Herbert Bonkovsky to Liver
This is a "connection" page, showing publications Herbert Bonkovsky has written about Liver.
Connection Strength
8.627
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Bonkovsky HL, Hou W, Steuerwald N, Tian Q, Li T, Parsons J, Hamilton A, Hwang S, Schrum L. Heme status affects human hepatic messenger RNA and microRNA expression. World J Gastroenterol. 2013 Mar 14; 19(10):1593-601.
Score: 0.346
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Ghosh S, Kaplan KJ, Schrum LW, Bonkovsky HL. Cytoskeletal proteins: shaping progression of hepatitis C virus-induced liver disease. Int Rev Cell Mol Biol. 2013; 302:279-319.
Score: 0.341
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Bonkovsky HL. Risk factors for porphyria cutanea tarda -the iron/HFE connection. Liver Int. 2013 Jan; 33(1):162.
Score: 0.337
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Ryan Caballes F, Sendi H, Bonkovsky HL. Hepatitis C, porphyria cutanea tarda and liver iron: an update. Liver Int. 2012 Jul; 32(6):880-93.
Score: 0.325
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Tian Q, Li T, Hou W, Zheng J, Schrum LW, Bonkovsky HL. Lon peptidase 1 (LONP1)-dependent breakdown of mitochondrial 5-aminolevulinic acid synthase protein by heme in human liver cells. J Biol Chem. 2011 Jul 29; 286(30):26424-30.
Score: 0.306
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Panov AV, Vavilin VA, Lyakhovich VV, Brooks BR, Bonkovsky HL. Effect of bovine serum albumin on mitochondrial respiration in the brain and liver of mice and rats. Bull Exp Biol Med. 2010 Aug; 149(2):187-90.
Score: 0.288
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Russo MW, Scobey M, Bonkovsky HL. Drug-induced liver injury associated with statins. Semin Liver Dis. 2009 Nov; 29(4):412-22.
Score: 0.273
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Zheng J, Tian Q, Hou W, Watts JA, Schrum LW, Bonkovsky HL. Tissue-specific expression of ALA synthase-1 and heme oxygenase-1 and their expression in livers of rats chronically exposed to ethanol. FEBS Lett. 2008 Jun 11; 582(13):1829-34.
Score: 0.247
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Siddiqui J, Jaffe PE, Aziz K, Forouhar F, Sheppard R, Covault J, Bonkovsky HL. Fatal air and bile embolism after percutaneous liver biopsy and ERCP. Gastrointest Endosc. 2005 Jan; 61(1):153-7.
Score: 0.196
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Gildemeister OS, Pepe JA, Lambrecht RW, Bonkovsky HL. Induction of heme oxygenase-1 by phenylarsine oxide. Studies in cultured primary liver cells. Mol Cell Biochem. 2001 Oct; 226(1-2):17-26.
Score: 0.156
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Bonkovsky HL, Davidoff A, Stark DD. Hepatic iron concentration and total body iron stores in thalassemia major. N Engl J Med. 2000 Nov 30; 343(22):1656; author reply 1657.
Score: 0.148
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Lu TH, Shan Y, Pepe J, Lambrecht RW, Bonkovsky HL. Upstream regulatory elements in chick heme oxygenase-1 promoter: a study in primary cultures of chick embryo liver cells. Mol Cell Biochem. 2000 Jun; 209(1-2):17-27.
Score: 0.143
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Kohlroser J, Mathai J, Reichheld J, Banner BF, Bonkovsky HL. Hepatotoxicity due to troglitazone: report of two cases and review of adverse events reported to the United States Food and Drug Administration. Am J Gastroenterol. 2000 Jan; 95(1):272-6.
Score: 0.139
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Shan Y, Lambrecht RW, Hong Lu T, Bonkovsky HL. Effects of phenylarsine oxide on expression of heme oxygenase-1 reporter constructs in transiently transfected cultures of chick embryo liver cells. Arch Biochem Biophys. 1999 Dec 15; 372(2):224-9.
Score: 0.138
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Lambrecht RW, Gildemeister OS, Pepe JA, Tortorelli KD, Williams A, Bonkovsky HL. Effects of antidepressants and benzodiazepine-type anxiolytic agents on hepatic porphyrin accumulation in primary cultures of chick embryo liver cells. J Pharmacol Exp Ther. 1999 Dec; 291(3):1150-5.
