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Mark Chappell to Animals

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This is a "connection" page, showing publications Mark Chappell has written about Animals.
Mark Chappell
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2.892
Animals
  1. South AM, Shaltout HA, Washburn LK, Hendricks AS, Diz DI, Chappell MC. Fetal programming and the angiotensin-(1-7) axis: a review of the experimental and clinical data. Clin Sci (Lond). 2019 01 15; 133(1):55-74.
    View in: PubMed
    Score: 0.073
  2. Yousif MHM, Benter IF, Diz DI, Chappell MC. Angiotensin-(1-7)-dependent vasorelaxation of the renal artery exhibits unique angiotensin and bradykinin receptor selectivity. Peptides. 2017 04; 90:10-16.
    View in: PubMed
    Score: 0.064
  3. Brosnihan KB, Chappell MC. Measurement of Angiotensin Peptides: HPLC-RIA. Methods Mol Biol. 2017; 1527:81-99.
    View in: PubMed
    Score: 0.063
  4. Wilson BA, Chappell MC. Assessment of the Renin-Angiotensin System in Cellular Organelle: New Arenas for Study in the Mitochondria. Methods Mol Biol. 2017; 1614:99-121.
    View in: PubMed
    Score: 0.063
  5. Wilson BA, Cruz-Diaz N, Su Y, Rose JC, Gwathmey TM, Chappell MC. Angiotensinogen import in isolated proximal tubules: evidence for mitochondrial trafficking and uptake. Am J Physiol Renal Physiol. 2017 05 01; 312(5):F879-F886.
    View in: PubMed
    Score: 0.063
  6. Ferrara AN, Luck JB, Chappell MC. Twostriped Walkingstick Targets Human Eye With Chemical Defense Spray. Wilderness Environ Med. 2016 Jun; 27(2):259-61.
    View in: PubMed
    Score: 0.060
  7. Chappell MC. Reply to "Letter to the editor: Angiotensin quantification by mass spectrometry". . 2016 Feb 01; 310(3):H454.
    View in: PubMed
    Score: 0.060
  8. Wilson BA, Nautiyal M, Gwathmey TM, Rose JC, Chappell MC. Evidence for a mitochondrial angiotensin-(1-7) system in the kidney. Am J Physiol Renal Physiol. 2016 04 01; 310(7):F637-F645.
    View in: PubMed
    Score: 0.059
  9. Chappell MC. Biochemical evaluation of the renin-angiotensin system: the good, bad, and absolute? . 2016 Jan 15; 310(2):H137-52.
    View in: PubMed
    Score: 0.058
  10. Wilson BA, Cruz-Diaz N, Marshall AC, Pirro NT, Su Y, Gwathmey TM, Rose JC, Chappell MC. An angiotensin-(1-7) peptidase in the kidney cortex, proximal tubules, and human HK-2 epithelial cells that is distinct from insulin-degrading enzyme. Am J Physiol Renal Physiol. 2015 Mar 15; 308(6):F594-601.
    View in: PubMed
    Score: 0.055
  11. Alzayadneh EM, Chappell MC. Angiotensin-(1-7) abolishes AGE-induced cellular hypertrophy and myofibroblast transformation via inhibition of ERK1/2. Cell Signal. 2014 Dec; 26(12):3027-35.
    View in: PubMed
    Score: 0.054
  12. Alzayadneh EM, Chappell MC. Nuclear expression of renin-angiotensin system components in NRK-52E renal epithelial cells. J Renin Angiotensin Aldosterone Syst. 2015 Dec; 16(4):1135-48.
    View in: PubMed
    Score: 0.053
  13. Wilson BA, Marshall AC, Alzayadneh EM, Chappell MC. The ins and outs of angiotensin processing within the kidney. . 2014 Sep 01; 307(5):R487-9.
    View in: PubMed
    Score: 0.053
  14. Marshall AC, Pirro NT, Rose JC, Diz DI, Chappell MC. Evidence for an angiotensin-(1-7) neuropeptidase expressed in the brain medulla and CSF of sheep. J Neurochem. 2014 Jul; 130(2):313-23.
    View in: PubMed
    Score: 0.053
  15. Marshall AC, Shaltout HA, Pirro NT, Rose JC, Diz DI, Chappell MC. Enhanced activity of an angiotensin-(1-7) neuropeptidase in glucocorticoid-induced fetal programming. Peptides. 2014 Feb; 52:74-81.
    View in: PubMed
    Score: 0.051
  16. Lindsey SH, Liu L, Chappell MC. Vasodilation by GPER in mesenteric arteries involves both endothelial nitric oxide and smooth muscle cAMP signaling. Steroids. 2014 Mar; 81:99-102.
