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Mark Chappell to Peptidyl-Dipeptidase A

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This is a "connection" page, showing publications Mark Chappell has written about Peptidyl-Dipeptidase A.
Mark Chappell
Connection Strength
8.208
Peptidyl-Dipeptidase A
  1. Chappell MC. Commentary for "Endocrine significance of SARS-CoV-2's Reliance on ACE2". Endocrinology. 2021 04 01; 162(4).
    View in: PubMed
    Score: 0.706
  2. South AM, Diz DI, Chappell MC. COVID-19, ACE2, and the cardiovascular consequences. Am J Physiol Heart Circ Physiol. 2020 05 01; 318(5):H1084-H1090.
    View in: PubMed
    Score: 0.659
  3. Marshall AC, Pirro NT, Rose JC, Diz DI, Chappell MC. Evidence for an angiotensin-(1-7) neuropeptidase expressed in the brain medulla and CSF of sheep. J Neurochem. 2014 Jul; 130(2):313-23.
    View in: PubMed
    Score: 0.436
  4. Marshall AC, Shaltout HA, Pirro NT, Rose JC, Diz DI, Chappell MC. Enhanced activity of an angiotensin-(1-7) neuropeptidase in glucocorticoid-induced fetal programming. Peptides. 2014 Feb; 52:74-81.
    View in: PubMed
    Score: 0.426
  5. Marshall AC, Shaltout HA, Pirro NT, Rose JC, Diz DI, Chappell MC. Antenatal betamethasone exposure is associated with lower ANG-(1-7) and increased ACE in the CSF of adult sheep. . 2013 Oct 01; 305(7):R679-88.
    View in: PubMed
    Score: 0.416
  6. Chappell MC. Of diabetic mice and ACE2: a new biomarker of renal disease? Am J Physiol Renal Physiol. 2013 Oct 01; 305(7):F970-2.
    View in: PubMed
    Score: 0.414
  7. Westwood BM, Chappell MC. Divergent pathways for the angiotensin-(1-12) metabolism in the rat circulation and kidney. Peptides. 2012 Jun; 35(2):190-5.
    View in: PubMed
    Score: 0.378
  8. Yamaleyeva LM, Gilliam-Davis S, Almeida I, Brosnihan KB, Lindsey SH, Chappell MC. Differential regulation of circulating and renal ACE2 and ACE in hypertensive mRen2.Lewis rats with early-onset diabetes. Am J Physiol Renal Physiol. 2012 Jun 01; 302(11):F1374-84.
    View in: PubMed
    Score: 0.376
  9. Chappell MC. Angiotensin-converting enzyme 2 autoantibodies: further evidence for a role of the renin-angiotensin system in inflammation. Arthritis Res Ther. 2010; 12(3):128.
    View in: PubMed
    Score: 0.335
  10. Chappell MC. Does ACE2 contribute to the development of hypertension? Hypertens Res. 2010 Feb; 33(2):107-9.
    View in: PubMed
    Score: 0.323
  11. Gwathmey TM, Pendergrass KD, Reid SD, Rose JC, Diz DI, Chappell MC. Angiotensin-(1-7)-angiotensin-converting enzyme 2 attenuates reactive oxygen species formation to angiotensin II within the cell nucleus. Hypertension. 2010 Jan; 55(1):166-71.
    View in: PubMed
    Score: 0.322
  12. Shaltout HA, Figueroa JP, Rose JC, Diz DI, Chappell MC. Alterations in circulatory and renal angiotensin-converting enzyme and angiotensin-converting enzyme 2 in fetal programmed hypertension. Hypertension. 2009 Feb; 53(2):404-8.
    View in: PubMed
    Score: 0.300
  13. Garabelli PJ, Modrall JG, Penninger JM, Ferrario CM, Chappell MC. Distinct roles for angiotensin-converting enzyme 2 and carboxypeptidase A in the processing of angiotensins within the murine heart. Exp Physiol. 2008 May; 93(5):613-21.
