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Connection

Leslie Poole to Humans

This is a "connection" page, showing publications Leslie Poole has written about Humans.
Connection Strength

0.653
  1. Long DL, McCall CE, Poole LB. Glutathionylation of pyruvate dehydrogenase complex E2 and inflammatory cytokine production during acute inflammation are magnified by mitochondrial oxidative stress. Redox Biol. 2023 Sep; 65:102841.
    View in: PubMed
    Score: 0.052
  2. Poole LB, Furdui CM, King SB. Introduction to approaches and tools for the evaluation of protein cysteine oxidation. Essays Biochem. 2020 02 17; 64(1):1-17.
    View in: PubMed
    Score: 0.041
  3. Keyes JD, Parsonage D, Yammani RD, Rogers LC, Kesty C, Furdui CM, Nelson KJ, Poole LB. Endogenous, regulatory cysteine sulfenylation of ERK kinases in response to proliferative signals. Free Radic Biol Med. 2017 11; 112:534-543.
    View in: PubMed
    Score: 0.035
  4. Poole LB, Schöneich C. Introduction: What we do and do not know regarding redox processes of thiols in signaling pathways. Free Radic Biol Med. 2015 Mar; 80:145-7.
    View in: PubMed
    Score: 0.029
  5. Poole LB. The basics of thiols and cysteines in redox biology and chemistry. Free Radic Biol Med. 2015 Mar; 80:148-57.
    View in: PubMed
    Score: 0.029
  6. Furdui CM, Poole LB. Chemical approaches to detect and analyze protein sulfenic acids. Mass Spectrom Rev. 2014 Mar-Apr; 33(2):126-46.
    View in: PubMed
    Score: 0.026
  7. Poole LB, Hall A, Nelson KJ. Overview of peroxiredoxins in oxidant defense and redox regulation. Curr Protoc Toxicol. 2011 Aug; Chapter 7:Unit7.9.
    View in: PubMed
    Score: 0.023
  8. Klomsiri C, Karplus PA, Poole LB. Cysteine-based redox switches in enzymes. Antioxid Redox Signal. 2011 Mar 15; 14(6):1065-77.
    View in: PubMed
    Score: 0.021
  9. Klomsiri C, Nelson KJ, Bechtold E, Soito L, Johnson LC, Lowther WT, Ryu SE, King SB, Furdui CM, Poole LB. Use of dimedone-based chemical probes for sulfenic acid detection evaluation of conditions affecting probe incorporation into redox-sensitive proteins. Methods Enzymol. 2010; 473:77-94.
    View in: PubMed
    Score: 0.020
  10. Nelson KJ, Klomsiri C, Codreanu SG, Soito L, Liebler DC, Rogers LC, Daniel LW, Poole LB. Use of dimedone-based chemical probes for sulfenic acid detection methods to visualize and identify labeled proteins. Methods Enzymol. 2010; 473:95-115.
    View in: PubMed
    Score: 0.020
  11. Hall A, Karplus PA, Poole LB. Typical 2-Cys peroxiredoxins--structures, mechanisms and functions. FEBS J. 2009 May; 276(9):2469-77.
    View in: PubMed
    Score: 0.019
  12. Poole LB. Measurement of protein sulfenic acid content. Curr Protoc Toxicol. 2008 Nov; Chapter 17:Unit17.2.
    View in: PubMed
    Score: 0.019
  13. Poole LB, Nelson KJ. Discovering mechanisms of signaling-mediated cysteine oxidation. Curr Opin Chem Biol. 2008 Feb; 12(1):18-24.
    View in: PubMed
    Score: 0.018
  14. Poole LB. Formation and functions of protein sulfenic acids. Curr Protoc Toxicol. 2004 Feb; Chapter 17:Unit17.1.
    View in: PubMed
    Score: 0.014
  15. Poole LB, Karplus PA, Claiborne A. Protein sulfenic acids in redox signaling. Annu Rev Pharmacol Toxicol. 2004; 44:325-47.
    View in: PubMed
    Score: 0.013
  16. Hu Q, Yammani RD, Brown-Harding H, Soto-Pantoja DR, Poole LB, Lukesh JC. Mitigation of doxorubicin-induced cardiotoxicity with an H2O2-Activated, H2S-Donating hybrid prodrug. Redox Biol. 2022 07; 53:102338.
