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Connection

Carl Langefeld to Insulin Resistance

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This is a "connection" page, showing publications Carl Langefeld has written about Insulin Resistance.
Carl Langefeld
Connection Strength
2.783
Insulin Resistance
  1. Langefeld CD, Wagenknecht LE, Rotter JI, Williams AH, Hokanson JE, Saad MF, Bowden DW, Haffner S, Norris JM, Rich SS, Mitchell BD. Linkage of the metabolic syndrome to 1q23-q31 in Hispanic families: the Insulin Resistance Atherosclerosis Study Family Study. Diabetes. 2004 Apr; 53(4):1170-4.
    View in: PubMed
    Score: 0.186
  2. Bensen JT, Hsu FC, Brown WM, Sutton BS, Norris JM, Tracy RP, Jenny NS, Saad MF, Haffner S, Bowden DW, Langefeld CD. Association analysis of the plasminogen activator inhibitor-1 4G/5G polymorphism in Hispanics and African Americans: the IRAS family study. Hum Hered. 2004; 57(3):128-37.
    View in: PubMed
    Score: 0.183
  3. Sharma NK, Chuang Key CC, Civelek M, Wabitsch M, Comeau ME, Langefeld CD, Parks JS, Das SK. Genetic Regulation of Enoyl-CoA Hydratase Domain-Containing 3 in Adipose Tissue Determines Insulin Sensitivity in African Americans and Europeans. Diabetes. 2019 07; 68(7):1508-1522.
    View in: PubMed
    Score: 0.132
  4. Young KA, Maturu A, Lorenzo C, Langefeld CD, Wagenknecht LE, Chen YI, Taylor KD, Rotter JI, Norris JM, Rasouli N. The triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio as a predictor of insulin resistance, ß-cell function, and diabetes in Hispanics and African Americans. J Diabetes Complications. 2019 02; 33(2):118-122.
    View in: PubMed
    Score: 0.128
  5. McClain DA, Sharma NK, Jain S, Harrison A, Salaye LN, Comeau ME, Langefeld CD, Lorenzo FR, Das SK. Adipose Tissue Transferrin and Insulin Resistance. J Clin Endocrinol Metab. 2018 11 01; 103(11):4197-4208.
    View in: PubMed
    Score: 0.128
  6. Palmer ND, Okut H, Hsu FC, Ng MCY, Chen YI, Goodarzi MO, Taylor KD, Norris JM, Lorenzo C, Rotter JI, Bergman RN, Langefeld CD, Wagenknecht LE, Bowden DW. Metabolomics Identifies Distinctive Metabolite Signatures for Measures of Glucose Homeostasis: The Insulin Resistance Atherosclerosis Family Study (IRAS-FS). J Clin Endocrinol Metab. 2018 05 01; 103(5):1877-1888.
    View in: PubMed
    Score: 0.124
  7. Gao C, Hsu FC, Dimitrov LM, Okut H, Chen YI, Taylor KD, Rotter JI, Langefeld CD, Bowden DW, Palmer ND. A genome-wide linkage and association analysis of imputed insertions and deletions with cardiometabolic phenotypes in Mexican Americans: The Insulin Resistance Atherosclerosis Family Study. Genet Epidemiol. 2017 05; 41(4):353-362.
    View in: PubMed
    Score: 0.115
  8. Tabb KL, Hellwege JN, Palmer ND, Dimitrov L, Sajuthi S, Taylor KD, Ng MC, Hawkins GA, Chen YI, Brown WM, McWilliams D, Williams A, Lorenzo C, Norris JM, Long J, Rotter JI, Curran JE, Blangero J, Wagenknecht LE, Langefeld CD, Bowden DW. Analysis of Whole Exome Sequencing with Cardiometabolic Traits Using Family-Based Linkage and Association in the IRAS Family Study. Ann Hum Genet. 2017 Mar; 81(2):49-58.
