Leslie Poole to Peroxiredoxins
This is a "connection" page, showing publications Leslie Poole has written about Peroxiredoxins.
Connection Strength
9.141
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Al-Barakati H, Newman RH, Kc DB, Poole LB. Bioinformatic Analyses of Peroxiredoxins and RF-Prx: A Random Forest-Based Predictor and Classifier for Prxs. Methods Mol Biol. 2022; 2499:155-176.
Score: 0.770
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Nelson KJ, Perkins A, Van Swearingen AED, Hartman S, Brereton AE, Parsonage D, Salsbury FR, Karplus PA, Poole LB. Experimentally Dissecting the Origins of Peroxiredoxin Catalysis. Antioxid Redox Signal. 2018 Mar 01; 28(7):521-536.
Score: 0.554
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Poole LB, Nelson KJ. Distribution and Features of the Six Classes of Peroxiredoxins. Mol Cells. 2016 Jan; 39(1):53-9.
Score: 0.510
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Parsonage D, Nelson KJ, Ferrer-Sueta G, Alley S, Karplus PA, Furdui CM, Poole LB. Dissecting peroxiredoxin catalysis: separating binding, peroxidation, and resolution for a bacterial AhpC. Biochemistry. 2015 Feb 24; 54(7):1567-75.
Score: 0.478
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Nelson KJ, Parsonage D, Karplus PA, Poole LB. Evaluating peroxiredoxin sensitivity toward inactivation by peroxide substrates. Methods Enzymol. 2013; 527:21-40.
Score: 0.413
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Karplus PA, Poole LB. Peroxiredoxins as molecular triage agents, sacrificing themselves to enhance cell survival during a peroxide attack. Mol Cell. 2012 Feb 10; 45(3):275-8.
Score: 0.388
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Reeves SA, Parsonage D, Nelson KJ, Poole LB. Kinetic and thermodynamic features reveal that Escherichia coli BCP is an unusually versatile peroxiredoxin. Biochemistry. 2011 Oct 18; 50(41):8970-81.
Score: 0.378
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Poole LB, Hall A, Nelson KJ. Overview of peroxiredoxins in oxidant defense and redox regulation. Curr Protoc Toxicol. 2011 Aug; Chapter 7:Unit7.9.
Score: 0.374
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Parsonage D, Desrosiers DC, Hazlett KR, Sun Y, Nelson KJ, Cox DL, Radolf JD, Poole LB. Broad specificity AhpC-like peroxiredoxin and its thioredoxin reductant in the sparse antioxidant defense system of Treponema pallidum. Proc Natl Acad Sci U S A. 2010 Apr 06; 107(14):6240-5.
Score: 0.340
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Hall A, Karplus PA, Poole LB. Typical 2-Cys peroxiredoxins--structures, mechanisms and functions. FEBS J. 2009 May; 276(9):2469-77.
Score: 0.318
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Nelson KJ, Parsonage D, Hall A, Karplus PA, Poole LB. Cysteine pK(a) values for the bacterial peroxiredoxin AhpC. Biochemistry. 2008 Dec 02; 47(48):12860-8.
Score: 0.311
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Yamamoto Y, Ritz D, Planson AG, Jönsson TJ, Faulkner MJ, Boyd D, Beckwith J, Poole LB. Mutant AhpC peroxiredoxins suppress thiol-disulfide redox deficiencies and acquire deglutathionylating activity. Mol Cell. 2008 Jan 18; 29(1):36-45.
Score: 0.293
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Parsonage D, Karplus PA, Poole LB. Substrate specificity and redox potential of AhpC, a bacterial peroxiredoxin. Proc Natl Acad Sci U S A. 2008 Jun 17; 105(24):8209-14.
Score: 0.292
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Poole LB. The catalytic mechanism of peroxiredoxins. Subcell Biochem. 2007; 44:61-81.
