Loading...
Header Logo
Keywords
Last Name

Timothy David Howard, Ph.D.

TitleProfessor
InstitutionWake Forest School of Medicine
DepartmentBiochemistry
Address
vCardDownload vCard
    Other Positions
    TitleAssociate Professor
    InstitutionWake Forest School of Medicine
    DepartmentPediatrics - Medical Genetics


    Collapse Research 
    Collapse research activities and funding
    R03ES015803     (HOWARD, TIMOTHY D)Sep 1, 2007 - Aug 31, 2009
    NIH/NIEHS
    Genetic analysis of organophosphate metabolism in NC farmworkers
    Role: Principal Investigator

    R21NS055999     (HOWARD, TIMOTHY D)Sep 15, 2007 - Jul 31, 2009
    NIH/NINDS
    Genetic evaluation of nitric oxide regulating genes in ischemic stroke
    Role: Principal Investigator

    U54DA049113     (OLIVIER, MICHAEL)Sep 1, 2019 - Jul 31, 2023
    NIH/NIDA
    Integrated Omics Analysis of Pain: Omics Data Generation Center
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Michalson KT, Macintyre AN, Sempowski GD, Bourland JD, Howard TD, Hawkins GA, Dugan GO, Cline JM, Register TC. Monocyte Polarization is Altered by Total-Body Irradiation in Male Rhesus Macaques: Implications for Delayed Effects of Acute Radiation Exposure. Radiat Res. 2019 Aug; 192(2):121-134. PMID: 31161966.
      View in: PubMed
    2. Vidrascu EM, Bashore AC, Howard TD, Moore JB. Effects of early- and mid-life stress on DNA methylation of genes associated with subclinical cardiovascular disease and cognitive impairment: a systematic review. BMC Med Genet. 2019 03 12; 20(1):39. PMID: 30866842.
      View in: PubMed
    3. Michalson KT, Groban L, Howard TD, Shively CA, Sophonsritsuk A, Appt SE, Cline JM, Clarkson TB, Carr JJ, Kitzman DW, Register TC. Estradiol Treatment Initiated Early After Ovariectomy Regulates Myocardial Gene Expression and Inhibits Diastolic Dysfunction in Female Cynomolgus Monkeys: Potential Roles for Calcium Homeostasis and Extracellular Matrix Remodeling. J Am Heart Assoc. 2018 Nov 06; 7(21):e009769. PMID: 30571375.
      View in: PubMed
    4. Chmielewski JP, Bowlby SC, Wheeler FB, Shi L, Sui G, Davis AL, Howard TD, D'Agostino RB, Miller LD, Sirintrapun SJ, Cramer SD, Kridel SJ. CD38 Inhibits Prostate Cancer Metabolism and Proliferation by Reducing Cellular NAD+ Pools. Mol Cancer Res. 2018 11; 16(11):1687-1700. PMID: 30076241.
      View in: PubMed
    5. Herrington DM, Mao C, Parker SJ, Fu Z, Yu G, Chen L, Venkatraman V, Fu Y, Wang Y, Howard TD, Jun G, Zhao CF, Liu Y, Saylor G, Spivia WR, Athas GB, Troxclair D, Hixson JE, Vander Heide RS, Wang Y, Van Eyk JE. Proteomic Architecture of Human Coronary and Aortic Atherosclerosis. Circulation. 2018 06 19; 137(25):2741-2756. PMID: 29915101.
      View in: PubMed
    6. Rahbar E, Waits CMK, Kirby EH, Miller LR, Ainsworth HC, Cui T, Sergeant S, Howard TD, Langefeld CD, Chilton FH. Allele-specific methylation in the FADS genomic region in DNA from human saliva, CD4+ cells, and total leukocytes. Clin Epigenetics. 2018; 10:46. PMID: 29636834.
      View in: PubMed
    7. Reynolds LM, Howard TD, Ruczinski I, Kanchan K, Seeds MC, Mathias RA, Chilton FH. Tissue-specific impact of FADS cluster variants on FADS1 and FADS2 gene expression. PLoS One. 2018; 13(3):e0194610. PMID: 29590160.
      View in: PubMed
    8. Arcury TA, Laurienti PJ, Talton JW, Chen H, Howard TD, Barr DB, Mora DC, Quandt SA. Pesticide Urinary Metabolites Among Latina Farmworkers and Nonfarmworkers in North Carolina. J Occup Environ Med. 2018 01; 60(1):e63-e71. PMID: 29023343.
      View in: PubMed
    9. McIntosh LA, Marion MC, Sudman M, Comeau ME, Becker ML, Bohnsack JF, Fingerlin TE, Griffin TA, Haas JP, Lovell DJ, Maier LA, Nigrovic PA, Prahalad S, Punaro M, Rosé CD, Wallace CA, Wise CA, Moncrieffe H, Howard TD, Langefeld CD, Thompson SD. Genome-Wide Association Meta-Analysis Reveals Novel Juvenile Idiopathic Arthritis Susceptibility Loci. Arthritis Rheumatol. 2017 11; 69(11):2222-2232. PMID: 28719732.
      View in: PubMed
    10. Rahbar E, Ainsworth HC, Howard TD, Hawkins GA, Ruczinski I, Mathias R, Seeds MC, Sergeant S, Hixson JE, Herrington DM, Langefeld CD, Chilton FH. Uncovering the DNA methylation landscape in key regulatory regions within the FADS cluster. PLoS One. 2017; 12(9):e0180903. PMID: 28957329.
      View in: PubMed
    11. Langefeld CD, Ainsworth HC, Cunninghame Graham DS, Kelly JA, Comeau ME, Marion MC, Howard TD, Ramos PS, Croker JA, Morris DL, Sandling JK, Almlöf JC, Acevedo-Vásquez EM, Alarcón GS, Babini AM, Baca V, Bengtsson AA, Berbotto GA, Bijl M, Brown EE, Brunner HI, Cardiel MH, Catoggio L, Cervera R, Cucho-Venegas JM, Dahlqvist SR, D'Alfonso S, Da Silva BM, de la Rúa Figueroa I, Doria A, Edberg JC, Endreffy E, Esquivel-Valerio JA, Fortin PR, Freedman BI, Frostegård J, García MA, de la Torre IG, Gilkeson GS, Gladman DD, Gunnarsson I, Guthridge JM, Huggins JL, James JA, Kallenberg CGM, Kamen DL, Karp DR, Kaufman KM, Kottyan LC, Kovács L, Laustrup H, Lauwerys BR, Li QZ, Maradiaga-Ceceña MA, Martín J, McCune JM, McWilliams DR, Merrill JT, Miranda P, Moctezuma JF, Nath SK, Niewold TB, Orozco L, Ortego-Centeno N, Petri M, Pineau CA, Pons-Estel BA, Pope J, Raj P, Ramsey-Goldman R, Reveille JD, Russell LP, Sabio JM, Aguilar-Salinas CA, Scherbarth HR, Scorza R, Seldin MF, Sjöwall C, Svenungsson E, Thompson SD, Toloza SMA, Truedsson L, Tusié-Luna T, Vasconcelos C, Vilá LM, Wallace DJ, Weisman MH, Wither JE, Bhangale T, Oksenberg JR, Rioux JD, Gregersen PK, Syvänen AC, Rönnblom L, Criswell LA, Jacob CO, Sivils KL, Tsao BP, Schanberg LE, Behrens TW, Silverman ED, Alarcón-Riquelme ME, Kimberly RP, Harley JB, Wakeland EK, Graham RR, Gaffney PM, Vyse TJ. Transancestral mapping and genetic load in systemic lupus erythematosus. Nat Commun. 2017 07 17; 8:16021. PMID: 28714469.