    View in: PubMed
    Score: 0.113
  9. Hellwege JN, Palmer ND, Dimitrov L, Keaton JM, Tabb KL, Sajuthi S, Taylor KD, Ng MC, Speliotes EK, Hawkins GA, Long J, Ida Chen YD, Lorenzo C, Norris JM, Rotter JI, Langefeld CD, Wagenknecht LE, Bowden DW. Genome-wide linkage and association analysis of cardiometabolic phenotypes in Hispanic Americans. J Hum Genet. 2017 Feb; 62(2):175-184.
    View in: PubMed
    Score: 0.110
  10. Palmer ND, Wagenknecht LE, Langefeld CD, Wang N, Buchanan TA, Xiang AH, Allayee H, Bergman RN, Raffel LJ, Chen YD, Haritunians T, Fingerlin T, Goodarzi MO, Taylor KD, Rotter JI, Watanabe RM, Bowden DW. Improved Performance of Dynamic Measures of Insulin Response Over Surrogate Indices to Identify Genetic Contributors of Type 2 Diabetes: The GUARDIAN Consortium. Diabetes. 2016 07; 65(7):2072-80.
    View in: PubMed
    Score: 0.108
  11. Sharma NK, Sajuthi SP, Chou JW, Calles-Escandon J, Demons J, Rogers S, Ma L, Palmer ND, McWilliams DR, Beal J, Comeau ME, Cherry K, Hawkins GA, Menon L, Kouba E, Davis D, Burris M, Byerly SJ, Easter L, Bowden DW, Freedman BI, Langefeld CD, Das SK. Tissue-Specific and Genetic Regulation of Insulin Sensitivity-Associated Transcripts in African Americans. J Clin Endocrinol Metab. 2016 Apr; 101(4):1455-68.
    View in: PubMed
    Score: 0.105
  12. Hellwege JN, Palmer ND, Raffield LM, Ng MC, Hawkins GA, Long J, Lorenzo C, Norris JM, Ida Chen YD, Speliotes EK, Rotter JI, Langefeld CD, Wagenknecht LE, Bowden DW. Genome-wide family-based linkage analysis of exome chip variants and cardiometabolic risk. Genet Epidemiol. 2014 May; 38(4):345-52.
    View in: PubMed
    Score: 0.093
  13. Goodarzi MO, Langefeld CD, Xiang AH, Chen YD, Guo X, Hanley AJ, Raffel LJ, Kandeel F, Nadler JL, Buchanan TA, Norris JM, Fingerlin TE, Lorenzo C, Rewers MJ, Haffner SM, Bowden DW, Rich SS, Bergman RN, Rotter JI, Watanabe RM, Wagenknecht LE. Insulin sensitivity and insulin clearance are heritable and have strong genetic correlation in Mexican Americans. Obesity (Silver Spring). 2014 Apr; 22(4):1157-64.
    View in: PubMed
    Score: 0.093
  14. Miller MR, Pereira RI, Langefeld CD, Lorenzo C, Rotter JI, Chen YD, Bergman RN, Wagenknecht LE, Norris JM, Fingerlin TE. Levels of free fatty acids (FFA) are associated with insulin resistance but do not explain the relationship between adiposity and insulin resistance in Hispanic Americans: the IRAS Family Study. J Clin Endocrinol Metab. 2012 Sep; 97(9):3285-91.
    View in: PubMed
    Score: 0.082
  15. Wagenknecht LE, Palmer ND, Bowden DW, Rotter JI, Norris JM, Ziegler J, Chen YD, Haffner S, Scherzinger A, Langefeld CD. Association of PNPLA3 with non-alcoholic fatty liver disease in a minority cohort: the Insulin Resistance Atherosclerosis Family Study. Liver Int. 2011 Mar; 31(3):412-6.