Score: 0.138
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Kolluri S, Elbirt KK, Bonkovsky HL. Heme biosynthesis in a chicken hepatoma cell line (LMH): comparison with primary chick embryo liver cells (CELC). Biochim Biophys Acta. 1999 Nov 16; 1472(3):658-67.
Score: 0.137
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Salaye L, Bychkova I, Sink S, Kovalic AJ, Bharadwaj MS, Lorenzo F, Jain S, Harrison AV, Davis AT, Turnbull K, Meegalla NT, Lee SH, Cooksey R, Donati GL, Kavanagh K, Bonkovsky HL, McClain DA. A Low Iron Diet Protects from Steatohepatitis in a Mouse Model. Nutrients. 2019 Sep 10; 11(9).
Score: 0.136
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Bonkovsky HL, Rubin RB, Cable EE, Davidoff A, Rijcken TH, Stark DD. Hepatic iron concentration: noninvasive estimation by means of MR imaging techniques. Radiology. 1999 Jul; 212(1):227-34.
Score: 0.134
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Fernandez M, Bonkovsky HL. Increased heme oxygenase-1 gene expression in liver cells and splanchnic organs from portal hypertensive rats. Hepatology. 1999 Jun; 29(6):1672-9.
Score: 0.133
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Sendi H, Mead I, Wan M, Mehrab-Mohseni M, Koch K, Atala A, Bonkovsky HL, Bishop CE. miR-122 inhibition in a human liver organoid model leads to liver inflammation, necrosis, steatofibrosis and dysregulated insulin signaling. PLoS One. 2018; 13(7):e0200847.
Score: 0.125
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Hahn M, Gildemeister OS, Krauss GL, Pepe JA, Lambrecht RW, Donohue S, Bonkovsky HL. Effects of new anticonvulsant medications on porphyrin synthesis in cultured liver cells: potential implications for patients with acute porphyria. Neurology. 1997 Jul; 49(1):97-106.
Score: 0.116
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Cable EE, Gildemeister OS, Pepe JA, Lambrecht RW, Bonkovsky HL. Mechanism of induction of heme oxygenase by metalloporphyrins in primary chick embryo liver cells: evidence against a stress-mediated response. Mol Cell Biochem. 1997 Apr; 169(1-2):13-20.
Score: 0.114
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Bonkovsky HL, Gildemeister OS, Pepe JA, Lambrecht RW, Hrkal Z. Haemopexin and uptake of haem by liver cells. Eur J Clin Chem Clin Biochem. 1996 Nov; 34(11):931-2.
Score: 0.111
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Cable EE, Gildemeister OS, Pepe JA, Donohue SE, Lambrecht RW, Bonkovsky HL. Hepatic 5-aminolevulinic acid synthase mRNA stability is modulated by inhibitors of heme biosynthesis and by metalloporphyrins. Eur J Biochem. 1996 Aug 15; 240(1):112-7.
Score: 0.110
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Lu TH, Pepe J, Lambrecht RW, Bonkovsky HL. Regulation of metallothionein gene expression. Studies in transfected primary cultures of chick embryo liver cells. Biochimie. 1996; 78(4):236-44.
Score: 0.105
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Wang G, Bonkovsky HL, de Lemos A, Burczynski FJ. Recent insights into the biological functions of liver fatty acid binding protein 1. J Lipid Res. 2015 Dec; 56(12):2238-47.
Score: 0.103
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Barton AL, Banner BF, Cable EE, Bonkovsky HL. Distribution of iron in the liver predicts the response of chronic hepatitis C infection to interferon therapy. Am J Clin Pathol. 1995 Apr; 103(4):419-24.
Score: 0.100
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Cable EE, Pepe JA, Donohue SE, Lambrecht RW, Bonkovsky HL. Effects of mifepristone (RU-486) on heme metabolism and cytochromes P-450 in cultured chick embryo liver cells, possible implications for acute porphyria. Eur J Biochem. 1994 Oct 15; 225(2):651-7.
Score: 0.097
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Cable EE, Pepe JA, Karamitsios NC, Lambrecht RW, Bonkovsky HL. Differential effects of metalloporphyrins on messenger RNA levels of delta-aminolevulinate synthase and heme oxygenase. Studies in cultured chick embryo liver cells. J Clin Invest. 1994 Aug; 94(2):649-54.
Score: 0.095
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Russo SM, Pepe JA, Cable EE, Lambrecht RW, Bonkovsky HL. Repression of ALA synthase by heme and zinc-mesoporphyrin in a chick embryo liver cell culture model of acute porphyria. Eur J Clin Invest. 1994 Jun; 24(6):406-15.