    View in: PubMed
    Score: 0.286
  14. Chappell MC. Emerging evidence for a functional angiotensin-converting enzyme 2-angiotensin-(1-7)-MAS receptor axis: more than regulation of blood pressure? Hypertension. 2007 Oct; 50(4):596-9.
    View in: PubMed
    Score: 0.275
  15. Shaltout HA, Westwood BM, Averill DB, Ferrario CM, Figueroa JP, Diz DI, Rose JC, Chappell MC. Angiotensin metabolism in renal proximal tubules, urine, and serum of sheep: evidence for ACE2-dependent processing of angiotensin II. Am J Physiol Renal Physiol. 2007 Jan; 292(1):F82-91.
    View in: PubMed
    Score: 0.256
  16. Brosnihan KB, Neves LA, Chappell MC. Does the angiotensin-converting enzyme (ACE)/ACE2 balance contribute to the fate of angiotensin peptides in programmed hypertension? Hypertension. 2005 Nov; 46(5):1097-9.
    View in: PubMed
    Score: 0.241
  17. Modrall JG, Sadjadi J, Brosnihan KB, Gallagher PE, Yu CH, Kramer GL, Bernstein KE, Chappell MC. Depletion of tissue angiotensin-converting enzyme differentially influences the intrarenal and urinary expression of angiotensin peptides. Hypertension. 2004 Apr; 43(4):849-53.
    View in: PubMed
    Score: 0.216
  18. Sodhi CP, Wohlford-Lenane C, Yamaguchi Y, Prindle T, Fulton WB, Wang S, McCray PB, Chappell M, Hackam DJ, Jia H. Attenuation of pulmonary ACE2 activity impairs inactivation of des-Arg9 bradykinin/BKB1R axis and facilitates LPS-induced neutrophil infiltration. . 2018 01 01; 314(1):L17-L31.
    View in: PubMed
    Score: 0.138
  19. Wester A, Devocelle M, Tallant EA, Chappell MC, Gallagher PE, Paradisi F. Stabilization of Angiotensin-(1-7) by key substitution with a cyclic non-natural amino acid. Amino Acids. 2017 10; 49(10):1733-1742.
    View in: PubMed
    Score: 0.137
  20. Chen K, Bi J, Su Y, Chappell MC, Rose JC. Sex-Specific Changes in Renal Angiotensin-Converting Enzyme and Angiotensin-Converting Enzyme 2 Gene Expression and Enzyme Activity at Birth and Over the First Year of Life. Reprod Sci. 2016 Feb; 23(2):200-10.
    View in: PubMed
    Score: 0.119
  21. Chappell MC. Nonclassical renin-angiotensin system and renal function. Compr Physiol. 2012 Oct; 2(4):2733-52.
    View in: PubMed
    Score: 0.098
  22. Harrison-Bernard LM, Chappell MC. Unraveling the glomerular RAS: one peptidase at a time. Am J Physiol Renal Physiol. 2012 Aug 01; 303(3):F373-4.
    View in: PubMed
    Score: 0.095
  23. Bharadwaj MS, Strawn WB, Groban L, Yamaleyeva LM, Chappell MC, Horta C, Atkins K, Firmes L, Gurley SB, Brosnihan KB. Angiotensin-converting enzyme 2 deficiency is associated with impaired gestational weight gain and fetal growth restriction. Hypertension. 2011 Nov; 58(5):852-8.
    View in: PubMed
    Score: 0.091
  24. Gwathmey TM, Westwood BM, Pirro NT, Tang L, Rose JC, Diz DI, Chappell MC. Nuclear angiotensin-(1-7) receptor is functionally coupled to the formation of nitric oxide. Am J Physiol Renal Physiol. 2010 Nov; 299(5):F983-90.