    View in: PubMed
    Score: 0.051
  17. Marshall AC, Shaltout HA, Pirro NT, Rose JC, Diz DI, Chappell MC. Antenatal betamethasone exposure is associated with lower ANG-(1-7) and increased ACE in the CSF of adult sheep. . 2013 Oct 01; 305(7):R679-88.
    View in: PubMed
    Score: 0.050
  18. Chappell MC. Of diabetic mice and ACE2: a new biomarker of renal disease? Am J Physiol Renal Physiol. 2013 Oct 01; 305(7):F970-2.
    View in: PubMed
    Score: 0.050
  19. Lindsey SH, da Silva AS, Silva MS, Chappell MC. Reduced vasorelaxation to estradiol and G-1 in aged female and adult male rats is associated with GPR30 downregulation. Am J Physiol Endocrinol Metab. 2013 Jul 01; 305(1):E113-8.
    View in: PubMed
    Score: 0.049
  20. Yamaleyeva LM, Lindsey SH, Varagic J, Zhang LL, Gallagher PE, Chen AF, Chappell MC. Amelioration of renal injury and oxidative stress by the nNOS inhibitor L-VNIO in the salt-sensitive mRen2.Lewis congenic rat. J Cardiovasc Pharmacol. 2012 Jun; 59(6):529-38.
    View in: PubMed
    Score: 0.046
  21. Harrison-Bernard LM, Chappell MC. Unraveling the glomerular RAS: one peptidase at a time. Am J Physiol Renal Physiol. 2012 Aug 01; 303(3):F373-4.
    View in: PubMed
    Score: 0.046
  22. Westwood BM, Chappell MC. Divergent pathways for the angiotensin-(1-12) metabolism in the rat circulation and kidney. Peptides. 2012 Jun; 35(2):190-5.
    View in: PubMed
    Score: 0.046
  23. Yamaleyeva LM, Gilliam-Davis S, Almeida I, Brosnihan KB, Lindsey SH, Chappell MC. Differential regulation of circulating and renal ACE2 and ACE in hypertensive mRen2.Lewis rats with early-onset diabetes. Am J Physiol Renal Physiol. 2012 Jun 01; 302(11):F1374-84.
    View in: PubMed
    Score: 0.045
  24. Gwathmey TM, Alzayadneh EM, Pendergrass KD, Chappell MC. Novel roles of nuclear angiotensin receptors and signaling mechanisms. . 2012 Mar 01; 302(5):R518-30.
    View in: PubMed
    Score: 0.045
  25. Lindsey SH, Chappell MC. Evidence that the G protein-coupled membrane receptor GPR30 contributes to the cardiovascular actions of estrogen. Gend Med. 2011 Dec; 8(6):343-54.
    View in: PubMed
    Score: 0.045
  26. Lindsey SH, Yamaleyeva LM, Brosnihan KB, Gallagher PE, Chappell MC. Estrogen receptor GPR30 reduces oxidative stress and proteinuria in the salt-sensitive female mRen2.Lewis rat. Hypertension. 2011 Oct; 58(4):665-71.
    View in: PubMed
    Score: 0.044
  27. Lindsey SH, Carver KA, Prossnitz ER, Chappell MC. Vasodilation in response to the GPR30 agonist G-1 is not different from estradiol in the mRen2.Lewis female rat. J Cardiovasc Pharmacol. 2011 May; 57(5):598-603.
    View in: PubMed
    Score: 0.043
  28. Gwathmey TM, Shaltout HA, Rose JC, Diz DI, Chappell MC. Glucocorticoid-induced fetal programming alters the functional complement of angiotensin receptor subtypes within the kidney. Hypertension. 2011 Mar; 57(3):620-6.
    View in: PubMed
    Score: 0.042
  29. Gwathmey TM, Westwood BM, Pirro NT, Tang L, Rose JC, Diz DI, Chappell MC. Nuclear angiotensin-(1-7) receptor is functionally coupled to the formation of nitric oxide. Am J Physiol Renal Physiol. 2010 Nov; 299(5):F983-90.
    View in: PubMed
    Score: 0.041
  30. Cohen JA, Lindsey SH, Pirro NT, Brosnihan KB, Gallagher PE, Chappell MC. Influence of estrogen depletion and salt loading on renal angiotensinogen expression in the mRen(2).Lewis strain. Am J Physiol Renal Physiol. 2010 Jul; 299(1):F35-42.
    View in: PubMed
    Score: 0.040
  31. Chappell MC. Does ACE2 contribute to the development of hypertension? Hypertens Res. 2010 Feb; 33(2):107-9.
    View in: PubMed
    Score: 0.039
  32. Gwathmey TM, Pendergrass KD, Reid SD, Rose JC, Diz DI, Chappell MC. Angiotensin-(1-7)-angiotensin-converting enzyme 2 attenuates reactive oxygen species formation to angiotensin II within the cell nucleus. Hypertension. 2010 Jan; 55(1):166-71.
