Leslie Poole to Cysteine
This is a "connection" page, showing publications Leslie Poole has written about Cysteine.
Connection Strength
7.482
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Poole LB, Furdui CM, King SB. Introduction to approaches and tools for the evaluation of protein cysteine oxidation. Essays Biochem. 2020 02 17; 64(1):1-17.
Score: 0.648
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Poole LB, Schöneich C. Introduction: What we do and do not know regarding redox processes of thiols in signaling pathways. Free Radic Biol Med. 2015 Mar; 80:145-7.
Score: 0.459
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Poole LB. The basics of thiols and cysteines in redox biology and chemistry. Free Radic Biol Med. 2015 Mar; 80:148-57.
Score: 0.451
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Furdui CM, Poole LB. Chemical approaches to detect and analyze protein sulfenic acids. Mass Spectrom Rev. 2014 Mar-Apr; 33(2):126-46.
Score: 0.415
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Klomsiri C, Karplus PA, Poole LB. Cysteine-based redox switches in enzymes. Antioxid Redox Signal. 2011 Mar 15; 14(6):1065-77.
Score: 0.337
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Hall A, Karplus PA, Poole LB. Typical 2-Cys peroxiredoxins--structures, mechanisms and functions. FEBS J. 2009 May; 276(9):2469-77.
Score: 0.304
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Nelson KJ, Parsonage D, Hall A, Karplus PA, Poole LB. Cysteine pK(a) values for the bacterial peroxiredoxin AhpC. Biochemistry. 2008 Dec 02; 47(48):12860-8.
Score: 0.298
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Poole LB, Nelson KJ. Discovering mechanisms of signaling-mediated cysteine oxidation. Curr Opin Chem Biol. 2008 Feb; 12(1):18-24.
Score: 0.283
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Nelson KJ, Day AE, Zeng BB, King SB, Poole LB. Isotope-coded, iodoacetamide-based reagent to determine individual cysteine pK(a) values by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Anal Biochem. 2008 Apr 15; 375(2):187-95.
Score: 0.278
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Poole LB, Klomsiri C, Knaggs SA, Furdui CM, Nelson KJ, Thomas MJ, Fetrow JS, Daniel LW, King SB. Fluorescent and affinity-based tools to detect cysteine sulfenic acid formation in proteins. Bioconjug Chem. 2007 Nov-Dec; 18(6):2004-17.
Score: 0.277
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Jönsson TJ, Ellis HR, Poole LB. Cysteine reactivity and thiol-disulfide interchange pathways in AhpF and AhpC of the bacterial alkyl hydroperoxide reductase system. Biochemistry. 2007 May 15; 46(19):5709-21.
Score: 0.266
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Poole LB. Bacterial defenses against oxidants: mechanistic features of cysteine-based peroxidases and their flavoprotein reductases. Arch Biochem Biophys. 2005 Jan 01; 433(1):240-54.
Score: 0.227
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Baker LM, Poole LB. Catalytic mechanism of thiol peroxidase from Escherichia coli. Sulfenic acid formation and overoxidation of essential CYS61. J Biol Chem. 2003 Mar 14; 278(11):9203-11.
Score: 0.198
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Poole LB, Ellis HR. Identification of cysteine sulfenic acid in AhpC of alkyl hydroperoxide reductase. Methods Enzymol. 2002; 348:122-36.
Score: 0.185
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Teixeira F, Tse E, Castro H, Makepeace KAT, Meinen BA, Borchers CH, Poole LB, Bardwell JC, Tomás AM, Southworth DR, Jakob U. Chaperone activation and client binding of a 2-cysteine peroxiredoxin. Nat Commun. 2019 02 08; 10(1):659.
Score: 0.151
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Nelson KJ, Bolduc JA, Wu H, Collins JA, Burke EA, Reisz JA, Klomsiri C, Wood ST, Yammani RR, Poole LB, Furdui CM, Loeser RF. H2O2 oxidation of cysteine residues in c-Jun N-terminal kinase 2 (JNK2) contributes to redox regulation in human articular chondrocytes. J Biol Chem. 2018 10 19; 293(42):16376-16389.
Score: 0.147
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Al-Barakati HJ, McConnell EW, Hicks LM, Poole LB, Newman RH, Kc DB. SVM-SulfoSite: A support vector machine based predictor for sulfenylation sites. Sci Rep. 2018 07 26; 8(1):11288.
Score: 0.145
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Portillo-Ledesma S, Randall LM, Parsonage D, Dalla Rizza J, Karplus PA, Poole LB, Denicola A, Ferrer-Sueta G. Differential Kinetics of Two-Cysteine Peroxiredoxin Disulfide Formation Reveal a Novel Model for Peroxide Sensing. Biochemistry. 2018 06 19; 57(24):3416-3424.
