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Connection

Martha Alexander-Miller to Animals

This is a "connection" page, showing publications Martha Alexander-Miller has written about Animals.
Connection Strength

2.122
  1. Shultz PK, Crofts KF, Holbrook BC, Alexander-Miller MA. Neuraminidase-specific antibody responses are generated in naive and vaccinated newborn nonhuman primates following virus infection. JCI Insight. 2020 12 17; 5(24).
    View in: PubMed
    Score: 0.081
  2. Alexander-Miller MA. Challenges for the Newborn Following Influenza Virus Infection and Prospects for an Effective Vaccine. Front Immunol. 2020; 11:568651.
    View in: PubMed
    Score: 0.080
  3. Holbrook BC, Alexander-Miller MA. Higher Frequency and Increased Expression of Molecules Associated with Suppression on T Regulatory Cells from Newborn Compared with Adult Nonhuman Primates. J Immunol. 2020 10 15; 205(8):2128-2136.
    View in: PubMed
    Score: 0.079
  4. Crofts KF, Holbrook BC, Soto-Pantoja DR, Ornelles DA, Alexander-Miller MA. TCR Dependent Metabolic Programming Regulates Autocrine IL-4 Production Resulting in Self-Tuning of the CD8+ T Cell Activation Setpoint. Front Immunol. 2020; 11:540.
    View in: PubMed
    Score: 0.077
  5. Westcott MM, Clemens EA, Holbrook BC, King SB, Alexander-Miller MA. The choice of linker for conjugating R848 to inactivated influenza virus determines the stimulatory capacity for innate immune cells. Vaccine. 2018 02 21; 36(9):1174-1182.
    View in: PubMed
    Score: 0.067
  6. Holbrook BC, Aycock ST, Machiele E, Clemens E, Gries D, Jorgensen MJ, Hadimani MB, King SB, Alexander-Miller MA. An R848 adjuvanted influenza vaccine promotes early activation of B cells in the draining lymph nodes of non-human primate neonates. Immunology. 2018 03; 153(3):357-367.
    View in: PubMed
    Score: 0.065
  7. Holbrook BC, D'Agostino RB, Tyler Aycock S, Jorgensen MJ, Hadimani MB, Bruce King S, Alexander-Miller MA. Adjuvanting an inactivated influenza vaccine with conjugated R848 improves the level of antibody present at 6months in a nonhuman primate neonate model. Vaccine. 2017 10 27; 35(45):6137-6142.
    View in: PubMed
    Score: 0.065
  8. Holbrook BC, D'Agostino RB, Parks GD, Alexander-Miller MA. Adjuvanting an inactivated influenza vaccine with flagellin improves the function and quantity of the long-term antibody response in a nonhuman primate neonate model. Vaccine. 2016 09 07; 34(39):4712-4717.
    View in: PubMed
    Score: 0.060
  9. Holbrook BC, Kim JR, Blevins LK, Jorgensen MJ, Kock ND, D'Agostino RB, Aycock ST, Hadimani MB, King SB, Parks GD, Alexander-Miller MA. A Novel R848-Conjugated Inactivated Influenza Virus Vaccine Is Efficacious and Safe in a Neonate Nonhuman Primate Model. J Immunol. 2016 07 15; 197(2):555-64.
    View in: PubMed
    Score: 0.059
  10. Kim JR, Holbrook BC, Hayward SL, Blevins LK, Jorgensen MJ, Kock ND, De Paris K, D'Agostino RB, Aycock ST, Mizel SB, Parks GD, Alexander-Miller MA. Inclusion of Flagellin during Vaccination against Influenza Enhances Recall Responses in Nonhuman Primate Neonates. J Virol. 2015 Jul; 89(14):7291-303.
    View in: PubMed
    Score: 0.055
  11. Holbrook BC, Hayward SL, Blevins LK, Kock N, Aycock T, Parks GD, Alexander-Miller MA. Nonhuman primate infants have an impaired respiratory but not systemic IgG antibody response following influenza virus infection. Virology. 2015 Feb; 476:124-133.
    View in: PubMed
    Score: 0.054
  12. Alexander-Miller MA. Vaccines against respiratory viral pathogens for use in neonates: opportunities and challenges. J Immunol. 2014 Dec 01; 193(11):5363-9.