    View in: PubMed
    Score: 0.039
  33. Pendergrass KD, Gwathmey TM, Michalek RD, Grayson JM, Chappell MC. The angiotensin II-AT1 receptor stimulates reactive oxygen species within the cell nucleus. Biochem Biophys Res Commun. 2009 Jun 26; 384(2):149-54.
    View in: PubMed
    Score: 0.037
  34. Lindsey SH, Cohen JA, Brosnihan KB, Gallagher PE, Chappell MC. Chronic treatment with the G protein-coupled receptor 30 agonist G-1 decreases blood pressure in ovariectomized mRen2.Lewis rats. Endocrinology. 2009 Aug; 150(8):3753-8.
    View in: PubMed
    Score: 0.037
  35. Gwathmey TM, Shaltout HA, Pendergrass KD, Pirro NT, Figueroa JP, Rose JC, Diz DI, Chappell MC. Nuclear angiotensin II type 2 (AT2) receptors are functionally linked to nitric oxide production. Am J Physiol Renal Physiol. 2009 Jun; 296(6):F1484-93.
    View in: PubMed
    Score: 0.037
  36. Shaltout HA, Figueroa JP, Rose JC, Diz DI, Chappell MC. Alterations in circulatory and renal angiotensin-converting enzyme and angiotensin-converting enzyme 2 in fetal programmed hypertension. Hypertension. 2009 Feb; 53(2):404-8.
    View in: PubMed
    Score: 0.036
  37. Garabelli PJ, Modrall JG, Penninger JM, Ferrario CM, Chappell MC. Distinct roles for angiotensin-converting enzyme 2 and carboxypeptidase A in the processing of angiotensins within the murine heart. Exp Physiol. 2008 May; 93(5):613-21.
    View in: PubMed
    Score: 0.035
  38. Groban L, Yamaleyeva LM, Westwood BM, Houle TT, Lin M, Kitzman DW, Chappell MC. Progressive diastolic dysfunction in the female mRen(2). Lewis rat: influence of salt and ovarian hormones. J Gerontol A Biol Sci Med Sci. 2008 Jan; 63(1):3-11.
    View in: PubMed
    Score: 0.034
  39. Chappell MC, Westwood BM, Yamaleyeva LM. Differential effects of sex steroids in young and aged female mRen2.Lewis rats: a model of estrogen and salt-sensitive hypertension. Gend Med. 2008; 5 Suppl A:S65-75.
    View in: PubMed
    Score: 0.034
  40. Yamaleyeva LM, Pendergrass KD, Pirro NT, Gallagher PE, Groban L, Chappell MC. Ovariectomy is protective against renal injury in the high-salt-fed older mRen2. Lewis rat. . 2007 Oct; 293(4):H2064-71.
    View in: PubMed
    Score: 0.033
  41. Yamaleyeva LM, Gallagher PE, Vinsant S, Chappell MC. Discoordinate regulation of renal nitric oxide synthase isoforms in ovariectomized mRen2. Lewis rats. . 2007 Feb; 292(2):R819-26.
    View in: PubMed
    Score: 0.031
  42. Shaltout HA, Westwood BM, Averill DB, Ferrario CM, Figueroa JP, Diz DI, Rose JC, Chappell MC. Angiotensin metabolism in renal proximal tubules, urine, and serum of sheep: evidence for ACE2-dependent processing of angiotensin II. Am J Physiol Renal Physiol. 2007 Jan; 292(1):F82-91.
    View in: PubMed
    Score: 0.031
  43. Chappell MC, Yamaleyeva LM, Westwood BM. Estrogen and salt sensitivity in the female mRen(2). Lewis rat. . 2006 Nov; 291(5):R1557-63.
    View in: PubMed
    Score: 0.031
  44. Pendergrass KD, Averill DB, Ferrario CM, Diz DI, Chappell MC. Differential expression of nuclear AT1 receptors and angiotensin II within the kidney of the male congenic mRen2. Lewis rat. Am J Physiol Renal Physiol. 2006 Jun; 290(6):F1497-506.
    View in: PubMed
    Score: 0.030
  45. Ferrario CM, Jessup J, Gallagher PE, Averill DB, Brosnihan KB, Ann Tallant E, Smith RD, Chappell MC. Effects of renin-angiotensin system blockade on renal angiotensin-(1-7) forming enzymes and receptors. Kidney Int. 2005 Nov; 68(5):2189-96.
    View in: PubMed
    Score: 0.029
  46. Brosnihan KB, Neves LA, Chappell MC. Does the angiotensin-converting enzyme (ACE)/ACE2 balance contribute to the fate of angiotensin peptides in programmed hypertension? Hypertension. 2005 Nov; 46(5):1097-9.