Score: 0.142
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Long D, Wu H, Tsang AW, Poole LB, Yoza BK, Wang X, Vachharajani V, Furdui CM, McCall CE. The Oxidative State of Cysteine Thiol 144 Regulates the SIRT6 Glucose Homeostat. Sci Rep. 2017 09 08; 7(1):11005.
Score: 0.137
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Keyes JD, Parsonage D, Yammani RD, Rogers LC, Kesty C, Furdui CM, Nelson KJ, Poole LB. Endogenous, regulatory cysteine sulfenylation of ERK kinases in response to proliferative signals. Free Radic Biol Med. 2017 11; 112:534-543.
Score: 0.136
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Mauney CH, Rogers LC, Harris RS, Daniel LW, Devarie-Baez NO, Wu H, Furdui CM, Poole LB, Perrino FW, Hollis T. The SAMHD1 dNTP Triphosphohydrolase Is Controlled by a Redox Switch. Antioxid Redox Signal. 2017 Dec 01; 27(16):1317-1331.
Score: 0.133
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Nelson KJ, Perkins A, Van Swearingen AED, Hartman S, Brereton AE, Parsonage D, Salsbury FR, Karplus PA, Poole LB. Experimentally Dissecting the Origins of Peroxiredoxin Catalysis. Antioxid Redox Signal. 2018 Mar 01; 28(7):521-536.
Score: 0.133
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Wood ST, Long DL, Reisz JA, Yammani RR, Burke EA, Klomsiri C, Poole LB, Furdui CM, Loeser RF. Cysteine-Mediated Redox Regulation of Cell Signaling in Chondrocytes Stimulated With Fibronectin Fragments. Arthritis Rheumatol. 2016 Jan; 68(1):117-26.
Score: 0.122
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Poole TH, Reisz JA, Zhao W, Poole LB, Furdui CM, King SB. Strained cycloalkynes as new protein sulfenic acid traps. J Am Chem Soc. 2014 Apr 30; 136(17):6167-70.
Score: 0.108
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Klomsiri C, Rogers LC, Soito L, McCauley AK, King SB, Nelson KJ, Poole LB, Daniel LW. Endosomal H2O2 production leads to localized cysteine sulfenic acid formation on proteins during lysophosphatidic acid-mediated cell signaling. Free Radic Biol Med. 2014 Jun; 71:49-60.
Score: 0.108
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Reisz JA, Bechtold E, King SB, Poole LB, Furdui CM. Thiol-blocking electrophiles interfere with labeling and detection of protein sulfenic acids. FEBS J. 2013 Dec; 280(23):6150-61.
Score: 0.104
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Salsbury FR, Poole LB, Fetrow JS. Electrostatics of cysteine residues in proteins: parameterization and validation of a simple model. Proteins. 2012 Nov; 80(11):2583-91.
Score: 0.096
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Crump KE, Juneau DG, Poole LB, Haas KM, Grayson JM. The reversible formation of cysteine sulfenic acid promotes B-cell activation and proliferation. Eur J Immunol. 2012 Aug; 42(8):2152-64.
Score: 0.096
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Qian J, Wani R, Klomsiri C, Poole LB, Tsang AW, Furdui CM. A simple and effective strategy for labeling cysteine sulfenic acid in proteins by utilization of ß-ketoesters as cleavable probes. Chem Commun (Camb). 2012 Apr 28; 48(34):4091-3.
Score: 0.094
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Kaplan N, Urao N, Furuta E, Kim SJ, Razvi M, Nakamura Y, McKinney RD, Poole LB, Fukai T, Ushio-Fukai M. Localized cysteine sulfenic acid formation by vascular endothelial growth factor: role in endothelial cell migration and angiogenesis. Free Radic Res. 2011 Oct; 45(10):1124-35.
Score: 0.089
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Hall A, Nelson K, Poole LB, Karplus PA. Structure-based insights into the catalytic power and conformational dexterity of peroxiredoxins. Antioxid Redox Signal. 2011 Aug 01; 15(3):795-815.
Score: 0.088
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Yuan Y, Knaggs M, Poole L, Fetrow J, Salsbury F. Conformational and oligomeric effects on the cysteine pK(a) of tryparedoxin peroxidase. J Biomol Struct Dyn. 2010 Aug; 28(1):51-70.
Score: 0.084
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Bechtold E, Reisz JA, Klomsiri C, Tsang AW, Wright MW, Poole LB, Furdui CM, King SB. Water-soluble triarylphosphines as biomarkers for protein S-nitrosation. ACS Chem Biol. 2010 Apr 16; 5(4):405-14.