Score: 0.272
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Estelle AB, Reardon PN, Pinckney SH, Poole LB, Barbar E, Karplus PA. Native state fluctuations in a peroxiredoxin active site match motions needed for catalysis. Structure. 2022 02 03; 30(2):278-288.e3.
Score: 0.190
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Randall LM, Dalla Rizza J, Parsonage D, Santos J, Mehl RA, Lowther WT, Poole LB, Denicola A. Unraveling the effects of peroxiredoxin 2 nitration; role of C-terminal tyrosine 193. Free Radic Biol Med. 2019 09; 141:492-501.
Score: 0.162
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Teixeira F, Tse E, Castro H, Makepeace KAT, Meinen BA, Borchers CH, Poole LB, Bardwell JC, Tomás AM, Southworth DR, Jakob U. Chaperone activation and client binding of a 2-cysteine peroxiredoxin. Nat Commun. 2019 02 08; 10(1):659.
Score: 0.157
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Bolduc JA, Nelson KJ, Haynes AC, Lee J, Reisz JA, Graff AH, Clodfelter JE, Parsonage D, Poole LB, Furdui CM, Lowther WT. Novel hyperoxidation resistance motifs in 2-Cys peroxiredoxins. J Biol Chem. 2018 07 27; 293(30):11901-11912.
Score: 0.150
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Portillo-Ledesma S, Randall LM, Parsonage D, Dalla Rizza J, Karplus PA, Poole LB, Denicola A, Ferrer-Sueta G. Differential Kinetics of Two-Cysteine Peroxiredoxin Disulfide Formation Reveal a Novel Model for Peroxide Sensing. Biochemistry. 2018 06 19; 57(24):3416-3424.
Score: 0.148
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Harper AF, Leuthaeuser JB, Babbitt PC, Morris JH, Ferrin TE, Poole LB, Fetrow JS. An Atlas of Peroxiredoxins Created Using an Active Site Profile-Based Approach to Functionally Relevant Clustering of Proteins. PLoS Comput Biol. 2017 02; 13(2):e1005284.
Score: 0.137
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Perkins A, Parsonage D, Nelson KJ, Ogba OM, Cheong PH, Poole LB, Karplus PA. Peroxiredoxin Catalysis at Atomic Resolution. Structure. 2016 Oct 04; 24(10):1668-1678.
Score: 0.133
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Buchko GW, Perkins A, Parsonage D, Poole LB, Karplus PA. Backbone chemical shift assignments for Xanthomonas campestris peroxiredoxin Q in the reduced and oxidized states: a dramatic change in backbone dynamics. Biomol NMR Assign. 2016 Apr; 10(1):57-61.
Score: 0.124
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Perkins A, Nelson KJ, Parsonage D, Poole LB, Karplus PA. Peroxiredoxins: guardians against oxidative stress and modulators of peroxide signaling. Trends Biochem Sci. 2015 Aug; 40(8):435-45.
Score: 0.122
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Perkins A, Poole LB, Karplus PA. Tuning of peroxiredoxin catalysis for various physiological roles. Biochemistry. 2014 Dec 16; 53(49):7693-705.
Score: 0.118
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Perkins A, Nelson KJ, Williams JR, Parsonage D, Poole LB, Karplus PA. The sensitive balance between the fully folded and locally unfolded conformations of a model peroxiredoxin. Biochemistry. 2013 Dec 03; 52(48):8708-21.
Score: 0.110
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Michalek RD, Crump KE, Weant AE, Hiltbold EM, Juneau DG, Moon EY, Yu DY, Poole LB, Grayson JM. Peroxiredoxin II regulates effector and secondary memory CD8+ T cell responses. J Virol. 2012 Dec; 86(24):13629-41.
Score: 0.102
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Perkins A, Gretes MC, Nelson KJ, Poole LB, Karplus PA. Mapping the active site helix-to-strand conversion of CxxxxC peroxiredoxin Q enzymes. Biochemistry. 2012 Sep 25; 51(38):7638-50.