    View in: PubMed
    Score: 0.053
  13. Blevins LK, Wren JT, Holbrook BC, Hayward SL, Swords WE, Parks GD, Alexander-Miller MA. Coinfection with Streptococcus pneumoniae negatively modulates the size and composition of the ongoing influenza-specific CD8? T cell response. J Immunol. 2014 Nov 15; 193(10):5076-87.
    View in: PubMed
    Score: 0.053
  14. Shiner EK, Holbrook BC, Alexander-Miller MA. CD4+ T cell subset differentiation and avidity setpoint are dictated by the interplay of cytokine and antigen mediated signals. PLoS One. 2014; 9(6):e100175.
    View in: PubMed
    Score: 0.052
  15. Parks GD, Alexander-Miller MA. Paramyxovirus activation and inhibition of innate immune responses. J Mol Biol. 2013 Dec 13; 425(24):4872-92.
    View in: PubMed
    Score: 0.049
  16. Holbrook BC, Yammani RD, Blevins LK, Alexander-Miller MA. In vivo modulation of avidity in highly sensitive CD8(+) effector T cells following viral infection. Viral Immunol. 2013 Oct; 26(5):302-13.
    View in: PubMed
    Score: 0.049
  17. Amoah S, Holbrook BC, Yammani RD, Alexander-Miller MA. High viral burden restricts short-lived effector cell number at late times postinfection through increased natural regulatory T cell expansion. J Immunol. 2013 May 15; 190(10):5020-9.
    View in: PubMed
    Score: 0.048
  18. Beauchamp NM, Yammani RD, Alexander-Miller MA. CD8 marks a subpopulation of lung-derived dendritic cells with differential responsiveness to viral infection and toll-like receptor stimulation. J Virol. 2012 Oct; 86(19):10640-50.
    View in: PubMed
    Score: 0.045
  19. Amoah S, Yammani RD, Grayson JM, Alexander-Miller MA. Changes in functional but not structural avidity during differentiation of CD8+ effector cells in vivo after virus infection. J Immunol. 2012 Jul 15; 189(2):638-45.
    View in: PubMed
    Score: 0.045
  20. Sharma SK, Alexander-Miller MA. Increased sensitivity to antigen in high avidity CD8(+) T cells results from augmented membrane proximal T-cell receptor signal transduction. Immunology. 2011 Jul; 133(3):307-17.
    View in: PubMed
    Score: 0.041
  21. Busick RY, Yammani RD, Alexander-Miller MA. Differentiation-dependent differences in murine T cell susceptibility to negative regulation by the lung. Am J Respir Cell Mol Biol. 2011 May; 44(5):597-605.
    View in: PubMed
    Score: 0.041
  22. Palmer EM, Holbrook BC, Arimilli S, Parks GD, Alexander-Miller MA. IFNgamma-producing, virus-specific CD8+ effector cells acquire the ability to produce IL-10 as a result of entry into the infected lung environment. Virology. 2010 Sep 01; 404(2):225-30.
    View in: PubMed
    Score: 0.040
  23. Beauchamp NM, Busick RY, Alexander-Miller MA. Functional divergence among CD103+ dendritic cell subpopulations following pulmonary poxvirus infection. J Virol. 2010 Oct; 84(19):10191-9.
    View in: PubMed
    Score: 0.039
  24. Arimilli S, Sharma SK, Yammani R, Reid SD, Parks GD, Alexander-Miller MA. Pivotal Advance: Nonfunctional lung effectors exhibit decreased calcium mobilization associated with reduced expression of ORAI1. J Leukoc Biol. 2010 Jun; 87(6):977-88.
    View in: PubMed
    Score: 0.038
  25. Yates NL, Yammani RD, Alexander-Miller MA. Dose-dependent lymphocyte apoptosis following respiratory infection with Vaccinia virus. Virus Res. 2008 Nov; 137(2):198-205.
    View in: PubMed
    Score: 0.035
  26. Yammani RD, Pejawar-Gaddy S, Gurley TC, Weimer ET, Hiltbold EM, Alexander-Miller MA. Regulation of maturation and activating potential in CD8+ versus CD8- dendritic cells following in vivo infection with vaccinia virus. Virology. 2008 Aug 15; 378(1):142-50.