      View in: PubMed
    12. Arcury TA, Chen H, Laurienti PJ, Howard TD, Barr DB, Mora DC, Quandt SA. Farmworker and nonfarmworker Latino immigrant men in North Carolina have high levels of specific pesticide urinary metabolites. Arch Environ Occup Health. 2018 07 04; 73(4):219-227. PMID: 28622109.
      View in: PubMed
    13. Hixson JE, Jun G, Shimmin LC, Wang Y, Yu G, Mao C, Warren AS, Howard TD, Heide RSV, Van Eyk J, Wang Y, Herrington DM. Whole Exome Sequencing to Identify Genetic Variants Associated with Raised Atherosclerotic Lesions in Young Persons. Sci Rep. 2017 06 22; 7(1):4091. PMID: 28642624.
      View in: PubMed
    14. Bahrami M, Laurienti PJ, Quandt SA, Talton J, Pope CN, Summers P, Burdette JH, Chen H, Liu J, Howard TD, Arcury TA, Simpson SL. The impacts of pesticide and nicotine exposures on functional brain networks in Latino immigrant workers. Neurotoxicology. 2017 Sep; 62:138-150. PMID: 28583619.
      View in: PubMed
    15. Mao C, Howard TD, Sullivan D, Fu Z, Yu G, Parker SJ, Will R, Vander Heide RS, Wang Y, Hixson J, Van Eyk J, Herrington DM. Bioinformatic Analysis of Coronary Disease Associated SNPs and Genes to Identify Proteins Potentially Involved in the Pathogenesis of Atherosclerosis. J Proteom Genom Res. 2017; 2(1):1-12. PMID: 29367937.
      View in: PubMed
    16. Sandberg JC, Rodriguez G, Howard TD, Quandt SA, Arcury TA. "He Beat You in the Blood": Knowledge and Beliefs About the Transmission of Traits Among Latinos from Mexico and Central America. J Immigr Minor Health. 2017 02; 19(1):170-178. PMID: 26660317.
      View in: PubMed
    17. Arcury TA, Laurienti PJ, Chen H, Howard TD, Barr DB, Mora DC, Summers P, Quandt SA. Organophosphate Pesticide Urinary Metabolites Among Latino Immigrants: North Carolina Farmworkers and Non-farmworkers Compared. J Occup Environ Med. 2016 11; 58(11):1079-1086. PMID: 27820757.
      View in: PubMed
    18. Howard TD, Hsu FC, Chen H, Quandt SA, Talton JW, Summers P, Arcury TA. Changes in DNA methylation over the growing season differ between North Carolina farmworkers and non-farmworkers. Int Arch Occup Environ Health. 2016 Oct; 89(7):1103-10. PMID: 27349971.
      View in: PubMed
    19. Cui T, Hester AG, Seeds MC, Rahbar E, Howard TD, Sergeant S, Chilton FH. Impact of Genetic and Epigenetic Variations Within the FADS Cluster on the Composition and Metabolism of Polyunsaturated Fatty Acids in Prostate Cancer. Prostate. 2016 09; 76(13):1182-91. PMID: 27197070.
      View in: PubMed
    20. Laurienti PJ, Burdette JH, Talton J, Pope CN, Summers P, Walker FO, Quandt SA, Lyday RG, Chen H, Howard TD, Arcury TA. Brain Anatomy in Latino Farmworkers Exposed to Pesticides and Nicotine. J Occup Environ Med. 2016 05; 58(5):436-43. PMID: 27158949.
      View in: PubMed
    21. Alarcón-Riquelme ME, Ziegler JT, Molineros J, Howard TD, Moreno-Estrada A, Sánchez-Rodríguez E, Ainsworth HC, Ortiz-Tello P, Comeau ME, Rasmussen A, Kelly JA, Adler A, Acevedo-Vázquez EM, Cucho-Venegas JM, García-De la Torre I, Cardiel MH, Miranda P, Catoggio LJ, Maradiaga-Ceceña M, Gaffney PM, Vyse TJ, Criswell LA, Tsao BP, Sivils KL, Bae SC, James JA, Kimberly RP, Kaufman KM, Harley JB, Esquivel-Valerio JA, Moctezuma JF, García MA, Berbotto GA, Babini AM, Scherbarth H, Toloza S, Baca V, Nath SK, Aguilar Salinas C, Orozco L, Tusié-Luna T, Zidovetzki R, Pons-Estel BA, Langefeld CD, Jacob CO. Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture. Arthritis Rheumatol. 2016 Apr; 68(4):932-43. PMID: 26606652.
      View in: PubMed
    22. Dewi FN, Wood CE, Willson CJ, Register TC, Lees CJ, Howard TD, Huang Z, Murphy SK, Tooze JA, Chou JW, Miller LD, Cline JM. Effects of Pubertal Exposure to Dietary Soy on Estrogen Receptor Activity in the Breast of Cynomolgus Macaques. Cancer Prev Res (Phila). 2016 05; 9(5):385-95. PMID: 27006379.
      View in: PubMed
    23. Ohar JA, Cheung M, Talarchek J, Howard SE, Howard TD, Hesdorffer M, Peng H, Rauscher FJ, Testa JR. Germline BAP1 Mutational Landscape of Asbestos-Exposed Malignant Mesothelioma Patients with Family History of Cancer. Cancer Res. 2016 Jan 15; 76(2):206-15. PMID: 26719535.
      View in: PubMed
    24. Arcury TA, Laurienti PJ, Talton JW, Chen H, Howard TD, Summers P, Quandt SA. Urinary Cotinine Levels Among Latino Tobacco Farmworkers in North Carolina Compared to Latinos Not Employed in Agriculture. Nicotine Tob Res. 2016 06; 18(6):1517-25. PMID: 26377519.
      View in: PubMed
    25. Reynolds LM, Wan M, Ding J, Taylor JR, Lohman K, Su D, Bennett BD, Porter DK, Gimple R, Pittman GS, Wang X, Howard TD, Siscovick D, Psaty BM, Shea S, Burke GL, Jacobs DR, Rich SS, Hixson JE, Stein JH, Stunnenberg H, Barr RG, Kaufman JD, Post WS, Hoeschele I, Herrington DM, Bell DA, Liu Y. DNA Methylation of the Aryl Hydrocarbon Receptor Repressor Associations With Cigarette Smoking and Subclinical Atherosclerosis. Circ Cardiovasc Genet. 2015 Oct; 8(5):707-16. PMID: 26307030.