    View in: PubMed
    Score: 0.029
  47. Modrall JG, Sadjadi J, Brosnihan KB, Gallagher PE, Yu CH, Kramer GL, Bernstein KE, Chappell MC. Depletion of tissue angiotensin-converting enzyme differentially influences the intrarenal and urinary expression of angiotensin peptides. Hypertension. 2004 Apr; 43(4):849-53.
    View in: PubMed
    Score: 0.026
  48. Chappell MC, Modrall JG, Diz DI, Ferrario CM. Novel aspects of the renal renin-angiotensin system: angiotensin-(1-7), ACE2 and blood pressure regulation. Contrib Nephrol. 2004; 143:77-89.
    View in: PubMed
    Score: 0.026
  49. Chappell MC, Gallagher PE, Averill DB, Ferrario CM, Brosnihan KB. Estrogen or the AT1 antagonist olmesartan reverses the development of profound hypertension in the congenic mRen2. Lewis rat. Hypertension. 2003 Oct; 42(4):781-6.
    View in: PubMed
    Score: 0.025
  50. Leung PS, Chappell MC. A local pancreatic renin-angiotensin system: endocrine and exocrine roles. Int J Biochem Cell Biol. 2003 Jun; 35(6):838-46.
    View in: PubMed
    Score: 0.025
  51. Hendricks AS, Lawson MJ, Figueroa JP, Chappell MC, Diz DI, Shaltout HA. Central ANG-(1-7) infusion improves blood pressure regulation in antenatal betamethasone-exposed sheep and reveals sex-dependent effects on oxidative stress. . 2019 06 01; 316(6):H1458-H1467.
    View in: PubMed
    Score: 0.019
  52. Nautiyal M, Shaltout HA, Chappell MC, Diz DI. Comparison of Candesartan and Angiotensin-(1-7) Combination to Mito-TEMPO Treatment for Normalizing Blood Pressure and Sympathovagal Balance in (mREN2)27 Rats. J Cardiovasc Pharmacol. 2019 03; 73(3):143-148.
    View in: PubMed
    Score: 0.018
  53. Hendricks AS, Shaltout HA, Westwood BM, Chappell MC, Diz DI. Sex-dependent expression of brain medullary MAP and PI3 kinases in adult sheep with antenatal betamethasone exposure. Clin Sci (Lond). 2018 09 14; 132(17):1953-1962.
    View in: PubMed
    Score: 0.018
  54. Sodhi CP, Wohlford-Lenane C, Yamaguchi Y, Prindle T, Fulton WB, Wang S, McCray PB, Chappell M, Hackam DJ, Jia H. Attenuation of pulmonary ACE2 activity impairs inactivation of des-Arg9 bradykinin/BKB1R axis and facilitates LPS-induced neutrophil infiltration. . 2018 01 01; 314(1):L17-L31.
    View in: PubMed
    Score: 0.017
  55. Su Y, Bi J, Pulgar VM, Chappell MC, Rose JC. Antenatal betamethasone attenuates the angiotensin-(1-7)-Mas receptor-nitric oxide axis in isolated proximal tubule cells. Am J Physiol Renal Physiol. 2017 06 01; 312(6):F1056-F1062.
    View in: PubMed
    Score: 0.016
  56. Koch A, Gulani J, King G, Hieber K, Chappell M, Ossetrova N. Establishment of Early Endpoints in Mouse Total-Body Irradiation Model. PLoS One. 2016; 11(8):e0161079.
    View in: PubMed
    Score: 0.016
  57. Moroni M, Port M, Gulani J, Chappell M, Abend M. Significance of Bioindicators for Early Predictions on Diagnosis and Therapy of Irradiated Minipigs. Health Phys. 2016 08; 111(2):160-8.
    View in: PubMed
    Score: 0.015
  58. Liu L, Kashyap S, Murphy B, Hutson DD, Budish RA, Trimmer EH, Zimmerman MA, Trask AJ, Miller KS, Chappell MC, Lindsey SH. GPER activation ameliorates aortic remodeling induced by salt-sensitive hypertension. . 2016 Apr 15; 310(8):H953-61.
    View in: PubMed
    Score: 0.015
  59. Chen K, Bi J, Su Y, Chappell MC, Rose JC. Sex-Specific Changes in Renal Angiotensin-Converting Enzyme and Angiotensin-Converting Enzyme 2 Gene Expression and Enzyme Activity at Birth and Over the First Year of Life. Reprod Sci. 2016 Feb; 23(2):200-10.
    View in: PubMed
    Score: 0.014
  60. Su Y, Bi J, Pulgar VM, Figueroa J, Chappell M, Rose JC. Antenatal glucocorticoid treatment alters Na+ uptake in renal proximal tubule cells from adult offspring in a sex-specific manner. Am J Physiol Renal Physiol. 2015 Jun 01; 308(11):F1268-75.