    View in: PubMed
    Score: 0.034
  27. Kroger CJ, Amoah S, Alexander-Miller MA. Cutting edge: Dendritic cells prime a high avidity CTL response independent of the level of presented antigen. J Immunol. 2008 May 01; 180(9):5784-8.
    View in: PubMed
    Score: 0.034
  28. Arimilli S, Palmer EM, Alexander-Miller MA. Loss of function in virus-specific lung effector T cells is independent of infection. J Leukoc Biol. 2008 Mar; 83(3):564-74.
    View in: PubMed
    Score: 0.033
  29. Kroger CJ, Alexander-Miller MA. Cutting edge: CD8+ T cell clones possess the potential to differentiate into both high- and low-avidity effector cells. J Immunol. 2007 Jul 15; 179(2):748-51.
    View in: PubMed
    Score: 0.032
  30. Kroger CJ, Alexander-Miller MA. Dose-dependent modulation of CD8 and functional avidity as a result of peptide encounter. Immunology. 2007 Oct; 122(2):167-78.
    View in: PubMed
    Score: 0.032
  31. Pejawar-Gaddy S, Gitiban-Vaghefi N, Parks GD, Alexander-Miller MA. Distinct pathways for signaling maturation in macrophages and dendritic cells after infection with paramyxovirus simian virus 5. Viral Immunol. 2007; 20(1):76-87.
    View in: PubMed
    Score: 0.031
  32. Yates NL, Alexander-Miller MA. Vaccinia virus infection of mature dendritic cells results in activation of virus-specific naïve CD8+ T cells: a potential mechanism for direct presentation. Virology. 2007 Mar 15; 359(2):349-61.
    View in: PubMed
    Score: 0.030
  33. Pejawar-Gaddy S, Alexander-Miller MA. Ligation of CD80 is critical for high-level CD25 expression on CD8+ T lymphocytes. J Immunol. 2006 Oct 01; 177(7):4495-502.
    View in: PubMed
    Score: 0.030
  34. Pejawar SS, Parks GD, Alexander-Miller MA. Abortive versus productive viral infection of dendritic cells with a paramyxovirus results in differential upregulation of select costimulatory molecules. J Virol. 2005 Jun; 79(12):7544-57.
    View in: PubMed
    Score: 0.028
  35. Gray PM, Arimilli S, Palmer EM, Parks GD, Alexander-Miller MA. Altered function in CD8+ T cells following paramyxovirus infection of the respiratory tract. J Virol. 2005 Mar; 79(6):3339-49.
    View in: PubMed
    Score: 0.027
  36. Gray PM, Parks GD, Alexander-Miller MA. Modulation of CD8+ T cell avidity by increasing the turnover of viral antigen during infection. Cell Immunol. 2004 Sep-Oct; 231(1-2):14-9.
    View in: PubMed
    Score: 0.027
  37. Alexander-Miller MA. High-avidity CD8+ T cells: optimal soldiers in the war against viruses and tumors. Immunol Res. 2005; 31(1):13-24.
    View in: PubMed
    Score: 0.027
  38. Cawthon AG, Kroger CJ, Alexander-Miller MA. High avidity CD8+ T cells generated from CD28-deficient or wildtype mice exhibit a differential dependence on lipid raft integrity for activation. Cell Immunol. 2004 Feb; 227(2):148-55.
    View in: PubMed
    Score: 0.025
  39. Gray PM, Parks GD, Alexander-Miller MA. High avidity CD8+ T cells are the initial population elicited following viral infection of the respiratory tract. J Immunol. 2003 Jan 01; 170(1):174-81.
    View in: PubMed
    Score: 0.023
  40. Stirling ER, Terabe M, Wilson AS, Kooshki M, Yamaleyeva LM, Alexander-Miller MA, Zhang W, Miller LD, Triozzi PL, Soto-Pantoja DR. Targeting the CD47/thrombospondin-1 signaling axis regulates immune cell bioenergetics in the tumor microenvironment to potentiate antitumor immune response. J Immunother Cancer. 2022 Nov; 10(11).
    View in: PubMed
    Score: 0.023
  41. Cawthon AG, Alexander-Miller MA. Optimal colocalization of TCR and CD8 as a novel mechanism for the control of functional avidity. J Immunol. 2002 Oct 01; 169(7):3492-8.