    View in: PubMed
    Score: 0.085
  25. Arnold AC, Isa K, Shaltout HA, Nautiyal M, Ferrario CM, Chappell MC, Diz DI. Angiotensin-(1-12) requires angiotensin converting enzyme and AT1 receptors for cardiovascular actions within the solitary tract nucleus. . 2010 Sep; 299(3):H763-71.
    View in: PubMed
    Score: 0.084
  26. Trask AJ, Groban L, Westwood BM, Varagic J, Ganten D, Gallagher PE, Chappell MC, Ferrario CM. Inhibition of angiotensin-converting enzyme 2 exacerbates cardiac hypertrophy and fibrosis in Ren-2 hypertensive rats. Am J Hypertens. 2010 Jun; 23(6):687-93.
    View in: PubMed
    Score: 0.082
  27. Park S, Bivona BJ, Kobori H, Seth DM, Chappell MC, Lazartigues E, Harrison-Bernard LM. Major role for ACE-independent intrarenal ANG II formation in type II diabetes. Am J Physiol Renal Physiol. 2010 Jan; 298(1):F37-48.
    View in: PubMed
    Score: 0.080
  28. Jia HP, Look DC, Tan P, Shi L, Hickey M, Gakhar L, Chappell MC, Wohlford-Lenane C, McCray PB. Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia. . 2009 Jul; 297(1):L84-96.
    View in: PubMed
    Score: 0.077
  29. Diz DI, Garcia-Espinosa MA, Gegick S, Tommasi EN, Ferrario CM, Ann Tallant E, Chappell MC, Gallagher PE. Injections of angiotensin-converting enzyme 2 inhibitor MLN4760 into nucleus tractus solitarii reduce baroreceptor reflex sensitivity for heart rate control in rats. Exp Physiol. 2008 May; 93(5):694-700.
    View in: PubMed
    Score: 0.072
  30. Oudit GY, Kassiri Z, Patel MP, Chappell M, Butany J, Backx PH, Tsushima RG, Scholey JW, Khokha R, Penninger JM. Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice. Cardiovasc Res. 2007 Jul 01; 75(1):29-39.
    View in: PubMed
    Score: 0.067
  31. Trask AJ, Averill DB, Ganten D, Chappell MC, Ferrario CM. Primary role of angiotensin-converting enzyme-2 in cardiac production of angiotensin-(1-7) in transgenic Ren-2 hypertensive rats. . 2007 Jun; 292(6):H3019-24.
    View in: PubMed
    Score: 0.066
  32. Chappell MC, Yamaleyeva LM, Westwood BM. Estrogen and salt sensitivity in the female mRen(2). Lewis rat. . 2006 Nov; 291(5):R1557-63.
    View in: PubMed
    Score: 0.064
  33. Jessup JA, Gallagher PE, Averill DB, Brosnihan KB, Tallant EA, Chappell MC, Ferrario CM. Effect of angiotensin II blockade on a new congenic model of hypertension derived from transgenic Ren-2 rats. . 2006 Nov; 291(5):H2166-72.
    View in: PubMed
    Score: 0.063
  34. Ferrario CM, Jessup J, Gallagher PE, Averill DB, Brosnihan KB, Ann Tallant E, Smith RD, Chappell MC. Effects of renin-angiotensin system blockade on renal angiotensin-(1-7) forming enzymes and receptors. Kidney Int. 2005 Nov; 68(5):2189-96.
    View in: PubMed
    Score: 0.061
  35. Sadjadi J, Kramer GL, Yu CH, Burress Welborn M, Chappell MC, Gregory Modrall J. Angiotensin converting enzyme-independent angiotensin ii production by chymase is up-regulated in the ischemic kidney in renovascular hypertension. J Surg Res. 2005 Aug; 127(2):65-9.
    View in: PubMed
    Score: 0.060
  36. Chappell MC, Modrall JG, Diz DI, Ferrario CM. Novel aspects of the renal renin-angiotensin system: angiotensin-(1-7), ACE2 and blood pressure regulation. Contrib Nephrol. 2004; 143:77-89.
