Martha Alexander-Miller to Animals
This is a "connection" page, showing publications Martha Alexander-Miller has written about Animals.
Connection Strength
2.105
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Shultz PK, Crofts KF, Holbrook BC, Alexander-Miller MA. Neuraminidase-specific antibody responses are generated in naive and vaccinated newborn nonhuman primates following virus infection. JCI Insight. 2020 12 17; 5(24).
Score: 0.080
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Alexander-Miller MA. Challenges for the Newborn Following Influenza Virus Infection and Prospects for an Effective Vaccine. Front Immunol. 2020; 11:568651.
Score: 0.079
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Holbrook BC, Alexander-Miller MA. Higher Frequency and Increased Expression of Molecules Associated with Suppression on T Regulatory Cells from Newborn Compared with Adult Nonhuman Primates. J Immunol. 2020 10 15; 205(8):2128-2136.
Score: 0.079
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Crofts KF, Holbrook BC, Soto-Pantoja DR, Ornelles DA, Alexander-Miller MA. TCR Dependent Metabolic Programming Regulates Autocrine IL-4 Production Resulting in Self-Tuning of the CD8+ T Cell Activation Setpoint. Front Immunol. 2020; 11:540.
Score: 0.077
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Westcott MM, Clemens EA, Holbrook BC, King SB, Alexander-Miller MA. The choice of linker for conjugating R848 to inactivated influenza virus determines the stimulatory capacity for innate immune cells. Vaccine. 2018 02 21; 36(9):1174-1182.
Score: 0.066
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Holbrook BC, Aycock ST, Machiele E, Clemens E, Gries D, Jorgensen MJ, Hadimani MB, King SB, Alexander-Miller MA. An R848 adjuvanted influenza vaccine promotes early activation of B cells in the draining lymph nodes of non-human primate neonates. Immunology. 2018 03; 153(3):357-367.
Score: 0.065
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Holbrook BC, D'Agostino RB, Tyler Aycock S, Jorgensen MJ, Hadimani MB, Bruce King S, Alexander-Miller MA. Adjuvanting an inactivated influenza vaccine with conjugated R848 improves the level of antibody present at 6months in a nonhuman primate neonate model. Vaccine. 2017 10 27; 35(45):6137-6142.
Score: 0.064
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Holbrook BC, D'Agostino RB, Parks GD, Alexander-Miller MA. Adjuvanting an inactivated influenza vaccine with flagellin improves the function and quantity of the long-term antibody response in a nonhuman primate neonate model. Vaccine. 2016 09 07; 34(39):4712-4717.
Score: 0.059
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Holbrook BC, Kim JR, Blevins LK, Jorgensen MJ, Kock ND, D'Agostino RB, Aycock ST, Hadimani MB, King SB, Parks GD, Alexander-Miller MA. A Novel R848-Conjugated Inactivated Influenza Virus Vaccine Is Efficacious and Safe in a Neonate Nonhuman Primate Model. J Immunol. 2016 07 15; 197(2):555-64.
Score: 0.059
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Kim JR, Holbrook BC, Hayward SL, Blevins LK, Jorgensen MJ, Kock ND, De Paris K, D'Agostino RB, Aycock ST, Mizel SB, Parks GD, Alexander-Miller MA. Inclusion of Flagellin during Vaccination against Influenza Enhances Recall Responses in Nonhuman Primate Neonates. J Virol. 2015 Jul; 89(14):7291-303.
Score: 0.054
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Holbrook BC, Hayward SL, Blevins LK, Kock N, Aycock T, Parks GD, Alexander-Miller MA. Nonhuman primate infants have an impaired respiratory but not systemic IgG antibody response following influenza virus infection. Virology. 2015 Feb; 476:124-133.
Score: 0.053
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Alexander-Miller MA. Vaccines against respiratory viral pathogens for use in neonates: opportunities and challenges. J Immunol. 2014 Dec 01; 193(11):5363-9.
Score: 0.053
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Blevins LK, Wren JT, Holbrook BC, Hayward SL, Swords WE, Parks GD, Alexander-Miller MA. Coinfection with Streptococcus pneumoniae negatively modulates the size and composition of the ongoing influenza-specific CD8? T cell response. J Immunol. 2014 Nov 15; 193(10):5076-87.
Score: 0.052
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Shiner EK, Holbrook BC, Alexander-Miller MA. CD4+ T cell subset differentiation and avidity setpoint are dictated by the interplay of cytokine and antigen mediated signals. PLoS One. 2014; 9(6):e100175.
Score: 0.051
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Parks GD, Alexander-Miller MA. Paramyxovirus activation and inhibition of innate immune responses. J Mol Biol. 2013 Dec 13; 425(24):4872-92.