Score: 0.094
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deLemos AS, Foureau DM, Jacobs C, Ahrens W, Russo MW, Bonkovsky HL. Drug-induced liver injury with autoimmune features. Semin Liver Dis. 2014 May; 34(2):194-204.
Score: 0.094
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Bonkovsky HL, Kane RE, Jones DP, Galinsky RE, Banner B. Acute hepatic and renal toxicity from low doses of acetaminophen in the absence of alcohol abuse or malnutrition: evidence for increased susceptibility to drug toxicity due to cardiopulmonary and renal insufficiency. Hepatology. 1994 May; 19(5):1141-8.
Score: 0.093
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Lambrecht RW, Cable JW, Pepe JA, Bonkovsky HL. 3,5,5-Trimethylhexanoylferrocene induction of heme oxygenase activity in normal hepatocytes. Biochem Pharmacol. 1994 Apr 29; 47(9):1669-76.
Score: 0.093
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Kleiner DE, Chalasani NP, Lee WM, Fontana RJ, Bonkovsky HL, Watkins PB, Hayashi PH, Davern TJ, Navarro V, Reddy R, Talwalkar JA, Stolz A, Gu J, Barnhart H, Hoofnagle JH. Hepatic histological findings in suspected drug-induced liver injury: systematic evaluation and clinical associations. Hepatology. 2014 Feb; 59(2):661-70.
Score: 0.091
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Cable EE, Cable JW, Bonkovsky HL. Repression of hepatic delta-aminolevulinate synthase by heme and metalloporphyrins: relationship to inhibition of heme oxygenase. Hepatology. 1993 Jul; 18(1):119-27.
Score: 0.088
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Russo MW, Narang T, Eskind L, Hayes D, Casingal V, Purdum PP, Hanson JS, Ahrens W, Norton J, Bonkovsky H. Intravenous interferon administered during liver transplantation is not effective in preventing hepatitis C reinfection. Dig Dis Sci. 2013 Oct; 58(10):3010-6.
Score: 0.088
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Srivastava KK, Cable EE, Donohue SE, Bonkovsky HL. Molecular basis for heme-dependent induction of heme oxygenase in primary cultures of chick embryo hepatocytes. Demonstration of acquired refractoriness to heme. Eur J Biochem. 1993 May 01; 213(3):909-17.
Score: 0.087
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Urban TJ, Shen Y, Stolz A, Chalasani N, Fontana RJ, Rochon J, Ge D, Shianna KV, Daly AK, Lucena MI, Nelson MR, Molokhia M, Aithal GP, Floratos A, Pe'er I, Serrano J, Bonkovsky H, Davern TJ, Lee WM, Navarro VJ, Talwalkar JA, Goldstein DB, Watkins PB. Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs. Pharmacogenet Genomics. 2012 Nov; 22(11):784-95.
Score: 0.084
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Bonkovsky HL, Cable EE, Cable JW, Donohue SE, White EC, Greene YJ, Lambrecht RW, Srivastava KK, Arnold WN. Porphyrogenic properties of the terpenes camphor, pinene, and thujone (with a note on historic implications for absinthe and the illness of Vincent van Gogh). Biochem Pharmacol. 1992 Jun 09; 43(11):2359-68.
Score: 0.082
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Bell LN, Vuppalanchi R, Watkins PB, Bonkovsky HL, Serrano J, Fontana RJ, Wang M, Rochon J, Chalasani N. Serum proteomic profiling in patients with drug-induced liver injury. Aliment Pharmacol Ther. 2012 Mar; 35(5):600-12.
Score: 0.080
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Bonkovsky HL, Fiellin DA, Smith GS, Slaker DP, Simon D, Galambos JT. A randomized, controlled trial of treatment of alcoholic hepatitis with parenteral nutrition and oxandrolone. I. Short-term effects on liver function. Am J Gastroenterol. 1991 Sep; 86(9):1200-8.
Score: 0.078
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Bonkovsky HL, Healey JF, Lourie AN, Gerron GG. Intravenous heme-albumin in acute intermittent porphyria: evidence for repletion of hepatic hemoproteins and regulatory heme pools. Am J Gastroenterol. 1991 Aug; 86(8):1050-6.
Score: 0.077
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Rakoski MO, Brown MB, Fontana RJ, Bonkovsky HL, Brunt EM, Goodman ZD, Lok AS, Omary MB. Mallory-Denk bodies are associated with outcomes and histologic features in patients with chronic hepatitis C. Clin Gastroenterol Hepatol. 2011 Oct; 9(10):902-909.e1.
