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Laura A. Flashman PhD, ABPP

TitleProfessor
InstitutionWake Forest School of Medicine
DepartmentNeurology, Neuropsychology
Address
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    Collapse Biography 
    Collapse education and training
    Middlebury College, Middlebury VTBA05/1984Psychology/Spanish
    Emory University, Atlanta GAMA05/1989Psychology
    Emory University, Atlanta GAPhD01/1993Clinical Psychology
    University of San Diego/VA Consortium, San Diego, CA6/30/19Clinical Internship
    Mental Health Clinical Research Center, University of Iowa, Iowa City, IA08/1/19Postdoctoral Fellowship in Neuropsychology
    Collapse awards and honors
    1980 - 1984National Merit Scholar, Middlebury College
    - 1984Phi Beta Kappa, Middlebury College
    - 1984Magna cum laude, Middlebury College
    - 1984High Honors in Psychology, Middlebury College
    - 1992Sigma Xi, National Psychology Honor Society, Emory University
    - 2013Outstanding Professional of the Year, Independent Services Network, Inc
    - 2018Ellen Hayes Award for Outstanding Volunteer Service, Brain Injury Association of New Hampshire
    - 2002Fellow, American Neuropsychiatric Association
    - 2012Fellow, American Psychological Association and Division 40
    - 2022Fellow, National Academy of Neuropsychology

    Collapse Research 
    Collapse research activities and funding
    NCT03777267     (Charles Tegeler)Jun 20, 2011 - Dec 31, 2023
    Susanne Marcus Collins Foundation, Inc
    Development of a University-based Research Program of Brainwave Optimization for Neurological & Cardiovascular Disorders
    Role: Role: Health Psychologist
    R21NS075791     (FLASHMAN, LAURA A)Sep 1, 2011 - Aug 31, 2015
    NIH
    HYBRID Diffusion Imaging to Detect Acute White Matter Injury After Mild TBI
    Role: Principal Investigator
    R01AG058921     (ALLRED, NICHOLETTE D)Mar 1, 2019 - Dec 31, 2023
    NIH
    Metabolomics of Neurocognitive Risk for Dementia in Diabetes
    Role: Co-Investigator
    10000669002     (Christopher Whitlow)Jul 1, 2020 - Nov 30, 2023
    Michael J. Fox Foundation
    Using Time-Varying Caloric Vestibular Stimulation to Improve Neurovascular Status in Parkinson's Disease
    Role Description: This study tests the hypothesis that time-varying caloric vestibular stimulation improves symptoms associated with Parkinson’s disease by modulating brain function.
    Role: Co-Investigator
    HD108530     (Jill Urgan)Oct 1, 2021 - Sep 30, 2023
    NICHHD
    Development of a biomechanically-based post-concussion return to play protocol for Gymnasts
    Role Description: This study will evaluate head kinematics in artistic gymnastics for the development of a biomechanically based post-concussion return to play protocol in the sport. The central hypothesis is that exposure to high rotational head motion during gymnastics maneuvers may provoke symptoms of concussion and affect cognition.
    Role: Neuropsychologist

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Filben TM, Pritchard NS, Oravec CS, Hile CW, Bercaw JR, Zoch SR, Miller LE, Bullock GS, Flashman LA, Miles CM, Urban JE, Stitzel JD. Pilot characterization of head kinematics in grassroots dirt track racing. Traffic Inj Prev. 2022; 23(sup1):S38-S43. PMID: 35939323.
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    2. Carmasin JS, Roth RM, Rabin LA, Englert JJ, Flashman LA, Saykin AJ. Stability of Subjective Executive Functioning in Older Adults with aMCI and Subjective Cognitive Decline. Arch Clin Neuropsychol. 2021 Jan 18. PMID: 33454755.
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    3. Merz ZC, Flashman LA, Ford JC, McDonald BC, McAllister TW. Comparison of season-long diffusivity measures in a cohort of non-concussed contact and non-contact athletes. J Clin Exp Neuropsychol. 2020 10; 42(8):811-821. PMID: 32893734.
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    4. Fisher LB, Bomyea J, Thomas G, Cheung JC, He F, Jain S, Flashman LA, Andaluz N, Coimbra R, George MS, Grant GA, Marx CE, McAllister TW, Shutter L, Lang AJ, Stein MB, Zafonte RD. Contributions of posttraumatic stress disorder (PTSD) and mild TBI (mTBI) history to suicidality in the INTRuST consortium. Brain Inj. 2020 08 23; 34(10):1339-1349. PMID: 32811203.
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    5. Flashman LA, McDonald BC, Ford JC, Kenny RM, Andrews KD, Saykin AJ, McAllister TW. Differential Effects of Pergolide and Bromocriptine on Working Memory Performance and Brain Activation after Mild Traumatic Brain Injury. J Neurotrauma. 2021 01 15; 38(2):225-234. PMID: 32635808.
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    6. Bomyea J, Flashman LA, Zafonte R, Andaluz N, Coimbra R, George MS, Grant GA, Marx CE, McAllister TW, Shutter L, Lang AJ, Stein MB. Associations between neuropsychiatric and health status outcomes in individuals with probable mTBI. Psychiatry Res. 2019 02; 272:531-539. PMID: 30616120.
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    7. Wu YC, Mustafi SM, Harezlak J, Kodiweera C, Flashman LA, McAllister TW. Hybrid Diffusion Imaging in Mild Traumatic Brain Injury. J Neurotrauma. 2018 10 15; 35(20):2377-2390. PMID: 29786463.
