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Lawrence X. Webb MD

TitleProfessor Emeritus
InstitutionWake Forest School of Medicine
DepartmentDiagnostic Radiology
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    Other Positions
    TitleClinical Adjunct Faculty
    InstitutionWake Forest School of Medicine
    DepartmentOrthopedic Surgery


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Webb LX. The Impact of Negative Pressure Wound Therapy on Orthopaedic Infection. Orthop Clin North Am. 2017 Apr; 48(2):167-179. PMID: 28336040.
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    2. Schlatterer DR, Hirschfeld AG, Webb LX. Reply to the Letter to the Editor: Negative Pressure Wound Therapy in Grade IIIB Tibial Fractures: Fewer Infections and Fewer Flap Procedures? Clin Orthop Relat Res. 2016 Oct; 474(10):2317. PMID: 27439441.
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    3. Miller AN, Deal D, Green J, Houle T, Brown W, Thore C, Stump D, Webb LX. Use of the Reamer/Irrigator/Aspirator Decreases Carotid and Cranial Embolic Events in a Canine Model. J Bone Joint Surg Am. 2016 Apr 20; 98(8):658-64. PMID: 27098324.
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    4. Le TT, Vo HV, Webb LX. Investigation of Kryptoniteā„¢ bone cement in hybrid screw configurations of locking plate humeral midshaft fixation: A study of surrogate bone model. J Orthop. 2016 Sep; 13(3):157-61. PMID: 27408488.
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    5. Cook GE, Markel DC, Ren W, Webb LX, McKee MD, Schemitsch EH. Infection in Orthopaedics. J Orthop Trauma. 2015 Dec; 29 Suppl 12:S19-23. PMID: 26584261.
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    6. Schlatterer DR, Hirschfeld AG, Webb LX. Reply to Letter to the Editor: Negative Pressure Wound Therapy in Grade IIIB Tibial Fractures: Fewer Infections and Fewer Flap Procedures? Clin Orthop Relat Res. 2015 Nov; 473(11):3684. PMID: 26220896.
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    7. Schlatterer DR, Hirschfeld AG, Webb LX. Negative pressure wound therapy in grade IIIB tibial fractures: fewer infections and fewer flap procedures? Clin Orthop Relat Res. 2015 May; 473(5):1802-11. PMID: 25595096.
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    8. Langfitt M, Webb LX, Onwuchuruba C, Callahan M, Smith TL. Microvascular effects of subatmospheric pressure in striated muscle. J Reconstr Microsurg. 2013 Feb; 29(2):117-23. PMID: 23292989.
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    9. Garrett J, Halvorson J, Carroll E, Webb LX. Value of 3-D CT in classifying acetabular fractures during orthopedic residency training. Orthopedics. 2012 May; 35(5):e615-20. PMID: 22588400.
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    10. Wolinsky PR, Webb LX, Harvey EJ, Tejwani NC. The mangled limb: salvage versus amputation. Instr Course Lect. 2011; 60:27-34. PMID: 21553759.
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    11. Tejwani NC, Webb LX, Harvey EJ, Wolinsky PR. Soft-tissue management after trauma: initial management and wound coverage. Instr Course Lect. 2011; 60:15-25. PMID: 21553758.
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    12. Forsberg JA, Potter BK, Cierny G, Webb L. Diagnosis and management of chronic infection. J Am Acad Orthop Surg. 2011; 19 Suppl 1:S8-S19. PMID: 21304049.
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    13. Miclau T, Schmidt AH, Wenke JC, Webb LX, Harro JM, Prabhakara R, Shirtliff ME. Infection. J Orthop Trauma. 2010 Sep; 24(9):583-6. PMID: 20736799.
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    14. Reddix RN, Leng XI, Woodall J, Jackson B, Dedmond B, Webb LX. The effect of incisional negative pressure therapy on wound complications after acetabular fracture surgery. J Surg Orthop Adv. 2010; 19(2):91-7. PMID: 20727304.
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    15. Reddix RN, Tyler HK, Kulp B, Webb LX. Incisional vacuum-assisted wound closure in morbidly obese patients undergoing acetabular fracture surgery. Am J Orthop (Belle Mead NJ). 2009 Sep; 38(9):446-9. PMID: 19911098.
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    16. Reddix RN, Carroll E, Webb LX. Early diagnosis of a Morel-Lavallee lesion using three-dimensional computed tomography reconstructions: a case report. J Trauma. 2009 Aug; 67(2):E57-9. PMID: 19065111.
