Herbert Bonkovsky to 5-Aminolevulinate Synthetase
This is a "connection" page, showing publications Herbert Bonkovsky has written about 5-Aminolevulinate Synthetase.
Connection Strength
2.836
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Tian Q, Li T, Hou W, Zheng J, Schrum LW, Bonkovsky HL. Lon peptidase 1 (LONP1)-dependent breakdown of mitochondrial 5-aminolevulinic acid synthase protein by heme in human liver cells. J Biol Chem. 2011 Jul 29; 286(30):26424-30.
Score: 0.386
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Zheng J, Shan Y, Lambrecht RW, Donohue SE, Bonkovsky HL. Differential regulation of human ALAS1 mRNA and protein levels by heme and cobalt protoporphyrin. Mol Cell Biochem. 2008 Dec; 319(1-2):153-61.
Score: 0.318
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Zheng J, Tian Q, Hou W, Watts JA, Schrum LW, Bonkovsky HL. Tissue-specific expression of ALA synthase-1 and heme oxygenase-1 and their expression in livers of rats chronically exposed to ethanol. FEBS Lett. 2008 Jun 11; 582(13):1829-34.
Score: 0.311
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Kolluri S, Sadlon TJ, May BK, Bonkovsky HL. Haem repression of the housekeeping 5-aminolaevulinic acid synthase gene in the hepatoma cell line LMH. Biochem J. 2005 Nov 15; 392(Pt 1):173-80.
Score: 0.262
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Kolluri S, Elbirt KK, Bonkovsky HL. Heme biosynthesis in a chicken hepatoma cell line (LMH): comparison with primary chick embryo liver cells (CELC). Biochim Biophys Acta. 1999 Nov 16; 1472(3):658-67.
Score: 0.173
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Sardh E, Harper P, Balwani M, Stein P, Rees D, Bissell DM, Desnick R, Parker C, Phillips J, Bonkovsky HL, Vassiliou D, Penz C, Chan-Daniels A, He Q, Querbes W, Fitzgerald K, Kim JB, Garg P, Vaishnaw A, Simon AR, Anderson KE. Phase 1 Trial of an RNA Interference Therapy for Acute Intermittent Porphyria. N Engl J Med. 2019 02 07; 380(6):549-558.
Score: 0.164
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Balwani M, Naik H, Anderson KE, Bissell DM, Bloomer J, Bonkovsky HL, Phillips JD, Overbey JR, Wang B, Singal AK, Liu LU, Desnick RJ. Clinical, Biochemical, and Genetic Characterization of North American Patients With Erythropoietic Protoporphyria and X-linked Protoporphyria. JAMA Dermatol. 2017 08 01; 153(8):789-796.
Score: 0.148
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Cable EE, Gildemeister OS, Pepe JA, Donohue SE, Lambrecht RW, Bonkovsky HL. Hepatic 5-aminolevulinic acid synthase mRNA stability is modulated by inhibitors of heme biosynthesis and by metalloporphyrins. Eur J Biochem. 1996 Aug 15; 240(1):112-7.
Score: 0.138
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Cable EE, Pepe JA, Karamitsios NC, Lambrecht RW, Bonkovsky HL. Differential effects of metalloporphyrins on messenger RNA levels of delta-aminolevulinate synthase and heme oxygenase. Studies in cultured chick embryo liver cells. J Clin Invest. 1994 Aug; 94(2):649-54.
Score: 0.120
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Russo SM, Pepe JA, Cable EE, Lambrecht RW, Bonkovsky HL. Repression of ALA synthase by heme and zinc-mesoporphyrin in a chick embryo liver cell culture model of acute porphyria. Eur J Clin Invest. 1994 Jun; 24(6):406-15.
Score: 0.119
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Cable EE, Cable JW, Bonkovsky HL. Repression of hepatic delta-aminolevulinate synthase by heme and metalloporphyrins: relationship to inhibition of heme oxygenase. Hepatology. 1993 Jul; 18(1):119-27.
Score: 0.111
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Larion S, Caballes FR, Hwang SI, Lee JG, Rossman WE, Parsons J, Steuerwald N, Li T, Maddukuri V, Groseclose G, Finkielstein CV, Bonkovsky HL. Circadian rhythms in acute intermittent porphyria--a pilot study. Eur J Clin Invest. 2013 Jul; 43(7):727-39.