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    8. Lepage C, de Pierrefeu A, Koerte IK, Coleman MJ, Pasternak O, Grant G, Marx CE, Morey RA, Flashman LA, George MS, McAllister TW, Andaluz N, Shutter L, Coimbra R, Zafonte RD, Stein MB, Shenton ME, Bouix S. White matter abnormalities in mild traumatic brain injury with and without post-traumatic stress disorder: a subject-specific diffusion tensor imaging study. Brain Imaging Behav. 2018 Jun; 12(3):870-881. PMID: 28676987.
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    9. Mirzaalian H, Ning L, Savadjiev P, Pasternak O, Bouix S, Michailovich O, Karmacharya S, Grant G, Marx CE, Morey RA, Flashman LA, George MS, McAllister TW, Andaluz N, Shutter L, Coimbra R, Zafonte RD, Coleman MJ, Kubicki M, Westin CF, Stein MB, Shenton ME, Rathi Y. Multi-site harmonization of diffusion MRI data in a registration framework. Brain Imaging Behav. 2018 02; 12(1):284-295. PMID: 28176263.
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    10. Wylie GR, Flashman LA. Understanding the interplay between mild traumatic brain injury and cognitive fatigue: models and treatments. Concussion. 2017 Dec; 2(4):CNC50. PMID: 30202591.
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    11. Lantrip C, Gunning FM, Flashman L, Roth RM, Holtzheimer PE. Effects of Transcranial Magnetic Stimulation on the Cognitive Control of Emotion: Potential Antidepressant Mechanisms. J ECT. 2017 Jun; 33(2):73-80. PMID: 28072659.
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    12. McDonald BC, Flashman LA, Arciniegas DB, Ferguson RJ, Xing L, Harezlak J, Sprehn GC, Hammond FM, Maerlender AC, Kruck CL, Gillock KL, Frey K, Wall RN, Saykin AJ, McAllister TW. Methylphenidate and Memory and Attention Adaptation Training for Persistent Cognitive Symptoms after Traumatic Brain Injury: A Randomized, Placebo-Controlled Trial. Neuropsychopharmacology. 2017 Aug; 42(9):1766-1775. PMID: 27874023.
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    13. Schwartz ES, Erdodi L, Rodriguez N, Ghosh JJ, Curtain JR, Flashman LA, Roth RM. CVLT-II Forced Choice Recognition Trial as an Embedded Validity Indicator: A Systematic Review of the Evidence. J Int Neuropsychol Soc. 2016 09; 22(8):851-8. PMID: 27619108.
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    14. Shee K, Lucas A, Flashman LA, Nho K, Tsongalis GJ, McDonald BC, Saykin AJ, McAllister TW, Rhodes CH. Alpha-synuclein (SNCA) polymorphisms exert protective effects on memory after mild traumatic brain injury. Neurosci Lett. 2016 Sep 06; 630:241-246. PMID: 27478013.
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    15. Bujarski KA, Flashman L, Li Z, Tosteson TD, Jobst BC, Thadani VM, Kobylarz EJ, Roberts DW, Roth RM. Investigating social cognition in epilepsy using a naturalistic task. Epilepsia. 2016 09; 57(9):1515-20. PMID: 27461072.
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    16. Lang AJ, Schnurr PP, Jain S, He F, Walser RD, Bolton E, Benedek DM, Norman SB, Sylvers P, Flashman L, Strauss J, Raman R, Chard KM. Randomized controlled trial of acceptance and commitment therapy for distress and impairment in OEF/OIF/OND veterans. Psychol Trauma. 2017 Aug; 9(Suppl 1):74-84. PMID: 27322609.
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    17. Maerlender AC, Masterson CJ, James TD, Beckwith J, Brolinson PG, Crisco J, Duma S, Flashman LA, Greenwald R, Rowson S, Wilcox B, McAllister TW. Test-retest, retest, and retest: Growth curve models of repeat testing with Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT). J Clin Exp Neuropsychol. 2016 10; 38(8):869-74. PMID: 27266563.
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    18. Tayim FM, Flashman LA, Wright MJ, Roth RM, McAllister TW. Recovery of episodic memory subprocesses in mild and complicated mild traumatic brain injury at 1 and 12 months post injury. J Clin Exp Neuropsychol. 2016 11; 38(9):1005-14. PMID: 27191799.
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    19. Mirzaalian H, Ning L, Savadjiev P, Pasternak O, Bouix S, Michailovich O, Grant G, Marx CE, Morey RA, Flashman LA, George MS, McAllister TW, Andaluz N, Shutter L, Coimbra R, Zafonte RD, Coleman MJ, Kubicki M, Westin CF, Stein MB, Shenton ME, Rathi Y. Inter-site and inter-scanner diffusion MRI data harmonization. Neuroimage. 2016 07 15; 135:311-23. PMID: 27138209.
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    20. Zhao W, Ford JC, Flashman LA, McAllister TW, Ji S. White Matter Injury Susceptibility via Fiber Strain Evaluation Using Whole-Brain Tractography. J Neurotrauma. 2016 10 15; 33(20):1834-1847. PMID: 26782139.
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    21. Roth RM, Garlinghouse MA, Flashman LA, Koven NS, Pendergrass JC, Ford JC, McAllister TW, Saykin AJ. Apathy Is Associated With Ventral Striatum Volume in Schizophrenia Spectrum Disorder. J Neuropsychiatry Clin Neurosci. 2016; 28(3):191-4. PMID: 26900738.