      View in: PubMed
    26. Ding J, Reynolds LM, Zeller T, Müller C, Lohman K, Nicklas BJ, Kritchevsky SB, Huang Z, de la Fuente A, Soranzo N, Settlage RE, Chuang CC, Howard T, Xu N, Goodarzi MO, Chen YD, Rotter JI, Siscovick DS, Parks JS, Murphy S, Jacobs DR, Post W, Tracy RP, Wild PS, Blankenberg S, Hoeschele I, Herrington D, McCall CE, Liu Y. Alterations of a Cellular Cholesterol Metabolism Network Are a Molecular Feature of Obesity-Related Type 2 Diabetes and Cardiovascular Disease. Diabetes. 2015 Oct; 64(10):3464-74. PMID: 26153245.
      View in: PubMed
    27. Nguyen HT, Quandt SA, Summers P, Morgan TM, Chen H, Walker FO, Howard TD, Galván L, Arcury TA. Learning Ability as a Function of Practice: Does It Apply to Farmworkers? J Occup Environ Med. 2015 Jun; 57(6):676-81. PMID: 25738949.
      View in: PubMed
    28. Shashi V, Xie P, Schoch K, Goldstein DB, Howard TD, Berry MN, Schwartz CE, Cronin K, Sliwa S, Allen A, Need AC. The RBMX gene as a candidate for the Shashi X-linked intellectual disability syndrome. Clin Genet. 2015 Oct; 88(4):386-90. PMID: 25256757.
      View in: PubMed
    29. Hester AG, Murphy RC, Uhlson CJ, Ivester P, Lee TC, Sergeant S, Miller LR, Howard TD, Mathias RA, Chilton FH. Relationship between a common variant in the fatty acid desaturase (FADS) cluster and eicosanoid generation in humans. J Biol Chem. 2014 Aug 08; 289(32):22482-9. PMID: 24962583.
      View in: PubMed
    30. Howard TD, Mathias RA, Seeds MC, Herrington DM, Hixson JE, Shimmin LC, Hawkins GA, Sellers M, Ainsworth HC, Sergeant S, Miller LR, Chilton FH. DNA methylation in an enhancer region of the FADS cluster is associated with FADS activity in human liver. PLoS One. 2014; 9(5):e97510. PMID: 24842322.
      View in: PubMed
    31. Arcury TA, Nguyen HT, Summers P, Talton JW, Holbrook LC, Walker FO, Chen H, Howard TD, Galván L, Quandt SA. Lifetime and current pesticide exposure among Latino farmworkers in comparison to other Latino immigrants. Am J Ind Med. 2014 Jul; 57(7):776-87. PMID: 24737498.
      View in: PubMed
    32. Woo D, Falcone GJ, Devan WJ, Brown WM, Biffi A, Howard TD, Anderson CD, Brouwers HB, Valant V, Battey TW, Radmanesh F, Raffeld MR, Baedorf-Kassis S, Deka R, Woo JG, Martin LJ, Haverbusch M, Moomaw CJ, Sun G, Broderick JP, Flaherty ML, Martini SR, Kleindorfer DO, Kissela B, Comeau ME, Jagiella JM, Schmidt H, Freudenberger P, Pichler A, Enzinger C, Hansen BM, Norrving B, Jimenez-Conde J, Giralt-Steinhauer E, Elosua R, Cuadrado-Godia E, Soriano C, Roquer J, Kraft P, Ayres AM, Schwab K, McCauley JL, Pera J, Urbanik A, Rost NS, Goldstein JN, Viswanathan A, Stögerer EM, Tirschwell DL, Selim M, Brown DL, Silliman SL, Worrall BB, Meschia JF, Kidwell CS, Montaner J, Fernandez-Cadenas I, Delgado P, Malik R, Dichgans M, Greenberg SM, Rothwell PM, Lindgren A, Slowik A, Schmidt R, Langefeld CD, Rosand J. Meta-analysis of genome-wide association studies identifies 1q22 as a susceptibility locus for intracerebral hemorrhage. Am J Hum Genet. 2014 Apr 03; 94(4):511-21. PMID: 24656865.
      View in: PubMed
    33. Spears CR, Sandberg JC, O'Neill JL, Grzywacz JG, Howard TD, Feldman SR, Arcury TA. Recruiting underserved mothers to medical research: findings from North Carolina. J Health Care Poor Underserved. 2013 Nov; 24(4):1801-15. PMID: 24185171.
      View in: PubMed
    34. Bailey JN, Lu L, Chou JW, Xu J, McWilliams DR, Howard TD, Freedman BI, Bowden DW, Langefeld CD, Palmer ND. The Role of Copy Number Variation in African Americans with Type 2 Diabetes-Associated End Stage Renal Disease. J Mol Genet Med. 2013 Jul 31; 7:61. PMID: 24707315.
      View in: PubMed
    35. Liu Y, Ding J, Reynolds LM, Lohman K, Register TC, De La Fuente A, Howard TD, Hawkins GA, Cui W, Morris J, Smith SG, Barr RG, Kaufman JD, Burke GL, Post W, Shea S, McCall CE, Siscovick D, Jacobs DR, Tracy RP, Herrington DM, Hoeschele I. Methylomics of gene expression in human monocytes. Hum Mol Genet. 2013 Dec 15; 22(24):5065-74. PMID: 23900078.