    View in: PubMed
    Score: 0.075
  16. Bowden DW, An SS, Palmer ND, Brown WM, Norris JM, Haffner SM, Hawkins GA, Guo X, Rotter JI, Chen YD, Wagenknecht LE, Langefeld CD. Molecular basis of a linkage peak: exome sequencing and family-based analysis identify a rare genetic variant in the ADIPOQ gene in the IRAS Family Study. Hum Mol Genet. 2010 Oct 15; 19(20):4112-20.
    View in: PubMed
    Score: 0.072
  17. Miller MR, Zhang W, Sibbel SP, Langefeld CD, Bowden DW, Haffner SM, Bergman RN, Norris JM, Fingerlin TE. Variant in the 3' region of the IkappaBalpha gene associated with insulin resistance in Hispanic Americans: The IRAS Family Study. Obesity (Silver Spring). 2010 Mar; 18(3):555-62.
    View in: PubMed
    Score: 0.068
  18. Sutton BS, Palmer ND, Langefeld CD, Xue B, Proctor A, Ziegler JT, Haffner SM, Norris JM, Bowden DW. Association of SSTR2 polymorphisms and glucose homeostasis phenotypes: the Insulin Resistance Atherosclerosis Family Study. Diabetes. 2009 Jun; 58(6):1457-62.
    View in: PubMed
    Score: 0.066
  19. Palmer ND, Langefeld CD, Bryer-Ash M, Rotter JI, Taylor KD, Bowden DW. Association of the Kir6.2 E23K variant with reduced acute insulin response in African-Americans. J Clin Endocrinol Metab. 2008 Dec; 93(12):4979-83.
    View in: PubMed
    Score: 0.063
  20. Palmer ND, Goodarzi MO, Langefeld CD, Ziegler J, Norris JM, Haffner SM, Bryer-Ash M, Bergman RN, Wagenknecht LE, Taylor KD, Rotter JI, Bowden DW. Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study. Diabetes. 2008 Apr; 57(4):1093-100.
    View in: PubMed
    Score: 0.061
  21. Palmer ND, Lehtinen AB, Langefeld CD, Campbell JK, Haffner SM, Norris JM, Bergman RN, Goodarzi MO, Rotter JI, Bowden DW. Association of TCF7L2 gene polymorphisms with reduced acute insulin response in Hispanic Americans. J Clin Endocrinol Metab. 2008 Jan; 93(1):304-9.
    View in: PubMed
    Score: 0.060
  22. Gallagher CJ, Langefeld CD, Gordon CJ, Campbell JK, Mychaleckyj JC, Mychalecky JC, Bryer-Ash M, Rich SS, Bowden DW, Sale MM. Association of the estrogen receptor-alpha gene with the metabolic syndrome and its component traits in African-American families: the Insulin Resistance Atherosclerosis Family Study. Diabetes. 2007 Aug; 56(8):2135-41.
    View in: PubMed
    Score: 0.058
  23. Hanley AJ, Bowden D, Wagenknecht LE, Balasubramanyam A, Langfeld C, Saad MF, Rotter JI, Guo X, Chen YD, Bryer-Ash M, Norris JM, Haffner SM. Associations of adiponectin with body fat distribution and insulin sensitivity in nondiabetic Hispanics and African-Americans. J Clin Endocrinol Metab. 2007 Jul; 92(7):2665-71.
    View in: PubMed
    Score: 0.057
  24. Palmer ND, Langefeld CD, Campbell JK, Williams AH, Saad M, Norris JM, Haffner SM, Rotter JI, Wagenknecht LE, Bergman RN, Rich SS, Bowden DW. Genetic mapping of disposition index and acute insulin response loci on chromosome 11q. The Insulin Resistance Atherosclerosis Study (IRAS) Family Study. Diabetes. 2006 Apr; 55(4):911-8.
    View in: PubMed
    Score: 0.053
  25. Sutton BS, Weinert S, Langefeld CD, Williams AH, Campbell JK, Saad MF, Haffner SM, Norris JM, Bowden DW. Genetic analysis of adiponectin and obesity in Hispanic families: the IRAS Family Study. Hum Genet. 2005 Jul; 117(2-3):107-18.
