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Connection

John Parks to Cholesterol

This is a "connection" page, showing publications John Parks has written about Cholesterol.
Connection Strength

6.127
  1. Bashore AC, Liu M, Key CC, Boudyguina E, Wang X, Carroll CM, Sawyer JK, Mullick AE, Lee RG, Macauley SL, Parks JS. Targeted Deletion of Hepatocyte Abca1 Increases Plasma HDL (High-Density Lipoprotein) Reverse Cholesterol Transport via the LDL (Low-Density Lipoprotein) Receptor. Arterioscler Thromb Vasc Biol. 2019 09; 39(9):1747-1761.
    View in: PubMed
    Score: 0.593
  2. Key CC, Liu M, Kurtz CL, Chung S, Boudyguina E, Dinh TA, Bashore A, Phelan PE, Freedman BI, Osborne TF, Zhu X, Ma L, Sethupathy P, Biddinger SB, Parks JS. Hepatocyte ABCA1 Deletion Impairs Liver Insulin Signaling and Lipogenesis. Cell Rep. 2017 06 06; 19(10):2116-2129.
    View in: PubMed
    Score: 0.517
  3. Bi X, Zhu X, Gao C, Shewale S, Cao Q, Liu M, Boudyguina E, Gebre AK, Wilson MD, Brown AL, Parks JS. Myeloid cell-specific ATP-binding cassette transporter A1 deletion has minimal impact on atherogenesis in atherogenic diet-fed low-density lipoprotein receptor knockout mice. Arterioscler Thromb Vasc Biol. 2014 Sep; 34(9):1888-99.
    View in: PubMed
    Score: 0.418
  4. Bi X, Zhu X, Duong M, Boudyguina EY, Wilson MD, Gebre AK, Parks JS. Liver ABCA1 deletion in LDLrKO mice does not impair macrophage reverse cholesterol transport or exacerbate atherogenesis. Arterioscler Thromb Vasc Biol. 2013 Oct; 33(10):2288-96.
    View in: PubMed
    Score: 0.393
  5. Zhu X, Parks JS. New roles of HDL in inflammation and hematopoiesis. Annu Rev Nutr. 2012 Aug 21; 32:161-82.
    View in: PubMed
    Score: 0.362
  6. Fessler MB, Parks JS. Intracellular lipid flux and membrane microdomains as organizing principles in inflammatory cell signaling. J Immunol. 2011 Aug 15; 187(4):1529-35.
    View in: PubMed
    Score: 0.345
  7. Zhu X, Owen JS, Wilson MD, Li H, Griffiths GL, Thomas MJ, Hiltbold EM, Fessler MB, Parks JS. Macrophage ABCA1 reduces MyD88-dependent Toll-like receptor trafficking to lipid rafts by reduction of lipid raft cholesterol. J Lipid Res. 2010 Nov; 51(11):3196-206.
    View in: PubMed
    Score: 0.321
  8. Zhu X, Lee JY, Timmins JM, Brown JM, Boudyguina E, Mulya A, Gebre AK, Willingham MC, Hiltbold EM, Mishra N, Maeda N, Parks JS. Increased cellular free cholesterol in macrophage-specific Abca1 knock-out mice enhances pro-inflammatory response of macrophages. J Biol Chem. 2008 Aug 22; 283(34):22930-41.
    View in: PubMed
    Score: 0.277
  9. Xian X, Ding Y, Dieckmann M, Zhou L, Plattner F, Liu M, Parks JS, Hammer RE, Boucher P, Tsai S, Herz J. LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis. Elife. 2017 11 16; 6.
    View in: PubMed
    Score: 0.133
  10. Omar I, Rom O, Aviram M, Cohen-Daniel L, Gebre AK, Parks JS, Berger M. Slfn2 mutation-induced loss of T-cell quiescence leads to elevated de novo sterol synthesis. Immunology. 2017 11; 152(3):484-493.
    View in: PubMed
    Score: 0.131
  11. Shewale SV, Brown AL, Bi X, Boudyguina E, Sawyer JK, Alexander-Miller MA, Parks JS. In vivo activation of leukocyte GPR120/FFAR4 by PUFAs has minimal impact on atherosclerosis in LDL receptor knockout mice. J Lipid Res. 2017 01; 58(1):236-246.
    View in: PubMed
    Score: 0.124
  12. Westerterp M, Tsuchiya K, Tattersall IW, Fotakis P, Bochem AE, Molusky MM, Ntonga V, Abramowicz S, Parks JS, Welch CL, Kitajewski J, Accili D, Tall AR. Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Endothelial Cells Accelerates Atherosclerosis in Mice. Arterioscler Thromb Vasc Biol. 2016 07; 36(7):1328-37.