      View in: PubMed
    36. Monda KL, Chen GK, Taylor KC, Palmer C, Edwards TL, Lange LA, Ng MC, Adeyemo AA, Allison MA, Bielak LF, Chen G, Graff M, Irvin MR, Rhie SK, Li G, Liu Y, Liu Y, Lu Y, Nalls MA, Sun YV, Wojczynski MK, Yanek LR, Aldrich MC, Ademola A, Amos CI, Bandera EV, Bock CH, Britton A, Broeckel U, Cai Q, Caporaso NE, Carlson CS, Carpten J, Casey G, Chen WM, Chen F, Chen YD, Chiang CW, Coetzee GA, Demerath E, Deming-Halverson SL, Driver RW, Dubbert P, Feitosa MF, Feng Y, Freedman BI, Gillanders EM, Gottesman O, Guo X, Haritunians T, Harris T, Harris CC, Hennis AJ, Hernandez DG, McNeill LH, Howard TD, Howard BV, Howard VJ, Johnson KC, Kang SJ, Keating BJ, Kolb S, Kuller LH, Kutlar A, Langefeld CD, Lettre G, Lohman K, Lotay V, Lyon H, Manson JE, Maixner W, Meng YA, Monroe KR, Morhason-Bello I, Murphy AB, Mychaleckyj JC, Nadukuru R, Nathanson KL, Nayak U, N'diaye A, Nemesure B, Wu SY, Leske MC, Neslund-Dudas C, Neuhouser M, Nyante S, Ochs-Balcom H, Ogunniyi A, Ogundiran TO, Ojengbede O, Olopade OI, Palmer JR, Ruiz-Narvaez EA, Palmer ND, Press MF, Rampersaud E, Rasmussen-Torvik LJ, Rodriguez-Gil JL, Salako B, Schadt EE, Schwartz AG, Shriner DA, Siscovick D, Smith SB, Wassertheil-Smoller S, Speliotes EK, Spitz MR, Sucheston L, Taylor H, Tayo BO, Tucker MA, Van Den Berg DJ, Edwards DR, Wang Z, Wiencke JK, Winkler TW, Witte JS, Wrensch M, Wu X, Yang JJ, Levin AM, Young TR, Zakai NA, Cushman M, Zanetti KA, Zhao JH, Zhao W, Zheng Y, Zhou J, Ziegler RG, Zmuda JM, Fernandes JK, Gilkeson GS, Kamen DL, Hunt KJ, Spruill IJ, Ambrosone CB, Ambs S, Arnett DK, Atwood L, Becker DM, Berndt SI, Bernstein L, Blot WJ, Borecki IB, Bottinger EP, Bowden DW, Burke G, Chanock SJ, Cooper RS, Ding J, Duggan D, Evans MK, Fox C, Garvey WT, Bradfield JP, Hakonarson H, Grant SF, Hsing A, Chu L, Hu JJ, Huo D, Ingles SA, John EM, Jordan JM, Kabagambe EK, Kardia SL, Kittles RA, Goodman PJ, Klein EA, Kolonel LN, Le Marchand L, Liu S, McKnight B, Millikan RC, Mosley TH, Padhukasahasram B, Williams LK, Patel SR, Peters U, Pettaway CA, Peyser PA, Psaty BM, Redline S, Rotimi CN, Rybicki BA, Sale MM, Schreiner PJ, Signorello LB, Singleton AB, Stanford JL, Strom SS, Thun MJ, Vitolins M, Zheng W, Moore JH, Williams SM, Ketkar S, Zhu X, Zonderman AB, Kooperberg C, Papanicolaou GJ, Henderson BE, Reiner AP, Hirschhorn JN, Loos RJ, North KE, Haiman CA. A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet. 2013 Jun; 45(6):690-6. PMID: 23583978.
      View in: PubMed
    37. Fu Z, Yan K, Rosenberg A, Jin Z, Crain B, Athas G, Heide RS, Howard T, Everett AD, Herrington D, Van Eyk JE. Improved protein extraction and protein identification from archival formalin-fixed paraffin-embedded human aortas. Proteomics Clin Appl. 2013 Apr; 7(3-4):217-24. PMID: 23339088.
      View in: PubMed
    38. Li X, Hawkins GA, Ampleford EJ, Moore WC, Li H, Hastie AT, Howard TD, Boushey HA, Busse WW, Calhoun WJ, Castro M, Erzurum SC, Israel E, Lemanske RF, Szefler SJ, Wasserman SI, Wenzel SE, Peters SP, Meyers DA, Bleecker ER. Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients. J Allergy Clin Immunol. 2013 Aug; 132(2):313-20.e15. PMID: 23541324.
      View in: PubMed
    39. Quandt SA, Kucera KL, Haynes C, Klein BG, Langley R, Agnew M, Levin JL, Howard T, Nussbaum MA. Occupational health outcomes for workers in the agriculture, forestry and fishing sector: implications for immigrant workers in the southeastern US. Am J Ind Med. 2013 Aug; 56(8):940-59. PMID: 23450720.
      View in: PubMed
    40. Shah SA, Herrington DM, Howard TD, Divers J, Arnett DK, Burke GL, Kao WH, Guo X, Siscovick DS, Chakravarti A, Lima JA, Psaty BM, Tomaselli GF, Rich SS, Bowden DW, Post W. Associations between NOS1AP single nucleotide polymorphisms (SNPs) and QT interval duration in four racial/ethnic groups in the Multi-Ethnic Study of Atherosclerosis (MESA). Ann Noninvasive Electrocardiol. 2013 Jan; 18(1):29-40. PMID: 23347024.
      View in: PubMed
    41. Woo JG, Martin LJ, Ding L, Brown WM, Howard TD, Langefeld CD, Moomaw CJ, Haverbusch M, Sun G, Indugula SR, Cheng H, Deka R, Woo D. Quantitative criteria for improving performance of buccal DNA for high-throughput genetic analysis. BMC Genet. 2012 Aug 25; 13:75. PMID: 22920755.
      View in: PubMed
    42. Thompson SD, Marion MC, Sudman M, Ryan M, Tsoras M, Howard TD, Barnes MG, Ramos PS, Thomson W, Hinks A, Haas JP, Prahalad S, Bohnsack JF, Wise CA, Punaro M, Rosé CD, Pajewski NM, Spigarelli M, Keddache M, Wagner M, Langefeld CD, Glass DN. Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13. Arthritis Rheum. 2012 Aug; 64(8):2781-91. PMID: 22354554.
      View in: PubMed
    43. Shashi V, Francis A, Hooper SR, Kranz PG, Zapadka M, Schoch K, Ip E, Tandon N, Howard TD, Keshavan MS. Increased corpus callosum volume in children with chromosome 22q11.2 deletion syndrome is associated with neurocognitive deficits and genetic polymorphisms. Eur J Hum Genet. 2012 Oct; 20(10):1051-7. PMID: 22763378.
      View in: PubMed
    44. Li X, Ampleford EJ, Howard TD, Moore WC, Torgerson DG, Li H, Busse WW, Castro M, Erzurum SC, Israel E, Nicolae DL, Ober C, Wenzel SE, Hawkins GA, Bleecker ER, Meyers DA. Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases. J Allergy Clin Immunol. 2012 Oct; 130(4):861-8.e7. PMID: 22694930.
      View in: PubMed
    45. Torgerson DG, Capurso D, Ampleford EJ, Li X, Moore WC, Gignoux CR, Hu D, Eng C, Mathias RA, Busse WW, Castro M, Erzurum SC, Fitzpatrick AM, Gaston B, Israel E, Jarjour NN, Teague WG, Wenzel SE, Rodríguez-Santana JR, Rodríguez-Cintrón W, Avila PC, Ford JG, Barnes KC, Burchard EG, Howard TD, Bleecker ER, Meyers DA, Cox NJ, Ober C, Nicolae DL. Genome-wide ancestry association testing identifies a common European variant on 6q14.1 as a risk factor for asthma in African American subjects. J Allergy Clin Immunol. 2012 Sep; 130(3):622-629.e9. PMID: 22607992.
      View in: PubMed
    46. Hawkins GA, Robinson MB, Hastie AT, Li X, Li H, Moore WC, Howard TD, Busse WW, Erzurum SC, Wenzel SE, Peters SP, Meyers DA, Bleecker ER. The IL6R variation Asp(358)Ala is a potential modifier of lung function in subjects with asthma. J Allergy Clin Immunol. 2012 Aug; 130(2):510-5.e1. PMID: 22554704.