Score: 0.077
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Evans CO, Healey JF, Greene Y, Bonkovsky HL. Cloning, sequencing and expression of cDNA for chick liver haem oxygenase. Comparison of avian and mammalian cDNAs and deduced proteins. Biochem J. 1991 Feb 01; 273 ( Pt 3):659-66.
Score: 0.075
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Bonkovsky HL. Iron and the liver. Am J Med Sci. 1991 Jan; 301(1):32-43.
Score: 0.074
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Bonkovsky HL, Slaker DP, Bills EB, Wolf DC. Usefulness and limitations of laboratory and hepatic imaging studies in iron-storage disease. Gastroenterology. 1990 Oct; 99(4):1079-91.
Score: 0.073
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Vuppalanchi R, Hayashi PH, Chalasani N, Fontana RJ, Bonkovsky H, Saxena R, Kleiner D, Hoofnagle JH. Duloxetine hepatotoxicity: a case-series from the drug-induced liver injury network. Aliment Pharmacol Ther. 2010 Nov; 32(9):1174-83.
Score: 0.073
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Ghany MG, Lok AS, Everhart JE, Everson GT, Lee WM, Curto TM, Wright EC, Stoddard AM, Sterling RK, Di Bisceglie AM, Bonkovsky HL, Morishima C, Morgan TR, Dienstag JL. Predicting clinical and histologic outcomes based on standard laboratory tests in advanced chronic hepatitis C. Gastroenterology. 2010 Jan; 138(1):136-46.
Score: 0.068
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Bonkovsky HL. Mechanism of iron potentiation of hepatic uroporphyria: studies in cultured chick embryo liver cells. Hepatology. 1989 Sep; 10(3):354-64.
Score: 0.068
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Lincoln BC, Aw TY, Bonkovsky HL. Heme catabolism in cultured hepatocytes: evidence that heme oxygenase is the predominant pathway and that a proportion of synthesized heme is converted rapidly to biliverdin. Biochim Biophys Acta. 1989 Jul 21; 992(1):49-58.
Score: 0.067
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Sinclair P, Frezza J, Sinclair J, Bement W, Haugen S, Healey J, Bonkovsky H. Immunochemical detection of different isoenzymes of cytochrome P-450 induced in chick hepatocyte cultures. Biochem J. 1989 Feb 15; 258(1):237-45.
Score: 0.065
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Lincoln BC, Alvarado A, Setty N, Bonkovsky HL. Tryptophan 2,3-dioxygenase in chick embryo hepatocytes: studies in ovo and in culture. . 1988 Jul; 188(3):308-15.
Score: 0.062
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Lincoln BC, Mayer A, Bonkovsky HL. Microassay of heme oxygenase by high-performance liquid chromatography: application to assay of needle biopsies of human liver. Anal Biochem. 1988 May 01; 170(2):485-90.
Score: 0.062
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Lincoln BC, Healey JF, Bonkovsky HL. Regulation of hepatic haem metabolism. Disparate mechanisms of induction of haem oxygenase by drugs and metals. Biochem J. 1988 Feb 15; 250(1):189-96.
Score: 0.061
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Bonkovsky HL, Healey JF, Lincoln B, Bacon BR, Bishop DF, Elder GH. Hepatic heme synthesis in a new model of experimental hemochromatosis: studies in rats fed finely divided elemental iron. Hepatology. 1987 Nov-Dec; 7(6):1195-203.
Score: 0.060
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Desai TK, Jamil LH, Balasubramaniam M, Koff R, Bonkovsky HL. Phlebotomy improves therapeutic response to interferon in patients with chronic hepatitis C: a meta-analysis of six prospective randomized controlled trials. Dig Dis Sci. 2008 Mar; 53(3):815-22.
Score: 0.059
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Bonkovsky HL, Lincoln B, Healey JF, Ou LC, Sinclair PR, Muller-Eberhard U. Hepatic heme and drug metabolism in rats with chronic mountain sickness. Am J Physiol. 1986 Oct; 251(4 Pt 1):G467-74.
Score: 0.055
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Bonkovsky HL, Naishadham D, Lambrecht RW, Chung RT, Hoefs JC, Nash SR, Rogers TE, Banner BF, Sterling RK, Donovan JA, Fontana RJ, Di Bisceglie AM, Ghany MG, Morishima C. Roles of iron and HFE mutations on severity and response to therapy during retreatment of advanced chronic hepatitis C. Gastroenterology. 2006 Nov; 131(5):1440-51.