Score: 0.049
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Holbrook BC, Yammani RD, Blevins LK, Alexander-Miller MA. In vivo modulation of avidity in highly sensitive CD8(+) effector T cells following viral infection. Viral Immunol. 2013 Oct; 26(5):302-13.
Score: 0.048
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Amoah S, Holbrook BC, Yammani RD, Alexander-Miller MA. High viral burden restricts short-lived effector cell number at late times postinfection through increased natural regulatory T cell expansion. J Immunol. 2013 May 15; 190(10):5020-9.
Score: 0.047
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Beauchamp NM, Yammani RD, Alexander-Miller MA. CD8 marks a subpopulation of lung-derived dendritic cells with differential responsiveness to viral infection and toll-like receptor stimulation. J Virol. 2012 Oct; 86(19):10640-50.
Score: 0.045
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Amoah S, Yammani RD, Grayson JM, Alexander-Miller MA. Changes in functional but not structural avidity during differentiation of CD8+ effector cells in vivo after virus infection. J Immunol. 2012 Jul 15; 189(2):638-45.
Score: 0.045
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Sharma SK, Alexander-Miller MA. Increased sensitivity to antigen in high avidity CD8(+) T cells results from augmented membrane proximal T-cell receptor signal transduction. Immunology. 2011 Jul; 133(3):307-17.
Score: 0.041
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Busick RY, Yammani RD, Alexander-Miller MA. Differentiation-dependent differences in murine T cell susceptibility to negative regulation by the lung. Am J Respir Cell Mol Biol. 2011 May; 44(5):597-605.
Score: 0.040
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Palmer EM, Holbrook BC, Arimilli S, Parks GD, Alexander-Miller MA. IFNgamma-producing, virus-specific CD8+ effector cells acquire the ability to produce IL-10 as a result of entry into the infected lung environment. Virology. 2010 Sep 01; 404(2):225-30.
Score: 0.039
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Beauchamp NM, Busick RY, Alexander-Miller MA. Functional divergence among CD103+ dendritic cell subpopulations following pulmonary poxvirus infection. J Virol. 2010 Oct; 84(19):10191-9.
Score: 0.039
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Arimilli S, Sharma SK, Yammani R, Reid SD, Parks GD, Alexander-Miller MA. Pivotal Advance: Nonfunctional lung effectors exhibit decreased calcium mobilization associated with reduced expression of ORAI1. J Leukoc Biol. 2010 Jun; 87(6):977-88.
Score: 0.038
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Yates NL, Yammani RD, Alexander-Miller MA. Dose-dependent lymphocyte apoptosis following respiratory infection with Vaccinia virus. Virus Res. 2008 Nov; 137(2):198-205.
Score: 0.034
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Yammani RD, Pejawar-Gaddy S, Gurley TC, Weimer ET, Hiltbold EM, Alexander-Miller MA. Regulation of maturation and activating potential in CD8+ versus CD8- dendritic cells following in vivo infection with vaccinia virus. Virology. 2008 Aug 15; 378(1):142-50.
Score: 0.034
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Kroger CJ, Amoah S, Alexander-Miller MA. Cutting edge: Dendritic cells prime a high avidity CTL response independent of the level of presented antigen. J Immunol. 2008 May 01; 180(9):5784-8.
Score: 0.034
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Arimilli S, Palmer EM, Alexander-Miller MA. Loss of function in virus-specific lung effector T cells is independent of infection. J Leukoc Biol. 2008 Mar; 83(3):564-74.
Score: 0.033
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Kroger CJ, Alexander-Miller MA. Cutting edge: CD8+ T cell clones possess the potential to differentiate into both high- and low-avidity effector cells. J Immunol. 2007 Jul 15; 179(2):748-51.
Score: 0.032
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Kroger CJ, Alexander-Miller MA. Dose-dependent modulation of CD8 and functional avidity as a result of peptide encounter. Immunology. 2007 Oct; 122(2):167-78.
Score: 0.031
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Pejawar-Gaddy S, Gitiban-Vaghefi N, Parks GD, Alexander-Miller MA. Distinct pathways for signaling maturation in macrophages and dendritic cells after infection with paramyxovirus simian virus 5. Viral Immunol. 2007; 20(1):76-87.
Score: 0.031
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Yates NL, Alexander-Miller MA. Vaccinia virus infection of mature dendritic cells results in activation of virus-specific naïve CD8+ T cells: a potential mechanism for direct presentation. Virology. 2007 Mar 15; 359(2):349-61.
Score: 0.030
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Pejawar-Gaddy S, Alexander-Miller MA. Ligation of CD80 is critical for high-level CD25 expression on CD8+ T lymphocytes. J Immunol. 2006 Oct 01; 177(7):4495-502.
Score: 0.030
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Pejawar SS, Parks GD, Alexander-Miller MA. Abortive versus productive viral infection of dendritic cells with a paramyxovirus results in differential upregulation of select costimulatory molecules. J Virol. 2005 Jun; 79(12):7544-57.
