states. J Am Chem Soc. 2008 Sep 10; 130(36):12148-55.
Score: 0.009
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Meier TR, Myers DD, Eaton KA, Ko MH, Hankenson FC. Gangrenous Clostridium perfringens infection and subsequent wound management in a rhesus macaque (Macaca mulatta). J Am Assoc Lab Anim Sci. 2007 Jul; 46(4):68-73.
Score: 0.008
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Hawkinson JE, Szoke BG, Garofalo AW, Hom DS, Zhang H, Dreyer M, Fukuda JY, Chen L, Samant B, Simmonds S, Zeitz KP, Wadsworth A, Liao A, Chavez RA, Zmolek W, Ruslim L, Bova MP, Holcomb R, Butelman ER, Ko MC, Malmberg AB. Pharmacological, pharmacokinetic, and primate analgesic efficacy profile of the novel bradykinin B1 Receptor antagonist ELN441958. J Pharmacol Exp Ther. 2007 Aug; 322(2):619-30.
Score: 0.008
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Fantegrossi WE, Ko MC, Woods JH, Richelson E. Antinociceptive, hypothermic, hypotensive, and reinforcing effects of a novel neurotensin receptor agonist, NT69L, in rhesus monkeys. Pharmacol Biochem Behav. 2005 Feb; 80(2):341-9.
Score: 0.007
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Neilan CL, Husbands SM, Breeden S, Ko MC, Aceto MD, Lewis JW, Woods JH, Traynor JR. Characterization of the complex morphinan derivative BU72 as a high efficacy, long-lasting mu-opioid receptor agonist. Eur J Pharmacol. 2004 Sep 19; 499(1-2):107-16.
Score: 0.007
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Williams KL, Ko MC, Rice KC, Woods JH. Effect of opioid receptor antagonists on hypothalamic-pituitary-adrenal activity in rhesus monkeys. Psychoneuroendocrinology. 2003 May; 28(4):513-28.
Score: 0.006
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Butelman ER, Ko MC, Traynor JR, Vivian JA, Kreek MJ, Woods JH. GR89,696: a potent kappa-opioid agonist with subtype selectivity in rhesus monkeys. J Pharmacol Exp Ther. 2001 Sep; 298(3):1049-59.
Score: 0.006
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Kishioka S, Ko MC, Woods JH. Diltiazem enhances the analgesic but not the respiratory depressant effects of morphine in rhesus monkeys. Eur J Pharmacol. 2000 May 26; 397(1):85-92.
Score: 0.005
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Johnson MD, Ko M, Choo KS, Traynor JR, Mosberg HI, Naughton NN, Woods JH. The effects of the phyllolitorin analogue [desTrp(3), Leu(8)]phyllolitorin on scratching induced by bombesin and related peptides in rats. Brain Res. 1999 Aug 21; 839(1):194-8.
Score: 0.005
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Butelman ER, Ko MC, Sobczyk-Kojiro K, Mosberg HI, Van Bemmel B, Zernig G, Woods JH. kappa-Opioid receptor binding populations in rhesus monkey brain: relationship to an assay of thermal antinociception. J Pharmacol Exp Ther. 1998 May; 285(2):595-601.
Score: 0.004