    View in: PubMed
    Score: 0.023
  42. Parks GD, Alexander-Miller MA. High avidity cytotoxic T lymphocytes to a foreign antigen are efficiently activated following immunization with a recombinant paramyxovirus, simian virus 5. J Gen Virol. 2002 May; 83(Pt 5):1167-1172.
    View in: PubMed
    Score: 0.022
  43. Gray PM, Parks GD, Alexander-Miller MA. A novel CD8-independent high-avidity cytotoxic T-lymphocyte response directed against an epitope in the phosphoprotein of the paramyxovirus simian virus 5. J Virol. 2001 Nov; 75(21):10065-72.
    View in: PubMed
    Score: 0.022
  44. Cawthon AG, Lu H, Alexander-Miller MA. Peptide requirement for CTL activation reflects the sensitivity to CD3 engagement: correlation with CD8alphabeta versus CD8alphaalpha expression. J Immunol. 2001 Sep 01; 167(5):2577-84.
    View in: PubMed
    Score: 0.021
  45. Alexander-Miller MA. Differential expansion and survival of high and low avidity cytotoxic T cell populations during the immune response to a viral infection. Cell Immunol. 2000 Apr 10; 201(1):58-62.
    View in: PubMed
    Score: 0.019
  46. Alexander-Miller MA, Derby MA, Sarin A, Henkart PA, Berzofsky JA. Supraoptimal peptide-major histocompatibility complex causes a decrease in bc1-2 levels and allows tumor necrosis factor alpha receptor II-mediated apoptosis of cytotoxic T lymphocytes. J Exp Med. 1998 Oct 19; 188(8):1391-9.
    View in: PubMed
    Score: 0.017
  47. Martin AN, Alexander-Miller M, Yoza BK, Vachharajani V, McCall CE. Sirtuin1 Targeting Reverses Innate and Adaptive Immune Tolerance in Septic Mice. J Immunol Res. 2018; 2018:2402593.
    View in: PubMed
    Score: 0.017
  48. Wajih N, Basu S, Jailwala A, Kim HW, Ostrowski D, Perlegas A, Bolden CA, Buechler NL, Gladwin MT, Caudell DL, Rahbar E, Alexander-Miller MA, Vachharajani V, Kim-Shapiro DB. Potential therapeutic action of nitrite in sickle cell disease. Redox Biol. 2017 08; 12:1026-1039.
    View in: PubMed
    Score: 0.016
  49. Wren JT, Blevins LK, Pang B, Basu Roy A, Oliver MB, Reimche JL, Wozniak JE, Alexander-Miller MA, Swords WE. Pneumococcal Neuraminidase A (NanA) Promotes Biofilm Formation and Synergizes with Influenza A Virus in Nasal Colonization and Middle Ear Infection. Infect Immun. 2017 04; 85(4).
    View in: PubMed
    Score: 0.016
  50. Shewale SV, Brown AL, Bi X, Boudyguina E, Sawyer JK, Alexander-Miller MA, Parks JS. In vivo activation of leukocyte GPR120/FFAR4 by PUFAs has minimal impact on atherosclerosis in LDL receptor knockout mice. J Lipid Res. 2017 01; 58(1):236-246.
    View in: PubMed
    Score: 0.015
  51. Alexander-Miller MA, Leggatt GR, Sarin A, Berzofsky JA. Role of antigen, CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL. J Exp Med. 1996 Aug 01; 184(2):485-92.
    View in: PubMed
    Score: 0.015
  52. Alexander-Miller MA, Leggatt GR, Berzofsky JA. Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy. Proc Natl Acad Sci U S A. 1996 Apr 30; 93(9):4102-7.
    View in: PubMed
    Score: 0.015
  53. Wren JT, Blevins LK, Pang B, King LB, Perez AC, Murrah KA, Reimche JL, Alexander-Miller MA, Swords WE. Influenza A virus alters pneumococcal nasal colonization and middle ear infection independently of phase variation. Infect Immun. 2014 Nov; 82(11):4802-12.