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    22. McAllister TW, Zafonte R, Jain S, Flashman LA, George MS, Grant GA, He F, Lohr JB, Andaluz N, Summerall L, Paulus MP, Raman R, Stein MB. Randomized Placebo-Controlled Trial of Methylphenidate or Galantamine for Persistent Emotional and Cognitive Symptoms Associated with PTSD and/or Traumatic Brain Injury. Neuropsychopharmacology. 2016 Apr; 41(5):1191-8. PMID: 26361060.
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    23. Zagorchev L, Meyer C, Stehle T, Wenzel F, Young S, Peters J, Weese J, Paulsen K, Garlinghouse M, Ford J, Roth R, Flashman L, McAllister T. Differences in Regional Brain Volumes Two Months and One Year after Mild Traumatic Brain Injury. J Neurotrauma. 2016 Jan 01; 33(1):29-34. PMID: 25970552.
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    24. Wilcox BJ, Beckwith JG, Greenwald RM, Raukar NP, Chu JJ, McAllister TW, Flashman LA, Maerlender AC, Duhaime AC, Crisco JJ. Biomechanics of head impacts associated with diagnosed concussion in female collegiate ice hockey players. J Biomech. 2015 Jul 16; 48(10):2201-4. PMID: 25913243.
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    25. Smith AM, Stuart MJ, Dodick DW, Roberts WO, Alford PW, Ashare AB, Aubrey M, Benson BW, Burke CJ, Dick R, Eickhoff C, Emery CA, Flashman LA, Gaz D, Giza CC, Greenwald RM, Herring S, Hoshizaki TB, Hudziak JJ, Huston J, Krause D, LaVoi N, Leaf M, Leddy JJ, MacPherson A, McKee AC, Mihalik JP, Moessner AM, Montelpare WJ, Putukian M, Schneider KJ, Szalkowski R, Tabrum M, Whitehead J, Wiese-Bjornstal DM. Ice Hockey Summit II: zero tolerance for head hits and fighting. Clin J Sport Med. 2015 Mar; 25(2):78-87. PMID: 25866860.
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    26. Smith AM, Stuart MJ, Dodick DW, Roberts WO, Alford PW, Ashare AB, Aubrey M, Benson BW, Burke CJ, Dick R, Eickhoff C, Emery CA, Flashman LA, Gaz DV, Giza CC, Greenwald RM, Herring SA, Hoshizaki TB, Hudziak JJ, Huston J, Krause D, LaVoi N, Leaf M, Leddy JJ, MacPherson A, McKee AC, Mihalik JP, Moessner AM, Montelpare WJ, Putukian M, Schneider KJ, Szalkowski R, Tabrum M, Whitehead JR, Wiese-Bjornstal DM. Ice Hockey Summit II: zero tolerance for head hits and fighting. Curr Sports Med Rep. 2015 Mar-Apr; 14(2):135-44. PMID: 25757010.
      Citations:    
    27. Smith AM, Stuart MJ, Dodick DW, Roberts WO, Alford PW, Ashare AB, Aubrey M, Benson BW, Burke CJ, Dick R, Eickhoff C, Emery CA, Flashman LA, Gaz DV, Giza CC, Greenwald RM, Herring SA, Hoshizaki TB, Hudziak JJ, Huston J, Krause D, LaVoi N, Leaf M, Leddy JJ, MacPherson A, McKee AC, Mihalik JP, Moessner AM, Montelpare WJ, Putukian M, Schneider KJ, Szalkowski R, Tabrum M, Whitehead JR, Wiese-Bjornstal DM. Ice hockey summit II: zero tolerance for head hits and fighting. PM R. 2015 Mar; 7(3):283-95. PMID: 25797614.
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    28. Ji S, Zhao W, Ford JC, Beckwith JG, Bolander RP, Greenwald RM, Flashman LA, Paulsen KD, McAllister TW. Group-wise evaluation and comparison of white matter fiber strain and maximum principal strain in sports-related concussion. J Neurotrauma. 2015 Apr 01; 32(7):441-54. PMID: 24735430.
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    29. Poulin C, Shiner B, Thompson P, Vepstas L, Young-Xu Y, Goertzel B, Watts B, Flashman L, McAllister T. Predicting the risk of suicide by analyzing the text of clinical notes. PLoS One. 2014; 9(1):e85733. PMID: 24489669.
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    30. Ji S, Ghadyani H, Bolander RP, Beckwith JG, Ford JC, McAllister TW, Flashman LA, Paulsen KD, Ernstrom K, Jain S, Raman R, Zhang L, Greenwald RM. Parametric comparisons of intracranial mechanical responses from three validated finite element models of the human head. Ann Biomed Eng. 2014 Jan; 42(1):11-24. PMID: 24077860.
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    31. McAllister TW, Ford JC, Flashman LA, Maerlender A, Greenwald RM, Beckwith JG, Bolander RP, Tosteson TD, Turco JH, Raman R, Jain S. Effect of head impacts on diffusivity measures in a cohort of collegiate contact sport athletes. Neurology. 2014 Jan 07; 82(1):63-9. PMID: 24336143.
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    32. Wilcox BJ, Beckwith JG, Greenwald RM, Chu JJ, McAllister TW, Flashman LA, Maerlender AC, Duhaime AC, Crisco JJ. Head impact exposure in male and female collegiate ice hockey players. J Biomech. 2014 Jan 03; 47(1):109-14. PMID: 24210478.