Score: 0.110
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Balwani M, Doheny D, Bishop DF, Nazarenko I, Yasuda M, Dailey HA, Anderson KE, Bissell DM, Bloomer J, Bonkovsky HL, Phillips JD, Liu L, Desnick RJ. Loss-of-function ferrochelatase and gain-of-function erythroid-specific 5-aminolevulinate synthase mutations causing erythropoietic protoporphyria and x-linked protoporphyria in North American patients reveal novel mutations and a high prevalence of X-linked protoporphyria. Mol Med. 2013 Apr 30; 19:26-35.
Score: 0.110
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Cable EE, Healey JF, Greene Y, Evans CO, Bonkovsky HL. Synergistic induction of delta-aminolevulinate synthase by glutethimide and iron: relationship to the synergistic induction of heme oxygenase. Biochim Biophys Acta. 1991 Nov 15; 1080(3):245-51.
Score: 0.099
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Shedlofsky SI, Sinclair PR, Sinclair JF, Bonkovsky HL. Increased glutathione in cultured hepatocytes associated with induction of cytochrome P-450. Lack of effect of glutathione depletion on induction of cytochrome P-450 and delta-aminolevulinate synthase. Biochem Pharmacol. 1984 May 01; 33(9):1487-91.
Score: 0.059
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Phillips J, Farrell C, Wang Y, Singal AK, Anderson K, Balwani M, Bissell M, Bonkovsky H, Seay T, Paw B, Desnick R, Bloomer J. Strong correlation of ferrochelatase enzymatic activity with Mitoferrin-1 mRNA in lymphoblasts of patients with protoporphyria. Mol Genet Metab. 2019 11; 128(3):391-395.
Score: 0.040
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Cable EE, Pepe JA, Donohue SE, Lambrecht RW, Bonkovsky HL. Effects of mifepristone (RU-486) on heme metabolism and cytochromes P-450 in cultured chick embryo liver cells, possible implications for acute porphyria. Eur J Biochem. 1994 Oct 15; 225(2):651-7.
Score: 0.030
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Sinclair PR, Bement WJ, Healey JF, Gorman N, Sinclair JF, Bonkovsky HL, Liem HH, Muller-Eberhard U. Effects of hemopexin on heme-mediated repression of 5-aminolevulinate synthase and induction of heme oxygenase in cultured hepatocytes. Hepatology. 1994 Sep; 20(3):741-6.
Score: 0.030
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Bonkovsky HL, Cable EE, Cable JW, Donohue SE, White EC, Greene YJ, Lambrecht RW, Srivastava KK, Arnold WN. Porphyrogenic properties of the terpenes camphor, pinene, and thujone (with a note on historic implications for absinthe and the illness of Vincent van Gogh). Biochem Pharmacol. 1992 Jun 09; 43(11):2359-68.
Score: 0.026
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Bonkovsky HL. Mechanism of iron potentiation of hepatic uroporphyria: studies in cultured chick embryo liver cells. Hepatology. 1989 Sep; 10(3):354-64.
Score: 0.021
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Bonkovsky HL, Healey JF, Lincoln B, Bacon BR, Bishop DF, Elder GH. Hepatic heme synthesis in a new model of experimental hemochromatosis: studies in rats fed finely divided elemental iron. Hepatology. 1987 Nov-Dec; 7(6):1195-203.
Score: 0.019
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Bonkovsky HL, Lincoln B, Healey JF, Ou LC, Sinclair PR, Muller-Eberhard U. Hepatic heme and drug metabolism in rats with chronic mountain sickness. Am J Physiol. 1986 Oct; 251(4 Pt 1):G467-74.
Score: 0.017
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Sinclair JF, Zaitlin LM, Smith EL, Howell SK, Bonkovsky HL, Sinclair PR. Induction of 5-aminolaevulinate synthase by two- to five-carbon alcohols in cultured chick-embryo hepatocytes. Relationship to induction of cytochrome P-450. Biochem J. 1986 Mar 01; 234(2):405-11.
Score: 0.017
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Sinclair PR, Bement WJ, Bonkovsky HL, Lambrecht RW, Frezza JE, Sinclair JF, Urquhart AJ, Elder GH. Uroporphyrin accumulation produced by halogenated biphenyls in chick-embryo hepatocytes. Reversal of the accumulation by piperonyl butoxide. Biochem J. 1986 Jul 01; 237(1):63-71.
Score: 0.004
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Sinclair PR, Bement WJ, Bonkovsky HL, Sinclair JF. Inhibition of uroporphyrinogen decarboxylase by halogenated biphenyls in chick hepatocyte cultures. Essential role for induction of cytochrome P-448. Biochem J. 1984 Sep 15; 222(3):737-48.
Score: 0.004