Score: 0.055
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Sinclair PR, Sinclair JF, Bement WJ, Lambrecht RW, Bonkovsky HL. Induction of porphyria in cultured chick-embryo hepatocytes by halogenated aromatic compounds. IARC Sci Publ. 1986; (77):535-42.
Score: 0.052
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Elder GH, Urquhart AJ, De Salamanca RE, Munoz JJ, Bonkovsky HL. Immunoreactive uroporphyrinogen decarboxylase in the liver in porphyria cutanea tarda. Lancet. 1985 Aug 03; 2(8449):229-33.
Score: 0.051
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Bonkovsky HL, Healey JF, Sinclair PR, Sinclair JF. Conversion of 5-aminolaevulinate into haem by homogenates of human liver. Comparison with rat and chick-embryo liver homogenates. Biochem J. 1985 May 01; 227(3):893-901.
Score: 0.050
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Shan Y, Lambrecht RW, Bonkovsky HL. Association of hepatitis C virus infection with serum iron status: analysis of data from the third National Health and Nutrition Examination Survey. Clin Infect Dis. 2005 Mar 15; 40(6):834-41.
Score: 0.049
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Bonkovsky HL, Sinclair JF, Healey JF, Sinclair PR, Smith EL. Formation of cytochrome P-450 containing haem or cobalt-protoporphyrin in liver homogenates of rats treated with phenobarbital and allylisopropylacetamide. Biochem J. 1984 Sep 01; 222(2):453-62.
Score: 0.048
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Shedlofsky SI, Sinclair PR, Sinclair JF, Bonkovsky HL. Increased glutathione in cultured hepatocytes associated with induction of cytochrome P-450. Lack of effect of glutathione depletion on induction of cytochrome P-450 and delta-aminolevulinate synthase. Biochem Pharmacol. 1984 May 01; 33(9):1487-91.
Score: 0.047
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Bonkovsky HL, Lambrecht RW, Shan Y. Iron as a co-morbid factor in nonhemochromatotic liver disease. Alcohol. 2003 Jun; 30(2):137-44.
Score: 0.044
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Bonkovsky HL, Troy N, McNeal K, Banner BF, Sharma A, Obando J, Mehta S, Koff RS, Liu Q, Hsieh CC. Iron and HFE or TfR1 mutations as comorbid factors for development and progression of chronic hepatitis C. J Hepatol. 2002 Dec; 37(6):848-54.
Score: 0.042
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Balwani M, Sardh E, Ventura P, Peiró PA, Rees DC, Stölzel U, Bissell DM, Bonkovsky HL, Windyga J, Anderson KE, Parker C, Silver SM, Keel SB, Wang JD, Stein PE, Harper P, Vassiliou D, Wang B, Phillips J, Ivanova A, Langendonk JG, Kauppinen R, Minder E, Horie Y, Penz C, Chen J, Liu S, Ko JJ, Sweetser MT, Garg P, Vaishnaw A, Kim JB, Simon AR, Gouya L. Phase 3 Trial of RNAi Therapeutic Givosiran for Acute Intermittent Porphyria. N Engl J Med. 2020 06 11; 382(24):2289-2301.
Score: 0.036
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Fontana RJ, Israel J, LeClair P, Banner BF, Tortorelli K, Grace N, Levine RA, Fiarman G, Thiim M, Tavill AS, Bonkovsky HL. Iron reduction before and during interferon therapy of chronic hepatitis C: results of a multicenter, randomized, controlled trial. Hepatology. 2000 Mar; 31(3):730-6.
Score: 0.035
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Lambrecht RW, Gildemeister OS, Williams A, Pepe JA, Tortorelli KD, Bonkovsky HL. Effects of selected antihypertensives and analgesics on hepatic porphyrin accumulation: implications for clinical porphyria. Biochem Pharmacol. 1999 Sep 01; 58(5):887-96.
Score: 0.034
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Maitra D, Bragazzi Cunha J, Elenbaas JS, Bonkovsky HL, Shavit JA, Omary MB. Porphyrin-Induced Protein Oxidation and Aggregation as a Mechanism of Porphyria-Associated Cell Injury. Cell Mol Gastroenterol Hepatol. 2019; 8(4):535-548.