    View in: PubMed
    Score: 0.014
  61. Bi J, Contag SA, Chen K, Su Y, Figueroa JP, Chappell MC, Rose JC. Sex-specific effect of antenatal betamethasone exposure on renal oxidative stress induced by angiotensins in adult sheep. Am J Physiol Renal Physiol. 2014 Nov 01; 307(9):F1013-22.
    View in: PubMed
    Score: 0.014
  62. Zhao Z, Wang H, Jessup JA, Lindsey SH, Chappell MC, Groban L. Role of estrogen in diastolic dysfunction. . 2014 Mar 01; 306(5):H628-40.
    View in: PubMed
    Score: 0.013
  63. Wang H, Jessup JA, Zhao Z, Da Silva J, Lin M, MacNamara LM, Ahmad S, Chappell MC, Ferrario CM, Groban L. Characterization of the cardiac renin angiotensin system in oophorectomized and estrogen-replete mRen2.Lewis rats. PLoS One. 2013; 8(10):e76992.
    View in: PubMed
    Score: 0.013
  64. Marshall AC, Shaltout HA, Nautiyal M, Rose JC, Chappell MC, Diz DI. Fetal betamethasone exposure attenuates angiotensin-(1-7)-Mas receptor expression in the dorsal medulla of adult sheep. Peptides. 2013 Jun; 44:25-31.
    View in: PubMed
    Score: 0.012
  65. Nautiyal M, Shaltout HA, de Lima DC, do Nascimento K, Chappell MC, Diz DI. Response to Angiotensin-(1-7) and Bradykinin in Baroreceptor Reflex Sensitivity in Hypertension. Hypertension. 2013 Feb; 61(2):e20.
    View in: PubMed
    Score: 0.012
  66. Bi J, Contag SA, Carey LC, Tang L, Valego NK, Chappell MC, Rose JC. Antenatal betamethasone exposure alters renal responses to angiotensin-(1-7) in uninephrectomized adult male sheep. J Renin Angiotensin Aldosterone Syst. 2013 Dec; 14(4):290-8.
    View in: PubMed
    Score: 0.012
  67. Nautiyal M, Shaltout HA, de Lima DC, do Nascimento K, Chappell MC, Diz DI. Central angiotensin-(1-7) improves vagal function independent of blood pressure in hypertensive (mRen2)27 rats. Hypertension. 2012 Nov; 60(5):1257-65.
    View in: PubMed
    Score: 0.012
  68. Nautiyal M, Katakam PV, Busija DW, Gallagher PE, Tallant EA, Chappell MC, Diz DI. Differences in oxidative stress status and expression of MKP-1 in dorsal medulla of transgenic rats with altered brain renin-angiotensin system. . 2012 Oct 15; 303(8):R799-806.
    View in: PubMed
    Score: 0.012
  69. Garcia-Espinosa MA, Shaltout HA, Gallagher PE, Chappell MC, Diz DI. In vivo expression of angiotensin-(1-7) lowers blood pressure and improves baroreflex function in transgenic (mRen2)27 rats. J Cardiovasc Pharmacol. 2012 Aug; 60(2):150-7.
    View in: PubMed
    Score: 0.012
  70. Shaltout HA, Rose JC, Chappell MC, Diz DI. Angiotensin-(1-7) deficiency and baroreflex impairment precede the antenatal Betamethasone exposure-induced elevation in blood pressure. Hypertension. 2012 Feb; 59(2):453-8.
    View in: PubMed
    Score: 0.011
  71. Ahmad S, Simmons T, Varagic J, Moniwa N, Chappell MC, Ferrario CM. Chymase-dependent generation of angiotensin II from angiotensin-(1-12) in human atrial tissue. PLoS One. 2011; 6(12):e28501.
    View in: PubMed
    Score: 0.011
  72. Bharadwaj MS, Strawn WB, Groban L, Yamaleyeva LM, Chappell MC, Horta C, Atkins K, Firmes L, Gurley SB, Brosnihan KB. Angiotensin-converting enzyme 2 deficiency is associated with impaired gestational weight gain and fetal growth restriction. Hypertension. 2011 Nov; 58(5):852-8.
    View in: PubMed
    Score: 0.011
  73. Isa K, Arnold AC, Westwood BM, Chappell MC, Diz DI. Angiotensin-converting enzyme inhibition, but not AT(1) receptor blockade, in the solitary tract nucleus improves baroreflex sensitivity in anesthetized transgenic hypertensive (mRen2)27 rats. Hypertens Res. 2011 Dec; 34(12):1257-62.
    View in: PubMed
    Score: 0.011
  74. Jessup JA, Zhang L, Chen AF, Presley TD, Kim-Shapiro DB, Chappell MC, Wang H, Groban L. Neuronal nitric oxide synthase inhibition improves diastolic function and reduces oxidative stress in ovariectomized mRen2.Lewis rats. Menopause. 2011 Jun; 18(6):698-708.
