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Stephen M. Downs MD, MS

TitleProfessor
InstitutionWake Forest School of Medicine
DepartmentPediatrics, General
Address
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    Collapse education and training
    Stanford University, Stanford, CAMS06/1986Medical Informatics
    Stanford University, Stanford, CAMD06/1986Medicine
    University of North Carolina, Chapel Hill, NC06/1989Pediatrics
    University of North Carolina, Chapel Hill, NC06/1991Health Services Research

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Jones LD, Grout RW, Gilbert AL, Wilkinson TA, Garbuz T, Downs SM, Aalsma MC. How can healthcare professionals provide guidance and support to parents of adolescents? Results from a primary care-based study. BMC Health Serv Res. 2021 Mar 20; 21(1):253. PMID: 33743664.
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    2. Grout RW, Buchhalter J, Patel AD, Brin A, Clark AA, Holmay M, Story TJ, Downs SM. Improving Patient-Centered Communication about Sudden Unexpected Death in Epilepsy through Computerized Clinical Decision Support. Appl Clin Inform. 2021 01; 12(1):90-99. PMID: 33598905.
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    3. Downs SM. Interval Likelihood Ratios and the Diagnostic Process. Pediatrics. 2021 01; 147(1). PMID: 33277352.
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    4. Scott EK, Downs SM, Pottenger AK, Bien JP, Saysana MS. Enhancing Safe Sleep Counseling by Pediatricians through a Quality Improvement Learning Collaborative. Pediatr Qual Saf. 2020 Jul-Aug; 5(4):e327. PMID: 32766498.
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    5. El Mikati HK, Yazel-Smith L, Grout RW, Downs SM, Carroll AE, Hannon TS. Clinician Perceptions of a Computerized Decision Support System for Pediatric Type 2 Diabetes Screening. Appl Clin Inform. 2020 03; 11(2):350-355. PMID: 32403140.
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    6. Salama A, Panoch J, Bandali E, Carroll A, Wiehe S, Downs S, Cain MP, Frankel R, Chan KH. Consulting "Dr. YouTube": an objective evaluation of hypospadias videos on a popular video-sharing website. J Pediatr Urol. 2020 Feb; 16(1):70.e1-70.e9. PMID: 31928900.
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    7. Downs SM, Bauer NS, Saha C, Ofner S, Carroll AE. Effect of a Computer-Based Decision Support Intervention on Autism Spectrum Disorder Screening in Pediatric Primary Care Clinics: A Cluster Randomized Clinical Trial. JAMA Netw Open. 2019 12 02; 2(12):e1917676. PMID: 31851348.
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    8. Scott E, Downs S, Pottenger A, Saysana M. Quality Improvement Learning Collaborative Improves Timely Newborn Follow-Up Appointments. Jt Comm J Qual Patient Saf. 2019 12; 45(12):808-813. PMID: 31607501.
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    9. Tucker Edmonds B, McKenzie F, Downs SM, Carroll AE. Women's Preferences for Maternal and Neonatal Morbidity and Mortality in Childbirth. Med Decis Making. 2019 10; 39(7):755-764. PMID: 31556790.
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    10. Stafford AM, Garbuz T, Etter DJ, Adams ZW, Hulvershorn LA, Downs SM, Aalsma MC. The Natural Course of Adolescent Depression Treatment in the Primary Care Setting. J Pediatr Health Care. 2020 Jan - Feb; 34(1):38-46. PMID: 31548140.
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    11. Ferrin SN, Grout RW, Gilbert AL, Wilkinson TA, Cheng ER, Downs SM, Aalsma MC. Caregiver Comfort in Adolescents Independently Completing Screening Tablet-Based Questionnaires at Primary Care Visits. J Adolesc Health. 2019 12; 65(6):799-804. PMID: 31522906.
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    12. Wilkinson TA, Downs SM, Tucker Edmonds B. Cost Minimization Analysis of Same-Day Long-Acting Reversible Contraception for Adolescents. JAMA Netw Open. 2019 09 04; 2(9):e1911063. PMID: 31509208.
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    13. Wilkinson TA, Dixon BE, Xiao S, Tu W, Lindsay B, Sheley M, Dugan T, Church A, Downs SM, Zimet G. Physician clinical decision support system prompts and administration of subsequent doses of HPV vaccine: A randomized clinical trial. Vaccine. 2019 07 18; 37(31):4414-4418. PMID: 31201057.
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    14. Grout RW, Cheng ER, Aalsma MC, Downs SM. Let Them Speak for Themselves: Improving Adolescent Self-Report Rate on Pre-Visit Screening. Acad Pediatr. 2019 07; 19(5):581-588. PMID: 31029741.
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    15. Honaker SM, Street A, Daftary AS, Downs SM. The Use of Computer Decision Support for Pediatric Obstructive Sleep Apnea Detection in Primary Care. J Clin Sleep Med. 2019 03 15; 15(3):453-462. PMID: 30853049.
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    16. Bauer NS, Ofner S, Moore C, Lynch D, Wiehe SE, Downs SM, Carroll AE, Kronenberger WG. Assessment of the Effects of Pediatric Attention Deficit Hyperactivity Disorder on Family Stress and Well-Being: Development of the IMPACT 1.0 Scale. Glob Pediatr Health. 2019; 6:2333794X19835645. PMID: 30906819.
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    17. Chan KH, Whittam BM, Krambeck A, Downs SM, Misseri R, Cain MP, Bennett WE. Cost-Effectiveness Analysis of the Management of Distal Ureteral Stones in Children. Urology. 2019 05; 127:107-112. PMID: 30790649.
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    18. Hentea C, Downs SM, Tucker Edmonds B, Vik T, Wiehe SE, Cheng ER. Impact of socioeconomic markers on parents' retention of pediatric oncology home care education: A pilot study. Pediatr Blood Cancer. 2019 05; 66(5):e27624. PMID: 30693652.