      View in: PubMed
    47. Das Chakraborty R, Chakraborty D, Bernal AJ, Schoch K, Howard TD, Ip EH, Hooper SR, Keshavan MS, Jirtle RL, Shashi V. Dysregulation of DGCR6 and DGCR6L: psychopathological outcomes in chromosome 22q11.2 deletion syndrome. Transl Psychiatry. 2012 Apr 24; 2:e105. PMID: 22832905.
      View in: PubMed
    48. O'Donnell CJ, Kavousi M, Smith AV, Kardia SL, Feitosa MF, Hwang SJ, Sun YV, Province MA, Aspelund T, Dehghan A, Hoffmann U, Bielak LF, Zhang Q, Eiriksdottir G, van Duijn CM, Fox CS, de Andrade M, Kraja AT, Sigurdsson S, Elias-Smale SE, Murabito JM, Launer LJ, van der Lugt A, Kathiresan S, Krestin GP, Herrington DM, Howard TD, Liu Y, Post W, Mitchell BD, O'Connell JR, Shen H, Shuldiner AR, Altshuler D, Elosua R, Salomaa V, Schwartz SM, Siscovick DS, Voight BF, Bis JC, Glazer NL, Psaty BM, Boerwinkle E, Heiss G, Blankenberg S, Zeller T, Wild PS, Schnabel RB, Schillert A, Ziegler A, Münzel TF, White CC, Rotter JI, Nalls M, Oudkerk M, Johnson AD, Newman AB, Uitterlinden AG, Massaro JM, Cunningham J, Harris TB, Hofman A, Peyser PA, Borecki IB, Cupples LA, Gudnason V, Witteman JC. Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction. Circulation. 2011 Dec 20; 124(25):2855-64. PMID: 22144573.
      View in: PubMed
    49. Mitchell GF, Verwoert GC, Tarasov KV, Isaacs A, Smith AV, Rietzschel ER, Tanaka T, Liu Y, Parsa A, Najjar SS, O'Shaughnessy KM, Sigurdsson S, De Buyzere ML, Larson MG, Sie MP, Andrews JS, Post WS, Mattace-Raso FU, McEniery CM, Eiriksdottir G, Segers P, Vasan RS, van Rijn MJ, Howard TD, McArdle PF, Dehghan A, Jewell ES, Newhouse SJ, Bekaert S, Hamburg NM, Newman AB, Hofman A, Scuteri A, De Bacquer D, Ikram MA, Psaty BM, Fuchsberger C, Olden M, Wain LV, Elliott P, Smith NL, Felix JF, Erdmann J, Vita JA, Sutton-Tyrrell K, Sijbrands EJ, Sanna S, Launer LJ, De Meyer T, Johnson AD, Schut AF, Herrington DM, Rivadeneira F, Uda M, Wilkinson IB, Aspelund T, Gillebert TC, Van Bortel L, Benjamin EJ, Oostra BA, Ding J, Gibson Q, Uitterlinden AG, Abecasis GR, Cockcroft JR, Gudnason V, De Backer GG, Ferrucci L, Harris TB, Shuldiner AR, van Duijn CM, Levy D, Lakatta EG, Witteman JC. Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium. Circ Cardiovasc Genet. 2012 Feb 01; 5(1):81-90. PMID: 22068335.
      View in: PubMed
    50. Li X, Ampleford EJ, Howard TD, Moore WC, Li H, Busse WW, Castro M, Erzurum SC, Fitzpatrick AM, Gaston B, Israel E, Jarjour NN, Teague WG, Wenzel SE, Hawkins GA, Bleecker ER, Meyers DA. The C11orf30-LRRC32 region is associated with total serum IgE levels in asthmatic patients. J Allergy Clin Immunol. 2012 Feb; 129(2):575-8, 578.e1-9. PMID: 22070912.
      View in: PubMed
    51. Howard TD, Ho SM, Zhang L, Chen J, Cui W, Slager R, Gray S, Hawkins GA, Medvedovic M, Wagner JD. Epigenetic changes with dietary soy in cynomolgus monkeys. PLoS One. 2011; 6(10):e26791. PMID: 22046358.
      View in: PubMed
    52. Hixson JE, Shimmin LC, Montasser ME, Kim DK, Zhong Y, Ibarguen H, Follis J, Malcom G, Strong J, Howard T, Langefeld C, Liu Y, Rotter JI, Johnson C, Herrington D. Common variants in the periostin gene influence development of atherosclerosis in young persons. Arterioscler Thromb Vasc Biol. 2011 Jul; 31(7):1661-7. PMID: 21474826.
      View in: PubMed
    53. Li X, Howard TD, Moore WC, Ampleford EJ, Li H, Busse WW, Calhoun WJ, Castro M, Chung KF, Erzurum SC, Fitzpatrick AM, Gaston B, Israel E, Jarjour NN, Teague WG, Wenzel SE, Peters SP, Hawkins GA, Bleecker ER, Meyers DA. Importance of hedgehog interacting protein and other lung function genes in asthma. J Allergy Clin Immunol. 2011 Jun; 127(6):1457-65. PMID: 21397937.
      View in: PubMed
    54. Gray SB, Langefeld CD, Ziegler JT, Hawkins GA, Wagner JD, Howard TD. Single-nucleotide polymorphisms in the TNF gene are associated with obesity-related phenotypes in vervet monkeys. Obesity (Silver Spring). 2011 Jul; 19(7):1427-32. PMID: 21331060.
      View in: PubMed
    55. Mirabelli MC, Hoppin JA, Chatterjee AB, Isom S, Chen H, Grzywacz JG, Howard TD, Quandt SA, Vallejos QM, Arcury TA. Job activities and respiratory symptoms among farmworkers in North Carolina. Arch Environ Occup Health. 2011; 66(3):178-82. PMID: 21864106.
      View in: PubMed
    56. Rossouw J, Bray P, Liu J, Kooperberg C, Hsia J, Lewis C, Cushman M, Bonds D, Hendrix S, Papanicolaou G, Howard T, Herrington D. Estrogen receptor polymorphisms and the vascular effects of hormone therapy. Arterioscler Thromb Vasc Biol. 2011 Feb; 31(2):464-9. PMID: 21106950.
      View in: PubMed
    57. Howard TD, Hsu FC, Grzywacz JG, Chen H, Quandt SA, Vallejos QM, Whalley LE, Cui W, Padilla S, Arcury TA. Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE. Environ Health Perspect. 2010 Oct; 118(10):1395-9. PMID: 20529763.
      View in: PubMed
    58. Shashi V, Howard TD, Keshavan MS, Kaczorowski J, Berry MN, Schoch K, Spence EJ, Kwapil TR. COMT and anxiety and cognition in children with chromosome 22q11.2 deletion syndrome. Psychiatry Res. 2010 Jul 30; 178(2):433-6. PMID: 20488547.