Score: 0.101
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Salsbury FR, Yuan Y, Knaggs MH, Poole LB, Fetrow JS. Structural and electrostatic asymmetry at the active site in typical and atypical peroxiredoxin dimers. J Phys Chem B. 2012 Jun 14; 116(23):6832-43.
Score: 0.098
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Cho SH, Parsonage D, Thurston C, Dutton RJ, Poole LB, Collet JF, Beckwith J. A new family of membrane electron transporters and its substrates, including a new cell envelope peroxiredoxin, reveal a broadened reductive capacity of the oxidative bacterial cell envelope. mBio. 2012; 3(2).
Score: 0.098
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Gretes MC, Poole LB, Karplus PA. Peroxiredoxins in parasites. Antioxid Redox Signal. 2012 Aug 15; 17(4):608-33.
Score: 0.097
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Clarke TE, Romanov V, Chirgadze YN, Klomsiri C, Kisselman G, Wu-Brown J, Poole LB, Pai EF, Chirgadze NY. Crystal structure of alkyl hydroperoxidase D like protein PA0269 from Pseudomonas aeruginosa: homology of the AhpD-like structural family. BMC Struct Biol. 2011 May 26; 11:27.
Score: 0.092
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Hall A, Nelson K, Poole LB, Karplus PA. Structure-based insights into the catalytic power and conformational dexterity of peroxiredoxins. Antioxid Redox Signal. 2011 Aug 01; 15(3):795-815.
Score: 0.092
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Nelson KJ, Knutson ST, Soito L, Klomsiri C, Poole LB, Fetrow JS. Analysis of the peroxiredoxin family: using active-site structure and sequence information for global classification and residue analysis. Proteins. 2011 Mar; 79(3):947-64.
Score: 0.090
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Soito L, Williamson C, Knutson ST, Fetrow JS, Poole LB, Nelson KJ. PREX: PeroxiRedoxin classification indEX, a database of subfamily assignments across the diverse peroxiredoxin family. Nucleic Acids Res. 2011 Jan; 39(Database issue):D332-7.
Score: 0.089
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Klomsiri C, Karplus PA, Poole LB. Cysteine-based redox switches in enzymes. Antioxid Redox Signal. 2011 Mar 15; 14(6):1065-77.
Score: 0.088
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Hall A, Parsonage D, Poole LB, Karplus PA. Structural evidence that peroxiredoxin catalytic power is based on transition-state stabilization. J Mol Biol. 2010 Sep 10; 402(1):194-209.
Score: 0.087
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Bechtold E, Reisz JA, Klomsiri C, Tsang AW, Wright MW, Poole LB, Furdui CM, King SB. Water-soluble triarylphosphines as biomarkers for protein S-nitrosation. ACS Chem Biol. 2010 Apr 16; 5(4):405-14.
Score: 0.085
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Smith-Pearson PS, Kooshki M, Spitz DR, Poole LB, Zhao W, Robbins ME. Decreasing peroxiredoxin II expression decreases glutathione, alters cell cycle distribution, and sensitizes glioma cells to ionizing radiation and H(2)O(2). Free Radic Biol Med. 2008 Oct 15; 45(8):1178-89.
Score: 0.076
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Poole LB, Nelson KJ. Discovering mechanisms of signaling-mediated cysteine oxidation. Curr Opin Chem Biol. 2008 Feb; 12(1):18-24.
Score: 0.074
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Jönsson TJ, Ellis HR, Poole LB. Cysteine reactivity and thiol-disulfide interchange pathways in AhpF and AhpC of the bacterial alkyl hydroperoxide reductase system. Biochemistry. 2007 May 15; 46(19):5709-21.
Score: 0.069
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Parsonage D, Youngblood DS, Sarma GN, Wood ZA, Karplus PA, Poole LB. Analysis of the link between enzymatic activity and oligomeric state in AhpC, a bacterial peroxiredoxin. Biochemistry. 2005 Aug 09; 44(31):10583-92.