    View in: PubMed
    Score: 0.012
  17. Das A, Ash D, Fouda AY, Sudhahar V, Kim YM, Hou Y, Hudson FZ, Stansfield BK, Caldwell RB, McMenamin M, Littlejohn R, Su H, Regan MR, Merrill BJ, Poole LB, Kaplan JH, Fukai T, Ushio-Fukai M. Cysteine oxidation of copper transporter CTR1 drives VEGFR2 signalling and angiogenesis. Nat Cell Biol. 2022 01; 24(1):35-50.
    View in: PubMed
    Score: 0.012
  18. Baker LM, Raudonikiene A, Hoffman PS, Poole LB. Essential thioredoxin-dependent peroxiredoxin system from Helicobacter pylori: genetic and kinetic characterization. J Bacteriol. 2001 Mar; 183(6):1961-73.
    View in: PubMed
    Score: 0.011
  19. Randall LM, Dalla Rizza J, Parsonage D, Santos J, Mehl RA, Lowther WT, Poole LB, Denicola A. Unraveling the effects of peroxiredoxin 2 nitration; role of C-terminal tyrosine 193. Free Radic Biol Med. 2019 09; 141:492-501.
    View in: PubMed
    Score: 0.010
  20. Li Z, Forshaw TE, Holmila RJ, Vance SA, Wu H, Poole LB, Furdui CM, King SB. Triphenylphosphonium-Derived Protein Sulfenic Acid Trapping Agents: Synthesis, Reactivity, and Effect on Mitochondrial Function. Chem Res Toxicol. 2019 03 18; 32(3):526-534.
    View in: PubMed
    Score: 0.010
  21. Collins JA, Wood ST, Bolduc JA, Nurmalasari NPD, Chubinskaya S, Poole LB, Furdui CM, Nelson KJ, Loeser RF. Differential peroxiredoxin hyperoxidation regulates MAP kinase signaling in human articular chondrocytes. Free Radic Biol Med. 2019 04; 134:139-152.
    View in: PubMed
    Score: 0.010
  22. Vukelic S, Xu Q, Seidel-Rogol B, Faidley EA, Dikalova AE, Hilenski LL, Jorde U, Poole LB, Lassègue B, Zhang G, Griendling KK. NOX4 (NADPH Oxidase 4) and Poldip2 (Polymerase d-Interacting Protein 2) Induce Filamentous Actin Oxidation and Promote Its Interaction With Vinculin During Integrin-Mediated Cell Adhesion. Arterioscler Thromb Vasc Biol. 2018 10; 38(10):2423-2434.
    View in: PubMed
    Score: 0.009
  23. Nelson KJ, Bolduc JA, Wu H, Collins JA, Burke EA, Reisz JA, Klomsiri C, Wood ST, Yammani RR, Poole LB, Furdui CM, Loeser RF. H2O2 oxidation of cysteine residues in c-Jun N-terminal kinase 2 (JNK2) contributes to redox regulation in human articular chondrocytes. J Biol Chem. 2018 10 19; 293(42):16376-16389.
    View in: PubMed
    Score: 0.009
  24. Bolduc JA, Nelson KJ, Haynes AC, Lee J, Reisz JA, Graff AH, Clodfelter JE, Parsonage D, Poole LB, Furdui CM, Lowther WT. Novel hyperoxidation resistance motifs in 2-Cys peroxiredoxins. J Biol Chem. 2018 07 27; 293(30):11901-11912.
    View in: PubMed
    Score: 0.009
  25. Holmila RJ, Vance SA, Chen X, Wu H, Shukla K, Bharadwaj MS, Mims J, Wary Z, Marrs G, Singh R, Molina AJ, Poole LB, King SB, Furdui CM. Mitochondria-targeted Probes for Imaging Protein Sulfenylation. Sci Rep. 2018 04 27; 8(1):6635.
    View in: PubMed
    Score: 0.009
  26. Portillo-Ledesma S, Randall LM, Parsonage D, Dalla Rizza J, Karplus PA, Poole LB, Denicola A, Ferrer-Sueta G. Differential Kinetics of Two-Cysteine Peroxiredoxin Disulfide Formation Reveal a Novel Model for Peroxide Sensing. Biochemistry. 2018 06 19; 57(24):3416-3424.
    View in: PubMed
    Score: 0.009
  27. Long D, Wu H, Tsang AW, Poole LB, Yoza BK, Wang X, Vachharajani V, Furdui CM, McCall CE. The Oxidative State of Cysteine Thiol 144 Regulates the SIRT6 Glucose Homeostat. Sci Rep. 2017 09 08; 7(1):11005.