      View in: PubMed
    59. Bottema RW, Nolte IM, Howard TD, Koppelman GH, Dubois AE, de Meer G, Kerkhof M, Bleecker ER, Meyers DA, Postma DS. Interleukin 13 and interleukin 4 receptor-a polymorphisms in rhinitis and asthma. Int Arch Allergy Immunol. 2010; 153(3):259-67. PMID: 20484924.
      View in: PubMed
    60. Cann JA, Kavanagh K, Jorgensen MJ, Mohanan S, Howard TD, Gray SB, Hawkins GA, Fairbanks LA, Wagner JD. Clinicopathologic characterization of naturally occurring diabetes mellitus in vervet monkeys. Vet Pathol. 2010 Jul; 47(4):713-8. PMID: 20460450.
      View in: PubMed
    61. Li X, Howard TD, Zheng SL, Haselkorn T, Peters SP, Meyers DA, Bleecker ER. Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions. J Allergy Clin Immunol. 2010 Feb; 125(2):328-335.e11. PMID: 20159242.
      View in: PubMed
    62. Shashi V, Kwapil TR, Kaczorowski J, Berry MN, Santos CS, Howard TD, Goradia D, Prasad K, Vaibhav D, Rajarethinam R, Spence E, Keshavan MS. Evidence of gray matter reduction and dysfunction in chromosome 22q11.2 deletion syndrome. Psychiatry Res. 2010 Jan 30; 181(1):1-8. PMID: 19962860.
      View in: PubMed
    63. Mez JB, Cole JW, Howard TD, Macclellan LR, Stine OC, O'Connell JR, Wozniak MA, Stern BJ, Sorkin JD, Mitchell BD, Kittner SJ. Evaluation of self-reported ethnicity in a case-control population: the stroke prevention in young women study. BMC Res Notes. 2009 Dec 18; 2:260. PMID: 20021678.
      View in: PubMed
    64. Gray SB, Howard TD, Langefeld CD, Hawkins GA, Diallo AF, Wagner JD. Comparative analyses of single-nucleotide polymorphisms in the TNF promoter region provide further validation for the vervet monkey model of obesity. Comp Med. 2009 Dec; 59(6):580-8. PMID: 20034434.
      View in: PubMed
    65. Koppelman GH, Meyers DA, Howard TD, Zheng SL, Hawkins GA, Ampleford EJ, Xu J, Koning H, Bruinenberg M, Nolte IM, van Diemen CC, Boezen HM, Timens W, Whittaker PA, Stine OC, Barton SJ, Holloway JW, Holgate ST, Graves PE, Martinez FD, van Oosterhout AJ, Bleecker ER, Postma DS. Identification of PCDH1 as a novel susceptibility gene for bronchial hyperresponsiveness. Am J Respir Crit Care Med. 2009 Nov 15; 180(10):929-35. PMID: 19729670.
      View in: PubMed
    66. MacClellan LR, Howard TD, Cole JW, Stine OC, Giles WH, O'Connell JR, Wozniak MA, Stern BJ, Mitchell BD, Kittner SJ. Relation of candidate genes that encode for endothelial function to migraine and stroke: the Stroke Prevention in Young Women study. Stroke. 2009 Oct; 40(10):e550-7. PMID: 19661472.
      View in: PubMed
    67. Lamon-Fava S, Asztalos BF, Howard TD, Reboussin DM, Horvath KV, Schaefer EJ, Herrington DM. Association of polymorphisms in genes involved in lipoprotein metabolism with plasma concentrations of remnant lipoproteins and HDL subpopulations before and after hormone therapy in postmenopausal women. Clin Endocrinol (Oxf). 2010 Feb; 72(2):169-75. PMID: 19489872.
      View in: PubMed
    68. Smith AK, Lange LA, Ampleford EJ, Meyers DA, Bleecker ER, Howard TD. Association of polymorphisms in CASP10 and CASP8 with FEV(1)/FVC and bronchial hyperresponsiveness in ethnically diverse asthmatics. Clin Exp Allergy. 2008 Nov; 38(11):1738-44. PMID: 18823309.
      View in: PubMed
    69. Liu Y, Freedman BI, Burdon KP, Langefeld CD, Howard T, Herrington D, Goff DC, Bowden DW, Wagenknecht LE, Hedrick CC, Rich SS. Association of arachidonate 12-lipoxygenase genotype variation and glycemic control with albuminuria in type 2 diabetes. Am J Kidney Dis. 2008 Aug; 52(2):242-50. PMID: 18640486.
      View in: PubMed
    70. Tseng ZH, Aouizerat BE, Pawlikowska L, Vittinghoff E, Lin F, Whiteman D, Poon A, Herrington D, Howard TD, Varosy PD, Hulley SB, Malloy M, Kane J, Kwok PY, Olgin JE. Common beta-adrenergic receptor polymorphisms are not associated with risk of sudden cardiac death in patients with coronary artery disease. Heart Rhythm. 2008 Jun; 5(6):814-21. PMID: 18534365.
      View in: PubMed
    71. Lakoski SG, Li L, Langefeld CD, Liu Y, Howard TD, Brosnihan KB, Xu J, Bowden DW, Herrington DM. The association between innate immunity gene (IRAK1) and C-reactive protein in the Diabetes Heart Study. Exp Mol Pathol. 2007 Jun; 82(3):280-3. PMID: 17382928.
      View in: PubMed
    72. Bray PF, Howard TD, Vittinghoff E, Sane DC, Herrington DM. Effect of genetic variations in platelet glycoproteins Ibalpha and VI on the risk for coronary heart disease events in postmenopausal women taking hormone therapy. Blood. 2007 Mar 01; 109(5):1862-9. PMID: 17105818.
      View in: PubMed
    73. Shashi V, Keshavan MS, Howard TD, Berry MN, Basehore MJ, Lewandowski E, Kwapil TR. Cognitive correlates of a functional COMT polymorphism in children with 22q11.2 deletion syndrome. Clin Genet. 2006 Mar; 69(3):234-8. PMID: 16542388.
      View in: PubMed
    74. Dijkstra A, Howard TD, Vonk JM, Ampleford EJ, Lange LA, Bleecker ER, Meyers DA, Postma DS. Estrogen receptor 1 polymorphisms are associated with airway hyperresponsiveness and lung function decline, particularly in female subjects with asthma. J Allergy Clin Immunol. 2006 Mar; 117(3):604-11. PMID: 16522460.
      View in: PubMed
    75. Howard TD, Giles WH, Xu J, Wozniak MA, Malarcher AM, Lange LA, Macko RF, Basehore MJ, Meyers DA, Cole JW, Kittner SJ. Promoter polymorphisms in the nitric oxide synthase 3 gene are associated with ischemic stroke susceptibility in young black women. Stroke. 2005 Sep; 36(9):1848-51. PMID: 16100023.
      View in: PubMed
    76. Meyers DA, Postma DS, Stine OC, Koppelman GH, Ampleford EJ, Jongepier H, Howard TD, Bleecker ER. Genome screen for asthma and bronchial hyperresponsiveness: interactions with passive smoke exposure. J Allergy Clin Immunol. 2005 Jun; 115(6):1169-75. PMID: 15940130.
