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Mark Chappell to Peptide Fragments

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This is a "connection" page, showing publications Mark Chappell has written about Peptide Fragments.
Mark Chappell
Connection Strength
8.919
Peptide Fragments
  1. Chappell MC, Pirro NT, South AM, Gwathmey TM. Concerns on the Specificity of Commercial ELISAs for the Measurement of Angiotensin (1-7) and Angiotensin II in Human Plasma. Hypertension. 2021 03 03; 77(3):e29-e31.
    View in: PubMed
    Score: 0.604
  2. South AM, Shaltout HA, Washburn LK, Hendricks AS, Diz DI, Chappell MC. Fetal programming and the angiotensin-(1-7) axis: a review of the experimental and clinical data. Clin Sci (Lond). 2019 01 15; 133(1):55-74.
    View in: PubMed
    Score: 0.526
  3. Yousif MHM, Benter IF, Diz DI, Chappell MC. Angiotensin-(1-7)-dependent vasorelaxation of the renal artery exhibits unique angiotensin and bradykinin receptor selectivity. Peptides. 2017 04; 90:10-16.
    View in: PubMed
    Score: 0.461
  4. Brosnihan KB, Chappell MC. Measurement of Angiotensin Peptides: HPLC-RIA. Methods Mol Biol. 2017; 1527:81-99.
    View in: PubMed
    Score: 0.457
  5. Cruz-Diaz N, Wilson BA, Pirro NT, Brosnihan KB, Marshall AC, Chappell MC. Identification of dipeptidyl peptidase 3 as the Angiotensin-(1-7) degrading peptidase in human HK-2 renal epithelial cells. Peptides. 2016 09; 83:29-37.
    View in: PubMed
    Score: 0.440
  6. Wilson BA, Nautiyal M, Gwathmey TM, Rose JC, Chappell MC. Evidence for a mitochondrial angiotensin-(1-7) system in the kidney. Am J Physiol Renal Physiol. 2016 04 01; 310(7):F637-F645.
    View in: PubMed
    Score: 0.426
  7. Wilson BA, Cruz-Diaz N, Marshall AC, Pirro NT, Su Y, Gwathmey TM, Rose JC, Chappell MC. An angiotensin-(1-7) peptidase in the kidney cortex, proximal tubules, and human HK-2 epithelial cells that is distinct from insulin-degrading enzyme. Am J Physiol Renal Physiol. 2015 Mar 15; 308(6):F594-601.
    View in: PubMed
    Score: 0.399
  8. Alzayadneh EM, Chappell MC. Angiotensin-(1-7) abolishes AGE-induced cellular hypertrophy and myofibroblast transformation via inhibition of ERK1/2. Cell Signal. 2014 Dec; 26(12):3027-35.
    View in: PubMed
    Score: 0.390
  9. Marshall AC, Pirro NT, Rose JC, Diz DI, Chappell MC. Evidence for an angiotensin-(1-7) neuropeptidase expressed in the brain medulla and CSF of sheep. J Neurochem. 2014 Jul; 130(2):313-23.
    View in: PubMed
    Score: 0.379
  10. Marshall AC, Shaltout HA, Pirro NT, Rose JC, Diz DI, Chappell MC. Enhanced activity of an angiotensin-(1-7) neuropeptidase in glucocorticoid-induced fetal programming. Peptides. 2014 Feb; 52:74-81.
    View in: PubMed
    Score: 0.370
  11. Marshall AC, Shaltout HA, Pirro NT, Rose JC, Diz DI, Chappell MC. Antenatal betamethasone exposure is associated with lower ANG-(1-7) and increased ACE in the CSF of adult sheep. . 2013 Oct 01; 305(7):R679-88.
    View in: PubMed
    Score: 0.362
  12. Westwood BM, Chappell MC. Divergent pathways for the angiotensin-(1-12) metabolism in the rat circulation and kidney. Peptides. 2012 Jun; 35(2):190-5.
    View in: PubMed
    Score: 0.329
  13. Gwathmey TM, Pendergrass KD, Reid SD, Rose JC, Diz DI, Chappell MC. Angiotensin-(1-7)-angiotensin-converting enzyme 2 attenuates reactive oxygen species formation to angiotensin II within the cell nucleus. Hypertension. 2010 Jan; 55(1):166-71.