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    19. Dixon BE, Zimet GD, Xiao S, Tu W, Lindsay B, Church A, Downs SM. An Educational Intervention to Improve HPV Vaccination: A Cluster Randomized Trial. Pediatrics. 2019 01; 143(1). PMID: 30530637.
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    20. Grout RW, Thompson-Fleming R, Carroll AE, Downs SM. Prevalence of pain reports in pediatric primary care and association with demographics, body mass index, and exam findings: a cross-sectional study. BMC Pediatr. 2018 11 21; 18(1):363. PMID: 30463543.
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    21. Cheng ER, Downs SM, Carroll AE. Prevalence of Depression Among Fathers at the Pediatric Well-Child Care Visit. JAMA Pediatr. 2018 09 01; 172(9):882-883. PMID: 30039168.
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    22. Downs SM. More Prescriptions, More Problems: Can Information Technology Help? Pediatrics. 2018 09; 142(3). PMID: 30150208.
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    23. Lehmann HP, Downs SM. Desiderata for sharable computable biomedical knowledge for learning health systems. Learn Health Syst. 2018 Oct; 2(4):e10065. PMID: 31245589.
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    24. Bauer NS, Sullivan PD, Szczepaniak D, Stelzner SM, Pottenger A, Ofner S, Downs SM, Carroll AE. Attention Deficit-Hyperactivity Disorder Group Visits Improve Parental Emotional Health and Perceptions of Child Behavior. J Dev Behav Pediatr. 2018 Jul/Aug; 39(6):461-470. PMID: 29877990.
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    25. Lewis Gilbert A, McCord AL, Ouyang F, Etter DJ, Williams RL, Hall JA, Tu W, Downs SM, Aalsma MC. Characteristics Associated with Confidential Consultation for Adolescents in Primary Care. J Pediatr. 2018 08; 199:79-84.e1. PMID: 29631769.
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    26. Zimet G, Dixon BE, Xiao S, Tu W, Kulkarni A, Dugan T, Sheley M, Downs SM. Simple and Elaborated Clinician Reminder Prompts for Human Papillomavirus Vaccination: A Randomized Clinical Trial. Acad Pediatr. 2018 03; 18(2S):S66-S71. PMID: 29502640.
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    27. Grout RW, Cheng ER, Carroll AE, Bauer NS, Downs SM. A six-year repeated evaluation of computerized clinical decision support system user acceptability. Int J Med Inform. 2018 04; 112:74-81. PMID: 29500025.
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    28. Honaker SM, Dugan T, Daftary A, Davis S, Saha C, Baye F, Freeman E, Downs SM. Unexplained Practice Variation in Primary Care Providers' Concern for Pediatric Obstructive Sleep Apnea. Acad Pediatr. 2018 May - Jun; 18(4):418-424. PMID: 29391284.
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    29. Etter DJ, McCord A, Ouyang F, Gilbert AL, Williams RL, Hall JA, Tu W, Downs SM, Aalsma MC. Suicide Screening in Primary Care: Use of an Electronic Screener to Assess Suicidality and Improve Provider Follow-Up for Adolescents. J Adolesc Health. 2018 02; 62(2):191-197. PMID: 29195764.
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    30. Aalsma MC, Zerr AM, Etter DJ, Ouyang F, Gilbert AL, Williams RL, Hall JA, Downs SM. Physician Intervention to Positive Depression Screens Among Adolescents in Primary Care. J Adolesc Health. 2018 02; 62(2):212-218. PMID: 29174939.
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    31. Bauer NS, Ofner S, Pottenger A, Carroll AE, Downs SM. Follow-up of Mothers with Suspected Postpartum Depression from Pediatrics Clinics. Front Pediatr. 2017; 5:212. PMID: 29043246.
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    32. Bauer NS, Azer N, Sullivan PD, Szczepaniak D, Stelzner SM, Downs SM, Carroll AE. Acceptability of Group Visits for Attention-Deficit Hyperactivity Disorder in Pediatric Clinics. J Dev Behav Pediatr. 2017 Oct; 38(8):565-572. PMID: 28816910.
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    33. Dixon BE, Kasting ML, Wilson S, Kulkarni A, Zimet GD, Downs SM. Health care providers' perceptions of use and influence of clinical decision support reminders: qualitative study following a randomized trial to improve HPV vaccination rates. BMC Med Inform Decis Mak. 2017 Aug 10; 17(1):119. PMID: 28797293.
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    34. Carroll AE, Saha C, Ofner S, Downs SM. Valuing health for oneself versus one's child or elderly parent. J Health Psychol. 2019 12; 24(14):1965-1975. PMID: 28810465.
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    35. Hannon TS, Dugan TM, Saha CK, McKee SJ, Downs SM, Carroll AE. Effectiveness of Computer Automation for the Diagnosis and Management of Childhood Type 2 Diabetes: A Randomized Clinical Trial. JAMA Pediatr. 2017 04 01; 171(4):327-334. PMID: 28192551.
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    36. Kunkel MD, Downs SM, Tucker Edmonds B. Influence of Maternal Factors in Neonatologists' Counseling for Periviable Pregnancies. Am J Perinatol. 2017 07; 34(8):787-794. PMID: 28192814.
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    37. Kasting ML, Wilson S, Dixon BE, Downs SM, Kulkarni A, Zimet GD. Healthcare providers' beliefs and attitudes regarding risk compensation following HPV vaccination. Papillomavirus Res. 2016 12; 2:116-121. PMID: 27441302.
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    38. Bauer NS, Yoder R, Carroll AE, Downs SM. Racial/Ethnic Differences in the Prevalence of Anxiety Using the Vanderbilt ADHD Scale in a Diverse Community Outpatient Setting. J Dev Behav Pediatr. 2016 10; 37(8):610-8. PMID: 27541582.
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    39. Brown LW, Camfield P, Capers M, Cascino G, Ciccarelli M, de Gusmao CM, Downs SM, Majnemer A, Miller AB, SanInocencio C, Schultz R, Tilton A, Winokur A, Zupanc M. The neurologist's role in supporting transition to adult health care: A consensus statement. Neurology. 2016 Aug 23; 87(8):835-40. PMID: 27466477.