    View in: PubMed
    Score: 0.120
  13. Ding J, Reynolds LM, Zeller T, Müller C, Lohman K, Nicklas BJ, Kritchevsky SB, Huang Z, de la Fuente A, Soranzo N, Settlage RE, Chuang CC, Howard T, Xu N, Goodarzi MO, Chen YD, Rotter JI, Siscovick DS, Parks JS, Murphy S, Jacobs DR, Post W, Tracy RP, Wild PS, Blankenberg S, Hoeschele I, Herrington D, McCall CE, Liu Y. Alterations of a Cellular Cholesterol Metabolism Network Are a Molecular Feature of Obesity-Related Type 2 Diabetes and Cardiovascular Disease. Diabetes. 2015 Oct; 64(10):3464-74.
    View in: PubMed
    Score: 0.113
  14. Cao Q, Rong S, Repa JJ, St Clair R, Parks JS, Mishra N. Histone deacetylase 9 represses cholesterol efflux and alternatively activated macrophages in atherosclerosis development. Arterioscler Thromb Vasc Biol. 2014 Sep; 34(9):1871-9.
    View in: PubMed
    Score: 0.106
  15. Chung S, Cuffe H, Marshall SM, McDaniel AL, Ha JH, Kavanagh K, Hong C, Tontonoz P, Temel RE, Parks JS. Dietary cholesterol promotes adipocyte hypertrophy and adipose tissue inflammation in visceral, but not in subcutaneous, fat in monkeys. Arterioscler Thromb Vasc Biol. 2014 Sep; 34(9):1880-7.
    View in: PubMed
    Score: 0.105
  16. Zhu X, Chung S, Bi X, Chuang CC, Brown AL, Liu M, Seo J, Cuffe H, Gebre AK, Boudyguina E, Parks JS. Myeloid cell-specific ABCA1 deletion does not worsen insulin resistance in HF diet-induced or genetically obese mouse models. J Lipid Res. 2013 Oct; 54(10):2708-17.
    View in: PubMed
    Score: 0.099
  17. Cheng HY, Wu R, Gebre AK, Hanna RN, Smith DJ, Parks JS, Ley K, Hedrick CC. Increased cholesterol content in gammadelta (?d) T lymphocytes differentially regulates their activation. PLoS One. 2013; 8(5):e63746.
    View in: PubMed
    Score: 0.098
  18. Sene A, Khan AA, Cox D, Nakamura RE, Santeford A, Kim BM, Sidhu R, Onken MD, Harbour JW, Hagbi-Levi S, Chowers I, Edwards PA, Baldan A, Parks JS, Ory DS, Apte RS. Impaired cholesterol efflux in senescent macrophages promotes age-related macular degeneration. Cell Metab. 2013 Apr 02; 17(4):549-61.
    View in: PubMed
    Score: 0.097
  19. Sag D, Wingender G, Nowyhed H, Wu R, Gebre AK, Parks JS, Kronenberg M, Hedrick CC. ATP-binding cassette transporter G1 intrinsically regulates invariant NKT cell development. J Immunol. 2012 Dec 01; 189(11):5129-38.
    View in: PubMed
    Score: 0.094
  20. Parks JS, Crouse JR. Reduction of cholesterol absorption by dietary oleinate and fish oil in African green monkeys. J Lipid Res. 1992 Apr; 33(4):559-68.
    View in: PubMed
    Score: 0.090
  21. Forrest LM, Boudyguina E, Wilson MD, Parks JS. Echium oil reduces atherosclerosis in apoB100-only LDLrKO mice. Atherosclerosis. 2012 Jan; 220(1):118-21.
    View in: PubMed
    Score: 0.088
  22. Chung S, Sawyer JK, Gebre AK, Maeda N, Parks JS. Adipose tissue ATP binding cassette transporter A1 contributes to high-density lipoprotein biogenesis in vivo. Circulation. 2011 Oct 11; 124(15):1663-72.
    View in: PubMed
    Score: 0.087
  23. Smoak KA, Aloor JJ, Madenspacher J, Merrick BA, Collins JB, Zhu X, Cavigiolio G, Oda MN, Parks JS, Fessler MB. Myeloid differentiation primary response protein 88 couples reverse cholesterol transport to inflammation. Cell Metab. 2010 Jun 09; 11(6):493-502.