    View in: PubMed
    Score: 0.280
  14. Ferrario CM, Jessup J, Gallagher PE, Averill DB, Brosnihan KB, Ann Tallant E, Smith RD, Chappell MC. Effects of renin-angiotensin system blockade on renal angiotensin-(1-7) forming enzymes and receptors. Kidney Int. 2005 Nov; 68(5):2189-96.
    View in: PubMed
    Score: 0.211
  15. Modrall JG, Sadjadi J, Brosnihan KB, Gallagher PE, Yu CH, Kramer GL, Bernstein KE, Chappell MC. Depletion of tissue angiotensin-converting enzyme differentially influences the intrarenal and urinary expression of angiotensin peptides. Hypertension. 2004 Apr; 43(4):849-53.
    View in: PubMed
    Score: 0.188
  16. Chappell MC, Modrall JG, Diz DI, Ferrario CM. Novel aspects of the renal renin-angiotensin system: angiotensin-(1-7), ACE2 and blood pressure regulation. Contrib Nephrol. 2004; 143:77-89.
    View in: PubMed
    Score: 0.186
  17. Hendricks AS, Lawson MJ, Figueroa JP, Chappell MC, Diz DI, Shaltout HA. Central ANG-(1-7) infusion improves blood pressure regulation in antenatal betamethasone-exposed sheep and reveals sex-dependent effects on oxidative stress. . 2019 06 01; 316(6):H1458-H1467.
    View in: PubMed
    Score: 0.134
  18. Nautiyal M, Shaltout HA, Chappell MC, Diz DI. Comparison of Candesartan and Angiotensin-(1-7) Combination to Mito-TEMPO Treatment for Normalizing Blood Pressure and Sympathovagal Balance in (mREN2)27 Rats. J Cardiovasc Pharmacol. 2019 03; 73(3):143-148.
    View in: PubMed
    Score: 0.133
  19. Wester A, Devocelle M, Tallant EA, Chappell MC, Gallagher PE, Paradisi F. Stabilization of Angiotensin-(1-7) by key substitution with a cyclic non-natural amino acid. Amino Acids. 2017 10; 49(10):1733-1742.
    View in: PubMed
    Score: 0.119
  20. Su Y, Bi J, Pulgar VM, Chappell MC, Rose JC. Antenatal betamethasone attenuates the angiotensin-(1-7)-Mas receptor-nitric oxide axis in isolated proximal tubule cells. Am J Physiol Renal Physiol. 2017 06 01; 312(6):F1056-F1062.
    View in: PubMed
    Score: 0.115
  21. Wilson BA, Chappell MC. Assessment of the Renin-Angiotensin System in Cellular Organelle: New Arenas for Study in the Mitochondria. Methods Mol Biol. 2017; 1614:99-121.
    View in: PubMed
    Score: 0.114
  22. Alzayadneh EM, Chappell MC. Nuclear expression of renin-angiotensin system components in NRK-52E renal epithelial cells. J Renin Angiotensin Aldosterone Syst. 2015 Dec; 16(4):1135-48.
    View in: PubMed
    Score: 0.096
  23. Wilson BA, Marshall AC, Alzayadneh EM, Chappell MC. The ins and outs of angiotensin processing within the kidney. . 2014 Sep 01; 307(5):R487-9.
    View in: PubMed
    Score: 0.096
  24. Nautiyal M, Shaltout HA, de Lima DC, do Nascimento K, Chappell MC, Diz DI. Response to Angiotensin-(1-7) and Bradykinin in Baroreceptor Reflex Sensitivity in Hypertension. Hypertension. 2013 Feb; 61(2):e20.
    View in: PubMed
    Score: 0.087
  25. Bi J, Contag SA, Carey LC, Tang L, Valego NK, Chappell MC, Rose JC. Antenatal betamethasone exposure alters renal responses to angiotensin-(1-7) in uninephrectomized adult male sheep. J Renin Angiotensin Aldosterone Syst. 2013 Dec; 14(4):290-8.
    View in: PubMed
    Score: 0.086
  26. Nautiyal M, Shaltout HA, de Lima DC, do Nascimento K, Chappell MC, Diz DI. Central angiotensin-(1-7) improves vagal function independent of blood pressure in hypertensive (mRen2)27 rats. Hypertension. 2012 Nov; 60(5):1257-65.