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    40. Cheng ER, Bauer NS, Downs SM, Sanders LM. Parent Health Literacy, Depression, and Risk for Pediatric Injury. Pediatrics. 2016 07; 138(1). PMID: 27273749.
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    41. Goddard AW, Schwartz K, Hendrix K, Aalsma MC, Slaven J, Hancock EF, Lambert D, Downs S, Rosenman M. Trends in Use and Cost of Second-Generation Antipsychotics Among Children and Teens in Indiana Medicaid, 2004-2012. Psychiatr Serv. 2016 09 01; 67(9):1030-4. PMID: 27181731.
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    42. Kasting ML, Wilson S, Dixon BE, Downs SM, Kulkarni A, Zimet GD. A qualitative study of healthcare provider awareness and informational needs regarding the nine-valent HPV vaccine. Vaccine. 2016 Mar 08; 34(11):1331-4. PMID: 26859240.
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    43. Benneyworth BD, Downs SM, Nitu M. Retrospective Evaluation of the Epidemiology and Practice Variation of Dexmedetomidine Use in Invasively Ventilated Pediatric Intensive Care Admissions, 2007-2013. Front Pediatr. 2015; 3:109. PMID: 26734592.
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    44. Bauer NS, Carroll AE, Saha C, Downs SM. Experience with decision support system and comfort with topic predict clinicians' responses to alerts and reminders. J Am Med Inform Assoc. 2016 Apr; 23(e1):e125-30. PMID: 26567326.
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    45. Bauer NS, Szczepaniak D, Sullivan PD, Mooneyham G, Pottenger A, Johnson CS, Downs SM. Group Visits to Improve Pediatric Attention-Deficit Hyperactivity Disorder Chronic Care Management. J Dev Behav Pediatr. 2015 Oct; 36(8):553-61. PMID: 26414089.
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    46. Anand V, Carroll AE, Biondich PG, Dugan TM, Downs SM. Pediatric decision support using adapted Arden Syntax. Artif Intell Med. 2018 11; 92:15-23. PMID: 26547523.
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    47. Gilbert AL, Downs SM. Medical legal partnership and health informatics impacting child health: Interprofessional innovations. J Interprof Care. 2015; 29(6):564-9. PMID: 26120893.
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    48. Liu GC, Odell JD, Whipple EC, Ralston R, Carroll AE, Downs SM. Data visualization for truth maintenance in clinical decision support systems. Int J Pediatr Adolesc Med. 2015 Jun; 2(2):64-69. PMID: 30805439.
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    49. Valsangkar DS, Downs SM. Acetyl CoA carboxylase inactivation and meiotic maturation in mouse oocytes. Mol Reprod Dev. 2015 Sep; 82(9):679-93. PMID: 26043180.
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    50. Downs SM. Nutrient pathways regulating the nuclear maturation of mammalian oocytes. Reprod Fertil Dev. 2015 May; 27(4):572-82. PMID: 25798589.
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    51. Liu GC, Hannon T, Qi R, Downs SM, Marrero DG. The obesity epidemic in children: Latino children are disproportionately affected at younger ages. Int J Pediatr Adolesc Med. 2015 Mar; 2(1):12-18. PMID: 30805430.
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    52. Cristea AI, Ackerman VL, Davis SD, Carroll AE, Downs SM, Yu Z, Slaven JE, Swigonski NL. Median Household Income: Association with Mortality in Children on Chronic Ventilation at Home Secondary to Bronchopulmonary Dysplasia. Pediatr Allergy Immunol Pulmonol. 2015 Mar 01; 28(1):41-46. PMID: 25852968.
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    53. Hendrix KS, Downs SM, Carroll AE. Pediatricians' responses to printed clinical reminders: does highlighting prompts improve responsiveness? Acad Pediatr. 2015 Mar-Apr; 15(2):158-64. PMID: 25619917.
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    54. Hendrix KS, Downs SM. General practice web-based decision aid improves MMR vaccination uptake. Evid Based Nurs. 2015 Jul; 18(3):82. PMID: 25563638.
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    55. Finnell SM, Rosenman MB, Christenson JC, Downs SM. Decolonization of children after incision and drainage for MRSA abscess: a retrospective cohort study. Clin Pediatr (Phila). 2015 May; 54(5):445-50. PMID: 25385929.
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    56. Carroll AE, Bauer NS, Dugan TM, Anand V, Saha C, Downs SM. Use of a computerized decision aid for developmental surveillance and screening: a randomized clinical trial. JAMA Pediatr. 2014 Sep; 168(9):815-21. PMID: 25022724.
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    57. Hendrix KS, Finnell SM, Zimet GD, Sturm LA, Lane KA, Downs SM. Vaccine message framing and parents' intent to immunize their infants for MMR. Pediatrics. 2014 Sep; 134(3):e675-83. PMID: 25136038.
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    58. Bennett WE, Hendrix KS, Thompson RT, Carroll AE, Downs SM. The natural history of weight percentile changes in the first year of life. JAMA Pediatr. 2014 Jul; 168(7):681-2. PMID: 24797161.
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    59. Oshimura JM, Downs SM, Saysana M. Family-centered rounding: can it impact the time of discharge and time of completion of studies at an academic children's hospital? Hosp Pediatr. 2014 Jul; 4(4):228-32. PMID: 24986992.
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    60. Bauer NS, Anand V, Carroll AE, Downs SM. Secondhand smoke exposure, parental depressive symptoms and preschool behavioral outcomes. J Pediatr Nurs. 2015 Jan-Feb; 30(1):227-35. PMID: 25017291.
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    61. Downs S, Marquez J, Chiarelli P. Normative scores on the Berg Balance Scale decline after age 70 years in healthy community-dwelling people: a systematic review. J Physiother. 2014 Jun; 60(2):85-9. PMID: 24952835.