    View in: PubMed
    Score: 0.009
  28. Chen X, Wu H, Park CM, Poole TH, Keceli G, Devarie-Baez NO, Tsang AW, Lowther WT, Poole LB, King SB, Xian M, Furdui CM. Discovery of Heteroaromatic Sulfones As a New Class of Biologically Compatible Thiol-Selective Reagents. ACS Chem Biol. 2017 08 18; 12(8):2201-2208.
    View in: PubMed
    Score: 0.009
  29. Mauney CH, Rogers LC, Harris RS, Daniel LW, Devarie-Baez NO, Wu H, Furdui CM, Poole LB, Perrino FW, Hollis T. The SAMHD1 dNTP Triphosphohydrolase Is Controlled by a Redox Switch. Antioxid Redox Signal. 2017 Dec 01; 27(16):1317-1331.
    View in: PubMed
    Score: 0.008
  30. Collins JA, Wood ST, Nelson KJ, Rowe MA, Carlson CS, Chubinskaya S, Poole LB, Furdui CM, Loeser RF. Oxidative Stress Promotes Peroxiredoxin Hyperoxidation and Attenuates Pro-survival Signaling in Aging Chondrocytes. J Biol Chem. 2016 Mar 25; 291(13):6641-54.
    View in: PubMed
    Score: 0.008
  31. Wood ST, Long DL, Reisz JA, Yammani RR, Burke EA, Klomsiri C, Poole LB, Furdui CM, Loeser RF. Cysteine-Mediated Redox Regulation of Cell Signaling in Chondrocytes Stimulated With Fibronectin Fragments. Arthritis Rheumatol. 2016 Jan; 68(1):117-26.
    View in: PubMed
    Score: 0.008
  32. Vera T, D'Agostino RB, Jordan JH, Whitlock MC, Meléndez GC, Lamar ZS, Porosnicu M, Bonkovsky HL, Poole LB, Hundley WG. Relation of Pre-anthracycline Serum Bilirubin Levels to Left Ventricular Ejection Fraction After Chemotherapy. Am J Cardiol. 2015 Dec 01; 116(11):1752-5.
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    Score: 0.008
  33. Langston PK, Yang M, Bierbach U, Parsonage D, Poole LB, Price MJ, Grayson JM. Au-ACRAMTU-PEt3 Alters Redox Balance To Inhibit T Cell Proliferation and Function. J Immunol. 2015 Sep 01; 195(5):1984-94.
    View in: PubMed
    Score: 0.007
  34. Perkins A, Nelson KJ, Parsonage D, Poole LB, Karplus PA. Peroxiredoxins: guardians against oxidative stress and modulators of peroxide signaling. Trends Biochem Sci. 2015 Aug; 40(8):435-45.
    View in: PubMed
    Score: 0.007
  35. Perkins A, Poole LB, Karplus PA. Tuning of peroxiredoxin catalysis for various physiological roles. Biochemistry. 2014 Dec 16; 53(49):7693-705.
    View in: PubMed
    Score: 0.007
  36. Poole TH, Reisz JA, Zhao W, Poole LB, Furdui CM, King SB. Strained cycloalkynes as new protein sulfenic acid traps. J Am Chem Soc. 2014 Apr 30; 136(17):6167-70.
    View in: PubMed
    Score: 0.007
  37. Randall LM, Manta B, Hugo M, Gil M, Batthyàny C, Trujillo M, Poole LB, Denicola A. Nitration transforms a sensitive peroxiredoxin 2 into a more active and robust peroxidase. J Biol Chem. 2014 May 30; 289(22):15536-43.
    View in: PubMed
    Score: 0.007
  38. Klomsiri C, Rogers LC, Soito L, McCauley AK, King SB, Nelson KJ, Poole LB, Daniel LW. Endosomal H2O2 production leads to localized cysteine sulfenic acid formation on proteins during lysophosphatidic acid-mediated cell signaling. Free Radic Biol Med. 2014 Jun; 71:49-60.
    View in: PubMed
    Score: 0.007
  39. Taneja NK, Ganguly T, Bakaletz LO, Nelson KJ, Dubey P, Poole LB, Deora R. D-alanine modification of a protease-susceptible outer membrane component by the Bordetella pertussis dra locus promotes resistance to antimicrobial peptides and polymorphonuclear leukocyte-mediated killing. J Bacteriol. 2013 Nov; 195(22):5102-11.