    View in: PubMed
    Score: 0.085
  27. Garcia-Espinosa MA, Shaltout HA, Gallagher PE, Chappell MC, Diz DI. In vivo expression of angiotensin-(1-7) lowers blood pressure and improves baroreflex function in transgenic (mRen2)27 rats. J Cardiovasc Pharmacol. 2012 Aug; 60(2):150-7.
    View in: PubMed
    Score: 0.084
  28. Yamaleyeva LM, Gilliam-Davis S, Almeida I, Brosnihan KB, Lindsey SH, Chappell MC. Differential regulation of circulating and renal ACE2 and ACE in hypertensive mRen2.Lewis rats with early-onset diabetes. Am J Physiol Renal Physiol. 2012 Jun 01; 302(11):F1374-84.
    View in: PubMed
    Score: 0.082
  29. Shaltout HA, Rose JC, Chappell MC, Diz DI. Angiotensin-(1-7) deficiency and baroreflex impairment precede the antenatal Betamethasone exposure-induced elevation in blood pressure. Hypertension. 2012 Feb; 59(2):453-8.
    View in: PubMed
    Score: 0.081
  30. Ahmad S, Simmons T, Varagic J, Moniwa N, Chappell MC, Ferrario CM. Chymase-dependent generation of angiotensin II from angiotensin-(1-12) in human atrial tissue. PLoS One. 2011; 6(12):e28501.
    View in: PubMed
    Score: 0.081
  31. Benter IF, Yousif MH, Al-Saleh FM, Raghupathy R, Chappell MC, Diz DI. Angiotensin-(1-7) blockade attenuates captopril- or hydralazine-induced cardiovascular protection in spontaneously hypertensive rats treated with NG-nitro-L-arginine methyl ester. J Cardiovasc Pharmacol. 2011 May; 57(5):559-67.
    View in: PubMed
    Score: 0.077
  32. Ahmad S, Varagic J, Westwood BM, Chappell MC, Ferrario CM. Uptake and metabolism of the novel peptide angiotensin-(1-12) by neonatal cardiac myocytes. PLoS One. 2011 Jan 10; 6(1):e15759.
    View in: PubMed
    Score: 0.076
  33. Chappell MC. Angiotensin-converting enzyme 2 autoantibodies: further evidence for a role of the renin-angiotensin system in inflammation. Arthritis Res Ther. 2010; 12(3):128.
    View in: PubMed
    Score: 0.073
  34. Arnold AC, Isa K, Shaltout HA, Nautiyal M, Ferrario CM, Chappell MC, Diz DI. Angiotensin-(1-12) requires angiotensin converting enzyme and AT1 receptors for cardiovascular actions within the solitary tract nucleus. . 2010 Sep; 299(3):H763-71.
    View in: PubMed
    Score: 0.073
  35. Dhaunsi GS, Yousif MH, Akhtar S, Chappell MC, Diz DI, Benter IF. Angiotensin-(1-7) prevents diabetes-induced attenuation in PPAR-gamma and catalase activities. Eur J Pharmacol. 2010 Jul 25; 638(1-3):108-14.
    View in: PubMed
    Score: 0.072
  36. Varagic J, Ahmad S, Brosnihan KB, Groban L, Chappell MC, Tallant EA, Gallagher PE, Ferrario CM. Decreased cardiac Ang-(1-7) is associated with salt-induced cardiac remodeling and dysfunction. Ther Adv Cardiovasc Dis. 2010 Feb; 4(1):17-25.
    View in: PubMed
    Score: 0.070
  37. Isa K, García-Espinosa MA, Arnold AC, Pirro NT, Tommasi EN, Ganten D, Chappell MC, Ferrario CM, Diz DI. Chronic immunoneutralization of brain angiotensin-(1-12) lowers blood pressure in transgenic (mRen2)27 hypertensive rats. . 2009 Jul; 297(1):R111-5.