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    62. Goldshore MA, Solomon BS, Downs SM, Pan R, Minkovitz CS. Residency exposures and anticipated future involvement in community settings. Acad Pediatr. 2014 Jul-Aug; 14(4):341-7. PMID: 24906986.
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    63. Anand V, Downs SM, Bauer NS, Carroll AE. Prevalence of infant television viewing and maternal depression symptoms. J Dev Behav Pediatr. 2014 Apr; 35(3):216-24. PMID: 24633063.
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    64. Hendrix KS, Carroll AE, Downs SM. Screen exposure and body mass index status in 2- to 11-year-old children. Clin Pediatr (Phila). 2014 Jun; 53(6):593-600. PMID: 24634433.
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    65. Downs SM. UTI and watchful waiting: the courage to do nothing. Pediatrics. 2014 Mar; 133(3):535-6. PMID: 24515509.
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    66. Bennett WE, Hendrix KS, Thompson-Fleming RT, Downs SM, Carroll AE. Early cow's milk introduction is associated with failed personal-social milestones after 1 year of age. Eur J Pediatr. 2014 Jul; 173(7):887-92. PMID: 24458583.
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    67. Klann JG, Szolovits P, Downs SM, Schadow G. Decision support from local data: creating adaptive order menus from past clinician behavior. J Biomed Inform. 2014 Apr; 48:84-93. PMID: 24355978.
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    68. Papic JC, Finnell SM, Leys CM, Bennett WE, Downs SM. Referring physicians' decision making for pediatric anti-reflux procedures. Surgery. 2014 May; 155(5):851-9. PMID: 24787112.
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    69. Gilbert AL, Bauer NS, Carroll AE, Downs SM. Child exposure to parental violence and psychological distress associated with delayed milestones. Pediatrics. 2013 Dec; 132(6):e1577-83. PMID: 24190682.
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    70. Hendrix KS, Meslin EM, Carroll AE, Downs SM. Attitudes about the use of newborn dried blood spots for research: a survey of underrepresented parents. Acad Pediatr. 2013 Sep-Oct; 13(5):451-7. PMID: 24011748.
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    71. Anand V, Downs SM. Racial, Ethnic, and Language Disparities in Children's Exposure to Secondhand Smoke. Pediatr Allergy Immunol Pulmonol. 2013 Sep; 26(3):144-151. PMID: 24066263.
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    72. Valsangkar D, Downs SM. A requirement for fatty acid oxidation in the hormone-induced meiotic maturation of mouse oocytes. Biol Reprod. 2013 Aug; 89(2):43. PMID: 23863407.
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    73. Carroll AE, Bauer NS, Dugan TM, Anand V, Saha C, Downs SM. Use of a computerized decision aid for ADHD diagnosis: a randomized controlled trial. Pediatrics. 2013 Sep; 132(3):e623-9. PMID: 23958768.
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    74. Hendrix KS, Downs SM, Brophy G, Carney Doebbeling C, Swigonski NL. Threshold analysis of reimbursing physicians for the application of fluoride varnish in young children. J Public Health Dent. 2013; 73(4):297-303. PMID: 23889556.
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    75. Klann JG, Anand V, Downs SM. Patient-tailored prioritization for a pediatric care decision support system through machine learning. J Am Med Inform Assoc. 2013 Dec; 20(e2):e267-74. PMID: 23886921.
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    76. Szczepaniak D, McHenry MS, Nutakki K, Bauer NS, Downs SM. The prevalence of at-risk development in children 30 to 60 months old presenting with disruptive behaviors. Clin Pediatr (Phila). 2013 Oct; 52(10):942-9. PMID: 23836809.
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    77. Bauer NS, Carroll AE, Downs SM. Understanding the acceptability of a computer decision support system in pediatric primary care. J Am Med Inform Assoc. 2014 Jan-Feb; 21(1):146-53. PMID: 23788628.
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    78. Anand V, Rosenman MB, Downs SM. Translating genome wide association study results to associations among common diseases: in silico study with an electronic medical record. Int J Med Inform. 2013 Sep; 82(9):864-74. PMID: 23743324.
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    79. Bauer NS, Gilbert AL, Carroll AE, Downs SM. Associations of early exposure to intimate partner violence and parental depression with subsequent mental health outcomes. JAMA Pediatr. 2013 Apr; 167(4):341-7. PMID: 23381234.
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    80. Ya R, Downs SM. Suppression of chemically induced and spontaneous mouse oocyte activation by AMP-activated protein kinase. Biol Reprod. 2013 Mar; 88(3):70. PMID: 23390161.
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    81. Thompson RT, Bennett WE, Finnell SM, Downs SM, Carroll AE. Increased length of stay and costs associated with weekend admissions for failure to thrive. Pediatrics. 2013 Mar; 131(3):e805-10. PMID: 23439903.
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    82. Anand V, Sheley ME, Xu S, Downs SM. Real time alert system: a disease management system leveraging health information exchange. Online J Public Health Inform. 2012; 4(3). PMID: 23569648.
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    83. Ya R, Downs SM. Perturbing microtubule integrity blocks AMP-activated protein kinase-induced meiotic resumption in cultured mouse oocytes. Zygote. 2014 Feb; 22(1):91-102. PMID: 23199370.
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    84. Downs S, Marquez J, Chiarelli P. Balance outcomes from two small rural hospitals. Aust J Rural Health. 2012 Oct; 20(5):275-80. PMID: 22998203.
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    85. Quadri-Sheriff M, Hendrix KS, Downs SM, Sturm LA, Zimet GD, Finnell SM. The role of herd immunity in parents' decision to vaccinate children: a systematic review. Pediatrics. 2012 Sep; 130(3):522-30. PMID: 22926181.
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    86. Carroll AE, Biondich P, Anand V, Dugan TM, Downs SM. A randomized controlled trial of screening for maternal depression with a clinical decision support system. J Am Med Inform Assoc. 2013 Mar-Apr; 20(2):311-6. PMID: 22744960.