Score: 0.033
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Sardh E, Harper P, Balwani M, Stein P, Rees D, Bissell DM, Desnick R, Parker C, Phillips J, Bonkovsky HL, Vassiliou D, Penz C, Chan-Daniels A, He Q, Querbes W, Fitzgerald K, Kim JB, Garg P, Vaishnaw A, Simon AR, Anderson KE. Phase 1 Trial of an RNA Interference Therapy for Acute Intermittent Porphyria. N Engl J Med. 2019 02 07; 380(6):549-558.
Score: 0.033
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Giuggio VM, Bonkovsky HL, Smith J, Rothman AL. Inefficient recognition of autologous viral sequences by intrahepatic hepatitis C virus-specific cytotoxic T lymphocytes in chronically infected subjects. Virology. 1998 Nov 10; 251(1):132-40.
Score: 0.032
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Banner BF, Karamitsios N, Smith L, Bonkovsky HL. Enhanced phenotypic expression of alpha-1-antitrypsin deficiency in an MZ heterozygote with chronic hepatitis C. Am J Gastroenterol. 1998 Sep; 93(9):1541-5.
Score: 0.032
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Lu TH, Lambrecht RW, Pepe J, Shan Y, Kim T, Bonkovsky HL. Molecular cloning, characterization, and expression of the chicken heme oxygenase-1 gene in transfected primary cultures of chick embryo liver cells. Gene. 1998 Jan 30; 207(2):177-86.
Score: 0.030
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Kowdley KV, Trainer TD, Saltzman JR, Pedrosa M, Krawitt EL, Knox TA, Susskind K, Pratt D, Bonkovsky HL, Grace ND, Kaplan MM. Utility of hepatic iron index in American patients with hereditary hemochromatosis: a multicenter study. Gastroenterology. 1997 Oct; 113(4):1270-7.
Score: 0.030
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Lu TH, Pepe JA, Gildemeister OS, Tyrrell RM, Bonkovsky HL. Regulation of expression of the human heme oxygenase-1 gene in transfected chick embryo liver cell cultures. Biochim Biophys Acta. 1997 Jun 26; 1352(3):293-302.
Score: 0.029
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Bonkovsky HL, Banner BF, Rothman AL. Iron and chronic viral hepatitis. Hepatology. 1997 Mar; 25(3):759-68.
Score: 0.028
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Banner BF, Allan C, Smith L, Savas L, Bonkovsky HL. Effect of interferon therapy on bile duct inflammation in hepatitis C. Virchows Arch. 1996 Jul; 428(4-5):253-9.
Score: 0.027
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deLemos AS, Ghabril M, Rockey DC, Gu J, Barnhart HX, Fontana RJ, Kleiner DE, Bonkovsky HL. Amoxicillin-Clavulanate-Induced Liver Injury. Dig Dis Sci. 2016 08; 61(8):2406-2416.
Score: 0.027
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Bonkovsky HL, Banner BF, Lambrecht RW, Rubin RB. Iron in liver diseases other than hemochromatosis. Semin Liver Dis. 1996 Feb; 16(1):65-82.
Score: 0.026
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Banner BF, Barton AL, Cable EE, Smith L, Bonkovsky HL. A detailed analysis of the Knodell score and other histologic parameters as predictors of response to interferon therapy in chronic hepatitis C. Mod Pathol. 1995 Apr; 8(3):232-8.
Score: 0.025
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Seeff LB, Bonkovsky HL, Navarro VJ, Wang G. Herbal products and the liver: a review of adverse effects and mechanisms. Gastroenterology. 2015 Mar; 148(3):517-532.e3.
Score: 0.024
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Sinclair PR, Bement WJ, Healey JF, Gorman N, Sinclair JF, Bonkovsky HL, Liem HH, Muller-Eberhard U. Effects of hemopexin on heme-mediated repression of 5-aminolevulinate synthase and induction of heme oxygenase in cultured hepatocytes. Hepatology. 1994 Sep; 20(3):741-6.
Score: 0.024
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Li T, Eheim AL, Klein S, Uschner FE, Smith AC, Brandon-Warner E, Ghosh S, Bonkovsky HL, Trebicka J, Schrum LW. Novel role of nuclear receptor Rev-erba in hepatic stellate cell activation: potential therapeutic target for liver injury. Hepatology. 2014 Jun; 59(6):2383-96.
Score: 0.023
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Ghabril M, Bonkovsky HL, Kum C, Davern T, Hayashi PH, Kleiner DE, Serrano J, Rochon J, Fontana RJ, Bonacini M. Liver injury from tumor necrosis factor-a antagonists: analysis of thirty-four cases. Clin Gastroenterol Hepatol. 2013 May; 11(5):558-564.e3.
