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Jamie Justice PhD

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    K01AG059837     (JUSTICE, JAMIE NICOLE)Jul 15, 2018 - Mar 31, 2023
    NIH
    Senescent Cell Burden in Human Aging and Obesity: Functional Consequences and Reduction by Caloric Restriction
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Justice JN, Gubbi S, Kulkarni AS, Bartley JM, Kuchel GA, Barzilai N. A geroscience perspective on immune resilience and infectious diseases: a potential case for metformin. Geroscience. 2020 Sep 09. PMID: 32902818.
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    2. Ahmadi S, Razazan A, Nagpal R, Jain S, Wang B, Mishra SP, Wang S, Justice J, Ding J, McClain DA, Kritchevsky SB, Kitzman D, Yadav H. Metformin Reduces Aging-Related Leaky Gut and Improves Cognitive Function by Beneficially Modulating Gut Microbiome/Goblet Cell/Mucin Axis. J Gerontol A Biol Sci Med Sci. 2020 06 18; 75(7):e9-e21. PMID: 32129462.
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    3. Justice JN, Kritchevsky SB. Putting epigenetic biomarkers to the test for clinical trials. Elife. 2020 06 09; 9. PMID: 32515735.
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    4. Kritchevsky SB, Justice JN. Testing the Geroscience Hypothesis: Early Days. J Gerontol A Biol Sci Med Sci. 2020 01 01; 75(1):99-101. PMID: 31834386.
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    5. De Carvalho FG, Justice JN, Freitas EC, Kershaw EE, Sparks LM. Adipose Tissue Quality in Aging: How Structural and Functional Aspects of Adipose Tissue Impact Skeletal Muscle Quality. Nutrients. 2019 Oct 23; 11(11). PMID: 31652734.
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    6. Carter CS, Justice JN, Thompson L. Lipotoxicity, aging, and muscle contractility: does fiber type matter? Geroscience. 2019 06; 41(3):297-308. PMID: 31227962.
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    7. Justice JN, Nambiar AM, Tchkonia T, LeBrasseur NK, Pascual R, Hashmi SK, Prata L, Masternak MM, Kritchevsky SB, Musi N, Kirkland JL. Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study. EBioMedicine. 2019 Feb; 40:554-563. PMID: 30616998.
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    8. Justice JN, Niedernhofer L, Robbins PD, Aroda VR, Espeland MA, Kritchevsky SB, Kuchel GA, Barzilai N. Development of Clinical Trials to Extend Healthy Lifespan. Cardiovasc Endocrinol Metab. 2018 Dec; 7(4):80-83. PMID: 30906924.
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    9. Justice JN, Ferrucci L, Newman AB, Aroda VR, Bahnson JL, Divers J, Espeland MA, Marcovina S, Pollak MN, Kritchevsky SB, Barzilai N, Kuchel GA. A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup. Geroscience. 2018 12; 40(5-6):419-436. PMID: 30151729.
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    10. Justice JN, Gregory H, Tchkonia T, LeBrasseur NK, Kirkland JL, Kritchevsky SB, Nicklas BJ. Cellular Senescence Biomarker p16INK4a+ Cell Burden in Thigh Adipose is Associated With Poor Physical Function in Older Women. J Gerontol A Biol Sci Med Sci. 2018 06 14; 73(7):939-945. PMID: 28658942.
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    11. Justice JN, Silverstein-Metzler MG, Uberseder B, Appt SE, Clarkson TB, Register TC, Kritchevsky SB, Shively CA. Relationships of depressive behavior and sertraline treatment with walking speed and activity in older female nonhuman primates. Geroscience. 2017 12; 39(5-6):585-600. PMID: 29080976.
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    12. Silverstein-Metzler MG, Justice JN, Appt SE, Groban L, Kitzman DW, Carr JJ, Register TC, Shively CA. Long-term sertraline treatment and depression effects on carotid artery atherosclerosis in premenopausal female primates. Menopause. 2017 Oct; 24(10):1175-1184. PMID: 28609387.
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    13. Stout MB, Justice JN, Nicklas BJ, Kirkland JL. Physiological Aging: Links Among Adipose Tissue Dysfunction, Diabetes, and Frailty. Physiology (Bethesda). 2017 01; 32(1):9-19. PMID: 27927801.
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    14. Shively CA, Silverstein-Metzler M, Justice J, Willard SL. The impact of treatment with selective serotonin reuptake inhibitors on primate cardiovascular disease, behavior, and neuroanatomy. Neurosci Biobehav Rev. 2017 Mar; 74(Pt B):433-443. PMID: 27590831.
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    15. Huffman DM, Justice JN, Stout MB, Kirkland JL, Barzilai N, Austad SN. Evaluating Health Span in Preclinical Models of Aging and Disease: Guidelines, Challenges, and Opportunities for Geroscience. J Gerontol A Biol Sci Med Sci. 2016 11; 71(11):1395-1406. PMID: 27535967.
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    16. Justice J, Miller JD, Newman JC, Hashmi SK, Halter J, Austad SN, Barzilai N, Kirkland JL. Frameworks for Proof-of-Concept Clinical Trials of Interventions That Target Fundamental Aging Processes. J Gerontol A Biol Sci Med Sci. 2016 11; 71(11):1415-1423. PMID: 27535966.
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    17. Justice JN, Cesari M, Seals DR, Shively CA, Carter CS. Comparative Approaches to Understanding the Relation Between Aging and Physical Function. J Gerontol A Biol Sci Med Sci. 2016 10; 71(10):1243-53. PMID: 25910845.
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    18. Seals DR, Justice JN, LaRocca TJ. Physiological geroscience: targeting function to increase healthspan and achieve optimal longevity. J Physiol. 2016 Apr 15; 594(8):2001-24. PMID: 25639909.
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    19. Justice JN, Pierpoint LA, Mani D, Schwartz RS, Enoka RM. Motor function is associated with 1,25(OH)(2)D and indices of insulin-glucose dynamics in non-diabetic older adults. Aging Clin Exp Res. 2014 Jun; 26(3):249-54. PMID: 24155214.
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