    View in: PubMed
    Score: 0.080
  24. Sturek JM, Castle JD, Trace AP, Page LC, Castle AM, Evans-Molina C, Parks JS, Mirmira RG, Hedrick CC. An intracellular role for ABCG1-mediated cholesterol transport in the regulated secretory pathway of mouse pancreatic beta cells. J Clin Invest. 2010 Jul; 120(7):2575-89.
    View in: PubMed
    Score: 0.080
  25. Armstrong AJ, Gebre AK, Parks JS, Hedrick CC. ATP-binding cassette transporter G1 negatively regulates thymocyte and peripheral lymphocyte proliferation. J Immunol. 2010 Jan 01; 184(1):173-83.
    View in: PubMed
    Score: 0.077
  26. Karasinska JM, Rinninger F, Lütjohann D, Ruddle P, Franciosi S, Kruit JK, Singaraja RR, Hirsch-Reinshagen V, Fan J, Brunham LR, Bissada N, Ramakrishnan R, Wellington CL, Parks JS, Hayden MR. Specific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function. J Neurosci. 2009 Mar 18; 29(11):3579-89.
    View in: PubMed
    Score: 0.073
  27. Parks JS, Pelkey SJ, Babiak J, Clarkson TB. Contraceptive steroid effects on lipids and lipoproteins in cynomolgus monkeys. Arteriosclerosis. 1989 Mar-Apr; 9(2):261-8.
    View in: PubMed
    Score: 0.073
  28. Hirsch-Reinshagen V, Donkin J, Stukas S, Chan J, Wilkinson A, Fan J, Parks JS, Kuivenhoven JA, Lütjohann D, Pritchard H, Wellington CL. LCAT synthesized by primary astrocytes esterifies cholesterol on glia-derived lipoproteins. J Lipid Res. 2009 May; 50(5):885-93.
    View in: PubMed
    Score: 0.072
  29. Lee RG, Kelley KL, Sawyer JK, Farese RV, Parks JS, Rudel LL. Plasma cholesteryl esters provided by lecithin:cholesterol acyltransferase and acyl-coenzyme a:cholesterol acyltransferase 2 have opposite atherosclerotic potential. Circ Res. 2004 Nov 12; 95(10):998-1004.
    View in: PubMed
    Score: 0.054
  30. Temel RE, Gebre AK, Parks JS, Rudel LL. Compared with Acyl-CoA:cholesterol O-acyltransferase (ACAT) 1 and lecithin:cholesterol acyltransferase, ACAT2 displays the greatest capacity to differentiate cholesterol from sitosterol. J Biol Chem. 2003 Nov 28; 278(48):47594-601.
    View in: PubMed
    Score: 0.050
  31. Dawson PA, Haywood J, Craddock AL, Wilson M, Tietjen M, Kluckman K, Maeda N, Parks JS. Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice. J Biol Chem. 2003 Sep 05; 278(36):33920-7.
    View in: PubMed
    Score: 0.049
  32. Pei Y, Balogun O, Otieno D, Parks JS, Kang HW. The effects of brewers' spent grain on high-fat diet-induced fatty liver. Biochem Biophys Res Commun. 2022 Aug 06; 616:49-55.
    View in: PubMed
    Score: 0.045
  33. Furbee JW, Francone O, Parks JS. In vivo contribution of LCAT to apolipoprotein B lipoprotein cholesteryl esters in LDL receptor and apolipoprotein E knockout mice. J Lipid Res. 2002 Mar; 43(3):428-37.
    View in: PubMed
    Score: 0.045
  34. Huggins KW, Colvin PL, Burleson ER, Kelley K, Sawyer JK, Barrett PH, Rudel LL, Parks JS. Dietary n-3 polyunsaturated fat increases the fractional catabolic rate of medium-sized HDL particles in African green monkeys. J Lipid Res. 2001 Sep; 42(9):1457-66.
    View in: PubMed
    Score: 0.043
  35. Parks JS, Lehner ND, St Clair RW, Lofland HB. Portacaval shunt and whole-body cholesterol metabolism in the cholesterol-fed African green monkey. . 1979 Sep; 161(4):502-7.
    View in: PubMed
    Score: 0.038
  36. Parks JS, Gebre AK, Furbee JW. Lecithin-cholesterol acyltransferase. Assay of cholesterol esterification and phospholipase A2 activities. Methods Mol Biol. 1999; 109:123-31.
    View in: PubMed
    Score: 0.036
  37. Rudel LL, Parks JS, Hedrick CC, Thomas M, Williford K. Lipoprotein and cholesterol metabolism in diet-induced coronary artery atherosclerosis in primates. Role of cholesterol and fatty acids. Prog Lipid Res. 1998 Dec; 37(6):353-70.
