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Khalil Bitar to Animals

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This is a "connection" page, showing publications Khalil Bitar has written about Animals.
Khalil Bitar
Connection Strength
1.522
Animals
  1. Dadhich P, Bohl JL, Tamburrini R, Zakhem E, Scott C, Kock N, Mitchell E, Gilliam J, Bitar KN. BioSphincters to treat Fecal Incontinence in Nonhuman Primates. Sci Rep. 2019 12 02; 9(1):18096.
    View in: PubMed
    Score: 0.067
  2. Bohl JL, Zakhem E, Bitar KN. Successful Treatment of Passive Fecal Incontinence in an Animal Model Using Engineered Biosphincters: A 3-Month Follow-Up Study. Stem Cells Transl Med. 2017 09; 6(9):1795-1802.
    View in: PubMed
    Score: 0.056
  3. Zakhem E, Tamburrini R, Orlando G, Koch KL, Bitar KN. Transplantation of a Human Tissue-Engineered Bowel in an Athymic Rat Model. Tissue Eng Part C Methods. 2017 11; 23(11):652-660.
    View in: PubMed
    Score: 0.056
  4. Zakhem E, El Bahrawy M, Orlando G, Bitar KN. Biomechanical properties of an implanted engineered tubular gut-sphincter complex. J Tissue Eng Regen Med. 2017 12; 11(12):3398-3407.
    View in: PubMed
    Score: 0.054
  5. Bitar KN, Zakhem E. Bioengineering the gut: future prospects of regenerative medicine. Nat Rev Gastroenterol Hepatol. 2016 09; 13(9):543-56.
    View in: PubMed
    Score: 0.053
  6. Zakhem E, Elbahrawy M, Orlando G, Bitar KN. Successful implantation of an engineered tubular neuromuscular tissue composed of human cells and chitosan scaffold. Surgery. 2015 Dec; 158(6):1598-608.
    View in: PubMed
    Score: 0.049
  7. Rego SL, Raghavan S, Zakhem E, Bitar KN. Enteric neural differentiation in innervated, physiologically functional, smooth muscle constructs is modulated by bone morphogenic protein 2 secreted by sphincteric smooth muscle cells. J Tissue Eng Regen Med. 2017 04; 11(4):1251-1261.
    View in: PubMed
    Score: 0.048
  8. Zakhem E, Rego SL, Raghavan S, Bitar KN. The appendix as a viable source of neural progenitor cells to functionally innervate bioengineered gastrointestinal smooth muscle tissues. Stem Cells Transl Med. 2015 Jun; 4(6):548-54.
    View in: PubMed
    Score: 0.048
  9. Bitar KN, Raghavan S. Stem cell therapy for GI neuromuscular disorders. Curr Gastroenterol Rep. 2014 Dec; 16(12):419.
    View in: PubMed
    Score: 0.047
  10. Bitar KN. Regarding "Perianal implantation of bioengineered human internal anal sphincter constructs intrinsically innervated with human neural progenitor cells". Surgery. 2015 Jan; 157(1):178.
    View in: PubMed
    Score: 0.046
  11. Raghavan S, Bitar KN. The influence of extracellular matrix composition on the differentiation of neuronal subtypes in tissue engineered innervated intestinal smooth muscle sheets. Biomaterials. 2014 Aug; 35(26):7429-40.
    View in: PubMed
    Score: 0.046
  12. Bitar KN, Raghavan S, Zakhem E. Tissue engineering in the gut: developments in neuromusculature. Gastroenterology. 2014 Jun; 146(7):1614-24.
    View in: PubMed
    Score: 0.045
  13. Raghavan S, Miyasaka EA, Gilmont RR, Somara S, Teitelbaum DH, Bitar KN. Perianal implantation of bioengineered human internal anal sphincter constructs intrinsically innervated with human neural progenitor cells. Surgery. 2014 Apr; 155(4):668-74.
    View in: PubMed
    Score: 0.044
  14. Zakhem E, Raghavan S, Bitar KN. Neo-innervation of a bioengineered intestinal smooth muscle construct around chitosan scaffold. Biomaterials. 2014 Feb; 35(6):1882-9.
    View in: PubMed
    Score: 0.044
  15. Raghavan S, Gilmont RR, Bitar KN. Neuroglial differentiation of adult enteric neuronal progenitor cells as a function of extracellular matrix composition. Biomaterials. 2013 Sep; 34(28):6649-58.
    View in: PubMed
    Score: 0.042
  16. Bitar KN, Zakhem E. Tissue engineering and regenerative medicine as applied to the gastrointestinal tract. Curr Opin Biotechnol. 2013 Oct; 24(5):909-15.
    View in: PubMed
    Score: 0.042
  17. Zakhem E, Raghavan S, Gilmont RR, Bitar KN. Chitosan-based scaffolds for the support of smooth muscle constructs in intestinal tissue engineering. Biomaterials. 2012 Jun; 33(19):4810-7.