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    87. Finnell SM, Carroll AE, Downs SM. The utility assessment method order influences measurement of parents' risk attitude. Value Health. 2012 Sep-Oct; 15(6):926-32. PMID: 22999143.
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    88. Bauer NS, Hus AM, Sullivan PD, Szczepaniak D, Carroll AE, Downs SM. A pilot study using children's books to understand caregiver perceptions of parenting practices. J Dev Behav Pediatr. 2012 Jun; 33(5):423-30. PMID: 22495054.
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    89. Zhu VJ, Grannis SJ, Tu W, Rosenman MB, Downs SM. Evaluation of a clinical decision support algorithm for patient-specific childhood immunization. Artif Intell Med. 2012 Sep; 56(1):51-7. PMID: 22633492.
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    90. Kemper AR, Downs SM. Making informed policy decisions about newborn hearing screening. Acad Pediatr. 2012 May-Jun; 12(3):157-8. PMID: 22583628.
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    91. Anand V, Carroll AE, Downs SM. Automated primary care screening in pediatric waiting rooms. Pediatrics. 2012 May; 129(5):e1275-81. PMID: 22508925.
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    92. Roberts KB, Finnell SM, Downs SM. Response to the AAP Section on Urology concerns about the AAP Urinary Tract Infection Guideline. Pediatrics. 2012 Apr; 129(4):e1054-6. PMID: 22412032.
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    93. Finnell SM, Downs SM, Roberts KB. An American response to the Italian guideline on urinary tract infections in young children. Acta Paediatr. 2012 May; 101(5):446-8. PMID: 22313350.
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    94. Laskey AL, Stump TE, Perkins SM, Zimet GD, Sherman SJ, Downs SM. Influence of race and socioeconomic status on the diagnosis of child abuse: a randomized study. J Pediatr. 2012 Jun; 160(6):1003-8.e1. PMID: 22221565.
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    95. Downs SM, Anand V, Sheley M, Grannis SJ. The Last Mile: Using Fax Machines to Exchange Data between Clinicians and Public Health. Online J Public Health Inform. 2011; 3(3). PMID: 23569620.
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    96. Finnell SM, Carroll AE, Downs SM. Application of classic utilities to published pediatric cost-utility studies. Acad Pediatr. 2012 May-Jun; 12(3):219-28. PMID: 22075466.
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    97. Downs SM. Mouse versus rat: Profound differences in meiotic regulation at the level of the isolated oocyte. Mol Reprod Dev. 2011 Oct-Nov; 78(10-11):778-94. PMID: 21953615.
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    98. Finnell SM, Carroll AE, Downs SM. Technical report—Diagnosis and management of an initial UTI in febrile infants and young children. Pediatrics. 2011 Sep; 128(3):e749-70. PMID: 21873694.
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    99. Saysana M, Downs SM. Piloting group well child visits in pediatric resident continuity clinic. Clin Pediatr (Phila). 2012 Feb; 51(2):134-9. PMID: 21868590.
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    100. Carroll AE, Biondich PG, Anand V, Dugan TM, Sheley ME, Xu SZ, Downs SM. Targeted screening for pediatric conditions with the CHICA system. J Am Med Inform Assoc. 2011 Jul-Aug; 18(4):485-90. PMID: 21672910.
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    101. Bauer NS, Sullivan PD, Hus AM, Downs SM. Promoting mental health competency in residency training. Patient Educ Couns. 2011 Dec; 85(3):e260-4. PMID: 21570796.
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    102. McHugh D, Cameron CA, Abdenur JE, Abdulrahman M, Adair O, Al Nuaimi SA, Åhlman H, Allen JJ, Antonozzi I, Archer S, Au S, Auray-Blais C, Baker M, Bamforth F, Beckmann K, Pino GB, Berberich SL, Binard R, Boemer F, Bonham J, Breen NN, Bryant SC, Caggana M, Caldwell SG, Camilot M, Campbell C, Carducci C, Bryant SC, Caggana M, Caldwell SG, Camilot M, Campbell C, Carducci C, Cariappa R, Carlisle C, Caruso U, Cassanello M, Castilla AM, Ramos DE, Chakraborty P, Chandrasekar R, Ramos AC, Cheillan D, Chien YH, Childs TA, Chrastina P, Sica YC, de Juan JA, Colandre ME, Espinoza VC, Corso G, Currier R, Cyr D, Czuczy N, D'Apolito O, Davis T, de Sain-Van der Velden MG, Delgado Pecellin C, Di Gangi IM, Di Stefano CM, Dotsikas Y, Downing M, Downs SM, Dy B, Dymerski M, Rueda I, Elvers B, Eaton R, Eckerd BM, El Mougy F, Eroh S, Espada M, Evans C, Fawbush S, Fijolek KF, Fisher L, Franzson L, Frazier DM, Garcia LR, Bermejo MS, Gavrilov D, Gerace R, Giordano G, Irazabal YG, Greed LC, Grier R, Grycki E, Gu X, Gulamali-Majid F, Hagar AF, Han L, Hannon WH, Haslip C, Hassan FA, He M, Hietala A, Himstedt L, Hoffman GL, Hoffman W, Hoggatt P, Hopkins PV, Hougaard DM, Hughes K, Hunt PR, Hwu WL, Hynes J, Ibarra-González I, Ingham CA, Ivanova M, Jacox WB, John C, Johnson JP, Jónsson JJ, Karg E, Kasper D, Klopper B, Katakouzinos D, Khneisser I, Knoll D, Kobayashi H, Koneski R, Kozich V, Kouapei R, Kohlmueller D, Kremensky I, la Marca G, Lavochkin M, Lee SY, Lehotay DC, Lemes A, Lepage J, Lesko