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    33. Risacher SL, Wang Y, Wishart HA, Rabin LA, Flashman LA, McDonald BC, West JD, Santulli RB, Saykin AJ. Cholinergic Enhancement of Brain Activation in Mild Cognitive Impairment during Episodic Memory Encoding. Front Psychiatry. 2013; 4:105. PMID: 24062699.
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    34. Bujarski KA, Hirashima F, Roberts DW, Jobst BC, Gilbert KL, Roth RM, Flashman LA, McDonald BC, Saykin AJ, Scott RC, Dinnerstein E, Preston J, Williamson PD, Thadani VM. Long-term seizure, cognitive, and psychiatric outcome following trans-middle temporal gyrus amygdalohippocampectomy and standard temporal lobectomy. J Neurosurg. 2013 Jul; 119(1):16-23. PMID: 23621601.
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    35. Maerlender A, Flashman L, Kessler A, Kumbhani S, Greenwald R, Tosteson T, McAllister T. Discriminant construct validity of ImPACT™: a companion study. Clin Neuropsychol. 2013; 27(2):290-9. PMID: 23317033.
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    36. Risacher SL, Wudunn D, Pepin SM, MaGee TR, McDonald BC, Flashman LA, Wishart HA, Pixley HS, Rabin LA, Paré N, Englert JJ, Schwartz E, Curtain JR, West JD, O'Neill DP, Santulli RB, Newman RW, Saykin AJ. Visual contrast sensitivity in Alzheimer's disease, mild cognitive impairment, and older adults with cognitive complaints. Neurobiol Aging. 2013 Apr; 34(4):1133-44. PMID: 23084085.
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    37. Duhaime AC, Beckwith JG, Maerlender AC, McAllister TW, Crisco JJ, Duma SM, Brolinson PG, Rowson S, Flashman LA, Chu JJ, Greenwald RM. Spectrum of acute clinical characteristics of diagnosed concussions in college athletes wearing instrumented helmets: clinical article. J Neurosurg. 2012 Dec; 117(6):1092-9. PMID: 23030057.
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    38. McAllister TW, Flashman LA, Maerlender A, Greenwald RM, Beckwith JG, Tosteson TD, Crisco JJ, Brolinson PG, Duma SM, Duhaime AC, Grove MR, Turco JH. Cognitive effects of one season of head impacts in a cohort of collegiate contact sport athletes. Neurology. 2012 May 29; 78(22):1777-84. PMID: 22592370.
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    39. McAllister TW, Tyler AL, Flashman LA, Rhodes CH, McDonald BC, Saykin AJ, Tosteson TD, Tsongalis GJ, Moore JH. Polymorphisms in the brain-derived neurotrophic factor gene influence memory and processing speed one month after brain injury. J Neurotrauma. 2012 Apr 10; 29(6):1111-8. PMID: 22188054.
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    40. Magnotta VA, Matsui JT, Liu D, Johnson HJ, Long JD, Bolster BD, Mueller BA, Lim K, Mori S, Helmer KG, Turner JA, Reading S, Lowe MJ, Aylward E, Flashman LA, Bonett G, Paulsen JS. Multicenter reliability of diffusion tensor imaging. Brain Connect. 2012; 2(6):345-55. PMID: 23075313.
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    41. Roth RM, Pixley HS, Kruck CL, Garlinghouse MA, Giancola PR, Flashman LA. Performance on the Cognitive Estimation Test in schizophrenia. Appl Neuropsychol Adult. 2012; 19(2):141-6. PMID: 23373582.
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    42. McAllister TW, Ford JC, Ji S, Beckwith JG, Flashman LA, Paulsen K, Greenwald RM. Maximum principal strain and strain rate associated with concussion diagnosis correlates with changes in corpus callosum white matter indices. Ann Biomed Eng. 2012 Jan; 40(1):127-40. PMID: 21994062.
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    43. Ji S, Ford JC, Greenwald RM, Beckwith JG, Paulsen KD, Flashman LA, McAllister TW. Automated subject-specific, hexahedral mesh generation via image registration. Finite Elem Anal Des. 2011 Oct 01; 47(10):1178-1185. PMID: 21731153.
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    44. Wang Y, West JD, Flashman LA, Wishart HA, Santulli RB, Rabin LA, Pare N, Arfanakis K, Saykin AJ. Selective changes in white matter integrity in MCI and older adults with cognitive complaints. Biochim Biophys Acta. 2012 Mar; 1822(3):423-30. PMID: 21867750.
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    45. McAllister TW, McDonald BC, Flashman LA, Ferrell RB, Tosteson TD, Yanofsky NN, Grove MR, Saykin AJ. Alpha-2 adrenergic challenge with guanfacine one month after mild traumatic brain injury: altered working memory and BOLD response. Int J Psychophysiol. 2011 Oct; 82(1):107-14. PMID: 21767584.
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    46. Kruck CL, Roth RM, Kumbhani SR, Garlinghouse MA, Flashman LA, McAllister TW. Inferential-reasoning impairment in schizophrenia-spectrum disorders. J Neuropsychiatry Clin Neurosci. 2011; 23(2):211-4. PMID: 21677253.
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    47. McAllister TW, Flashman LA, McDonald BC, Ferrell RB, Tosteson TD, Yanofsky NN, Grove MR, Saykin AJ. Dopaminergic challenge with bromocriptine one month after mild traumatic brain injury: altered working memory and BOLD response. J Neuropsychiatry Clin Neurosci. 2011; 23(3):277-86. PMID: 21948888.