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    17. Coldren FM, Palavecino EL, Levi-Polyachenko NH, Wagner WD, Smith TL, Smith BP, Webb LX, Carroll DL. Encapsulated Staphylococcus aureus strains vary in adhesiveness assessed by atomic force microscopy. J Biomed Mater Res A. 2009 May; 89(2):402-10. PMID: 18431772.
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    18. Reddix RN, Russell G, Woodall J, Jackson B, Dedmond B, Webb LX. Relationship between intraoperative femoral head bleeding and development of avascular necrosis after acetabular fracture surgery. J Surg Orthop Adv. 2009; 18(3):129-33. PMID: 19843437.
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    19. Pilson HT, Reddix RN, Mutty CE, Webb LX. The long lost art of preoperative planning--resurrected? Orthopedics. 2008 Dec; 31(12). PMID: 19226056.
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    20. Castillo RC, MacKenzie EJ, Archer KR, Bosse MJ, Webb LX. Evidence of beneficial effect of physical therapy after lower-extremity trauma. Arch Phys Med Rehabil. 2008 Oct; 89(10):1873-9. PMID: 18929015.
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    21. Webb LX, Pape HC. Current thought regarding the mechanism of action of negative pressure wound therapy with reticulated open cell foam. J Orthop Trauma. 2008; 22(10 Suppl):S135-7. PMID: 19034159.
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    22. Pape HC, Webb LX. History of open wound and fracture treatment. J Orthop Trauma. 2008; 22(10 Suppl):S133-4. PMID: 19034158.
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    23. MacKenzie EJ, Jones AS, Bosse MJ, Castillo RC, Pollak AN, Webb LX, Swiontkowski MF, Kellam JF, Smith DG, Sanders RW, Jones AL, Starr AJ, McAndrew MP, Patterson BM, Burgess AR. Health-care costs associated with amputation or reconstruction of a limb-threatening injury. J Bone Joint Surg Am. 2007 Aug; 89(8):1685-92. PMID: 17671005.
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    24. Webb LX, Bosse MJ, Castillo RC, MacKenzie EJ. Analysis of surgeon-controlled variables in the treatment of limb-threatening type-III open tibial diaphyseal fractures. J Bone Joint Surg Am. 2007 May; 89(5):923-8. PMID: 17473126.
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    25. Dedmond BT, Kortesis B, Punger K, Simpson J, Argenta J, Kulp B, Morykwas M, Webb LX. The use of negative-pressure wound therapy (NPWT) in the temporary treatment of soft-tissue injuries associated with high-energy open tibial shaft fractures. J Orthop Trauma. 2007 Jan; 21(1):11-7. PMID: 17211263.
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    26. Webb LX, Wagner W, Carroll D, Tyler H, Coldren F, Martin E. Osteomyelitis and intraosteoblastic Staphylococcus aureus. J Surg Orthop Adv. 2007; 16(2):73-8. PMID: 17592714.
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    27. Reddix RN, Webb LX. Computer-assisted preoperative planning in the surgical treatment of acetabular fractures. J Surg Orthop Adv. 2007; 16(3):138-43. PMID: 17963657.
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    28. Dedmond BT, Kortesis B, Punger K, Simpson J, Argenta J, Kulp B, Morykwas M, Webb LX. Subatmospheric pressure dressings in the temporary treatment of soft tissue injuries associated with type III open tibial shaft fractures in children. J Pediatr Orthop. 2006 Nov-Dec; 26(6):728-32. PMID: 17065934.
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    29. MacKenzie EJ, Bosse MJ, Kellam JF, Pollak AN, Webb LX, Swiontkowski MF, Smith DG, Sanders RW, Jones AL, Starr AJ, McAndrew MP, Patterson BM, Burgess AR, Travison T, Castillo RC. Early predictors of long-term work disability after major limb trauma. J Trauma. 2006 Sep; 61(3):688-94. PMID: 16967009.
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    30. Jones AL, Bucholz RW, Bosse MJ, Mirza SK, Lyon TR, Webb LX, Pollak AN, Golden JD, Valentin-Opran A. Recombinant human BMP-2 and allograft compared with autogenous bone graft for reconstruction of diaphyseal tibial fractures with cortical defects. A randomized, controlled trial. J Bone Joint Surg Am. 2006 Jul; 88(7):1431-41. PMID: 16818967.
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    31. Yang CC, Chang DS, Webb LX. Vacuum-assisted closure for fasciotomy wounds following compartment syndrome of the leg. J Surg Orthop Adv. 2006; 15(1):19-23. PMID: 16603108.