    View in: PubMed
    Score: 0.011
  75. Gilliam-Davis S, Gallagher PE, Payne VS, Kasper SO, Tommasi EN, Westwood BM, Robbins ME, Chappell MC, Diz DI. Long-term systemic angiotensin II type 1 receptor blockade regulates mRNA expression of dorsomedial medulla renin-angiotensin system components. Physiol Genomics. 2011 Jul 14; 43(13):829-35.
    View in: PubMed
    Score: 0.011
  76. Benter IF, Yousif MH, Al-Saleh FM, Raghupathy R, Chappell MC, Diz DI. Angiotensin-(1-7) blockade attenuates captopril- or hydralazine-induced cardiovascular protection in spontaneously hypertensive rats treated with NG-nitro-L-arginine methyl ester. J Cardiovasc Pharmacol. 2011 May; 57(5):559-67.
    View in: PubMed
    Score: 0.011
  77. Shaltout HA, Chappell MC, Rose JC, Diz DI. Exaggerated sympathetic mediated responses to behavioral or pharmacological challenges following antenatal betamethasone exposure. Am J Physiol Endocrinol Metab. 2011 Jun; 300(6):E979-85.
    View in: PubMed
    Score: 0.011
  78. Ahmad S, Varagic J, Westwood BM, Chappell MC, Ferrario CM. Uptake and metabolism of the novel peptide angiotensin-(1-12) by neonatal cardiac myocytes. PLoS One. 2011 Jan 10; 6(1):e15759.
    View in: PubMed
    Score: 0.010
  79. Jessup JA, Lindsey SH, Wang H, Chappell MC, Groban L. Attenuation of salt-induced cardiac remodeling and diastolic dysfunction by the GPER agonist G-1 in female mRen2.Lewis rats. PLoS One. 2010 Nov 03; 5(11):e15433.
    View in: PubMed
    Score: 0.010
  80. Embers ME, Doyle LA, Whitehouse CA, Selby EB, Chappell M, Philipp MT. Characterization of a Moraxella species that causes epistaxis in macaques. Vet Microbiol. 2011 Jan 27; 147(3-4):367-75.
    View in: PubMed
    Score: 0.010
  81. Arnold AC, Isa K, Shaltout HA, Nautiyal M, Ferrario CM, Chappell MC, Diz DI. Angiotensin-(1-12) requires angiotensin converting enzyme and AT1 receptors for cardiovascular actions within the solitary tract nucleus. . 2010 Sep; 299(3):H763-71.
    View in: PubMed
    Score: 0.010
  82. Tang L, Bi J, Valego N, Carey L, Figueroa J, Chappell M, Rose JC. Prenatal betamethasone exposure alters renal function in immature sheep: sex differences in effects. . 2010 Sep; 299(3):R793-803.
    View in: PubMed
    Score: 0.010
  83. Shaltout HA, Rose JC, Figueroa JP, Chappell MC, Diz DI, Averill DB. Acute AT(1)-receptor blockade reverses the hemodynamic and baroreflex impairment in adult sheep exposed to antenatal betamethasone. . 2010 Aug; 299(2):H541-7.
    View in: PubMed
    Score: 0.010
  84. Dhaunsi GS, Yousif MH, Akhtar S, Chappell MC, Diz DI, Benter IF. Angiotensin-(1-7) prevents diabetes-induced attenuation in PPAR-gamma and catalase activities. Eur J Pharmacol. 2010 Jul 25; 638(1-3):108-14.
    View in: PubMed
    Score: 0.010
  85. Trask AJ, Groban L, Westwood BM, Varagic J, Ganten D, Gallagher PE, Chappell MC, Ferrario CM. Inhibition of angiotensin-converting enzyme 2 exacerbates cardiac hypertrophy and fibrosis in Ren-2 hypertensive rats. Am J Hypertens. 2010 Jun; 23(6):687-93.
    View in: PubMed
    Score: 0.010
  86. Contag SA, Bi J, Chappell MC, Rose JC. Developmental effect of antenatal exposure to betamethasone on renal angiotensin II activity in the young adult sheep. Am J Physiol Renal Physiol. 2010 Apr; 298(4):F847-56.
    View in: PubMed
    Score: 0.010
  87. Brosnihan KB, Hering L, Dechend R, Chappell MC, Herse F. Increased angiotensin II in the mesometrial triangle of a transgenic rat model of preeclampsia. Hypertension. 2010 Feb; 55(2):562-6.
    View in: PubMed
    Score: 0.010
  88. Varagic J, Ahmad S, Brosnihan KB, Groban L, Chappell MC, Tallant EA, Gallagher PE, Ferrario CM. Decreased cardiac Ang-(1-7) is associated with salt-induced cardiac remodeling and dysfunction. Ther Adv Cardiovasc Dis. 2010 Feb; 4(1):17-25.