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    48. Koven NS, Roth RM, Garlinghouse MA, Flashman LA, Saykin AJ. Regional gray matter correlates of perceived emotional intelligence. Soc Cogn Affect Neurosci. 2011 Oct; 6(5):582-90. PMID: 20934987.
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    49. Maerlender A, Flashman L, Kessler A, Kumbhani S, Greenwald R, Tosteson T, McAllister T. Examination of the construct validity of ImPACT™ computerized test, traditional, and experimental neuropsychological measures. Clin Neuropsychol. 2010 Nov; 24(8):1309-25. PMID: 20924979.
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    50. Sloan CD, Shen L, West JD, Wishart HA, Flashman LA, Rabin LA, Santulli RB, Guerin SJ, Rhodes CH, Tsongalis GJ, McAllister TW, Ahles TA, Lee SL, Moore JH, Saykin AJ. Genetic pathway-based hierarchical clustering analysis of older adults with cognitive complaints and amnestic mild cognitive impairment using clinical and neuroimaging phenotypes. . 2010 Jul; 153B(5):1060-9. PMID: 20468060.
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    51. Garlinghouse MA, Roth RM, Isquith PK, Flashman LA, Saykin AJ. Subjective rating of working memory is associated with frontal lobe volume in schizophrenia. Schizophr Res. 2010 Jul; 120(1-3):71-5. PMID: 20303715.
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    52. Shen L, Saykin AJ, Kim S, Firpi HA, West JD, Risacher SL, McDonald BC, McHugh TL, Wishart HA, Flashman LA. Comparison of manual and automated determination of hippocampal volumes in MCI and early AD. Brain Imaging Behav. 2010 Mar; 4(1):86-95. PMID: 20454594.
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    53. Hurley RA, Flashman LA, Chow TW, Taber KH. The brainstem: anatomy, assessment, and clinical syndromes. J Neuropsychiatry Clin Neurosci. 2010; 22(1):iv, 1-7. PMID: 20160204.
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    54. Kumbhani SR, Roth RM, Kruck CL, Flashman LA, McAllister TW. Nonclinical obsessive-compulsive symptoms and executive functions in schizophrenia. J Neuropsychiatry Clin Neurosci. 2010; 22(3):304-12. PMID: 20686137.
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    55. Kruck CL, Flashman LA, Roth RM, Koven NS, McAllister TW, Saykin AJ. Lack of relationship between psychological denial and unawareness of illness in schizophrenia-spectrum disorders. Psychiatry Res. 2009 Aug 30; 169(1):33-8. PMID: 19616309.
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    56. Rabin LA, Saykin AJ, West JD, Borgos MJ, Wishart HA, Nutter-Upham KE, Flashman LA, Santulli RB. Judgment in Older Adults with Normal Cognition, Cognitive Complaints, MCI, and Mild AD: Relation to Regional Frontal Gray Matter. Brain Imaging Behav. 2009 Jun; 3(2):212-219. PMID: 24741381.
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    57. Rabin LA, Paré N, Saykin AJ, Brown MJ, Wishart HA, Flashman LA, Santulli RB. Differential memory test sensitivity for diagnosing amnestic mild cognitive impairment and predicting conversion to Alzheimer's disease. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2009 May; 16(3):357-76. PMID: 19353345.
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    58. McAllister TW, Flashman LA, Harker Rhodes C, Tyler AL, Moore JH, Saykin AJ, McDonald BC, Tosteson TD, Tsongalis GJ. Single nucleotide polymorphisms in ANKK1 and the dopamine D2 receptor gene affect cognitive outcome shortly after traumatic brain injury: a replication and extension study. Brain Inj. 2008 Aug; 22(9):705-14. PMID: 18698520.
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    59. Nutter-Upham KE, Saykin AJ, Rabin LA, Roth RM, Wishart HA, Pare N, Flashman LA. Verbal fluency performance in amnestic MCI and older adults with cognitive complaints. Arch Clin Neuropsychol. 2008 May; 23(3):229-41. PMID: 18339515.
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    60. Rabin LA, Borgos MJ, Saykin AJ, Wishart HA, Crane PK, Nutter-Upham KE, Flashman LA. Judgment in older adults: development and psychometric evaluation of the Test of Practical Judgment (TOP-J). J Clin Exp Neuropsychol. 2007 Oct; 29(7):752-67. PMID: 17896200.
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    61. Roth RM, Koven NS, Pendergrass JC, Flashman LA, McAllister TW, Saykin AJ. Apathy and the processing of novelty in schizophrenia. Schizophr Res. 2008 Jan; 98(1-3):232-8. PMID: 17884352.
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    62. Roth RM, Flashman LA, McAllister TW. Apathy and its treatment. Curr Treat Options Neurol. 2007 Sep; 9(5):363-70. PMID: 17716600.
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    63. Roth RM, Saykin AJ, Flashman LA, Pixley HS, West JD, Mamourian AC. Event-related functional magnetic resonance imaging of response inhibition in obsessive-compulsive disorder. Biol Psychiatry. 2007 Oct 15; 62(8):901-9. PMID: 17511967.
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    64. Rabin LA, Saykin AJ, Wishart HA, Nutter-Upham KE, Flashman LA, Pare N, Santulli RB. The Memory and Aging Telephone Screen: development and preliminary validation. Alzheimers Dement. 2007 Apr; 3(2):109-21. PMID: 19595923.
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    65. Flashman LA, Roth RM, Pixley HS, Cleavinger HB, McAllister TW, Vidaver R, Saykin AJ. Cavum septum pellucidum in schizophrenia: clinical and neuropsychological correlates. Psychiatry Res. 2007 Feb 28; 154(2):147-55. PMID: 17291728.
