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Connection

Herbert Bonkovsky to Heme

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This is a "connection" page, showing publications Herbert Bonkovsky has written about Heme.
Herbert Bonkovsky
Connection Strength
6.322
Heme
  1. Bonkovsky HL, Dixon N, Rudnick S. Pathogenesis and clinical features of the acute hepatic porphyrias (AHPs). Mol Genet Metab. 2019 11; 128(3):213-218.
    View in: PubMed
    Score: 0.673
  2. Bonkovsky HL, Hou W, Steuerwald N, Tian Q, Li T, Parsons J, Hamilton A, Hwang S, Schrum L. Heme status affects human hepatic messenger RNA and microRNA expression. World J Gastroenterol. 2013 Mar 14; 19(10):1593-601.
    View in: PubMed
    Score: 0.445
  3. Bonkovsky HL, Guo JT, Hou W, Li T, Narang T, Thapar M. Porphyrin and heme metabolism and the porphyrias. Compr Physiol. 2013 Jan; 3(1):365-401.
    View in: PubMed
    Score: 0.439
  4. Tian Q, Li T, Hou W, Zheng J, Schrum LW, Bonkovsky HL. Lon peptidase 1 (LONP1)-dependent breakdown of mitochondrial 5-aminolevulinic acid synthase protein by heme in human liver cells. J Biol Chem. 2011 Jul 29; 286(30):26424-30.
    View in: PubMed
    Score: 0.394
  5. Kolluri S, Sadlon TJ, May BK, Bonkovsky HL. Haem repression of the housekeeping 5-aminolaevulinic acid synthase gene in the hepatoma cell line LMH. Biochem J. 2005 Nov 15; 392(Pt 1):173-80.
    View in: PubMed
    Score: 0.268
  6. Chemmanur AT, Bonkovsky HL. Hepatic porphyrias: diagnosis and management. Clin Liver Dis. 2004 Nov; 8(4):807-38, viii.
    View in: PubMed
    Score: 0.249
  7. Shan Y, Lambrecht RW, Bonkovsky HL. Identification of key elements that are responsible for heme-mediated induction of the avian heme oxygenase-1 gene. Biochim Biophys Acta. 2004 Aug 12; 1679(2):87-94.
    View in: PubMed
    Score: 0.245
  8. Do KD, Banner BF, Katz E, Szymanski IO, Bonkovsky HL. Benefits of chronic plasmapheresis and intravenous heme-albumin in erythropoietic protoporphyria after orthotopic liver transplantation. Transplantation. 2002 Feb 15; 73(3):469-72.
    View in: PubMed
    Score: 0.206
  9. Kolluri S, Elbirt KK, Bonkovsky HL. Heme biosynthesis in a chicken hepatoma cell line (LMH): comparison with primary chick embryo liver cells (CELC). Biochim Biophys Acta. 1999 Nov 16; 1472(3):658-67.
    View in: PubMed
    Score: 0.177
  10. Dixon N, Li T, Marion B, Faust D, Dozier S, Molina A, Rudnick S, Bonkovsky HL. Pilot study of mitochondrial bioenergetics in subjects with acute porphyrias. Mol Genet Metab. 2019 11; 128(3):228-235.
    View in: PubMed
    Score: 0.171
  11. Reichheld JH, Katz E, Banner BF, Szymanski IO, Saltzman JR, Bonkovsky HL. The value of intravenous heme-albumin and plasmapheresis in reducing postoperative complications of orthotopic liver transplantation for erythropoietic protoporphyria. Transplantation. 1999 Mar 27; 67(6):922-8.
    View in: PubMed
    Score: 0.169
  12. Pulgar VM, Yasuda M, Gan L, Desnick RJ, Bonkovsky HL. Sex differences in vascular reactivity in mesenteric arteries from a mouse model of acute intermittent porphyria. Mol Genet Metab. 2019 11; 128(3):376-381.
    View in: PubMed
    Score: 0.166
  13. Bissell DM, Anderson KE, Bonkovsky HL. Porphyria. N Engl J Med. 2017 Aug 31; 377(9):862-872.
    View in: PubMed
    Score: 0.152
  14. Bonkovsky HL, Gildemeister OS, Pepe JA, Lambrecht RW, Hrkal Z. Haemopexin and uptake of haem by liver cells. Eur J Clin Chem Clin Biochem. 1996 Nov; 34(11):931-2.