    View in: PubMed
    Score: 0.039
  18. Bitar KN, Raghavan S. Intestinal tissue engineering: current concepts and future vision of regenerative medicine in the gut. Neurogastroenterol Motil. 2012 Jan; 24(1):7-19.
    View in: PubMed
    Score: 0.038
  19. Raghavan S, Gilmont RR, Miyasaka EA, Somara S, Srinivasan S, Teitelbaum DH, Bitar KN. Successful implantation of bioengineered, intrinsically innervated, human internal anal sphincter. Gastroenterology. 2011 Jul; 141(1):310-9.
    View in: PubMed
    Score: 0.037
  20. Somara S, Bashllari D, Gilmont RR, Bitar KN. Real-time dynamic movement of caveolin-1 during smooth muscle contraction of human colon and aged rat colon transfected with caveolin-1 cDNA. Am J Physiol Gastrointest Liver Physiol. 2011 Jun; 300(6):G1022-32.
    View in: PubMed
    Score: 0.036
  21. Raghavan S, Lam MT, Foster LL, Gilmont RR, Somara S, Takayama S, Bitar KN. Bioengineered three-dimensional physiological model of colonic longitudinal smooth muscle in vitro. Tissue Eng Part C Methods. 2010 Oct; 16(5):999-1009.
    View in: PubMed
    Score: 0.035
  22. Somara S, Gilmont RR, Varadarajan S, Bitar KN. Phosphorylated HSP20 modulates the association of thin-filament binding proteins: caldesmon with tropomyosin in colonic smooth muscle. Am J Physiol Gastrointest Liver Physiol. 2010 Nov; 299(5):G1164-76.
    View in: PubMed
    Score: 0.035
  23. Raghavan S, Miyasaka EA, Hashish M, Somara S, Gilmont RR, Teitelbaum DH, Bitar KN. Successful implantation of physiologically functional bioengineered mouse internal anal sphincter. Am J Physiol Gastrointest Liver Physiol. 2010 Aug; 299(2):G430-9.
    View in: PubMed
    Score: 0.035
  24. Somara S, Gilmont R, Bitar KN. Role of thin-filament regulatory proteins in relaxation of colonic smooth muscle contraction. Am J Physiol Gastrointest Liver Physiol. 2009 Nov; 297(5):G958-66.
    View in: PubMed
    Score: 0.033
  25. Somara S, Bitar KN. Direct association of calponin with specific domains of PKC-alpha. Am J Physiol Gastrointest Liver Physiol. 2008 Dec; 295(6):G1246-54.
    View in: PubMed
    Score: 0.031
  26. Gilmont RR, Somara S, Bitar KN. VIP induces PKA-mediated rapid and sustained phosphorylation of HSP20. Biochem Biophys Res Commun. 2008 Oct 31; 375(4):552-6.
    View in: PubMed
    Score: 0.030
  27. Somara S, Gilmont RR, Martens JR, Bitar KN. Ectopic expression of caveolin-1 restores physiological contractile response of aged colonic smooth muscle. Am J Physiol Gastrointest Liver Physiol. 2007 Jul; 293(1):G240-9.
    View in: PubMed
    Score: 0.028
  28. Somara S, Bitar KN. Phosphorylated HSP27 modulates the association of phosphorylated caldesmon with tropomyosin in colonic smooth muscle. Am J Physiol Gastrointest Liver Physiol. 2006 Oct; 291(4):G630-9.
    View in: PubMed
    Score: 0.026
  29. Patil SB, Bitar KN. RhoA- and PKC-alpha-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells. Am J Physiol Gastrointest Liver Physiol. 2006 Jan; 290(1):G83-95.
    View in: PubMed
    Score: 0.025
  30. Pang H, Bitar KN. Direct association of RhoA with specific domains of PKC-alpha. . 2005 Oct; 289(4):C982-93.
    View in: PubMed
    Score: 0.024
  31. Hecker L, Baar K, Dennis RG, Bitar KN. Development of a three-dimensional physiological model of the internal anal sphincter bioengineered in vitro from isolated smooth muscle cells. Am J Physiol Gastrointest Liver Physiol. 2005 Aug; 289(2):G188-96.
    View in: PubMed
    Score: 0.024
  32. Bitar KN, Patil SB. Aging and gastrointestinal smooth muscle. Mech Ageing Dev. 2004 Dec; 125(12):907-10.
    View in: PubMed
    Score: 0.024
  33. Somara S, Pang H, Bitar KN. Agonist-induced association of tropomyosin with protein kinase Calpha in colonic smooth muscle. Am J Physiol Gastrointest Liver Physiol. 2005 Feb; 288(2):G268-76.
    View in: PubMed
    Score: 0.023
  34. Patil SB, Tsunoda Y, Pawar MD, Bitar KN. Translocation and association of ROCK-II with RhoA and HSP27 during contraction of rabbit colon smooth muscle cells. Biochem Biophys Res Commun. 2004 Jun 18; 319(1):95-102.
    View in: PubMed
    Score: 0.023
  35. Somara S, Bitar KN. Tropomyosin interacts with phosphorylated HSP27 in agonist-induced contraction of smooth muscle. . 2004 Jun; 286(6):C1290-301.