    View in: PubMed
    Score: 0.036
  38. He H, Holl K, DeBehnke S, Yeo CT, Hansen P, Gebre AK, Leone-Kabler S, Ruas M, Parks JS, Parrington J, Solberg Woods LC. Tpcn2 knockout mice have improved insulin sensitivity and are protected against high-fat diet-induced weight gain. Physiol Genomics. 2018 08 01; 50(8):605-614.
    View in: PubMed
    Score: 0.034
  39. Parks JS, Lehner ND, St Clair RW, Lofland HB. Whole-body cholesterol metabolism in cholesterol-fed African green monkeys with a variable hypercholesterolemic response. J Lab Clin Med. 1977 Dec; 90(6):1021-34.
    View in: PubMed
    Score: 0.033
  40. Manning JM, Edwards IJ, Wagner WD, Wagner JD, Adams MR, Parks JS. Effects of contraceptive estrogen and progestin on the atherogenic potential of plasma LDLs in cynomolgus monkeys. Arterioscler Thromb Vasc Biol. 1997 Jul; 17(7):1216-23.
    View in: PubMed
    Score: 0.032
  41. Wang J, Gebre AK, Anderson RA, Parks JS. Cloning and in vitro expression of rat lecithin:cholesterol acyltransferase. Biochim Biophys Acta. 1997 Jun 23; 1346(3):207-11.
    View in: PubMed
    Score: 0.032
  42. Miller KR, Parks JS. Influence of vesicle surface composition on the interfacial binding of lecithin:cholesterol acyltransferase and apolipoprotein A-I. J Lipid Res. 1997 Jun; 38(6):1094-102.
    View in: PubMed
    Score: 0.032
  43. Miller KR, Wang J, Sorci-Thomas M, Anderson RA, Parks JS. Glycosylation structure and enzyme activity of lecithin:cholesterol acyltransferase from human plasma, HepG2 cells, and baculoviral and Chinese hamster ovary cell expression systems. J Lipid Res. 1996 Mar; 37(3):551-61.
    View in: PubMed
    Score: 0.030
  44. Wrenn SM, Parks JS, Immermann FW, Rudel LL. ACAT inhibitors CL 283,546 and CL 283,796 reduce LDL cholesterol without affecting cholesterol absorption in African green monkeys. J Lipid Res. 1995 Jun; 36(6):1199-210.
    View in: PubMed
    Score: 0.028
  45. Manning JM, Gebre AK, Edwards IJ, Wagner WD, Rudel LL, Parks JS. Dietary polyunsaturated fat decreases interaction between low density lipoproteins and arterial proteoglycans. Lipids. 1994 Sep; 29(9):635-41.
    View in: PubMed
    Score: 0.027
  46. Ettinger WH, Miller LA, Smith TK, Parks JS. Effect of interleukin-1 alpha on lipoprotein lipids in cynomolgus monkeys: comparison to tumor necrosis factor. Biochim Biophys Acta. 1992 Oct 30; 1128(2-3):186-92.
    View in: PubMed
    Score: 0.023
  47. Sorci-Thomas MG, Owen JS, Fulp B, Bhat S, Zhu X, Parks JS, Shah D, Jerome WG, Gerelus M, Zabalawi M, Thomas MJ. Nascent high density lipoproteins formed by ABCA1 resemble lipid rafts and are structurally organized by three apoA-I monomers. J Lipid Res. 2012 Sep; 53(9):1890-909.
    View in: PubMed
    Score: 0.023
  48. Youm YH, Kanneganti TD, Vandanmagsar B, Zhu X, Ravussin A, Adijiang A, Owen JS, Thomas MJ, Francis J, Parks JS, Dixit VD. The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence. Cell Rep. 2012 Jan 26; 1(1):56-68.
    View in: PubMed
    Score: 0.022
  49. Edwards IJ, Gebre AK, Wagner WD, Parks JS. Reduced proteoglycan binding of low density lipoproteins from monkeys (Macaca fascicularis) fed a fish oil versus lard diet. Arterioscler Thromb. 1991 Nov-Dec; 11(6):1778-85.
    View in: PubMed
    Score: 0.022
  50. Scobey MW, Johnson FL, Parks JS, Rudel LL. Dietary fish oil effects on biliary lipid secretion and cholesterol gallstone formation in the African green monkey. Hepatology. 1991 Oct; 14(4 Pt 1):679-84.
    View in: PubMed
    Score: 0.022
  51. Parks JS, Gebre AK. Studies on the effect of dietary fish oil on the physical and chemical properties of low density lipoproteins in cynomolgus monkeys. J Lipid Res. 1991 Feb; 32(2):305-15.