    View in: PubMed
    Score: 0.143
  15. Cable EE, Gildemeister OS, Pepe JA, Donohue SE, Lambrecht RW, Bonkovsky HL. Hepatic 5-aminolevulinic acid synthase mRNA stability is modulated by inhibitors of heme biosynthesis and by metalloporphyrins. Eur J Biochem. 1996 Aug 15; 240(1):112-7.
    View in: PubMed
    Score: 0.141
  16. Cable EE, Pepe JA, Donohue SE, Lambrecht RW, Bonkovsky HL. Effects of mifepristone (RU-486) on heme metabolism and cytochromes P-450 in cultured chick embryo liver cells, possible implications for acute porphyria. Eur J Biochem. 1994 Oct 15; 225(2):651-7.
    View in: PubMed
    Score: 0.124
  17. Russo SM, Pepe JA, Cable EE, Lambrecht RW, Bonkovsky HL. Repression of ALA synthase by heme and zinc-mesoporphyrin in a chick embryo liver cell culture model of acute porphyria. Eur J Clin Invest. 1994 Jun; 24(6):406-15.
    View in: PubMed
    Score: 0.121
  18. Cable EE, Cable JW, Bonkovsky HL. Repression of hepatic delta-aminolevulinate synthase by heme and metalloporphyrins: relationship to inhibition of heme oxygenase. Hepatology. 1993 Jul; 18(1):119-27.
    View in: PubMed
    Score: 0.114
  19. Larion S, Caballes FR, Hwang SI, Lee JG, Rossman WE, Parsons J, Steuerwald N, Li T, Maddukuri V, Groseclose G, Finkielstein CV, Bonkovsky HL. Circadian rhythms in acute intermittent porphyria--a pilot study. Eur J Clin Invest. 2013 Jul; 43(7):727-39.
    View in: PubMed
    Score: 0.112
  20. Srivastava KK, Cable EE, Donohue SE, Bonkovsky HL. Molecular basis for heme-dependent induction of heme oxygenase in primary cultures of chick embryo hepatocytes. Demonstration of acquired refractoriness to heme. Eur J Biochem. 1993 May 01; 213(3):909-17.
    View in: PubMed
    Score: 0.112
  21. Lincoln BC, Aw TY, Bonkovsky HL. Heme catabolism in cultured hepatocytes: evidence that heme oxygenase is the predominant pathway and that a proportion of synthesized heme is converted rapidly to biliverdin. Biochim Biophys Acta. 1989 Jul 21; 992(1):49-58.
    View in: PubMed
    Score: 0.086
  22. Zheng J, Shan Y, Lambrecht RW, Donohue SE, Bonkovsky HL. Differential regulation of human ALAS1 mRNA and protein levels by heme and cobalt protoporphyrin. Mol Cell Biochem. 2008 Dec; 319(1-2):153-61.
    View in: PubMed
    Score: 0.081
  23. Bonkovsky HL, Siao P, Roig Z, Hedley-Whyte ET, Flotte TJ. Case records of the Massachusetts General Hospital. Case 20-2008. A 57-year-old woman with abdominal pain and weakness after gastric bypass surgery. N Engl J Med. 2008 Jun 26; 358(26):2813-25.
    View in: PubMed
    Score: 0.080
  24. Zheng J, Tian Q, Hou W, Watts JA, Schrum LW, Bonkovsky HL. Tissue-specific expression of ALA synthase-1 and heme oxygenase-1 and their expression in livers of rats chronically exposed to ethanol. FEBS Lett. 2008 Jun 11; 582(13):1829-34.
    View in: PubMed
    Score: 0.079
  25. Lincoln BC, Healey JF, Bonkovsky HL. Regulation of hepatic haem metabolism. Disparate mechanisms of induction of haem oxygenase by drugs and metals. Biochem J. 1988 Feb 15; 250(1):189-96.
    View in: PubMed
    Score: 0.078
  26. Hou W, Shan Y, Zheng J, Lambrecht RW, Donohue SE, Bonkovsky HL. Zinc mesoporphyrin induces rapid and marked degradation of the transcription factor Bach1 and up-regulates HO-1. Biochim Biophys Acta. 2008 Mar; 1779(3):195-203.