Score: 0.062
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Baker LM, Poole LB. Catalytic mechanism of thiol peroxidase from Escherichia coli. Sulfenic acid formation and overoxidation of essential CYS61. J Biol Chem. 2003 Mar 14; 278(11):9203-11.
Score: 0.052
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Wood ZA, Schröder E, Robin Harris J, Poole LB. Structure, mechanism and regulation of peroxiredoxins. Trends Biochem Sci. 2003 Jan; 28(1):32-40.
Score: 0.052
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Reynolds CM, Meyer J, Poole LB. An NADH-dependent bacterial thioredoxin reductase-like protein in conjunction with a glutaredoxin homologue form a unique peroxiredoxin (AhpC) reducing system in Clostridium pasteurianum. Biochemistry. 2002 Feb 12; 41(6):1990-2001.
Score: 0.049
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Poole LB, Ellis HR. Identification of cysteine sulfenic acid in AhpC of alkyl hydroperoxide reductase. Methods Enzymol. 2002; 348:122-36.
Score: 0.048
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Reynolds CM, Poole LB. Activity of one of two engineered heterodimers of AhpF, the NADH:peroxiredoxin oxidoreductase from Salmonella typhimurium, reveals intrasubunit electron transfer between domains. Biochemistry. 2001 Apr 3; 40(13):3912-9.
Score: 0.046
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Baker LM, Raudonikiene A, Hoffman PS, Poole LB. Essential thioredoxin-dependent peroxiredoxin system from Helicobacter pylori: genetic and kinetic characterization. J Bacteriol. 2001 Mar; 183(6):1961-73.
Score: 0.045
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Poole LB, Reynolds CM, Wood ZA, Karplus PA, Ellis HR, Li Calzi M. AhpF and other NADH:peroxiredoxin oxidoreductases, homologues of low Mr thioredoxin reductase. Eur J Biochem. 2000 Oct; 267(20):6126-33.
Score: 0.044
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Reynolds CM, Poole LB. Attachment of the N-terminal domain of Salmonella typhimurium AhpF to Escherichia coli thioredoxin reductase confers AhpC reductase activity but does not affect thioredoxin reductase activity. Biochemistry. 2000 Aug 1; 39(30):8859-69.
Score: 0.044
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Poole LB, Godzik A, Nayeem A, Schmitt JD. AhpF can be dissected into two functional units: tandem repeats of two thioredoxin-like folds in the N-terminus mediate electron transfer from the thioredoxin reductase-like C-terminus to AhpC. Biochemistry. 2000 Jun 6; 39(22):6602-15.
Score: 0.043
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Hall A, Parsonage D, Horita D, Karplus PA, Poole LB, Barbar E. Redox-dependent dynamics of a dual thioredoxin fold protein: evolution of specialized folds. Biochemistry. 2009 Jun 30; 48(25):5984-93.
Score: 0.020
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Phalen TJ, Weirather K, Deming PB, Anathy V, Howe AK, van der Vliet A, Jönsson TJ, Poole LB, Heintz NH. Oxidation state governs structural transitions in peroxiredoxin II that correlate with cell cycle arrest and recovery. J Cell Biol. 2006 Dec 04; 175(5):779-89.
Score: 0.017
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Jönsson TJ, Murray MS, Johnson LC, Poole LB, Lowther WT. Structural basis for the retroreduction of inactivated peroxiredoxins by human sulfiredoxin. Biochemistry. 2005 Jun 21; 44(24):8634-42.
Score: 0.015
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Wood ZA, Poole LB, Karplus PA. Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling. Science. 2003 Apr 25; 300(5619):650-3.
Score: 0.013
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Wood ZA, Poole LB, Hantgan RR, Karplus PA. Dimers to doughnuts: redox-sensitive oligomerization of 2-cysteine peroxiredoxins. Biochemistry. 2002 Apr 30; 41(17):5493-504.
Score: 0.012