    View in: PubMed
    Score: 0.053
  37. Leung PS, Chappell MC. A local pancreatic renin-angiotensin system: endocrine and exocrine roles. Int J Biochem Cell Biol. 2003 Jun; 35(6):838-46.
    View in: PubMed
    Score: 0.051
  38. Crackower MA, Sarao R, Oudit GY, Yagil C, Kozieradzki I, Scanga SE, Oliveira-dos-Santos AJ, da Costa J, Zhang L, Pei Y, Scholey J, Ferrario CM, Manoukian AS, Chappell MC, Backx PH, Yagil Y, Penninger JM. Angiotensin-converting enzyme 2 is an essential regulator of heart function. Nature. 2002 Jun 20; 417(6891):822-8.
    View in: PubMed
    Score: 0.048
  39. Yamaleyeva LM, Chappell MC, Brosnihan KB, Anton L, Caudell DL, Shi S, McGee C, Pirro N, Gallagher PE, Taylor RN, Merrill DC, Mertz HL. Downregulation of apelin in the human placental chorionic villi from preeclamptic pregnancies. Am J Physiol Endocrinol Metab. 2015 Nov 15; 309(10):E852-60.
    View in: PubMed
    Score: 0.030
  40. Ahmad S, Simmons T, Varagic J, Moniwa N, Chappell MC, Ferrario CM. Chymase-dependent generation of angiotensin II from angiotensin-(1-12) in human atrial tissue. PLoS One. 2011; 6(12):e28501.
    View in: PubMed
    Score: 0.023
  41. Gilliam-Davis S, Gallagher PE, Payne VS, Kasper SO, Tommasi EN, Westwood BM, Robbins ME, Chappell MC, Diz DI. Long-term systemic angiotensin II type 1 receptor blockade regulates mRNA expression of dorsomedial medulla renin-angiotensin system components. Physiol Genomics. 2011 Jul 14; 43(13):829-35.
    View in: PubMed
    Score: 0.022
  42. Varagic J, Ahmad S, Brosnihan KB, Groban L, Chappell MC, Tallant EA, Gallagher PE, Ferrario CM. Decreased cardiac Ang-(1-7) is associated with salt-induced cardiac remodeling and dysfunction. Ther Adv Cardiovasc Dis. 2010 Feb; 4(1):17-25.
    View in: PubMed
    Score: 0.020
  43. Gallagher PE, Chappell MC, Ferrario CM, Tallant EA. Distinct roles for ANG II and ANG-(1-7) in the regulation of angiotensin-converting enzyme 2 in rat astrocytes. . 2006 Feb; 290(2):C420-6.
    View in: PubMed
    Score: 0.015
  44. Kuba K, Imai Y, Rao S, Gao H, Guo F, Guan B, Huan Y, Yang P, Zhang Y, Deng W, Bao L, Zhang B, Liu G, Wang Z, Chappell M, Liu Y, Zheng D, Leibbrandt A, Wada T, Slutsky AS, Liu D, Qin C, Jiang C, Penninger JM. A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury. Nat Med. 2005 Aug; 11(8):875-9.
    View in: PubMed
    Score: 0.015
  45. Ferrario CM, Jessup J, Chappell MC, Averill DB, Brosnihan KB, Tallant EA, Diz DI, Gallagher PE. Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2. Circulation. 2005 May 24; 111(20):2605-10.
    View in: PubMed
    Score: 0.015
  46. Brosnihan KB, Neves LA, Joyner J, Averill DB, Chappell MC, Sarao R, Penninger J, Ferrario CM. Enhanced renal immunocytochemical expression of ANG-(1-7) and ACE2 during pregnancy. Hypertension. 2003 Oct; 42(4):749-53.
    View in: PubMed
    Score: 0.013
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Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.