    View in: PubMed
    Score: 0.010
  89. Silberman Y, Bajo M, Chappell AM, Christian DT, Cruz M, Diaz MR, Kash T, Lack AK, Messing RO, Siggins GR, Winder D, Roberto M, McCool BA, Weiner JL. Neurobiological mechanisms contributing to alcohol-stress-anxiety interactions. Alcohol. 2009 Nov; 43(7):509-19.
    View in: PubMed
    Score: 0.010
  90. Park S, Bivona BJ, Kobori H, Seth DM, Chappell MC, Lazartigues E, Harrison-Bernard LM. Major role for ACE-independent intrarenal ANG II formation in type II diabetes. Am J Physiol Renal Physiol. 2010 Jan; 298(1):F37-48.
    View in: PubMed
    Score: 0.010
  91. Jessup JA, Westwood BM, Chappell MC, Groban L. Dual ACE-inhibition and AT1 receptor antagonism improves ventricular lusitropy without affecting cardiac fibrosis in the congenic mRen2.Lewis rat. Ther Adv Cardiovasc Dis. 2009 Aug; 3(4):245-57.
    View in: PubMed
    Score: 0.009
  92. Isa K, García-Espinosa MA, Arnold AC, Pirro NT, Tommasi EN, Ganten D, Chappell MC, Ferrario CM, Diz DI. Chronic immunoneutralization of brain angiotensin-(1-12) lowers blood pressure in transgenic (mRen2)27 hypertensive rats. . 2009 Jul; 297(1):R111-5.
    View in: PubMed
    Score: 0.009
  93. Ferrario CM, Varagic J, Habibi J, Nagata S, Kato J, Chappell MC, Trask AJ, Kitamura K, Whaley-Connell A, Sowers JR. Differential regulation of angiotensin-(1-12) in plasma and cardiac tissue in response to bilateral nephrectomy. . 2009 Apr; 296(4):H1184-92.
    View in: PubMed
    Score: 0.009
  94. Tang L, Carey LC, Bi J, Valego N, Sun X, Deibel P, Perrott J, Figueroa JP, Chappell MC, Rose JC. Gender differences in the effects of antenatal betamethasone exposure on renal function in adult sheep. . 2009 Feb; 296(2):R309-17.
    View in: PubMed
    Score: 0.009
  95. Kantorowicz L, Valego NK, Tang L, Figueroa JP, Chappell MC, Carey LC, Rose JC. Plasma and renal renin concentrations in adult sheep after prenatal betamethasone exposure. Reprod Sci. 2008 Oct; 15(8):831-8.
    View in: PubMed
    Score: 0.009
  96. Varagic J, Trask AJ, Jessup JA, Chappell MC, Ferrario CM. New angiotensins. J Mol Med (Berl). 2008 Jun; 86(6):663-71.
    View in: PubMed
    Score: 0.009
  97. Jessup JA, Trask AJ, Chappell MC, Nagata S, Kato J, Kitamura K, Ferrario CM. Localization of the novel angiotensin peptide, angiotensin-(1-12), in heart and kidney of hypertensive and normotensive rats. . 2008 Jun; 294(6):H2614-8.
    View in: PubMed
    Score: 0.009
  98. Trask AJ, Jessup JA, Chappell MC, Ferrario CM. Angiotensin-(1-12) is an alternate substrate for angiotensin peptide production in the heart. . 2008 May; 294(5):H2242-7.
    View in: PubMed
    Score: 0.009
  99. Diz DI, Garcia-Espinosa MA, Gegick S, Tommasi EN, Ferrario CM, Ann Tallant E, Chappell MC, Gallagher PE. Injections of angiotensin-converting enzyme 2 inhibitor MLN4760 into nucleus tractus solitarii reduce baroreceptor reflex sensitivity for heart rate control in rats. Exp Physiol. 2008 May; 93(5):694-700.
    View in: PubMed
    Score: 0.009
  100. Benter IF, Yousif MH, Dhaunsi GS, Kaur J, Chappell MC, Diz DI. Angiotensin-(1-7) prevents activation of NADPH oxidase and renal vascular dysfunction in diabetic hypertensive rats. Am J Nephrol. 2008; 28(1):25-33.
    View in: PubMed
    Score: 0.008
  101. Oudit GY, Kassiri Z, Patel MP, Chappell M, Butany J, Backx PH, Tsushima RG, Scholey JW, Khokha R, Penninger JM. Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice. Cardiovasc Res. 2007 Jul 01; 75(1):29-39.