    View in: PubMed
    Score: 0.067
  38. Ferrario CM, Varagic J, Habibi J, Nagata S, Kato J, Chappell MC, Trask AJ, Kitamura K, Whaley-Connell A, Sowers JR. Differential regulation of angiotensin-(1-12) in plasma and cardiac tissue in response to bilateral nephrectomy. . 2009 Apr; 296(4):H1184-92.
    View in: PubMed
    Score: 0.066
  39. Shaltout HA, Figueroa JP, Rose JC, Diz DI, Chappell MC. Alterations in circulatory and renal angiotensin-converting enzyme and angiotensin-converting enzyme 2 in fetal programmed hypertension. Hypertension. 2009 Feb; 53(2):404-8.
    View in: PubMed
    Score: 0.065
  40. Jessup JA, Trask AJ, Chappell MC, Nagata S, Kato J, Kitamura K, Ferrario CM. Localization of the novel angiotensin peptide, angiotensin-(1-12), in heart and kidney of hypertensive and normotensive rats. . 2008 Jun; 294(6):H2614-8.
    View in: PubMed
    Score: 0.062
  41. Trask AJ, Jessup JA, Chappell MC, Ferrario CM. Angiotensin-(1-12) is an alternate substrate for angiotensin peptide production in the heart. . 2008 May; 294(5):H2242-7.
    View in: PubMed
    Score: 0.062
  42. Garabelli PJ, Modrall JG, Penninger JM, Ferrario CM, Chappell MC. Distinct roles for angiotensin-converting enzyme 2 and carboxypeptidase A in the processing of angiotensins within the murine heart. Exp Physiol. 2008 May; 93(5):613-21.
    View in: PubMed
    Score: 0.062
  43. Benter IF, Yousif MH, Dhaunsi GS, Kaur J, Chappell MC, Diz DI. Angiotensin-(1-7) prevents activation of NADPH oxidase and renal vascular dysfunction in diabetic hypertensive rats. Am J Nephrol. 2008; 28(1):25-33.
    View in: PubMed
    Score: 0.060
  44. Yamaleyeva LM, Pendergrass KD, Pirro NT, Gallagher PE, Groban L, Chappell MC. Ovariectomy is protective against renal injury in the high-salt-fed older mRen2. Lewis rat. . 2007 Oct; 293(4):H2064-71.
    View in: PubMed
    Score: 0.059
  45. Trask AJ, Averill DB, Ganten D, Chappell MC, Ferrario CM. Primary role of angiotensin-converting enzyme-2 in cardiac production of angiotensin-(1-7) in transgenic Ren-2 hypertensive rats. . 2007 Jun; 292(6):H3019-24.
    View in: PubMed
    Score: 0.058
  46. Shaltout HA, Westwood BM, Averill DB, Ferrario CM, Figueroa JP, Diz DI, Rose JC, Chappell MC. Angiotensin metabolism in renal proximal tubules, urine, and serum of sheep: evidence for ACE2-dependent processing of angiotensin II. Am J Physiol Renal Physiol. 2007 Jan; 292(1):F82-91.
    View in: PubMed
    Score: 0.056
  47. Brosnihan KB, Neves LA, Chappell MC. Does the angiotensin-converting enzyme (ACE)/ACE2 balance contribute to the fate of angiotensin peptides in programmed hypertension? Hypertension. 2005 Nov; 46(5):1097-9.
    View in: PubMed
    Score: 0.053
  48. Gallagher PE, Chappell MC, Ferrario CM, Tallant EA. Distinct roles for ANG II and ANG-(1-7) in the regulation of angiotensin-converting enzyme 2 in rat astrocytes. . 2006 Feb; 290(2):C420-6.
    View in: PubMed
    Score: 0.052
  49. Averill DB, Ishiyama Y, Chappell MC, Ferrario CM. Cardiac angiotensin-(1-7) in ischemic cardiomyopathy. Circulation. 2003 Oct 28; 108(17):2141-6.
    View in: PubMed
    Score: 0.046
  50. Brosnihan KB, Neves LA, Joyner J, Averill DB, Chappell MC, Sarao R, Penninger J, Ferrario CM. Enhanced renal immunocytochemical expression of ANG-(1-7) and ACE2 during pregnancy. Hypertension. 2003 Oct; 42(4):749-53.