Score: 0.021
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Merrill AH, Wang E, LaRocque R, Mullins RE, Morgan ET, Hargrove JL, Bonkovsky HL, Popova IA. Differences in glycogen, lipids, and enzymes in livers from rats flown on COSMOS 2044. J Appl Physiol (1985). 1992 Aug; 73(2 Suppl):142S-147S.
Score: 0.021
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Morishima C, Di Bisceglie AM, Rothman AL, Bonkovsky HL, Lindsay KL, Lee WM, Koziel MJ, Fontana RJ, Kim HY, Wright EC. Antigen-specific T lymphocyte proliferation decreases over time in advanced chronic hepatitis C. J Viral Hepat. 2012 Jun; 19(6):404-13.
Score: 0.020
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Cable EE, Healey JF, Greene Y, Evans CO, Bonkovsky HL. Synergistic induction of delta-aminolevulinate synthase by glutethimide and iron: relationship to the synergistic induction of heme oxygenase. Biochim Biophys Acta. 1991 Nov 15; 1080(3):245-51.
Score: 0.020
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Morgan TR, Ghany MG, Kim HY, Snow KK, Shiffman ML, De Santo JL, Lee WM, Di Bisceglie AM, Bonkovsky HL, Dienstag JL, Morishima C, Lindsay KL, Lok AS. Outcome of sustained virological responders with histologically advanced chronic hepatitis C. Hepatology. 2010 Sep; 52(3):833-44.
Score: 0.018
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Cable E, Greene Y, Healey J, Evans CO, Bonkovsky H. Mechanism of synergistic induction of hepatic heme oxygenase by glutethimide and iron: studies in cultured chick embryo liver cells. Biochem Biophys Res Commun. 1990 Apr 16; 168(1):176-81.
Score: 0.018
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Goodman ZD, Stoddard AM, Bonkovsky HL, Fontana RJ, Ghany MG, Morgan TR, Wright EC, Brunt EM, Kleiner DE, Shiffman ML, Everson GT, Lindsay KL, Dienstag JL, Morishima C. Fibrosis progression in chronic hepatitis C: morphometric image analysis in the HALT-C trial. Hepatology. 2009 Dec; 50(6):1738-49.
Score: 0.017
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Lok AS, Sterling RK, Everhart JE, Wright EC, Hoefs JC, Di Bisceglie AM, Morgan TR, Kim HY, Lee WM, Bonkovsky HL, Dienstag JL. Des-gamma-carboxy prothrombin and alpha-fetoprotein as biomarkers for the early detection of hepatocellular carcinoma. Gastroenterology. 2010 Feb; 138(2):493-502.
Score: 0.017
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Di Bisceglie AM, Shiffman ML, Everson GT, Lindsay KL, Everhart JE, Wright EC, Lee WM, Lok AS, Bonkovsky HL, Morgan TR, Ghany MG, Morishima C, Snow KK, Dienstag JL. Prolonged therapy of advanced chronic hepatitis C with low-dose peginterferon. N Engl J Med. 2008 Dec 04; 359(23):2429-41.
Score: 0.016
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Lok AS, Seeff LB, Morgan TR, di Bisceglie AM, Sterling RK, Curto TM, Everson GT, Lindsay KL, Lee WM, Bonkovsky HL, Dienstag JL, Ghany MG, Morishima C, Goodman ZD. Incidence of hepatocellular carcinoma and associated risk factors in hepatitis C-related advanced liver disease. Gastroenterology. 2009 Jan; 136(1):138-48.
Score: 0.016
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Chalasani N, Fontana RJ, Bonkovsky HL, Watkins PB, Davern T, Serrano J, Yang H, Rochon J. Causes, clinical features, and outcomes from a prospective study of drug-induced liver injury in the United States. Gastroenterology. 2008 Dec; 135(6):1924-34, 1934.e1-4.
Score: 0.016
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Venkataraman K, Lee YM, Michaud J, Thangada S, Ai Y, Bonkovsky HL, Parikh NS, Habrukowich C, Hla T. Vascular endothelium as a contributor of plasma sphingosine 1-phosphate. Circ Res. 2008 Mar 28; 102(6):669-76.