    View in: PubMed
    Score: 0.078
  27. Bonkovsky HL, Healey JF, Lincoln B, Bacon BR, Bishop DF, Elder GH. Hepatic heme synthesis in a new model of experimental hemochromatosis: studies in rats fed finely divided elemental iron. Hepatology. 1987 Nov-Dec; 7(6):1195-203.
    View in: PubMed
    Score: 0.077
  28. Shan Y, Zheng J, Lambrecht RW, Bonkovsky HL. Reciprocal effects of micro-RNA-122 on expression of heme oxygenase-1 and hepatitis C virus genes in human hepatocytes. Gastroenterology. 2007 Oct; 133(4):1166-74.
    View in: PubMed
    Score: 0.075
  29. Lambrecht RW, Thapar M, Bonkovsky HL. Genetic aspects of porphyria cutanea tarda. Semin Liver Dis. 2007 Feb; 27(1):99-108.
    View in: PubMed
    Score: 0.073
  30. Bonkovsky HL, Lincoln B, Healey JF, Ou LC, Sinclair PR, Muller-Eberhard U. Hepatic heme and drug metabolism in rats with chronic mountain sickness. Am J Physiol. 1986 Oct; 251(4 Pt 1):G467-74.
    View in: PubMed
    Score: 0.071
  31. Bonkovsky HL, Wood SG, Howell SK, Sinclair PR, Lincoln B, Healey JF, Sinclair JF. High-performance liquid chromatographic separation and quantitation of tetrapyrroles from biological materials. Anal Biochem. 1986 May 15; 155(1):56-64.
    View in: PubMed
    Score: 0.069
  32. Bonkovsky HL, Healey JF, Sinclair PR, Sinclair JF. Conversion of 5-aminolaevulinate into haem by homogenates of human liver. Comparison with rat and chick-embryo liver homogenates. Biochem J. 1985 May 01; 227(3):893-901.
    View in: PubMed
    Score: 0.064
  33. Bonkovsky HL. Neurovisceral porphyrias: what a hematologist needs to know. Hematology Am Soc Hematol Educ Program. 2005; 24-30.
    View in: PubMed
    Score: 0.063
  34. Shan Y, Lambrecht RW, Ghaziani T, Donohue SE, Bonkovsky HL. Role of Bach-1 in regulation of heme oxygenase-1 in human liver cells: insights from studies with small interfering RNAS. J Biol Chem. 2004 Dec 10; 279(50):51769-74.
    View in: PubMed
    Score: 0.062
  35. Bonkovsky HL, Sinclair JF, Healey JF, Sinclair PR, Smith EL. Formation of cytochrome P-450 containing haem or cobalt-protoporphyrin in liver homogenates of rats treated with phenobarbital and allylisopropylacetamide. Biochem J. 1984 Sep 01; 222(2):453-62.
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    Score: 0.062
  36. Shan Y, Pepe J, Lambrecht RW, Bonkovsky HL. Mapping of the chick heme oxygenase-1 proximal promoter for responsiveness to metalloporphyrins. Arch Biochem Biophys. 2002 Mar 15; 399(2):159-66.
    View in: PubMed
    Score: 0.052
  37. Shan Y, Pepe J, Lu TH, Elbirt KK, Lambrecht RW, Bonkovsky HL. Induction of the heme oxygenase-1 gene by metalloporphyrins. Arch Biochem Biophys. 2000 Aug 15; 380(2):219-27.
    View in: PubMed
    Score: 0.046
  38. Elbirt KK, Bonkovsky HL. Heme oxygenase: recent advances in understanding its regulation and role. Proc Assoc Am Physicians. 1999 Sep-Oct; 111(5):438-47.
    View in: PubMed
    Score: 0.044
  39. Maitra D, Bragazzi Cunha J, Elenbaas JS, Bonkovsky HL, Shavit JA, Omary MB. Porphyrin-Induced Protein Oxidation and Aggregation as a Mechanism of Porphyria-Associated Cell Injury. Cell Mol Gastroenterol Hepatol. 2019; 8(4):535-548.
    View in: PubMed
    Score: 0.043
  40. Elbirt KK, Whitmarsh AJ, Davis RJ, Bonkovsky HL. Mechanism of sodium arsenite-mediated induction of heme oxygenase-1 in hepatoma cells. Role of mitogen-activated protein kinases. J Biol Chem. 1998 Apr 10; 273(15):8922-31.