    View in: PubMed
    Score: 0.045
  51. Ferrario CM, Averill DB, Brosnihan KB, Chappell MC, Iskandar SS, Dean RH, Diz DI. Vasopeptidase inhibition and Ang-(1-7) in the spontaneously hypertensive rat. Kidney Int. 2002 Oct; 62(4):1349-57.
    View in: PubMed
    Score: 0.043
  52. South AM, Nixon PA, Chappell MC, Diz DI, Russell GB, Shaltout HA, O'Shea TM, Washburn LK. Obesity is Associated with Higher Blood Pressure and Higher Levels of Angiotensin II but Lower Angiotensin-(1-7) in Adolescents Born Preterm. J Pediatr. 2019 02; 205:55-60.e1.
    View in: PubMed
    Score: 0.032
  53. South AM, Nixon PA, Chappell MC, Diz DI, Russell GB, Snively BM, Shaltout HA, Rose JC, O'Shea TM, Washburn LK. Antenatal corticosteroids and the renin-angiotensin-aldosterone system in adolescents born preterm. Pediatr Res. 2017 01; 81(1-1):88-93.
    View in: PubMed
    Score: 0.028
  54. Bi J, Contag SA, Chen K, Su Y, Figueroa JP, Chappell MC, Rose JC. Sex-specific effect of antenatal betamethasone exposure on renal oxidative stress induced by angiotensins in adult sheep. Am J Physiol Renal Physiol. 2014 Nov 01; 307(9):F1013-22.
    View in: PubMed
    Score: 0.024
  55. Wang H, Jessup JA, Zhao Z, Da Silva J, Lin M, MacNamara LM, Ahmad S, Chappell MC, Ferrario CM, Groban L. Characterization of the cardiac renin angiotensin system in oophorectomized and estrogen-replete mRen2.Lewis rats. PLoS One. 2013; 8(10):e76992.
    View in: PubMed
    Score: 0.023
  56. Nautiyal M, Katakam PV, Busija DW, Gallagher PE, Tallant EA, Chappell MC, Diz DI. Differences in oxidative stress status and expression of MKP-1 in dorsal medulla of transgenic rats with altered brain renin-angiotensin system. . 2012 Oct 15; 303(8):R799-806.
    View in: PubMed
    Score: 0.021
  57. Isa K, Arnold AC, Westwood BM, Chappell MC, Diz DI. Angiotensin-converting enzyme inhibition, but not AT(1) receptor blockade, in the solitary tract nucleus improves baroreflex sensitivity in anesthetized transgenic hypertensive (mRen2)27 rats. Hypertens Res. 2011 Dec; 34(12):1257-62.
    View in: PubMed
    Score: 0.020
  58. Trask AJ, Groban L, Westwood BM, Varagic J, Ganten D, Gallagher PE, Chappell MC, Ferrario CM. Inhibition of angiotensin-converting enzyme 2 exacerbates cardiac hypertrophy and fibrosis in Ren-2 hypertensive rats. Am J Hypertens. 2010 Jun; 23(6):687-93.
    View in: PubMed
    Score: 0.018
  59. Tang L, Carey LC, Bi J, Valego N, Sun X, Deibel P, Perrott J, Figueroa JP, Chappell MC, Rose JC. Gender differences in the effects of antenatal betamethasone exposure on renal function in adult sheep. . 2009 Feb; 296(2):R309-17.
    View in: PubMed
    Score: 0.016
  60. Jessup JA, Gallagher PE, Averill DB, Brosnihan KB, Tallant EA, Chappell MC, Ferrario CM. Effect of angiotensin II blockade on a new congenic model of hypertension derived from transgenic Ren-2 rats. . 2006 Nov; 291(5):H2166-72.
    View in: PubMed
    Score: 0.014
  61. Ferrario CM, Jessup J, Chappell MC, Averill DB, Brosnihan KB, Tallant EA, Diz DI, Gallagher PE. Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2. Circulation. 2005 May 24; 111(20):2605-10.
    View in: PubMed
    Score: 0.013
  62. Neves LA, Averill DB, Ferrario CM, Chappell MC, Aschner JL, Walkup MP, Brosnihan KB. Characterization of angiotensin-(1-7) receptor subtype in mesenteric arteries. Peptides. 2003 Mar; 24(3):455-62.
    View in: PubMed
    Score: 0.011
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The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.