Score: 0.027
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Gray PM, Arimilli S, Palmer EM, Parks GD, Alexander-Miller MA. Altered function in CD8+ T cells following paramyxovirus infection of the respiratory tract. J Virol. 2005 Mar; 79(6):3339-49.
Score: 0.027
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Gray PM, Parks GD, Alexander-Miller MA. Modulation of CD8+ T cell avidity by increasing the turnover of viral antigen during infection. Cell Immunol. 2004 Sep-Oct; 231(1-2):14-9.
Score: 0.027
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Alexander-Miller MA. High-avidity CD8+ T cells: optimal soldiers in the war against viruses and tumors. Immunol Res. 2005; 31(1):13-24.
Score: 0.027
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Cawthon AG, Kroger CJ, Alexander-Miller MA. High avidity CD8+ T cells generated from CD28-deficient or wildtype mice exhibit a differential dependence on lipid raft integrity for activation. Cell Immunol. 2004 Feb; 227(2):148-55.
Score: 0.025
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Gray PM, Parks GD, Alexander-Miller MA. High avidity CD8+ T cells are the initial population elicited following viral infection of the respiratory tract. J Immunol. 2003 Jan 01; 170(1):174-81.
Score: 0.023
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Stirling ER, Terabe M, Wilson AS, Kooshki M, Yamaleyeva LM, Alexander-Miller MA, Zhang W, Miller LD, Triozzi PL, Soto-Pantoja DR. Targeting the CD47/thrombospondin-1 signaling axis regulates immune cell bioenergetics in the tumor microenvironment to potentiate antitumor immune response. J Immunother Cancer. 2022 Nov; 10(11).
Score: 0.023
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Cawthon AG, Alexander-Miller MA. Optimal colocalization of TCR and CD8 as a novel mechanism for the control of functional avidity. J Immunol. 2002 Oct 01; 169(7):3492-8.
Score: 0.023
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Parks GD, Alexander-Miller MA. High avidity cytotoxic T lymphocytes to a foreign antigen are efficiently activated following immunization with a recombinant paramyxovirus, simian virus 5. J Gen Virol. 2002 May; 83(Pt 5):1167-1172.
Score: 0.022
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Gray PM, Parks GD, Alexander-Miller MA. A novel CD8-independent high-avidity cytotoxic T-lymphocyte response directed against an epitope in the phosphoprotein of the paramyxovirus simian virus 5. J Virol. 2001 Nov; 75(21):10065-72.
Score: 0.021
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Cawthon AG, Lu H, Alexander-Miller MA. Peptide requirement for CTL activation reflects the sensitivity to CD3 engagement: correlation with CD8alphabeta versus CD8alphaalpha expression. J Immunol. 2001 Sep 01; 167(5):2577-84.
Score: 0.021
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Alexander-Miller MA. Differential expansion and survival of high and low avidity cytotoxic T cell populations during the immune response to a viral infection. Cell Immunol. 2000 Apr 10; 201(1):58-62.
Score: 0.019
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Alexander-Miller MA, Derby MA, Sarin A, Henkart PA, Berzofsky JA. Supraoptimal peptide-major histocompatibility complex causes a decrease in bc1-2 levels and allows tumor necrosis factor alpha receptor II-mediated apoptosis of cytotoxic T lymphocytes. J Exp Med. 1998 Oct 19; 188(8):1391-9.
Score: 0.017
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Martin AN, Alexander-Miller M, Yoza BK, Vachharajani V, McCall CE. Sirtuin1 Targeting Reverses Innate and Adaptive Immune Tolerance in Septic Mice. J Immunol Res. 2018; 2018:2402593.
Score: 0.017
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Wajih N, Basu S, Jailwala A, Kim HW, Ostrowski D, Perlegas A, Bolden CA, Buechler NL, Gladwin MT, Caudell DL, Rahbar E, Alexander-Miller MA, Vachharajani V, Kim-Shapiro DB. Potential therapeutic action of nitrite in sickle cell disease. Redox Biol. 2017 08; 12:1026-1039.
Score: 0.016
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Wren JT, Blevins LK, Pang B, Basu Roy A, Oliver MB, Reimche JL, Wozniak JE, Alexander-Miller MA, Swords WE. Pneumococcal Neuraminidase A (NanA) Promotes Biofilm Formation and Synergizes with Influenza A Virus in Nasal Colonization and Middle Ear Infection. Infect Immun. 2017 04; 85(4).
Score: 0.016
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Shewale SV, Brown AL, Bi X, Boudyguina E, Sawyer JK, Alexander-Miller MA, Parks JS. In vivo activation of leukocyte GPR120/FFAR4 by PUFAs has minimal impact on atherosclerosis in LDL receptor knockout mice. J Lipid Res. 2017 01; 58(1):236-246.