    View in: PubMed
    Score: 0.013
  54. Alexander-Miller MA, Burke K, Koszinowski UH, Hansen TH, Connolly JM. Alloreactive cytotoxic T lymphocytes generated in the presence of viral-derived peptides show exquisite peptide and MHC specificity. J Immunol. 1993 Jul 01; 151(1):1-10.
    View in: PubMed
    Score: 0.012
  55. Brown AL, Zhu X, Rong S, Shewale S, Seo J, Boudyguina E, Gebre AK, Alexander-Miller MA, Parks JS. Omega-3 fatty acids ameliorate atherosclerosis by favorably altering monocyte subsets and limiting monocyte recruitment to aortic lesions. Arterioscler Thromb Vasc Biol. 2012 Sep; 32(9):2122-30.
    View in: PubMed
    Score: 0.011
  56. Johnson JB, Lyles DS, Alexander-Miller MA, Parks GD. Virion-associated complement regulator CD55 is more potent than CD46 in mediating resistance of mumps virus and vesicular stomatitis virus to neutralization. J Virol. 2012 Sep; 86(18):9929-40.
    View in: PubMed
    Score: 0.011
  57. Alexander MA, Damico CA, Wieties KM, Hansen TH, Connolly JM. Correlation between CD8 dependency and determinant density using peptide-induced, Ld-restricted cytotoxic T lymphocytes. J Exp Med. 1991 Apr 01; 173(4):849-58.
    View in: PubMed
    Score: 0.010
  58. Hicks AM, Riedlinger G, Willingham MC, Alexander-Miller MA, Von Kap-Herr C, Pettenati MJ, Sanders AM, Weir HM, Du W, Kim J, Simpson AJ, Old LJ, Cui Z. Transferable anticancer innate immunity in spontaneous regression/complete resistance mice. Proc Natl Acad Sci U S A. 2006 May 16; 103(20):7753-8.
    View in: PubMed
    Score: 0.007
  59. Cui Z, Willingham MC, Hicks AM, Alexander-Miller MA, Howard TD, Hawkins GA, Miller MS, Weir HM, Du W, DeLong CJ. Spontaneous regression of advanced cancer: identification of a unique genetically determined, age-dependent trait in mice. Proc Natl Acad Sci U S A. 2003 May 27; 100(11):6682-7.
    View in: PubMed
    Score: 0.006
  60. Spolski RJ, Alexander-Miller MA, Kuhn RE. Suppressed cytotoxic T lymphocyte responses in experimental cysticercosis. Vet Parasitol. 2002 Jul 02; 106(4):325-30.
    View in: PubMed
    Score: 0.006
  61. Derby MA, Snyder JT, Tse R, Alexander-Miller MA, Berzofsky JA. An abrupt and concordant initiation of apoptosis: antigen-dependent death of CD8+ CTL. Eur J Immunol. 2001 Oct; 31(10):2951-9.
    View in: PubMed
    Score: 0.005
  62. Leggatt GR, Alexander-Miller MA, Kumar A, Hoffman SL, Berzofsky JA. Cytotoxic T lymphocyte (CTL) adherence assay (CAA): a non-radioactive assay for murine CTL recognition of peptide-MHC class I complexes. J Immunol Methods. 1997 Feb 14; 201(1):1-10.
    View in: PubMed
    Score: 0.004
  63. Sarin A, Williams MS, Alexander-Miller MA, Berzofsky JA, Zacharchuk CM, Henkart PA. Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases. Immunity. 1997 Feb; 6(2):209-15.
    View in: PubMed
    Score: 0.004
  64. Goss JA, Alexander-Miller MA, Gorka J, Flye MW, Connolly JM, Hansen TH. Specific prolongation of allograft survival by a T-cell-receptor-derived peptide. Proc Natl Acad Sci U S A. 1993 Nov 01; 90(21):9872-6.
    View in: PubMed
    Score: 0.003
  65. Solheim JC, Alexander-Miller MA, Martinko JM, Connolly JM. Biased T cell receptor usage by Ld-restricted, tum- peptide-specific cytotoxic T lymphocyte clones. J Immunol. 1993 Feb 01; 150(3):800-11.
    View in: PubMed
    Score: 0.003
  66. Nuñez G, London L, Hockenbery D, Alexander M, McKearn JP, Korsmeyer SJ. Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines. J Immunol. 1990 May 01; 144(9):3602-10.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.