B, Lewis B, Lim C, Linard S, Lindner M, Lloyd-Puryear MA, Lorey F, Loukas YL, Luedtke J, Maffitt N, Magee JF, Manning A, Manos S, Marie S, Hadachi SM, Marquardt G, Martin SJ, Matern D, Mayfield Gibson SK, Mayne P, McCallister TD, McCann M, McClure J, McGill JJ, McKeever CD, McNeilly B, Morrissey MA, Moutsatsou P, Mulcahy EA, Nikoloudis D, Norgaard-Pedersen B, Oglesbee D, Oltarzewski M, Ombrone D, Ojodu J, Papakonstantinou V, Reoyo SP, Park HD, Pasquali M, Pasquini E, Patel P, Pass KA, Peterson C, Pettersen RD, Pitt JJ, Poh S, Pollak A, Porter C, Poston PA, Price RW, Queijo C, Quesada J, Randell E, Ranieri E, Raymond K, Reddic JE, Reuben A, Ricciardi C, Rinaldo P, Rivera JD, Roberts A, Rocha H, Roche G, Greenberg CR, Mellado JM, Juan-Fita MJ, Ruiz C, Ruoppolo M, Rutledge SL, Ryu E, Saban C, Sahai I, García-Blanco MI, Santiago-Borrero P, Schenone A, Schoos R, Schweitzer B, Scott P, Seashore MR, Seeterlin MA, Sesser DE, Sevier DW, Shone SM, Sinclair G, Skrinska VA, Stanley EL, Strovel ET, Jones AL, Sunny S, Takats Z, Tanyalcin T, Teofoli F, Thompson JR, Tomashitis K, Domingos MT, Torres J, Torres R, Tortorelli S, Turi S, Turner K, Tzanakos N, Valiente AG, Vallance H, Vela-Amieva M, Vilarinho L, von Döbeln U, Vincent MF, Vorster BC, Watson MS, Webster D, Weiss S, Wilcken B, Wiley V, Williams SK, Willis SA, Woontner M, Wright K, Yahyaoui R, Yamaguchi S, Yssel M, Zakowicz WM. Clinical validation of cutoff target ranges in newborn screening of metabolic disorders by tandem mass spectrometry: a worldwide collaborative project. Genet Med. 2011 Mar; 13(3):230-54. PMID: 21325949.
      Citations:    
    103. Holmes AM, Ackermann RT, Katz BP, Downs SM, Inui TS. Case finding with incomplete administrative data: observations on playing with less than a full deck. Popul Health Manag. 2010 Dec; 13(6):325-30. PMID: 21091372.
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    104. Anand V, Downs SM. An Empirical Validation of Recursive Noisy OR (RNOR) Rule for Asthma Prediction. AMIA Annu Symp Proc. 2010 Nov 13; 2010:16-20. PMID: 21346932.
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    105. Downs SM, Anand V, Dugan TM, Carroll AE. You can lead a horse to water: physicians' responses to clinical reminders. AMIA Annu Symp Proc. 2010 Nov 13; 2010:167-71. PMID: 21346962.
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    106. Klann J, Schadow G, Downs SM. A method to compute treatment suggestions from local order entry data. AMIA Annu Symp Proc. 2010 Nov 13; 2010:387-91. PMID: 21347006.
      Citations:    
    107. Downs SM, Ya R, Davis CC. Role of AMPK throughout meiotic maturation in the mouse oocyte: evidence for promotion of polar body formation and suppression of premature activation. Mol Reprod Dev. 2010 Oct; 77(10):888-99. PMID: 20830737.
      Citations:    
    108. Brennan PF, Downs S, Casper G. Project HealthDesign: rethinking the power and potential of personal health records. J Biomed Inform. 2010 Oct; 43(5 Suppl):S3-S5. PMID: 20937482.
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    109. Downs SM. Regulation of the G2/M transition in rodent oocytes. Mol Reprod Dev. 2010 Jul; 77(7):566-85. PMID: 20578061.
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    110. Roth AM, Ackermann RT, Downs SM, Downs AM, Zillich AJ, Holmes AM, Katz BP, Murray MD, Inui TS. The structure and content of telephonic scripts found useful in a Medicaid Chronic Disease Management Program. Chronic Illn. 2010 Jun; 6(2):83-8. PMID: 20484324.
      Citations:    
    111. Downs SM, van Dyck PC, Rinaldo P, McDonald C, Howell RR, Zuckerman A, Downing G. Improving newborn screening laboratory test ordering and result reporting using health information exchange. J Am Med Inform Assoc. 2010 Jan-Feb; 17(1):13-8. PMID: 20064796.
      Citations:    
    112. Zhu VJ, Grannis SJ, Rosenman MB, Downs SM. Implementing broad scale childhood immunization decision support as a web service. AMIA Annu Symp Proc. 2009 Nov 14; 2009:745-9. PMID: 20351952.
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    113. Downs SM, Mosey JL, Klinger J. Fatty acid oxidation and meiotic resumption in mouse oocytes. Mol Reprod Dev. 2009 Sep; 76(9):844-53. PMID: 19455666.
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    114. Chen J, Chi MM, Moley KH, Downs SM. cAMP pulsing of denuded mouse oocytes increases meiotic resumption via activation of AMP-activated protein kinase. Reproduction. 2009 Nov; 138(5):759-70. PMID: 19700529.
      Citations:    
    115. Zhu VJ, Overhage MJ, Egg J, Downs SM, Grannis SJ. An empiric modification to the probabilistic record linkage algorithm using frequency-based weight scaling. J Am Med Inform Assoc. 2009 Sep-Oct; 16(5):738-45. PMID: 19567789.
      Citations:    
    116. Carroll AE, Downs SM. Improving decision analyses: parent preferences (utility values) for pediatric health outcomes. J Pediatr. 2009 Jul; 155(1):21-5, 25.e1-5. PMID: 19394030.
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    117. Finnell SM, Christenson JC, Downs SM. Latent tuberculosis infection in children: a call for revised treatment guidelines. Pediatrics. 2009 Mar; 123(3):816-22. PMID: 19255008.