Score: 0.015
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Shedlofsky SI, Sinclair PR, Bonkovsky HL, Healey JF, Swim AT, Robinson JM. Haem synthesis from exogenous 5-aminolaevulinate in cultured chick-embryo hepatocytes. Effects of inducers of cytochromes P-450. Biochem J. 1987 Nov 15; 248(1):229-36.
Score: 0.015
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Bonkovsky HL, Sinclair PR, Bement WJ, Lambrecht RW, Sinclair JF. Role of cytochrome P-450 in porphyria caused by halogenated aromatic compounds. Ann N Y Acad Sci. 1987; 514:96-112.
Score: 0.014
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Everson GT, Hoefs JC, Seeff LB, Bonkovsky HL, Naishadham D, Shiffman ML, Kahn JA, Lok AS, Di Bisceglie AM, Lee WM, Dienstag JL, Ghany MG, Morishima C. Impact of disease severity on outcome of antiviral therapy for chronic hepatitis C: Lessons from the HALT-C trial. Hepatology. 2006 Dec; 44(6):1675-84.
Score: 0.014
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Sinclair PR, Bement WJ, Bonkovsky HL, Lambrecht RW, Frezza JE, Sinclair JF, Urquhart AJ, Elder GH. Uroporphyrin accumulation produced by halogenated biphenyls in chick-embryo hepatocytes. Reversal of the accumulation by piperonyl butoxide. Biochem J. 1986 Jul 01; 237(1):63-71.
Score: 0.014
-
Bonkovsky HL, Wood SG, Howell SK, Sinclair PR, Lincoln B, Healey JF, Sinclair JF. High-performance liquid chromatographic separation and quantitation of tetrapyrroles from biological materials. Anal Biochem. 1986 May 15; 155(1):56-64.
Score: 0.013
-
Bonkovsky HL, Blanchette PL, Schned AR. Severe liver injury due to phenelzine with unique hepatic deposition of extracellular material. Am J Med. 1986 Apr; 80(4):689-92.
Score: 0.013
-
Sinclair JF, Zaitlin LM, Smith EL, Howell SK, Bonkovsky HL, Sinclair PR. Induction of 5-aminolaevulinate synthase by two- to five-carbon alcohols in cultured chick-embryo hepatocytes. Relationship to induction of cytochrome P-450. Biochem J. 1986 Mar 01; 234(2):405-11.
Score: 0.013
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Morishima C, Polyak SJ, Ray R, Doherty MC, Di Bisceglie AM, Malet PF, Bonkovsky HL, Sullivan DG, Gretch DR, Rothman AL, Koziel MJ, Lindsay KL. Hepatitis C virus-specific immune responses and quasi-species variability at baseline are associated with nonresponse to antiviral therapy during advanced hepatitis C. J Infect Dis. 2006 Apr 01; 193(7):931-40.
Score: 0.013
-
Bonkovsky HL, Schned AR. Fatal liver failure in protoporphyria. Synergism between ethanol excess and the genetic defect. Gastroenterology. 1986 Jan; 90(1):191-201.
Score: 0.013
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Bonkovsky HL, Hauri HP, Marti U, Gasser R, Meyer UA. Cytochrome P450 of small intestinal epithelial cells. Immunochemical characterization of the increase in cytochrome P450 caused by phenobarbital. Gastroenterology. 1985 Feb; 88(2):458-67.
Score: 0.012
-
Giuggio VM, Bonkovsky HL, Rothman AL. Evolution of the intrahepatic T cell repertoire during chronic hepatitis C virus infection. Viral Immunol. 2005; 18(1):179-89.
Score: 0.012
-
Sinclair PR, Bement WJ, Bonkovsky HL, Sinclair JF. Inhibition of uroporphyrinogen decarboxylase by halogenated biphenyls in chick hepatocyte cultures. Essential role for induction of cytochrome P-448. Biochem J. 1984 Sep 15; 222(3):737-48.
Score: 0.012
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Bonkovsky HL, Healey JF, Bement WJ, Sinclair PR, Sinclair JF, Shedlofsky SI. Effect of uroporphyrin on the spectral measurement of cytochrome P450. Biochem Pharmacol. 1984 Feb 01; 33(3):499-502.
Score: 0.011
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Mathai J, Shimoda K, Banner BF, Mori M, Bonkovsky HL, Barnard GF. IFN-alpha receptor mRNA expression in a United States sample with predominantly genotype 1a/I chronic hepatitis C liver biopsies correlates with response to IFN therapy. J Interferon Cytokine Res. 1999 Sep; 19(9):1011-8.
Score: 0.008