    View in: PubMed
    Score: 0.022
  36. Patil SB, Pawar MD, Bitar KN. Direct association and translocation of PKC-alpha with calponin. Am J Physiol Gastrointest Liver Physiol. 2004 Jun; 286(6):G954-63.
    View in: PubMed
    Score: 0.022
  37. Patil SB, Pawar MD, Bitar KN. Phosphorylated HSP27 essential for acetylcholine-induced association of RhoA with PKCalpha. Am J Physiol Gastrointest Liver Physiol. 2004 Apr; 286(4):G635-44.
    View in: PubMed
    Score: 0.022
  38. Bitar KN. Aging and neural control of the GI tract: V. Aging and gastrointestinal smooth muscle: from signal transduction to contractile proteins. Am J Physiol Gastrointest Liver Physiol. 2003 Jan; 284(1):G1-7.
    View in: PubMed
    Score: 0.021
  39. Bitar KN. HSP27 phosphorylation and interaction with actin-myosin in smooth muscle contraction. Am J Physiol Gastrointest Liver Physiol. 2002 May; 282(5):G894-903.
    View in: PubMed
    Score: 0.020
  40. Koch KL, Bitar KN, Fortunato JE. Tissue engineering for neuromuscular disorders of the gastrointestinal tract. World J Gastroenterol. 2012 Dec 21; 18(47):6918-25.
    View in: PubMed
    Score: 0.010
  41. Orlando G, Wood KJ, De Coppi P, Baptista PM, Binder KW, Bitar KN, Breuer C, Burnett L, Christ G, Farney A, Figliuzzi M, Holmes JH, Koch K, Macchiarini P, Mirmalek Sani SH, Opara E, Remuzzi A, Rogers J, Saul JM, Seliktar D, Shapira-Schweitzer K, Smith T, Solomon D, Van Dyke M, Yoo JJ, Zhang Y, Atala A, Stratta RJ, Soker S. Regenerative medicine as applied to general surgery. Ann Surg. 2012 May; 255(5):867-80.
    View in: PubMed
    Score: 0.010
  42. Koga H, Sun X, Yang H, Nose K, Somara S, Bitar KN, Owyang C, Okawada M, Teitelbaum DH. Distraction-induced intestinal enterogenesis: preservation of intestinal function and lengthening after reimplantation into normal jejunum. Ann Surg. 2012 Feb; 255(2):302-10.
    View in: PubMed
    Score: 0.010
  43. Miyasaka EA, Raghavan S, Gilmont RR, Mittal K, Somara S, Bitar KN, Teitelbaum DH. In vivo growth of a bioengineered internal anal sphincter: comparison of growth factors for optimization of growth and survival. Pediatr Surg Int. 2011 Feb; 27(2):137-43.
    View in: PubMed
    Score: 0.009
  44. Hashish M, Raghavan S, Somara S, Gilmont RR, Miyasaka E, Bitar KN, Teitelbaum DH. Surgical implantation of a bioengineered internal anal sphincter. J Pediatr Surg. 2010 Jan; 45(1):52-8.
    View in: PubMed
    Score: 0.008
  45. Deng H, Hershenson MB, Lei J, Bitar KN, Fingar DC, Solway J, Bentley JK. p70 Ribosomal S6 kinase is required for airway smooth muscle cell size enlargement but not increased contractile protein expression. Am J Respir Cell Mol Biol. 2010 Jun; 42(6):744-52.
    View in: PubMed
    Score: 0.008
  46. Bentley JK, Deng H, Linn MJ, Lei J, Dokshin GA, Fingar DC, Bitar KN, Henderson WR, Hershenson MB. Airway smooth muscle hyperplasia and hypertrophy correlate with glycogen synthase kinase-3(beta) phosphorylation in a mouse model of asthma. . 2009 Feb; 296(2):L176-84.
    View in: PubMed
    Score: 0.008
  47. Deng H, Dokshin GA, Lei J, Goldsmith AM, Bitar KN, Fingar DC, Hershenson MB, Bentley JK. Inhibition of glycogen synthase kinase-3beta is sufficient for airway smooth muscle hypertrophy. J Biol Chem. 2008 Apr 11; 283(15):10198-207.
    View in: PubMed
    Score: 0.007
  48. Xin X, Hou YT, Li L, Schmiedlin-Ren P, Christman GM, Cheng HL, Bitar KN, Zimmermann EM. IGF-I increases IGFBP-5 and collagen alpha1(I) mRNAs by the MAPK pathway in rat intestinal smooth muscle cells. Am J Physiol Gastrointest Liver Physiol. 2004 May; 286(5):G777-83.
    View in: PubMed
    Score: 0.006
  49. Cao W, Sohn UD, Bitar KN, Behar J, Biancani P, Harnett KM. MAPK mediates PKC-dependent contraction of cat esophageal and lower esophageal sphincter circular smooth muscle. Am J Physiol Gastrointest Liver Physiol. 2003 Jul; 285(1):G86-95.
    View in: PubMed
    Score: 0.005
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