      Citations:    
    118. Brennan PF, Casper G, Downs S, Aulahk V. Project HealthDesign: enhancing action through information. Stud Health Technol Inform. 2009; 146:214-8. PMID: 19592837.
      Citations:    
    119. Downs SM, Zhu V, Anand V, Biondich PG, Carroll AE. The CHICA smoking cessation system. AMIA Annu Symp Proc. 2008 Nov 06; 166-70. PMID: 18998823.
      Citations:    
    120. Anand V, Downs SM. Probabilistic asthma case finding: a noisy or reformulation. AMIA Annu Symp Proc. 2008 Nov 06; 6-10. PMID: 18998893.
      Citations:    
    121. Holmes AM, Ackermann RD, Zillich AJ, Katz BP, Downs SM, Inui TS. The net fiscal impact of a chronic disease management program: Indiana Medicaid. Health Aff (Millwood). 2008 May-Jun; 27(3):855-64. PMID: 18474980.
      Citations:    
    122. Downs SM, Chen J. EGF-like peptides mediate FSH-induced maturation of cumulus cell-enclosed mouse oocytes. Mol Reprod Dev. 2008 Jan; 75(1):105-14. PMID: 17549700.
      Citations:    
    123. Brennan PF, Downs S, Casper G, Kenron D. Project HealthDesign: stimulating the next generation of personal health records. AMIA Annu Symp Proc. 2007 Oct 11; 70-4. PMID: 18693800.
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    124. Chen J, Downs SM. AMP-activated protein kinase is involved in hormone-induced mouse oocyte meiotic maturation in vitro. Dev Biol. 2008 Jan 01; 313(1):47-57. PMID: 18048025.
      Citations:    
    125. Thackeray J, Stelzner S, Downs SM, Miller C. Screening for intimate partner violence: the impact of screener and screening environment on victim comfort. J Interpers Violence. 2007 Jun; 22(6):659-70. PMID: 17515428.
      Citations:    
    126. Carroll AE, Marrero DG, Downs SM. The HealthPia GlucoPack Diabetes phone: a usability study. Diabetes Technol Ther. 2007 Apr; 9(2):158-64. PMID: 17425441.
      Citations:    
    127. Carroll AE, Downs SM, Marrero DG. What adolescents with type I diabetes and their parents want from testing technology: a qualitative study. Comput Inform Nurs. 2007 Jan-Feb; 25(1):23-9. PMID: 17215672.
      Citations:    
    128. LaRosa C, Downs SM. Meiotic induction by heat stress in mouse oocytes: involvement of AMP-activated protein kinase and MAPK family members. Biol Reprod. 2007 Mar; 76(3):476-86. PMID: 17108331.
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    129. Vreeman RC, Madsen KA, Vreeman DJ, Carroll AE, Downs SM. Compliance with guidelines for ADHD: a pilot study of an evaluation tool. J Pediatr. 2006 Oct; 149(4):568-71. PMID: 17011336.
      Citations:    
    130. Downs SM, Chen J. Induction of meiotic maturation in mouse oocytes by adenosine analogs. Mol Reprod Dev. 2006 Sep; 73(9):1159-68. PMID: 16804878.
      Citations:    
    131. Swigonski NL, Kuhlenschmidt HL, Bull MJ, Corkins MR, Downs SM. Screening for celiac disease in asymptomatic children with Down syndrome: cost-effectiveness of preventing lymphoma. Pediatrics. 2006 Aug; 118(2):594-602. PMID: 16882812.
      Citations:    
    132. Carroll AE, Downs SM. Comprehensive cost-utility analysis of newborn screening strategies. Pediatrics. 2006 May; 117(5 Pt 2):S287-95. PMID: 16735255.
      Citations:    
    133. Madsen KA, Bennett JE, Downs SM. The role of parental preferences in the management of fever without source among 3- to 36-month-old children: a decision analysis. Pediatrics. 2006 Apr; 117(4):1067-76. PMID: 16585300.
      Citations:    
    134. Downs SM, Gilles R, Vanderhoef C, Humpherson PG, Leese HJ. Differential response of cumulus cell-enclosed and denuded mouse oocytes in a meiotic induction model system. Mol Reprod Dev. 2006 Mar; 73(3):379-89. PMID: 16362973.
      Citations:    
    135. Biondich PG, Downs SM, Carroll AE, Laskey AL, Liu GC, Rosenman M, Wang J, Swigonski NL. Shortcomings in infant iron deficiency screening methods. Pediatrics. 2006 Feb; 117(2):290-4. PMID: 16452345.
      Citations:    
    136. Quiñonez RB, Stearns SC, Talekar BS, Rozier RG, Downs SM. Simulating cost-effectiveness of fluoride varnish during well-child visits for Medicaid-enrolled children. Arch Pediatr Adolesc Med. 2006 Feb; 160(2):164-70. PMID: 16461872.
      Citations:    
    137. Chen J, Hudson E, Chi MM, Chang AS, Moley KH, Hardie DG, Downs SM. AMPK regulation of mouse oocyte meiotic resumption in vitro. Dev Biol. 2006 Mar 15; 291(2):227-38. PMID: 16443210.
      Citations:    
    138. Rosenman MB, Holmes AM, Ackermann RT, Murray MD, Doebbeling CC, Katz B, Li J, Zillich A, Prescott VM, Downs SM, Inui TS. The Indiana Chronic Disease Management Program. Milbank Q. 2006; 84(1):135-63. PMID: 16529571.
      Citations:    
    139. Biondich PG, Downs SM, Carroll AE, Shiffman RN, McDonald CJ. Collaboration between the medical informatics community and guideline authors: fostering HIT standard development that matters. AMIA Annu Symp Proc. 2006; 36-40. PMID: 17238298.
      Citations:    
    140. Downs SM, Biondich PG, Anand V, Zore M, Carroll AE. Using Arden Syntax and adaptive turnaround documents to evaluate clinical guidelines. AMIA Annu Symp Proc. 2006; 214-8. PMID: 17238334.