    View in: PubMed
    Score: 0.008
  102. Trask AJ, Averill DB, Ganten D, Chappell MC, Ferrario CM. Primary role of angiotensin-converting enzyme-2 in cardiac production of angiotensin-(1-7) in transgenic Ren-2 hypertensive rats. . 2007 Jun; 292(6):H3019-24.
    View in: PubMed
    Score: 0.008
  103. Jessup JA, Gallagher PE, Averill DB, Brosnihan KB, Tallant EA, Chappell MC, Ferrario CM. Effect of angiotensin II blockade on a new congenic model of hypertension derived from transgenic Ren-2 rats. . 2006 Nov; 291(5):H2166-72.
    View in: PubMed
    Score: 0.008
  104. Groban L, Pailes NA, Bennett CD, Carter CS, Chappell MC, Kitzman DW, Sonntag WE. Growth hormone replacement attenuates diastolic dysfunction and cardiac angiotensin II expression in senescent rats. J Gerontol A Biol Sci Med Sci. 2006 Jan; 61(1):28-35.
    View in: PubMed
    Score: 0.007
  105. Chen Y, Chen H, Hoffmann A, Cool DR, Diz DI, Chappell MC, Chen AF, Chen A, Morris M. Adenovirus-mediated small-interference RNA for in vivo silencing of angiotensin AT1a receptors in mouse brain. Hypertension. 2006 Feb; 47(2):230-7.
    View in: PubMed
    Score: 0.007
  106. Gallagher PE, Chappell MC, Ferrario CM, Tallant EA. Distinct roles for ANG II and ANG-(1-7) in the regulation of angiotensin-converting enzyme 2 in rat astrocytes. . 2006 Feb; 290(2):C420-6.
    View in: PubMed
    Score: 0.007
  107. Sadjadi J, Kramer GL, Yu CH, Burress Welborn M, Chappell MC, Gregory Modrall J. Angiotensin converting enzyme-independent angiotensin ii production by chymase is up-regulated in the ischemic kidney in renovascular hypertension. J Surg Res. 2005 Aug; 127(2):65-9.
    View in: PubMed
    Score: 0.007
  108. Kuba K, Imai Y, Rao S, Gao H, Guo F, Guan B, Huan Y, Yang P, Zhang Y, Deng W, Bao L, Zhang B, Liu G, Wang Z, Chappell M, Liu Y, Zheng D, Leibbrandt A, Wada T, Slutsky AS, Liu D, Qin C, Jiang C, Penninger JM. A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury. Nat Med. 2005 Aug; 11(8):875-9.
    View in: PubMed
    Score: 0.007
  109. Ferrario CM, Jessup J, Chappell MC, Averill DB, Brosnihan KB, Tallant EA, Diz DI, Gallagher PE. Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2. Circulation. 2005 May 24; 111(20):2605-10.
    View in: PubMed
    Score: 0.007
  110. Averill DB, Ishiyama Y, Chappell MC, Ferrario CM. Cardiac angiotensin-(1-7) in ischemic cardiomyopathy. Circulation. 2003 Oct 28; 108(17):2141-6.
    View in: PubMed
    Score: 0.006
  111. Brosnihan KB, Neves LA, Joyner J, Averill DB, Chappell MC, Sarao R, Penninger J, Ferrario CM. Enhanced renal immunocytochemical expression of ANG-(1-7) and ACE2 during pregnancy. Hypertension. 2003 Oct; 42(4):749-53.
    View in: PubMed
    Score: 0.006
  112. Neves LA, Averill DB, Ferrario CM, Chappell MC, Aschner JL, Walkup MP, Brosnihan KB. Characterization of angiotensin-(1-7) receptor subtype in mesenteric arteries. Peptides. 2003 Mar; 24(3):455-62.
    View in: PubMed
    Score: 0.006
  113. Nakamura S, Averill DB, Chappell MC, Diz DI, Brosnihan KB, Ferrario CM. Angiotensin receptors contribute to blood pressure homeostasis in salt-depleted SHR. . 2003 Jan; 284(1):R164-73.
    View in: PubMed
    Score: 0.006
  114. Ferrario CM, Averill DB, Brosnihan KB, Chappell MC, Iskandar SS, Dean RH, Diz DI. Vasopeptidase inhibition and Ang-(1-7) in the spontaneously hypertensive rat. Kidney Int. 2002 Oct; 62(4):1349-57.
    View in: PubMed
    Score: 0.006
  115. Crackower MA, Sarao R, Oudit GY, Yagil C, Kozieradzki I, Scanga SE, Oliveira-dos-Santos AJ, da Costa J, Zhang L, Pei Y, Scholey J, Ferrario CM, Manoukian AS, Chappell MC, Backx PH, Yagil Y, Penninger JM. Angiotensin-converting enzyme 2 is an essential regulator of heart function. Nature. 2002 Jun 20; 417(6891):822-8.
    View in: PubMed
    Score: 0.006
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.