    View in: PubMed
    Score: 0.021
  52. Parks JS, Kaduck-Sawyer J, Bullock BC, Rudel LL. Effect of dietary fish oil on coronary artery and aortic atherosclerosis in African green monkeys. Arteriosclerosis. 1990 Nov-Dec; 10(6):1102-12.
    View in: PubMed
    Score: 0.020
  53. Auerbach BJ, Parks JS, Applebaum-Bowden D. A rapid and sensitive micro-assay for the enzymatic determination of plasma and lipoprotein cholesterol. J Lipid Res. 1990 Apr; 31(4):738-42.
    View in: PubMed
    Score: 0.020
  54. Whetzel AM, Sturek JM, Nagelin MH, Bolick DT, Gebre AK, Parks JS, Bruce AC, Skaflen MD, Hedrick CC. ABCG1 deficiency in mice promotes endothelial activation and monocyte-endothelial interactions. Arterioscler Thromb Vasc Biol. 2010 Apr; 30(4):809-17.
    View in: PubMed
    Score: 0.019
  55. Maitra U, Parks JS, Li L. An innate immunity signaling process suppresses macrophage ABCA1 expression through IRAK-1-mediated downregulation of retinoic acid receptor alpha and NFATc2. Mol Cell Biol. 2009 Nov; 29(22):5989-97.
    View in: PubMed
    Score: 0.019
  56. Domoki F, Kis B, Gáspár T, Snipes JA, Parks JS, Bari F, Busija DW. Rosuvastatin induces delayed preconditioning against oxygen-glucose deprivation in cultured cortical neurons. . 2009 Jan; 296(1):C97-105.
    View in: PubMed
    Score: 0.018
  57. Chilton FH, Rudel LL, Parks JS, Arm JP, Seeds MC. Mechanisms by which botanical lipids affect inflammatory disorders. Am J Clin Nutr. 2008 Feb; 87(2):498S-503S.
    View in: PubMed
    Score: 0.017
  58. Brunham LR, Kruit JK, Pape TD, Timmins JM, Reuwer AQ, Vasanji Z, Marsh BJ, Rodrigues B, Johnson JD, Parks JS, Verchere CB, Hayden MR. Beta-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment. Nat Med. 2007 Mar; 13(3):340-7.
    View in: PubMed
    Score: 0.016
  59. Singaraja RR, Stahmer B, Brundert M, Merkel M, Heeren J, Bissada N, Kang M, Timmins JM, Ramakrishnan R, Parks JS, Hayden MR, Rinninger F. Hepatic ATP-binding cassette transporter A1 is a key molecule in high-density lipoprotein cholesteryl ester metabolism in mice. Arterioscler Thromb Vasc Biol. 2006 Aug; 26(8):1821-7.
    View in: PubMed
    Score: 0.015
  60. Parks JS, Rudel LL. Different kinetic fates of apolipoproteins A-I and A-II from lymph chylomicra of nonhuman primates. Effect of saturated versus polyunsaturated dietary fat. J Lipid Res. 1982 Mar; 23(3):410-21.
    View in: PubMed
    Score: 0.011
  61. Parks JS, Rudel LL. Isolation and characterization of high density lipoprotein apoproteins in the non-human primate (vervet). J Biol Chem. 1979 Jul 25; 254(14):6716-23.
    View in: PubMed
    Score: 0.009
  62. Ettinger WH, Varma VK, Sorci-Thomas M, Parks JS, Sigmon RC, Smith TK, Verdery RB. Cytokines decrease apolipoprotein accumulation in medium from Hep G2 cells. Arterioscler Thromb. 1994 Jan; 14(1):8-13.
    View in: PubMed
    Score: 0.006
  63. Carr TP, Traber MG, Haines JL, Kayden HJ, Parks JS, Rudel LL. Interrelationships of alpha-tocopherol with plasma lipoproteins in African green monkeys: effects of dietary fats. J Lipid Res. 1993 Nov; 34(11):1863-71.
    View in: PubMed
    Score: 0.006
  64. Adams MR, Kaplan JR, Manuck SB, Koritnik DR, Parks JS, Wolfe MS, Clarkson TB. Inhibition of coronary artery atherosclerosis by 17-beta estradiol in ovariectomized monkeys. Lack of an effect of added progesterone. Arteriosclerosis. 1990 Nov-Dec; 10(6):1051-7.
    View in: PubMed
    Score: 0.005
  65. Crouse JR, Parks JS, Schey HM, Kahl FR. Studies of low density lipoprotein molecular weight in human beings with coronary artery disease. J Lipid Res. 1985 May; 26(5):566-74.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.