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    66. McHugh TL, Saykin AJ, Wishart HA, Flashman LA, Cleavinger HB, Rabin LA, Mamourian AC, Shen L. Hippocampal volume and shape analysis in an older adult population. Clin Neuropsychol. 2007 Jan; 21(1):130-45. PMID: 17366281.
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    67. Wishart HA, Saykin AJ, McAllister TW, Rabin LA, McDonald BC, Flashman LA, Roth RM, Mamourian AC, Tsongalis GJ, Rhodes CH. Regional brain atrophy in cognitively intact adults with a single APOE epsilon4 allele. Neurology. 2006 Oct 10; 67(7):1221-4. PMID: 17030756.
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    68. McAllister TW, Flashman LA, McDonald BC, Saykin AJ. Mechanisms of working memory dysfunction after mild and moderate TBI: evidence from functional MRI and neurogenetics. J Neurotrauma. 2006 Oct; 23(10):1450-67. PMID: 17020482.
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    69. Rabin LA, Roth RM, Isquith PK, Wishart HA, Nutter-Upham KE, Pare N, Flashman LA, Saykin AJ. Self- and informant reports of executive function on the BRIEF-A in MCI and older adults with cognitive complaints. Arch Clin Neuropsychol. 2006 Oct; 21(7):721-32. PMID: 16979868.
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    70. Saykin AJ, Wishart HA, Rabin LA, Santulli RB, Flashman LA, West JD, McHugh TL, Mamourian AC. Older adults with cognitive complaints show brain atrophy similar to that of amnestic MCI. Neurology. 2006 Sep 12; 67(5):834-42. PMID: 16966547.
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    71. Wishart HA, Saykin AJ, Rabin LA, Santulli RB, Flashman LA, Guerin SJ, Mamourian AC, Belloni DR, Rhodes CH, McAllister TW. Increased brain activation during working memory in cognitively intact adults with the APOE epsilon4 allele. Am J Psychiatry. 2006 Sep; 163(9):1603-10. PMID: 16946187.
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    72. Copenhaver BR, Rabin LA, Saykin AJ, Roth RM, Wishart HA, Flashman LA, Santulli RB, McHugh TL, Mamourian AC. The fornix and mammillary bodies in older adults with Alzheimer's disease, mild cognitive impairment, and cognitive complaints: a volumetric MRI study. Psychiatry Res. 2006 Oct 30; 147(2-3):93-103. PMID: 16920336.
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    73. Roth RM, Koven NS, Randolph JJ, Flashman LA, Pixley HS, Ricketts SM, Wishart HA, Saykin AJ. Functional magnetic resonance imaging of executive control in bipolar disorder. Neuroreport. 2006 Jul 31; 17(11):1085-9. PMID: 16837832.
      Citations:    
    74. Marshall RC, McGurk SR, Karow CM, Kairy TJ, Flashman LA. Performance of subjects with and without severe mental illness on a clinical test of problem solving. Schizophr Res. 2006 Jun; 84(2-3):331-44. PMID: 16545542.
      Citations:    
    75. Wang PJ, Saykin AJ, Flashman LA, Wishart HA, Rabin LA, Santulli RB, McHugh TL, MacDonald JW, Mamourian AC. Regionally specific atrophy of the corpus callosum in AD, MCI and cognitive complaints. Neurobiol Aging. 2006 Nov; 27(11):1613-7. PMID: 16271806.
      Citations:    
    76. McAllister TW, Rhodes CH, Flashman LA, McDonald BC, Belloni D, Saykin AJ. Effect of the dopamine D2 receptor T allele on response latency after mild traumatic brain injury. Am J Psychiatry. 2005 Sep; 162(9):1749-51. PMID: 16135640.
      Citations:    
    77. Arciniegas DB, Lauterbach EC, Anderson KE, Chow TW, Flashman LA, Hurley RA, Kaufer DI, McAllister TW, Reeve A, Schiffer RB, Silver JM. The differential diagnosis of pseudobulbar affect (PBA). Distinguishing PBA among disorders of mood and affect. Proceedings of a roundtable meeting. CNS Spectr. 2005 May; 10(5):1-14; quiz 15-6. PMID: 15962457.
      Citations:    
    78. McAllister TW, Ahles TA, Saykin AJ, Ferguson RJ, McDonald BC, Lewis LD, Flashman LA, Rhodes CH. Cognitive effects of cytotoxic cancer chemotherapy: predisposing risk factors and potential treatments. Curr Psychiatry Rep. 2004 Oct; 6(5):364-71. PMID: 15355759.
      Citations:    
    79. Ferrell RB, Wolinsky EJ, Kauffman CI, Flashman LA, McAllister TW. Neuropsychiatric syndromes in adults with intellectual disability: issues in assessment and treatment. Curr Psychiatry Rep. 2004 Oct; 6(5):380-90. PMID: 15355761.
      Citations:    
    80. Saykin AJ, Wishart HA, Rabin LA, Flashman LA, McHugh TL, Mamourian AC, Santulli RB. Cholinergic enhancement of frontal lobe activity in mild cognitive impairment. Brain. 2004 Jul; 127(Pt 7):1574-83. PMID: 15140813.
      Citations:    
    81. McAllister TW, Flashman LA, Sparling MB, Saykin AJ. Working memory deficits after traumatic brain injury: catecholaminergic mechanisms and prospects for treatment -- a review. Brain Inj. 2004 Apr; 18(4):331-50. PMID: 14742148.