    View in: PubMed
    Score: 0.040
  41. Lu TH, Pepe JA, Gildemeister OS, Tyrrell RM, Bonkovsky HL. Regulation of expression of the human heme oxygenase-1 gene in transfected chick embryo liver cell cultures. Biochim Biophys Acta. 1997 Jun 26; 1352(3):293-302.
    View in: PubMed
    Score: 0.037
  42. Cable EE, Gildemeister OS, Pepe JA, Lambrecht RW, Bonkovsky HL. Mechanism of induction of heme oxygenase by metalloporphyrins in primary chick embryo liver cells: evidence against a stress-mediated response. Mol Cell Biochem. 1997 Apr; 169(1-2):13-20.
    View in: PubMed
    Score: 0.037
  43. Bonkovsky HL, Ponka P, Bacon BR, Drysdale J, Grace ND, Tavill AS. An update on iron metabolism: summary of the Fifth International Conference on Disorders of Iron Metabolism. Hepatology. 1996 Sep; 24(3):718-29.
    View in: PubMed
    Score: 0.035
  44. Gabis KK, Gildemeister OS, Pepe JA, Lambrecht RW, Bonkovsky HL. Induction of heme oxygenase-1 in LMH cells. Comparison of LMH cells to primary cultures of chick embryo liver cells. Biochim Biophys Acta. 1996 May 21; 1290(1):113-20.
    View in: PubMed
    Score: 0.035
  45. Sinclair PR, Bement WJ, Healey JF, Gorman N, Sinclair JF, Bonkovsky HL, Liem HH, Muller-Eberhard U. Effects of hemopexin on heme-mediated repression of 5-aminolevulinate synthase and induction of heme oxygenase in cultured hepatocytes. Hepatology. 1994 Sep; 20(3):741-6.
    View in: PubMed
    Score: 0.031
  46. Pinnix IB, Guzman GS, Bonkovsky HL, Zaki SR, Kinkade JM. The post-translational processing of myeloperoxidase is regulated by the availability of heme. Arch Biochem Biophys. 1994 Aug 01; 312(2):447-58.
    View in: PubMed
    Score: 0.031
  47. Lambrecht RW, Cable JW, Pepe JA, Bonkovsky HL. 3,5,5-Trimethylhexanoylferrocene induction of heme oxygenase activity in normal hepatocytes. Biochem Pharmacol. 1994 Apr 29; 47(9):1669-76.
    View in: PubMed
    Score: 0.030
  48. Bonkovsky HL. Advances in understanding and treating 'the little imitator,' acute porphyria. Gastroenterology. 1993 Aug; 105(2):590-4.
    View in: PubMed
    Score: 0.029
  49. Cable EE, Healey JF, Greene Y, Evans CO, Bonkovsky HL. Synergistic induction of delta-aminolevulinate synthase by glutethimide and iron: relationship to the synergistic induction of heme oxygenase. Biochim Biophys Acta. 1991 Nov 15; 1080(3):245-51.
    View in: PubMed
    Score: 0.025
  50. Li T, Bonkovsky HL, Guo JT. Structural analysis of heme proteins: implications for design and prediction. BMC Struct Biol. 2011 Mar 03; 11:13.
    View in: PubMed
    Score: 0.024
  51. Bloomer JR, Bonkovsky HL. The porphyrias. Dis Mon. 1989 Jan; 35(1):1-54.
    View in: PubMed
    Score: 0.021
  52. Lincoln BC, Alvarado A, Setty N, Bonkovsky HL. Tryptophan 2,3-dioxygenase in chick embryo hepatocytes: studies in ovo and in culture. . 1988 Jul; 188(3):308-15.
    View in: PubMed
    Score: 0.020
  53. Shedlofsky SI, Sinclair PR, Bonkovsky HL, Healey JF, Swim AT, Robinson JM. Haem synthesis from exogenous 5-aminolaevulinate in cultured chick-embryo hepatocytes. Effects of inducers of cytochromes P-450. Biochem J. 1987 Nov 15; 248(1):229-36.
    View in: PubMed
    Score: 0.019
  54. Sinclair PR, Bement WJ, Bonkovsky HL, Lambrecht RW, Frezza JE, Sinclair JF, Urquhart AJ, Elder GH. Uroporphyrin accumulation produced by halogenated biphenyls in chick-embryo hepatocytes. Reversal of the accumulation by piperonyl butoxide. Biochem J. 1986 Jul 01; 237(1):63-71.
    View in: PubMed
    Score: 0.004
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