      View in: PubMed
    77. Postma DS, Meyers DA, Jongepier H, Howard TD, Koppelman GH, Bleecker ER. Genomewide screen for pulmonary function in 200 families ascertained for asthma. Am J Respir Crit Care Med. 2005 Aug 15; 172(4):446-52. PMID: 15901612.
      View in: PubMed
    78. Nicolae D, Cox NJ, Lester LA, Schneider D, Tan Z, Billstrand C, Kuldanek S, Donfack J, Kogut P, Patel NM, Goodenbour J, Howard T, Wolf R, Koppelman GH, White SR, Parry R, Postma DS, Meyers D, Bleecker ER, Hunt JS, Solway J, Ober C. Fine mapping and positional candidate studies identify HLA-G as an asthma susceptibility gene on chromosome 6p21. Am J Hum Genet. 2005 Feb; 76(2):349-57. PMID: 15611928.
      View in: PubMed
    79. Blaisdell CJ, Howard TD, Stern A, Bamford P, Bleecker ER, Stine OC. CLC-2 single nucleotide polymorphisms (SNPs) as potential modifiers of cystic fibrosis disease severity. BMC Med Genet. 2004 Oct 26; 5:26. PMID: 15507145.
      View in: PubMed
    80. Basehore MJ, Howard TD, Lange LA, Moore WC, Hawkins GA, Marshik PL, Harkins MS, Meyers DA, Bleecker ER. A comprehensive evaluation of IL4 variants in ethnically diverse populations: association of total serum IgE levels and asthma in white subjects. J Allergy Clin Immunol. 2004 Jul; 114(1):80-7. PMID: 15241348.
      View in: PubMed
    81. Hawkins GA, Amelung PJ, Smith RS, Jongepier H, Howard TD, Koppelman GH, Meyers DA, Bleecker ER, Postma DS. Identification of polymorphisms in the human glucocorticoid receptor gene (NR3C1) in a multi-racial asthma case and control screening panel. DNA Seq. 2004 Jun; 15(3):167-73. PMID: 15497438.
      View in: PubMed
    82. Jongepier H, Boezen HM, Dijkstra A, Howard TD, Vonk JM, Koppelman GH, Zheng SL, Meyers DA, Bleecker ER, Postma DS. Polymorphisms of the ADAM33 gene are associated with accelerated lung function decline in asthma. Clin Exp Allergy. 2004 May; 34(5):757-60. PMID: 15144468.
      View in: PubMed
    83. Korstanje R, Li R, Howard T, Kelmenson P, Marshall J, Paigen B, Churchill G. Influence of sex and diet on quantitative trait loci for HDL cholesterol levels in an SM/J by NZB/BlNJ intercross population. J Lipid Res. 2004 May; 45(5):881-8. PMID: 14993241.
      View in: PubMed
    84. Howard TD, Postma DS, Jongepier H, Moore WC, Koppelman GH, Zheng SL, Xu J, Bleecker ER, Meyers DA. Association of a disintegrin and metalloprotease 33 (ADAM33) gene with asthma in ethnically diverse populations. J Allergy Clin Immunol. 2003 Oct; 112(4):717-22. PMID: 14564349.
      View in: PubMed
    85. Herrington DM, Howard TD. From presumed benefit to potential harm--hormone therapy and heart disease. N Engl J Med. 2003 Aug 07; 349(6):519-21. PMID: 12904515.
      View in: PubMed
    86. Herrington DM, Howard TD. ER-alpha variants and the cardiovascular effects of hormone replacement therapy. Pharmacogenomics. 2003 May; 4(3):269-77. PMID: 12718718.
      View in: PubMed
    87. Cui Z, Willingham MC, Hicks AM, Alexander-Miller MA, Howard TD, Hawkins GA, Miller MS, Weir HM, Du W, DeLong CJ. Spontaneous regression of advanced cancer: identification of a unique genetically determined, age-dependent trait in mice. Proc Natl Acad Sci U S A. 2003 May 27; 100(11):6682-7. PMID: 12724523.
      View in: PubMed
    88. Howard TD, Meyers DA, Bleecker ER. Mapping susceptibility genes for allergic diseases. Chest. 2003 Mar; 123(3 Suppl):363S-8S. PMID: 12628976.
      View in: PubMed
    89. Howard TD, Postma DS, Hawkins GA, Koppelman GH, Zheng SL, Wysong AK, Xu J, Meyers DA, Bleecker ER. Fine mapping of an IgE-controlling gene on chromosome 2q: Analysis of CTLA4 and CD28. J Allergy Clin Immunol. 2002 Nov; 110(5):743-51. PMID: 12417883.
      View in: PubMed
    90. Xu J, Bleecker ER, Jongepier H, Howard TD, Koppelman GH, Postma DS, Meyers DA. Major recessive gene(s) with considerable residual polygenic effect regulating adult height: confirmation of genomewide scan results for chromosomes 6, 9, and 12. Am J Hum Genet. 2002 Sep; 71(3):646-50. PMID: 12119602.
      View in: PubMed
    91. Herrington DM, Vittinghoff E, Howard TD, Major DA, Owen J, Reboussin DM, Bowden D, Bittner V, Simon JA, Grady D, Hulley SB. Factor V Leiden, hormone replacement therapy, and risk of venous thromboembolic events in women with coronary disease. Arterioscler Thromb Vasc Biol. 2002 Jun 01; 22(6):1012-7. PMID: 12067913.
      View in: PubMed
    92. Herrington DM, Howard TD, Brosnihan KB, McDonnell DP, Li X, Hawkins GA, Reboussin DM, Xu J, Zheng SL, Meyers DA, Bleecker ER. Common estrogen receptor polymorphism augments effects of hormone replacement therapy on E-selectin but not C-reactive protein. Circulation. 2002 Apr 23; 105(16):1879-82. PMID: 11997270.
      View in: PubMed
    93. Herrington DM, Howard TD, Hawkins GA, Reboussin DM, Xu J, Zheng SL, Brosnihan KB, Meyers DA, Bleecker ER. Estrogen-receptor polymorphisms and effects of estrogen replacement on high-density lipoprotein cholesterol in women with coronary disease. N Engl J Med. 2002 Mar 28; 346(13):967-74. PMID: 11919305.
      View in: PubMed
    94. Koppelman GH, Stine OC, Xu J, Howard TD, Zheng SL, Kauffman HF, Bleecker ER, Meyers DA, Postma DS. Genome-wide search for atopy susceptibility genes in Dutch families with asthma. J Allergy Clin Immunol. 2002 Mar; 109(3):498-506. PMID: 11897998.
      View in: PubMed
    95. Howard TD, Koppelman GH, Xu J, Zheng SL, Postma DS, Meyers DA, Bleecker ER. Gene-gene interaction in asthma: IL4RA and IL13 in a Dutch population with asthma. Am J Hum Genet. 2002 Jan; 70(1):230-6. PMID: 11709756.
