Roy Hantgan to Platelet Glycoprotein GPIIb-IIIa Complex
This is a "connection" page, showing publications Roy Hantgan has written about Platelet Glycoprotein GPIIb-IIIa Complex.
Connection Strength
3.143
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Hantgan RR, Stahle MC, Lord ST. Dynamic regulation of fibrinogen: integrin aIIbß3 binding. Biochemistry. 2010 Nov 02; 49(43):9217-25.
Score: 0.327
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Hantgan RR, Stahle MC. Integrin priming dynamics: mechanisms of integrin antagonist-promoted alphaIIbbeta3:PAC-1 molecular recognition. Biochemistry. 2009 Sep 08; 48(35):8355-65.
Score: 0.302
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Rocco M, Rosano C, Weisel JW, Horita DA, Hantgan RR. Integrin conformational regulation: uncoupling extension/tail separation from changes in the head region by a multiresolution approach. Structure. 2008 Jun; 16(6):954-64.
Score: 0.277
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Hantgan RR, Stahle MC, Horita DA. Entropy drives integrin alphaIIbbeta3:echistatin binding--evidence from surface plasmon resonance spectroscopy. Biochemistry. 2008 Mar 04; 47(9):2884-92.
Score: 0.271
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Hantgan RR, Stahle MC, Connor JH, Connor RF, Mousa SA. AlphaIIbbeta3 priming and clustering by orally active and intravenous integrin antagonists. J Thromb Haemost. 2007 Mar; 5(3):542-50.
Score: 0.250
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Hantgan RR, Stahle MC, Connor JH, Horita DA, Rocco M, McLane MA, Yakovlev S, Medved L. Integrin alphaIIbbeta3:ligand interactions are linked to binding-site remodeling. Protein Sci. 2006 Aug; 15(8):1893-906.
Score: 0.244
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Hantgan RR, Stahle MC, Connor JH, Lyles DS, Horita DA, Rocco M, Nagaswami C, Weisel JW, McLane MA. The disintegrin echistatin stabilizes integrin alphaIIbbeta3's open conformation and promotes its oligomerization. J Mol Biol. 2004 Oct 01; 342(5):1625-36.
Score: 0.215
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Hantgan RR, Gibbs W, Stahle MC, Aster RH, Peterson JA. Integrin clustering mechanisms explored with a soluble alphaIIbbeta3 ectodomain construct. Biochim Biophys Acta. 2004 Jul 01; 1700(1):19-25.
Score: 0.211
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Hantgan RR, Lyles DS, Mallett TC, Rocco M, Nagaswami C, Weisel JW. Ligand binding promotes the entropy-driven oligomerization of integrin alpha IIb beta 3. J Biol Chem. 2003 Jan 31; 278(5):3417-26.
Score: 0.188
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Hantgan RR, Stahle MC, Jerome WG, Nagaswami C, Weisel JW. Tirofiban blocks platelet adhesion to fibrin with minimal perturbation of GpIIb/IIIa structure. Thromb Haemost. 2002 May; 87(5):910-7.
Score: 0.182
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Hantgan RR, Rocco M, Nagaswami C, Weisel JW. Binding of a fibrinogen mimetic stabilizes integrin alphaIIbbeta3's open conformation. Protein Sci. 2001 Aug; 10(8):1614-26.
Score: 0.172
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Hantgan RR, Stahle M, Del Gaizo V, Adams M, Lasher T, Jerome WG, McKenzie M, Lyles DS. AlphaIIb's cytoplasmic domain is not required for ligand-induced clustering of integrin alphaIIbbeta3. Biochim Biophys Acta. 2001 Jul 25; 1540(1):82-95.
Score: 0.172
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Hantgan RR, Paumi C, Rocco M, Weisel JW. Effects of ligand-mimetic peptides Arg-Gly-Asp-X (X = Phe, Trp, Ser) on alphaIIbbeta3 integrin conformation and oligomerization. Biochemistry. 1999 Nov 02; 38(44):14461-74.
Score: 0.153
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Hantgan RR, Mousa SA. Inhibition of platelet-mediated clot retraction by integrin antagonists. Thromb Res. 1998 Mar 15; 89(6):271-9.
Score: 0.136
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Rocco M, Spotorno B, Hantgan RR. Modeling the alpha IIb beta 3 integrin solution conformation. Protein Sci. 1993 Dec; 2(12):2154-66.
Score: 0.025
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Huang TC, Jordan RE, Hantgan RR, Alevriadou BR. Differential effects of c7E3 Fab on thrombus formation and rt-PA-Mediated thrombolysis under flow conditions. Thromb Res. 2001 Jun 01; 102(5):411-25.
Score: 0.011
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Endenburg SC, Hantgan RR, Lindeboom-Blokzijl L, Lankhof H, Jerome WG, Lewis JC, Sixma JJ, de Groot PG. On the role of von Willebrand factor in promoting platelet adhesion to fibrin in flowing blood. Blood. 1995 Dec 01; 86(11):4158-65.
Score: 0.007