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    32. Ellington JK, Harris M, Hudson MC, Vishin S, Webb LX, Sherertz R. Intracellular Staphylococcus aureus and antibiotic resistance: implications for treatment of staphylococcal osteomyelitis. J Orthop Res. 2006 Jan; 24(1):87-93. PMID: 16419973.
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    33. Webb LX, Dedmond B, Schlatterer D, Laverty D. The contaminated high-energy open fracture: a protocol to prevent and treat inflammatory mediator storm-induced soft-tissue compartment syndrome (IMSICS). J Am Acad Orthop Surg. 2006; 14(10 Spec No.):S82-6. PMID: 17003216.
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    34. Bosse MJ, McCarthy ML, Jones AL, Webb LX, Sims SH, Sanders RW, MacKenzie EJ. The insensate foot following severe lower extremity trauma: an indication for amputation? J Bone Joint Surg Am. 2005 Dec; 87(12):2601-2608. PMID: 16322607.
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    35. Castillo RC, MacKenzie EJ, Webb LX, Bosse MJ, Avery J. Use and perceived need of physical therapy following severe lower-extremity trauma. Arch Phys Med Rehabil. 2005 Sep; 86(9):1722-8. PMID: 16181933.
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    36. MacKenzie EJ, Bosse MJ, Pollak AN, Webb LX, Swiontkowski MF, Kellam JF, Smith DG, Sanders RW, Jones AL, Starr AJ, McAndrew MP, Patterson BM, Burgess AR, Castillo RC. Long-term persistence of disability following severe lower-limb trauma. Results of a seven-year follow-up. J Bone Joint Surg Am. 2005 Aug; 87(8):1801-9. PMID: 16085622.
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    37. Schlatterer D, Webb LX. Orthopedic indications for negative pressure wound therapy. Ostomy Wound Manage. 2005 Feb; 51(2A Suppl):27S-28S. PMID: 15699561.
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    38. MacKenzie EJ, Bosse MJ, Castillo RC, Smith DG, Webb LX, Kellam JF, Burgess AR, Swiontkowski MF, Sanders RW, Jones AL, McAndrew MP, Patterson BM, Travison TG, McCarthy ML. Functional outcomes following trauma-related lower-extremity amputation. J Bone Joint Surg Am. 2004 Aug; 86(8):1636-45. PMID: 15292410.
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    39. Lee CA, Birkedal JP, Dickerson EA, Vieta PA, Webb LX, Teasdall RD. Stabilization of Lisfranc joint injuries: a biomechanical study. Foot Ankle Int. 2004 May; 25(5):365-70. PMID: 15134620.
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    40. Webb LX, Laver D, DeFranzo A. Negative pressure wound therapy in the management of orthopedic wounds. Ostomy Wound Manage. 2004 Apr; 50(4A Suppl):26-7. PMID: 15317242.
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    41. Teasdall RD, Webb LX. Innovations in the management of hip fractures. Orthopedics. 2003 Aug; 26(8 Suppl):s843-9. PMID: 12934739.
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    42. Schmidt AH, Templeman DC, Tornetta P, Webb LX, Bone LB, Duwelius PJ. Anatomic assessment of the proper insertion site for a tibial intramedullary nail. J Orthop Trauma. 2003 Jan; 17(1):75-6. PMID: 12499974.
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    43. Bosse MJ, MacKenzie EJ, Kellam JF, Burgess AR, Webb LX, Swiontkowski MF, Sanders RW, Jones AL, McAndrew MP, Patterson BM, McCarthy ML, Travison TG, Castillo RC. An analysis of outcomes of reconstruction or amputation after leg-threatening injuries. N Engl J Med. 2002 Dec 12; 347(24):1924-31. PMID: 12477942.
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    44. MacKenzie EJ, Bosse MJ, Kellam JF, Burgess AR, Webb LX, Swiontkowski MF, Sanders R, Jones AL, McAndrew MP, Patterson B, McCarthy ML, Rohde CA. Factors influencing the decision to amputate or reconstruct after high-energy lower extremity trauma. J Trauma. 2002 Apr; 52(4):641-9. PMID: 11956376.
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    45. Webb LX. New techniques in wound management: vacuum-assisted wound closure. J Am Acad Orthop Surg. 2002; 10(5):303-11. PMID: 12374481.
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    46. Webb LX. Proximal femoral fractures. J South Orthop Assoc. 2002; 11(4):203-12. PMID: 12597064.
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