    View in: PubMed
    Score: 0.007
  40. Lang BS, Gorren AC, Oberdorfer G, Wenzl MV, Furdui CM, Poole LB, Mayer B, Gruber K. Vascular bioactivation of nitroglycerin by aldehyde dehydrogenase-2: reaction intermediates revealed by crystallography and mass spectrometry. J Biol Chem. 2012 Nov 02; 287(45):38124-34.
    View in: PubMed
    Score: 0.006
  41. Salsbury FR, Poole LB, Fetrow JS. Electrostatics of cysteine residues in proteins: parameterization and validation of a simple model. Proteins. 2012 Nov; 80(11):2583-91.
    View in: PubMed
    Score: 0.006
  42. Gretes MC, Poole LB, Karplus PA. Peroxiredoxins in parasites. Antioxid Redox Signal. 2012 Aug 15; 17(4):608-33.
    View in: PubMed
    Score: 0.006
  43. Kaplan N, Urao N, Furuta E, Kim SJ, Razvi M, Nakamura Y, McKinney RD, Poole LB, Fukai T, Ushio-Fukai M. Localized cysteine sulfenic acid formation by vascular endothelial growth factor: role in endothelial cell migration and angiogenesis. Free Radic Res. 2011 Oct; 45(10):1124-35.
    View in: PubMed
    Score: 0.006
  44. Wani R, Qian J, Yin L, Bechtold E, King SB, Poole LB, Paek E, Tsang AW, Furdui CM. Isoform-specific regulation of Akt by PDGF-induced reactive oxygen species. Proc Natl Acad Sci U S A. 2011 Jun 28; 108(26):10550-5.
    View in: PubMed
    Score: 0.006
  45. Saunders JA, Rogers LC, Klomsiri C, Poole LB, Daniel LW. Reactive oxygen species mediate lysophosphatidic acid induced signaling in ovarian cancer cells. Free Radic Biol Med. 2010 Dec 15; 49(12):2058-67.
    View in: PubMed
    Score: 0.005
  46. Hall A, Parsonage D, Poole LB, Karplus PA. Structural evidence that peroxiredoxin catalytic power is based on transition-state stabilization. J Mol Biol. 2010 Sep 10; 402(1):194-209.
    View in: PubMed
    Score: 0.005
  47. Smith-Pearson PS, Kooshki M, Spitz DR, Poole LB, Zhao W, Robbins ME. Decreasing peroxiredoxin II expression decreases glutathione, alters cell cycle distribution, and sensitizes glioma cells to ionizing radiation and H(2)O(2). Free Radic Biol Med. 2008 Oct 15; 45(8):1178-89.
    View in: PubMed
    Score: 0.005
  48. Hutson SM, Poole LB, Coles S, Conway ME. Redox regulation and trapping sulfenic acid in the peroxide-sensitive human mitochondrial branched chain aminotransferase. Methods Mol Biol. 2008; 476:139-52.
    View in: PubMed
    Score: 0.004
  49. Jönsson TJ, Murray MS, Johnson LC, Poole LB, Lowther WT. Structural basis for the retroreduction of inactivated peroxiredoxins by human sulfiredoxin. Biochemistry. 2005 Jun 21; 44(24):8634-42.
    View in: PubMed
    Score: 0.004
  50. Conway ME, Poole LB, Hutson SM. Roles for cysteine residues in the regulatory CXXC motif of human mitochondrial branched chain aminotransferase enzyme. Biochemistry. 2004 Jun 15; 43(23):7356-64.
    View in: PubMed
    Score: 0.003
  51. Wood ZA, Poole LB, Karplus PA. Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling. Science. 2003 Apr 25; 300(5619):650-3.
    View in: PubMed
    Score: 0.003
  52. Conway ME, Yennawar N, Wallin R, Poole LB, Hutson SM. Human mitochondrial branched chain aminotransferase: structural basis for substrate specificity and role of redox active cysteines. Biochim Biophys Acta. 2003 Apr 11; 1647(1-2):61-5.
    View in: PubMed
    Score: 0.003
  53. Conway ME, Yennawar N, Wallin R, Poole LB, Hutson SM. Identification of a peroxide-sensitive redox switch at the CXXC motif in the human mitochondrial branched chain aminotransferase. Biochemistry. 2002 Jul 23; 41(29):9070-8.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.