      View in: PubMed
    96. Howard TD, Whittaker PA, Zaiman AL, Koppelman GH, Xu J, Hanley MT, Meyers DA, Postma DS, Bleecker ER. Identification and association of polymorphisms in the interleukin-13 gene with asthma and atopy in a Dutch population. Am J Respir Cell Mol Biol. 2001 Sep; 25(3):377-84. PMID: 11588017.
      View in: PubMed
    97. Xu J, Meyers DA, Ober C, Blumenthal MN, Mellen B, Barnes KC, King RA, Lester LA, Howard TD, Solway J, Langefeld CD, Beaty TH, Rich SS, Bleecker ER, Cox NJ. Genomewide screen and identification of gene-gene interactions for asthma-susceptibility loci in three U.S. populations: collaborative study on the genetics of asthma. Am J Hum Genet. 2001 Jun; 68(6):1437-46. PMID: 11349227.
      View in: PubMed
    98. Koppelman GH, Reijmerink NE, Colin Stine O, Howard TD, Whittaker PA, Meyers DA, Postma DS, Bleecker ER. Association of a promoter polymorphism of the CD14 gene and atopy. Am J Respir Crit Care Med. 2001 Mar; 163(4):965-9. PMID: 11282774.
      View in: PubMed
    99. Xu J, Postma DS, Howard TD, Koppelman GH, Zheng SL, Stine OC, Bleecker ER, Meyers DA. Major genes regulating total serum immunoglobulin E levels in families with asthma. Am J Hum Genet. 2000 Nov; 67(5):1163-73. PMID: 11023809.
      View in: PubMed
    100. Howard TD, Meyers DA, Bleecker ER. Mapping susceptibility genes for asthma and allergy. J Allergy Clin Immunol. 2000 Feb; 105(2 Pt 2):S477-81. PMID: 10669527.
      View in: PubMed
    101. Ober C, Leavitt SA, Tsalenko A, Howard TD, Hoki DM, Daniel R, Newman DL, Wu X, Parry R, Lester LA, Solway J, Blumenthal M, King RA, Xu J, Meyers DA, Bleecker ER, Cox NJ. Variation in the interleukin 4-receptor alpha gene confers susceptibility to asthma and atopy in ethnically diverse populations. Am J Hum Genet. 2000 Feb; 66(2):517-26. PMID: 10677312.
      View in: PubMed
    102. Price JA, Brewer CS, Howard TD, Fossey SC, Sale MM, Ji L, Krolewski AS, Bowden DW. A physical map of the 20q12-q13.1 region associated with type 2 diabetes. Genomics. 1999 Dec 01; 62(2):208-15. PMID: 10610714.
      View in: PubMed
    103. Howard TD, Wiesch DG, Koppelman GH, Postma DS, Meyers DA, Bleecker ER. Genetics of allergy and bronchial hyperresponsiveness. Clin Exp Allergy. 1999 Jun; 29 Suppl 2:86-9. PMID: 10421829.
      View in: PubMed
    104. Howard TD, Bleecker ER, Stine OC. Fluorescent allele-specific PCR (FAS-PCR) improves the reliability of single nucleotide polymorphism screening. Biotechniques. 1999 Mar; 26(3):380-1. PMID: 10090967.
      View in: PubMed
    105. Paznekas WA, Cunningham ML, Howard TD, Korf BR, Lipson MH, Grix AW, Feingold M, Goldberg R, Borochowitz Z, Aleck K, Mulliken J, Yin M, Jabs EW. Genetic heterogeneity of Saethre-Chotzen syndrome, due to TWIST and FGFR mutations. Am J Hum Genet. 1998 Jun; 62(6):1370-80. PMID: 9585583.
      View in: PubMed
    106. Howard TD, Guttmacher AE, McKinnon W, Sharma M, McKusick VA, Jabs EW. Autosomal dominant postaxial polydactyly, nail dystrophy, and dental abnormalities map to chromosome 4p16, in the region containing the Ellis-van Creveld syndrome locus. Am J Hum Genet. 1997 Dec; 61(6):1405-12. PMID: 9399901.
      View in: PubMed
    107. Sale MM, Akamizu T, Howard TD, Yokota T, Nakao K, Mori T, Iwasaki H, Rich SS, Jennings-Gee JE, Yamada M, Bowden DW. Association of autoimmune thyroid disease with a microsatellite marker for the thyrotropin receptor gene and CTLA-4 in a Japanese population. Proc Assoc Am Physicians. 1997 Sep; 109(5):453-61. PMID: 9285944.
      View in: PubMed
    108. Bowden DW, Sale M, Howard TD, Qadri A, Spray BJ, Rothschild CB, Akots G, Rich SS, Freedman BI. Linkage of genetic markers on human chromosomes 20 and 12 to NIDDM in Caucasian sib pairs with a history of diabetic nephropathy. Diabetes. 1997 May; 46(5):882-6. PMID: 9133559.
      View in: PubMed
    109. Howard TD, Paznekas WA, Green ED, Chiang LC, Ma N, Ortiz de Luna RI, Garcia Delgado C, Gonzalez-Ramos M, Kline AD, Jabs EW. Mutations in TWIST, a basic helix-loop-helix transcription factor, in Saethre-Chotzen syndrome. Nat Genet. 1997 Jan; 15(1):36-41. PMID: 8988166.
      View in: PubMed
    110. Oldridge M, Lunt PW, Zackai EH, McDonald-McGinn DM, Muenke M, Moloney DM, Twigg SR, Heath JK, Howard TD, Hoganson G, Gagnon DM, Jabs EW, Wilkie AO. Genotype-phenotype correlation for nucleotide substitutions in the IgII-IgIII linker of FGFR2. Hum Mol Genet. 1997 Jan; 6(1):137-43. PMID: 9002682.
      View in: PubMed
    111. Howard TD, Akots G, Bowden DW. Physical and genetic mapping of the muscle phosphofructokinase gene (PFKM): reassignment to human chromosome 12q. Genomics. 1996 May 15; 34(1):122-7. PMID: 8661033.
      View in: PubMed
    112. Bowden DW, Krawchuk MD, Weaver EJ, Howard TD, Knowlton RG, Rao PN, Pettenati MJ, Hayworth R, Wagner BJ, Rothschild CB. D20S16 is a complex interspersed repeated sequence: genetic and physical analysis of the locus. Genomics. 1995 Jan 20; 25(2):394-403. PMID: 7789973.
      View in: PubMed
    113. Howard TD, Rothschild CB, Bowden DW. D20S213, a microsatellite polymorphism near the D20S16 locus. Hum Mol Genet. 1994 Apr; 3(4):677. PMID: 8069320.
      View in: PubMed
    114. Howard TD, Holzwarth G. Fluctuations in the velocity of individual DNA Molecules during agarose gel electrophoresis. Biophys J. 1992 Dec; 63(6):1487-92. PMID: 19431863.
      View in: PubMed
    Howard's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description
    Physical Neighbors Expand Description
    _