      Citations:    
    141. LaRosa C, Downs SM. Stress stimulates AMP-activated protein kinase and meiotic resumption in mouse oocytes. Biol Reprod. 2006 Mar; 74(3):585-92. PMID: 16280415.
      Citations:    
    142. Macri JM, Downs SM, Demark-Wahnefried W, Snyder DC, Lobach DF. A simple, flexible and scalable approach for generating tailored questionnaires and health education messages. Comput Inform Nurs. 2005 Nov-Dec; 23(6):316-21. PMID: 16292046.
      Citations:    
    143. Li J, Holmes AM, Rosenman MB, Katz BP, Downs SM, Murray MD, Ackermann RT, Inui TS. Indiana chronic disease management program risk stratification analysis. Med Care. 2005 Oct; 43(10):979-84. PMID: 16166867.
      Citations:    
    144. Ackermann RT, Rosenman MB, Downs SM, Holmes AM, Katz BP, Li J, Zillich AJ, Carney CP, Inui TS. Telephonic case-finding of major depression in a Medicaid chronic disease management program for diabetes and heart failure. Gen Hosp Psychiatry. 2005 Sep-Oct; 27(5):338-43. PMID: 16168794.
      Citations:    
    145. LaRosa C, Downs SM. MEK inhibitors block AICAR-induced maturation in mouse oocytes by a MAPK-independent mechanism. Mol Reprod Dev. 2005 Feb; 70(2):235-45. PMID: 15570612.
      Citations:    
    146. Quiñonez RB, Downs SM, Shugars D, Christensen J, Vann WF. Assessing cost-effectiveness of sealant placement in children. J Public Health Dent. 2005; 65(2):82-9. PMID: 15929545.
      Citations:    
    147. Biondich PG, Downs SM, Anand V, Carroll AE. Automating the recognition and prioritization of needed preventive services: early results from the CHICA system. AMIA Annu Symp Proc. 2005; 51-5. PMID: 16779000.
      Citations:    
    148. Downs SM, Carroll AE, Anand V, Biondich PG. Human and system errors, using adaptive turnaround documents to capture data in a busy practice. AMIA Annu Symp Proc. 2005; 211-5. PMID: 16779032.
      Citations:    
    149. Colton SA, Downs SM. Potential role for the sorbitol pathway in the meiotic dysfunction exhibited by oocytes from diabetic mice. J Exp Zool A Comp Exp Biol. 2004 May 01; 301(5):439-48. PMID: 15114651.
      Citations:    
    150. Anand V, Biondich PG, Liu G, Rosenman M, Downs SM. Child Health Improvement through Computer Automation: the CHICA system. Stud Health Technol Inform. 2004; 107(Pt 1):187-91. PMID: 15360800.
      Citations:    
    151. Rosen AB, Tsai JS, Downs SM. Variations in risk attitude across race, gender, and education. Med Decis Making. 2003 Nov-Dec; 23(6):511-7. PMID: 14672111.
      Citations:    
    152. Lewis CL, Pignone MP, Sheridan SL, Downs SM, Kinsinger LS. A randomized trial of three videos that differ in the framing of information about mammography in women 40 to 49 years old. J Gen Intern Med. 2003 Nov; 18(11):875-83. PMID: 14687272.
      Citations:    
    153. Downs SM, Verhoeven A. Glutamine and the maintenance of meiotic arrest in mouse oocytes: influence of culture medium, glucose, and cumulus cells. Mol Reprod Dev. 2003 Sep; 66(1):90-7. PMID: 12874804.
      Citations:    
    154. Rosenman MB, Mahon BE, Downs SM, Kleiman MB. Oral erythromycin prophylaxis vs watchful waiting in caring for newborns exposed to Chlamydia trachomatis. Arch Pediatr Adolesc Med. 2003 Jun; 157(6):565-71. PMID: 12796237.
      Citations:    
    155. Colton SA, Humpherson PG, Leese HJ, Downs SM. Physiological changes in oocyte-cumulus cell complexes from diabetic mice that potentially influence meiotic regulation. Biol Reprod. 2003 Sep; 69(3):761-70. PMID: 12724281.
      Citations:    
    156. Biondich PG, Anand V, Downs SM, McDonald CJ. Using adaptive turnaround documents to electronically acquire structured data in clinical settings. AMIA Annu Symp Proc. 2003; 86-90. PMID: 14728139.
      Citations:    
    157. Colton SA, Pieper GM, Downs SM. Altered meiotic regulation in oocytes from diabetic mice. Biol Reprod. 2002 Jul; 67(1):220-31. PMID: 12080021.
      Citations:    
    158. Downs SM, Humpherson PG, Leese HJ. Pyruvate utilization by mouse oocytes is influenced by meiotic status and the cumulus oophorus. Mol Reprod Dev. 2002 May; 62(1):113-23. PMID: 11933168.
      Citations:    
    159. Downs SM, Hudson ER, Hardie DG. A potential role for AMP-activated protein kinase in meiotic induction in mouse oocytes. Dev Biol. 2002 May 01; 245(1):200-12. PMID: 11969266.
      Citations:    
    160. Bailit JL, Downs SM, Thorp JM. Reducing the caesarean delivery risk in elective inductions of labour: a decision analysis. Paediatr Perinat Epidemiol. 2002 Jan; 16(1):90-96. PMID: 11862951.
      Citations:    
    161. Biondich PG, Overhage JM, Dexter PR, Downs SM, Lemmon L, McDonald CJ. A modern optical character recognition system in a real world clinical setting: some accuracy and feasibility observations. Proc AMIA Symp. 2002; 56-60. PMID: 12463786.
      Citations:    
    162. Downs SM, Uner H. Expected value prioritization of prompts and reminders. Proc AMIA Symp. 2002; 215-9. PMID: 12463818.
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    163. Liu GC, Cunningham C, Downs SM, Marrero DG, Fineberg N. A spatial analysis of obesogenic environments for children. Proc AMIA Symp. 2002; 459-63. PMID: 12463866.
      Citations:    
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