Score: 0.082
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Salsbury FR, Knutson ST, Poole LB, Fetrow JS. Functional site profiling and electrostatic analysis of cysteines modifiable to cysteine sulfenic acid. Protein Sci. 2008 Feb; 17(2):299-312.
Score: 0.070
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Yamamoto Y, Ritz D, Planson AG, Jönsson TJ, Faulkner MJ, Boyd D, Beckwith J, Poole LB. Mutant AhpC peroxiredoxins suppress thiol-disulfide redox deficiencies and acquire deglutathionylating activity. Mol Cell. 2008 Jan 18; 29(1):36-45.
Score: 0.070
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Michalek RD, Nelson KJ, Holbrook BC, Yi JS, Stridiron D, Daniel LW, Fetrow JS, King SB, Poole LB, Grayson JM. The requirement of reversible cysteine sulfenic acid formation for T cell activation and function. J Immunol. 2007 Nov 15; 179(10):6456-67.
Score: 0.069
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Poole LB. The catalytic mechanism of peroxiredoxins. Subcell Biochem. 2007; 44:61-81.
Score: 0.065
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Conway ME, Poole LB, Hutson SM. Roles for cysteine residues in the regulatory CXXC motif of human mitochondrial branched chain aminotransferase enzyme. Biochemistry. 2004 Jun 15; 43(23):7356-64.
Score: 0.055
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Conway ME, Yennawar N, Wallin R, Poole LB, Hutson SM. Human mitochondrial branched chain aminotransferase: structural basis for substrate specificity and role of redox active cysteines. Biochim Biophys Acta. 2003 Apr 11; 1647(1-2):61-5.
Score: 0.050
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Das A, Ash D, Fouda AY, Sudhahar V, Kim YM, Hou Y, Hudson FZ, Stansfield BK, Caldwell RB, McMenamin M, Littlejohn R, Su H, Regan MR, Merrill BJ, Poole LB, Kaplan JH, Fukai T, Ushio-Fukai M. Cysteine oxidation of copper transporter CTR1 drives VEGFR2 signalling and angiogenesis. Nat Cell Biol. 2022 01; 24(1):35-50.
Score: 0.046
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Baker LM, Raudonikiene A, Hoffman PS, Poole LB. Essential thioredoxin-dependent peroxiredoxin system from Helicobacter pylori: genetic and kinetic characterization. J Bacteriol. 2001 Mar; 183(6):1961-73.
Score: 0.044
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Randall LM, Dalla Rizza J, Parsonage D, Santos J, Mehl RA, Lowther WT, Poole LB, Denicola A. Unraveling the effects of peroxiredoxin 2 nitration; role of C-terminal tyrosine 193. Free Radic Biol Med. 2019 09; 141:492-501.
Score: 0.039
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Bolduc JA, Nelson KJ, Haynes AC, Lee J, Reisz JA, Graff AH, Clodfelter JE, Parsonage D, Poole LB, Furdui CM, Lowther WT. Novel hyperoxidation resistance motifs in 2-Cys peroxiredoxins. J Biol Chem. 2018 07 27; 293(30):11901-11912.
Score: 0.036
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Perkins A, Poole LB, Karplus PA. Tuning of peroxiredoxin catalysis for various physiological roles. Biochemistry. 2014 Dec 16; 53(49):7693-705.
Score: 0.028
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Perkins A, Nelson KJ, Williams JR, Parsonage D, Poole LB, Karplus PA. The sensitive balance between the fully folded and locally unfolded conformations of a model peroxiredoxin. Biochemistry. 2013 Dec 03; 52(48):8708-21.
Score: 0.026
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Panmanee W, Vattanaviboon P, Poole LB, Mongkolsuk S. Novel organic hydroperoxide-sensing and responding mechanisms for OhrR, a major bacterial sensor and regulator of organic hydroperoxide stress. J Bacteriol. 2006 Feb; 188(4):1389-95.
Score: 0.015
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Roberts BR, Wood ZA, Jönsson TJ, Poole LB, Karplus PA. Oxidized and synchrotron cleaved structures of the disulfide redox center in the N-terminal domain of Salmonella typhimurium AhpF. Protein Sci. 2005 Sep; 14(9):2414-20.
Score: 0.015
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Jönsson TJ, Murray MS, Johnson LC, Poole LB, Lowther WT. Structural basis for the retroreduction of inactivated peroxiredoxins by human sulfiredoxin. Biochemistry. 2005 Jun 21; 44(24):8634-42.
Score: 0.015
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Wood ZA, Poole LB, Karplus PA. Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling. Science. 2003 Apr 25; 300(5619):650-3.
Score: 0.013