William Gmeiner to Fluorouracil
This is a "connection" page, showing publications William Gmeiner has written about Fluorouracil.
Connection Strength
1.961
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Gmeiner WH, Reinhold WC, Pommier Y. Genome-wide mRNA and microRNA profiling of the NCI 60 cell-line screen and comparison of FdUMP[10] with fluorouracil, floxuridine, and topoisomerase 1 poisons. Mol Cancer Ther. 2010 Dec; 9(12):3105-14.
Score: 0.378
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Gmeiner WH. Novel chemical strategies for thymidylate synthase inhibition. Curr Med Chem. 2005; 12(2):191-202.
Score: 0.251
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Gmeiner WH, Trump E, Wei C. Enhanced DNA-directed effects of FdUMP[10] compared to 5FU. Nucleosides Nucleotides Nucleic Acids. 2004; 23(1-2):401-10.
Score: 0.234
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Cui W, Gmeiner WH. Effect of 5-FU substitution and mutation on Sm protein binding to human U4 snRNA. Nucleosides Nucleotides Nucleic Acids. 2002; 21(2):139-54.
Score: 0.204
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Liu J, Kolath J, Anderson J, Kolar C, Lawson TA, Talmadge J, Gmeiner WH. Positive interaction between 5-FU and FdUMP[10] in the inhibition of human colorectal tumor cell proliferation. Antisense Nucleic Acid Drug Dev. 1999 Oct; 9(5):481-6.
Score: 0.174
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Liu J, Skradis A, Kolar C, Kolath J, Anderson J, Lawson T, Talmadge J, Gmeiner WH. Increased cytotoxicity and decreased in vivo toxicity of FdUMP[10] relative to 5-FU. Nucleosides Nucleotides. 1999 Aug; 18(8):1789-802.
Score: 0.172
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Sahasrabudhe PV, Gmeiner WH. Solution structures of 5-fluorouracil-substituted RNA duplexes containing G-U wobble base pairs. Biochemistry. 1997 May 20; 36(20):5981-91.
Score: 0.148
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Sahasrabudhe PV, Pon RT, Gmeiner WH. Solution structures of 5-fluorouracil-substituted DNA and RNA decamer duplexes. Biochemistry. 1996 Oct 22; 35(42):13597-608.
Score: 0.142
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Gmeiner WH, Lema-Tome C, Gibo D, Jennings-Gee J, Milligan C, Debinski W. Selective anti-tumor activity of the novel fluoropyrimidine polymer F10 towards G48a orthotopic GBM tumors. J Neurooncol. 2014 Feb; 116(3):447-54.
Score: 0.117
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Bijnsdorp IV, Comijn EM, Padron JM, Gmeiner WH, Peters GJ. Mechanisms of action of FdUMP[10]: metabolite activation and thymidylate synthase inhibition. Oncol Rep. 2007 Jul; 18(1):287-91.
Score: 0.075
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Liu J, Kolar C, Lawson TA, Gmeiner WH. Targeted drug delivery to chemoresistant cells: folic acid derivatization of FdUMP[10] enhances cytotoxicity toward 5-FU-resistant human colorectal tumor cells. J Org Chem. 2001 Aug 24; 66(17):5655-63.
Score: 0.050
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Liao ZY, Sordet O, Zhang HL, Kohlhagen G, Antony S, Gmeiner WH, Pommier Y. A novel polypyrimidine antitumor agent FdUMP[10] induces thymineless death with topoisomerase I-DNA complexes. Cancer Res. 2005 Jun 01; 65(11):4844-51.
Score: 0.016