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Connection

Mei-Chuan Ko to Carboxylic Ester Hydrolases

This is a "connection" page, showing publications Mei-Chuan Ko has written about Carboxylic Ester Hydrolases.
Connection Strength

2.225
  1. Collins GT, Brim RL, Noon KR, Narasimhan D, Lukacs NW, Sunahara RK, Woods JH, Ko MC. Repeated administration of a mutant cocaine esterase: effects on plasma cocaine levels, cocaine-induced cardiovascular activity, and immune responses in rhesus monkeys. J Pharmacol Exp Ther. 2012 Jul; 342(1):205-13.
    View in: PubMed
    Score: 0.428
  2. Collins GT, Carey KA, Narasimhan D, Nichols J, Berlin AA, Lukacs NW, Sunahara RK, Woods JH, Ko MC. Amelioration of the cardiovascular effects of cocaine in rhesus monkeys by a long-acting mutant form of cocaine esterase. Neuropsychopharmacology. 2011 Apr; 36(5):1047-59.
    View in: PubMed
    Score: 0.394
  3. Ko MC, Narasimhan D, Berlin AA, Lukacs NW, Sunahara RK, Woods JH. Effects of cocaine esterase following its repeated administration with cocaine in mice. Drug Alcohol Depend. 2009 May 01; 101(3):202-9.
    View in: PubMed
    Score: 0.344
  4. Ko MC, Bowen LD, Narasimhan D, Berlin AA, Lukacs NW, Sunahara RK, Cooper ZD, Woods JH. Cocaine esterase: interactions with cocaine and immune responses in mice. J Pharmacol Exp Ther. 2007 Feb; 320(2):926-33.
    View in: PubMed
    Score: 0.294
  5. Collins GT, Narasimhan D, Cunningham AR, Zaks ME, Nichols J, Ko MC, Sunahara RK, Woods JH. Long-lasting effects of a PEGylated mutant cocaine esterase (CocE) on the reinforcing and discriminative stimulus effects of cocaine in rats. Neuropsychopharmacology. 2012 Apr; 37(5):1092-103.
    View in: PubMed
    Score: 0.103
  6. Brim RL, Noon KR, Collins GT, Stein A, Nichols J, Narasimhan D, Ko MC, Woods JH, Sunahara RK. The fate of bacterial cocaine esterase (CocE): an in vivo study of CocE-mediated cocaine hydrolysis, CocE pharmacokinetics, and CocE elimination. J Pharmacol Exp Ther. 2012 Jan; 340(1):83-95.
    View in: PubMed
    Score: 0.103
  7. Narasimhan D, Collins GT, Nance MR, Nichols J, Edwald E, Chan J, Ko MC, Woods JH, Tesmer JJ, Sunahara RK. Subunit stabilization and polyethylene glycolation of cocaine esterase improves in vivo residence time. Mol Pharmacol. 2011 Dec; 80(6):1056-65.
    View in: PubMed
    Score: 0.102
  8. Collins GT, Zaks ME, Cunningham AR, St Clair C, Nichols J, Narasimhan D, Ko MC, Sunahara RK, Woods JH. Effects of a long-acting mutant bacterial cocaine esterase on acute cocaine toxicity in rats. Drug Alcohol Depend. 2011 Nov 01; 118(2-3):158-65.
    View in: PubMed
    Score: 0.100
  9. Narasimhan D, Nance MR, Gao D, Ko MC, Macdonald J, Tamburi P, Yoon D, Landry DM, Woods JH, Zhan CG, Tesmer JJ, Sunahara RK. Structural analysis of thermostabilizing mutations of cocaine esterase. Protein Eng Des Sel. 2010 Jul; 23(7):537-47.
    View in: PubMed
    Score: 0.093
  10. Park JB, Kwon YM, Lee TY, Brim R, Ko MC, Sunahara RK, Woods JH, Yang VC. PEGylation of bacterial cocaine esterase for protection against protease digestion and immunogenicity. J Control Release. 2010 Mar 03; 142(2):174-9.
    View in: PubMed
    Score: 0.090
  11. Collins GT, Brim RL, Narasimhan D, Ko MC, Sunahara RK, Zhan CG, Woods JH. Cocaine esterase prevents cocaine-induced toxicity and the ongoing intravenous self-administration of cocaine in rats. J Pharmacol Exp Ther. 2009 Nov; 331(2):445-55.
    View in: PubMed
    Score: 0.089
  12. Gao D, Narasimhan DL, Macdonald J, Brim R, Ko MC, Landry DW, Woods JH, Sunahara RK, Zhan CG. Thermostable variants of cocaine esterase for long-time protection against cocaine toxicity. Mol Pharmacol. 2009 Feb; 75(2):318-23.
    View in: PubMed
    Score: 0.084
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.