Score: 0.015
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Alexander-Miller MA, Leggatt GR, Sarin A, Berzofsky JA. Role of antigen, CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL. J Exp Med. 1996 Aug 01; 184(2):485-92.
Score: 0.015
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Alexander-Miller MA, Leggatt GR, Berzofsky JA. Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy. Proc Natl Acad Sci U S A. 1996 Apr 30; 93(9):4102-7.
Score: 0.015
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Wren JT, Blevins LK, Pang B, King LB, Perez AC, Murrah KA, Reimche JL, Alexander-Miller MA, Swords WE. Influenza A virus alters pneumococcal nasal colonization and middle ear infection independently of phase variation. Infect Immun. 2014 Nov; 82(11):4802-12.
Score: 0.013
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Alexander-Miller MA, Burke K, Koszinowski UH, Hansen TH, Connolly JM. Alloreactive cytotoxic T lymphocytes generated in the presence of viral-derived peptides show exquisite peptide and MHC specificity. J Immunol. 1993 Jul 01; 151(1):1-10.
Score: 0.012
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Brown AL, Zhu X, Rong S, Shewale S, Seo J, Boudyguina E, Gebre AK, Alexander-Miller MA, Parks JS. Omega-3 fatty acids ameliorate atherosclerosis by favorably altering monocyte subsets and limiting monocyte recruitment to aortic lesions. Arterioscler Thromb Vasc Biol. 2012 Sep; 32(9):2122-30.
Score: 0.011
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Johnson JB, Lyles DS, Alexander-Miller MA, Parks GD. Virion-associated complement regulator CD55 is more potent than CD46 in mediating resistance of mumps virus and vesicular stomatitis virus to neutralization. J Virol. 2012 Sep; 86(18):9929-40.
Score: 0.011
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Alexander MA, Damico CA, Wieties KM, Hansen TH, Connolly JM. Correlation between CD8 dependency and determinant density using peptide-induced, Ld-restricted cytotoxic T lymphocytes. J Exp Med. 1991 Apr 01; 173(4):849-58.
Score: 0.010
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Hicks AM, Riedlinger G, Willingham MC, Alexander-Miller MA, Von Kap-Herr C, Pettenati MJ, Sanders AM, Weir HM, Du W, Kim J, Simpson AJ, Old LJ, Cui Z. Transferable anticancer innate immunity in spontaneous regression/complete resistance mice. Proc Natl Acad Sci U S A. 2006 May 16; 103(20):7753-8.
Score: 0.007
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Cui Z, Willingham MC, Hicks AM, Alexander-Miller MA, Howard TD, Hawkins GA, Miller MS, Weir HM, Du W, DeLong CJ. Spontaneous regression of advanced cancer: identification of a unique genetically determined, age-dependent trait in mice. Proc Natl Acad Sci U S A. 2003 May 27; 100(11):6682-7.
Score: 0.006
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Spolski RJ, Alexander-Miller MA, Kuhn RE. Suppressed cytotoxic T lymphocyte responses in experimental cysticercosis. Vet Parasitol. 2002 Jul 02; 106(4):325-30.
Score: 0.006
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Derby MA, Snyder JT, Tse R, Alexander-Miller MA, Berzofsky JA. An abrupt and concordant initiation of apoptosis: antigen-dependent death of CD8+ CTL. Eur J Immunol. 2001 Oct; 31(10):2951-9.
Score: 0.005
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Leggatt GR, Alexander-Miller MA, Kumar A, Hoffman SL, Berzofsky JA. Cytotoxic T lymphocyte (CTL) adherence assay (CAA): a non-radioactive assay for murine CTL recognition of peptide-MHC class I complexes. J Immunol Methods. 1997 Feb 14; 201(1):1-10.
Score: 0.004
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Sarin A, Williams MS, Alexander-Miller MA, Berzofsky JA, Zacharchuk CM, Henkart PA. Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases. Immunity. 1997 Feb; 6(2):209-15.
Score: 0.004
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Goss JA, Alexander-Miller MA, Gorka J, Flye MW, Connolly JM, Hansen TH. Specific prolongation of allograft survival by a T-cell-receptor-derived peptide. Proc Natl Acad Sci U S A. 1993 Nov 01; 90(21):9872-6.
Score: 0.003
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Solheim JC, Alexander-Miller MA, Martinko JM, Connolly JM. Biased T cell receptor usage by Ld-restricted, tum- peptide-specific cytotoxic T lymphocyte clones. J Immunol. 1993 Feb 01; 150(3):800-11.
Score: 0.003
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Nuñez G, London L, Hockenbery D, Alexander M, McKearn JP, Korsmeyer SJ. Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines. J Immunol. 1990 May 01; 144(9):3602-10.
Score: 0.002