      Citations:    
    82. Flashman LA, Green MF. Review of cognition and brain structure in schizophrenia: profiles, longitudinal course, and effects of treatment. Psychiatr Clin North Am. 2004 Mar; 27(1):1-18, vii. PMID: 15062627.
      Citations:    
    83. Monarch ES, Saykin AJ, Flashman LA. Neuropsychological impairment in borderline personality disorder. Psychiatr Clin North Am. 2004 Mar; 27(1):67-82, viii-ix. PMID: 15062631.
      Citations:    
    84. Wishart HA, Saykin AJ, McDonald BC, Mamourian AC, Flashman LA, Schuschu KR, Ryan KA, Fadul CE, Kasper LH. Brain activation patterns associated with working memory in relapsing-remitting MS. Neurology. 2004 Jan 27; 62(2):234-8. PMID: 14745059.
      Citations:    
    85. Roth RM, Flashman LA, Saykin AJ, McAllister TW, Vidaver R. Apathy in schizophrenia: reduced frontal lobe volume and neuropsychological deficits. Am J Psychiatry. 2004 Jan; 161(1):157-9. PMID: 14702265.
      Citations:    
    86. Roth RM, Wishart HA, Flashman LA, Riordan HJ, Huey L, Saykin AJ. Contribution of organizational strategy to verbal learning and memory in adults with attention-deficit/hyperactivity disorder. Neuropsychology. 2004 Jan; 18(1):78-84. PMID: 14744190.
      Citations:    
    87. Davis JD, Stern RA, Flashman LA. Cognitive and neuropsychiatric aspects of subclinical hypothyroidism: significance in the elderly. Curr Psychiatry Rep. 2003 Oct; 5(5):384-90. PMID: 13678560.
      Citations:    
    88. Wishart HA, Roberts DW, Roth RM, McDonald BC, Coffey DJ, Mamourian AC, Hartley C, Flashman LA, Fadul CE, Saykin AJ. Chronic deep brain stimulation for the treatment of tremor in multiple sclerosis: review and case reports. J Neurol Neurosurg Psychiatry. 2003 Oct; 74(10):1392-7. PMID: 14570832.
      Citations:    
    89. Baxter LC, Saykin AJ, Flashman LA, Johnson SC, Guerin SJ, Babcock DR, Wishart HA. Sex differences in semantic language processing: a functional MRI study. Brain Lang. 2003 Feb; 84(2):264-72. PMID: 12590915.
      Citations:    
    90. Flashman LA. Disorders of awareness in neuropsychiatric syndromes: an update. Curr Psychiatry Rep. 2002 Oct; 4(5):346-53. PMID: 12230963.
      Citations:    
    91. Flashman LA, McAllister TW. Lack of awareness and its impact in traumatic brain injury. NeuroRehabilitation. 2002; 17(4):285-96. PMID: 12547977.
      Citations:    
    92. McDonald BC, Flashman LA, Saykin AJ. Executive dysfunction following traumatic brain injury: neural substrates and treatment strategies. NeuroRehabilitation. 2002; 17(4):333-44. PMID: 12547981.
      Citations:    
    93. McAllister TW, Sparling MB, Flashman LA, Saykin AJ. Neuroimaging findings in mild traumatic brain injury. J Clin Exp Neuropsychol. 2001 Dec; 23(6):775-91. PMID: 11910544.
      Citations:    
    94. McAllister TW, Sparling MB, Flashman LA, Guerin SJ, Mamourian AC, Saykin AJ. Differential working memory load effects after mild traumatic brain injury. Neuroimage. 2001 Nov; 14(5):1004-12. PMID: 11697932.
      Citations:    
    95. Roth RM, Flashman LA, Saykin AJ, Roberts DW. Deep brain stimulation in neuropsychiatric disorders. Curr Psychiatry Rep. 2001 Oct; 3(5):366-72. PMID: 11559472.
      Citations:    
    96. Wishart HA, Flashman L, Saykin AJ. The neuropsychology of multiple sclerosis: contributions of neuroimaging research. Curr Psychiatry Rep. 2001 Oct; 3(5):373-8. PMID: 11559473.
      Citations:    
    97. Torres IJ, Flashman LA, O'Leary DS, Andreasen NC. Effects of retroactive and proactive interference on word list recall in schizophrenia. J Int Neuropsychol Soc. 2001 May; 7(4):481-90. PMID: 11396550.
      Citations:    
    98. Flashman LA, McAllister TW, Johnson SC, Rick JH, Green RL, Saykin AJ. Specific frontal lobe subregions correlated with unawareness of illness in schizophrenia: a preliminary study. J Neuropsychiatry Clin Neurosci. 2001; 13(2):255-7. PMID: 11449033.
      Citations:    
    99. Johnson SC, Saykin AJ, Flashman LA, McAllister TW, Sparling MB. Brain activation on fMRI and verbal memory ability: functional neuroanatomic correlates of CVLT performance. J Int Neuropsychol Soc. 2001 Jan; 7(1):55-62. PMID: 11253842.
      Citations:    
    100. Flashman LA, McAllister TW, Andreasen NC, Saykin AJ. Smaller brain size associated with unawareness of illness in patients with schizophrenia. Am J Psychiatry. 2000 Jul; 157(7):1167-9. PMID: 10873930.
      Citations:    
    101. Johnson SC, Saykin AJ, Baxter LC, Flashman LA, Santulli RB, McAllister TW, Mamourian AC. The relationship between fMRI activation and cerebral atrophy: comparison of normal aging and alzheimer disease. Neuroimage. 2000 Mar; 11(3):179-87. PMID: 10694460.