    View in: PubMed
    Score: 0.050
  26. Palmer ND, Bento JL, Mychaleckyj JC, Langefeld CD, Campbell JK, Norris JM, Haffner SM, Bergman RN, Bowden DW. Association of protein tyrosine phosphatase 1B gene polymorphisms with measures of glucose homeostasis in Hispanic Americans: the insulin resistance atherosclerosis study (IRAS) family study. Diabetes. 2004 Nov; 53(11):3013-9.
    View in: PubMed
    Score: 0.048
  27. Rich SS, Bowden DW, Haffner SM, Norris JM, Saad MF, Mitchell BD, Rotter JI, Langefeld CD, Wagenknecht LE, Bergman RN. Identification of quantitative trait loci for glucose homeostasis: the Insulin Resistance Atherosclerosis Study (IRAS) Family Study. Diabetes. 2004 Jul; 53(7):1866-75.
    View in: PubMed
    Score: 0.047
  28. Wagenknecht LE, Langefeld CD, Scherzinger AL, Norris JM, Haffner SM, Saad MF, Bergman RN. Insulin sensitivity, insulin secretion, and abdominal fat: the Insulin Resistance Atherosclerosis Study (IRAS) Family Study. Diabetes. 2003 Oct; 52(10):2490-6.
    View in: PubMed
    Score: 0.045
  29. Henkin L, Bergman RN, Bowden DW, Ellsworth DL, Haffner SM, Langefeld CD, Mitchell BD, Norris JM, Rewers M, Saad MF, Stamm E, Wagenknecht LE, Rich SS. Genetic epidemiology of insulin resistance and visceral adiposity. The IRAS Family Study design and methods. Ann Epidemiol. 2003 Apr; 13(4):211-7.
    View in: PubMed
    Score: 0.043
  30. Sharma NK, Comeau ME, Montoya D, Pellegrini M, Howard TD, Langefeld CD, Das SK. Integrative Analysis of Glucometabolic Traits, Adipose Tissue DNA Methylation, and Gene Expression Identifies Epigenetic Regulatory Mechanisms of Insulin Resistance and Obesity in African Americans. Diabetes. 2020 12; 69(12):2779-2793.
    View in: PubMed
    Score: 0.036
  31. Gao C, Tabb KL, Dimitrov LM, Taylor KD, Wang N, Guo X, Long J, Rotter JI, Watanabe RM, Curran JE, Blangero J, Langefeld CD, Bowden DW, Palmer ND. Exome Sequencing Identifies Genetic Variants Associated with Circulating Lipid Levels in Mexican Americans: The Insulin Resistance Atherosclerosis Family Study (IRASFS). Sci Rep. 2018 04 04; 8(1):5603.
    View in: PubMed
    Score: 0.031
  32. Liu CT, Raghavan S, Maruthur N, Kabagambe EK, Hong J, Ng MC, Hivert MF, Lu Y, An P, Bentley AR, Drolet AM, Gaulton KJ, Guo X, Armstrong LL, Irvin MR, Li M, Lipovich L, Rybin DV, Taylor KD, Agyemang C, Palmer ND, Cade BE, Chen WM, Dauriz M, Delaney JA, Edwards TL, Evans DS, Evans MK, Lange LA, Leong A, Liu J, Liu Y, Nayak U, Patel SR, Porneala BC, Rasmussen-Torvik LJ, Snijder MB, Stallings SC, Tanaka T, Yanek LR, Zhao W, Becker DM, Bielak LF, Biggs ML, Bottinger EP, Bowden DW, Chen G, Correa A, Couper DJ, Crawford DC, Cushman M, Eicher JD, Fornage M, Franceschini N, Fu YP, Goodarzi MO, Gottesman O, Hara K, Harris TB, Jensen RA, Johnson AD, Jhun MA, Karter AJ, Keller MF, Kho AN, Kizer JR, Krauss RM, Langefeld CD, Li X, Liang J, Liu S, Lowe WL, Mosley TH, North KE, Pacheco JA, Peyser PA, Patrick AL, Rice KM, Selvin E, Sims M, Smith JA, Tajuddin SM, Vaidya D, Wren MP, Yao J, Zhu X, Ziegler JT, Zmuda JM, Zonderman AB, Zwinderman AH, Adeyemo A, Boerwinkle E, Ferrucci L, Hayes MG, Kardia SL, Miljkovic I, Pankow JS, Rotimi CN, Sale MM, Wagenknecht LE, Arnett DK, Chen YD, Nalls MA, Province MA, Kao WH, Siscovick DS, Psaty BM, Wilson JG, Loos RJ, Dupuis J, Rich SS, Florez JC, Rotter JI, Morris AP, Meigs JB. Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin. Am J Hum Genet. 2016 Jul 07; 99(1):56-75.