      Citations:    
    102. O'Leary DS, Flaum M, Kesler ML, Flashman LA, Arndt S, Andreasen NC. Cognitive correlates of the negative, disorganized, and psychotic symptom dimensions of schizophrenia. J Neuropsychiatry Clin Neurosci. 2000; 12(1):4-15. PMID: 10678506.
      Citations:    
    103. McAllister TW, Saykin AJ, Flashman LA, Sparling MB, Johnson SC, Guerin SJ, Mamourian AC, Weaver JB, Yanofsky N. Brain activation during working memory 1 month after mild traumatic brain injury: a functional MRI study. Neurology. 1999 Oct 12; 53(6):1300-8. PMID: 10522888.
      Citations:    
    104. Saykin AJ, Johnson SC, Flashman LA, McAllister TW, Sparling M, Darcey TM, Moritz CH, Guerin SJ, Weaver J, Mamourian A. Functional differentiation of medial temporal and frontal regions involved in processing novel and familiar words: an fMRI study. Brain. 1999 Oct; 122 ( Pt 10):1963-71. PMID: 10506097.
      Citations:    
    105. Saykin AJ, Flashman LA, Frutiger SA, Johnson SC, Mamourian AC, Moritz CH, O'Jile JR, Riordan HJ, Santulli RB, Smith CA, Weaver JB. Neuroanatomic substrates of semantic memory impairment in Alzheimer's disease: patterns of functional MRI activation. J Int Neuropsychol Soc. 1999 Jul; 5(5):377-92. PMID: 10439584.
      Citations:    
    106. Riordan HJ, Flashman LA, Saykin AJ, Frutiger SA, Carroll KE, Huey L. Neuropsychological correlates of methylphenidate treatment in adult ADHD with and without depression. Arch Clin Neuropsychol. 1999 Feb; 14(2):217-33. PMID: 14590604.
      Citations:    
    107. Flashman LA, Amador X, McAllister TW. Lack of Awareness of Deficits in Traumatic Brain Injury. Semin Clin Neuropsychiatry. 1998 Jul; 3(3):201-210. PMID: 10085208.
      Citations:    
    108. Nelson MD, Saykin AJ, Flashman LA, Riordan HJ. Hippocampal volume reduction in schizophrenia as assessed by magnetic resonance imaging: a meta-analytic study. Arch Gen Psychiatry. 1998 May; 55(5):433-40. PMID: 9596046.
      Citations:    
    109. Torres IJ, Flashman LA, O'Leary DS, Swayze V, Andreasen NC. Lack of an association between delayed memory and hippocampal and temporal lobe size in patients with schizophrenia and healthy controls. Biol Psychiatry. 1997 Dec 15; 42(12):1087-96. PMID: 9426878.
      Citations:    
    110. Riordan HJ, Flashman LA, Roberts DW. Neurocognitive and psychosocial correlates of ventroposterolateral pallidotomy surgery in Parkinson's disease. Neurosurg Focus. 1997 Mar 15; 2(3):e7. PMID: 15096014.
      Citations:    
    111. O'Leary DS, Andreasen NC, Hurtig RR, Torres IJ, Flashman LA, Kesler ML, Arndt SV, Cizadlo TJ, Ponto LL, Watkins GL, Hichwa RD. Auditory and visual attention assessed with PET. Hum Brain Mapp. 1997; 5(6):422-36. PMID: 20408245.
      Citations:    
    112. Flashman LA, Flaum M, Gupta S, Andreasen NC. Soft signs and neuropsychological performance in schizophrenia. Am J Psychiatry. 1996 Apr; 153(4):526-32. PMID: 8599401.
      Citations:    
    113. Horner MD, Flashman LA, Freides D, Epstein CM, Bakay RA. Temporal lobe epilepsy and performance on the Wisconsin Card Sorting Test. J Clin Exp Neuropsychol. 1996 Apr; 18(2):310-3. PMID: 8780965.
      Citations:    
    114. Andreasen NC, Rajarethinam R, Cizadlo T, Arndt S, Swayze VW, Flashman LA, O'Leary DS, Ehrhardt JC, Yuh WT. Automatic atlas-based volume estimation of human brain regions from MR images. J Comput Assist Tomogr. 1996 Jan-Feb; 20(1):98-106. PMID: 8576490.
      Citations:    
    115. Andreasen NC, Flashman L, Flaum M, Arndt S, Swayze V, O'Leary DS, Ehrhardt JC, Yuh WT. Regional brain abnormalities in schizophrenia measured with magnetic resonance imaging. JAMA. 1994 Dec 14; 272(22):1763-9. PMID: 7966925.
      Citations:    
    116. Nopoulos P, Flashman L, Flaum M, Arndt S, Andreasen N. Stability of cognitive functioning early in the course of schizophrenia. Schizophr Res. 1994 Dec; 14(1):29-37. PMID: 7893619.
      Citations:    
    117. Lewine R, Flashman L, Gulley L, Beardsley S, Wasserman A, Lucas M, Risch SC. Sexual dimorphism in corpus callosum and schizophrenia. Schizophr Res. 1991 Jan-Feb; 4(1):63-4. PMID: 2009256.
      Citations:    
    118. Osborne B, Flashman LA. Meal patterns following changes in procurement cost for rats with fornix transection. Behav Neural Biol. 1986 Sep; 46(2):123-36. PMID: 3767827.
      Citations:    
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