    View in: PubMed
    Score: 0.027
  33. Hellwege JN, Palmer ND, Ziegler JT, Langefeld CD, Lorenzo C, Norris JM, Takamura T, Bowden DW. Genetic variants in selenoprotein P plasma 1 gene (SEPP1) are associated with fasting insulin and first phase insulin response in Hispanics. Gene. 2014 Jan 15; 534(1):33-9.
    View in: PubMed
    Score: 0.023
  34. Sandy An S, Palmer ND, Hanley AJ, Ziegler JT, Mark Brown W, Freedman BI, Register TC, Rotter JI, Guo X, Ida Chen YD, Wagenknecht LE, Langefeld CD, Bowden DW. Genetic analysis of adiponectin variation and its association with type 2 diabetes in African Americans. Obesity (Silver Spring). 2013 Dec; 21(12):E721-9.
    View in: PubMed
    Score: 0.022
  35. An SS, Palmer ND, Hanley AJ, Ziegler JT, Brown WM, Haffner SM, Norris JM, Rotter JI, Guo X, Chen YD, Wagenknecht LE, Langefeld CD, Bowden DW. Estimating the contributions of rare and common genetic variations and clinical measures to a model trait: adiponectin. Genet Epidemiol. 2013 Jan; 37(1):13-24.
    View in: PubMed
    Score: 0.021
  36. Schmitz KJ, Skinner HG, Bautista LE, Fingerlin TE, Langefeld CD, Hicks PJ, Haffner SM, Bryer-Ash M, Wagenknecht LE, Bowden DW, Norris JM, Engelman CD. Association of 25-hydroxyvitamin D with blood pressure in predominantly 25-hydroxyvitamin D deficient Hispanic and African Americans. Am J Hypertens. 2009 Aug; 22(8):867-70.
    View in: PubMed
    Score: 0.017
  37. Burdon KP, Bento JL, Langefeld CD, Campbell JK, Carr JJ, Wagenknecht LM, Herrington DM, Freedman BI, Rich SS, Bowden DW. Association of protein tyrosine phosphatase-N1 polymorphisms with coronary calcified plaque in the Diabetes Heart Study. Diabetes. 2006 Mar; 55(3):651-8.
    View in: PubMed
    Score: 0.013
  38. Hsu FC, Zaccaro DJ, Lange LA, Arnett DK, Langefeld CD, Wagenknecht LE, Herrington DM, Beck SR, Freedman BI, Bowden DW, Rich SS. The impact of pedigree structure on heritability estimates for pulse pressure in three studies. Hum Hered. 2005; 60(2):63-72.
    View in: PubMed
    Score: 0.013
  39. Rich SS, Bowden DW, Haffner SM, Norris JM, Saad MF, Mitchell BD, Rotter JI, Langefeld CD, Hedrick CC, Wagenknecht LE, Bergman RN. A genome scan for fasting insulin and fasting glucose identifies a quantitative trait locus on chromosome 17p: the insulin resistance atherosclerosis study (IRAS) family study. Diabetes. 2005 Jan; 54(1):290-5.
    View in: PubMed
    Score: 0.012
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