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Last Name

Hao Wang, M.D., Ph.D.

TitleAssistant Professor
InstitutionWake Forest School of Medicine
DepartmentAnesthesiology
Address
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    Other Positions
    TitleAssistant Professor
    InstitutionWake Forest School of Medicine
    DepartmentInternal Medicine-Molecular Medicine


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Groban L, Tran QK, Ferrario CM, Sun X, Cheng CP, Kitzman DW, Wang H, Lindsey SH. Female Heart Health: Is GPER the Missing Link? Front Endocrinol (Lausanne). 2019; 10:919. PMID: 31993020.
      View in: PubMed
    2. Yamashita T, Ahmad S, Wright KN, Roberts DJ, VonCannon JL, Wang H, Groban L, Dell'Italia LJ, Ferrario CM. Noncanonical Mechanisms for Direct Bone Marrow Generating Ang II (Angiotensin II) Predominate in CD68 Positive Myeloid Lineage Cells. Hypertension. 2020 Feb; 75(2):500-509. PMID: 31813348.
      View in: PubMed
    3. Ferrario CM, VonCannon J, Ahmad S, Wright KN, Roberts DJ, Wang H, Yamashita T, Groban L, Cheng CP, Collawn JF, Dell'Italia LJ, Varagic J. Activation of the Human Angiotensin-(1-12)-Chymase Pathway in Rats With Human Angiotensinogen Gene Transcripts. Front Cardiovasc Med. 2019; 6:163. PMID: 31803758.
      View in: PubMed
    4. da Silva JS, Sun X, Ahmad S, Wang H, Sudo RT, Varagic J, Ferrario CM, Zapata-Sudo G, Groban L. G-Protein-Coupled Estrogen Receptor Agonist G1 Improves Diastolic Function and Attenuates Cardiac Renin-Angiotensin System Activation in Estrogen-Deficient Hypertensive Rats. J Cardiovasc Pharmacol. 2019 Nov; 74(5):443-452. PMID: 31361702.
      View in: PubMed
    5. Wang H, Sun X, Hodge HS, Ferrario CM, Groban L. NLRP3 inhibition improves heart function in GPER knockout mice. Biochem Biophys Res Commun. 2019 Jun 30; 514(3):998-1003. PMID: 31092335.
      View in: PubMed
    6. Wang H, Sun X, Ahmad S, Su J, Ferrario CM, Groban L. Estrogen modulates the differential expression of cardiac myocyte chymase isoforms and diastolic function. Mol Cell Biochem. 2019 Jun; 456(1-2):85-93. PMID: 30712071.
      View in: PubMed
    7. Alencar AKN, Montes GC, Costa DG, Mendes LVP, Silva AMS, Martinez ST, Trachez MM, Cunha VDMN, Montagnoli TL, Fraga AGM, Wang H, Groban L, Fraga CAM, Sudo RT, Zapata-Sudo G. Cardioprotection Induced by Activation of GPER in Ovariectomized Rats With Pulmonary Hypertension. J Gerontol A Biol Sci Med Sci. 2018 08 10; 73(9):1158-1166. PMID: 29790948.
      View in: PubMed
    8. Wang H, Sun X, Lin MS, Ferrario CM, Van Remmen H, Groban L. G protein-coupled estrogen receptor (GPER) deficiency induces cardiac remodeling through oxidative stress. Transl Res. 2018 09; 199:39-51. PMID: 29758174.
      View in: PubMed
    9. da Silva JS, Gabriel-Costa D, Wang H, Ahmad S, Sun X, Varagic J, Sudo RT, Ferrario CM, Dell Italia LJ, Sudo GZ, Groban L. Blunting of cardioprotective actions of estrogen in female rodent heart linked to altered expression of cardiac tissue chymase and ACE2. J Renin Angiotensin Aldosterone Syst. 2017 Jul-Sep; 18(3):1470320317722270. PMID: 28748720.
      View in: PubMed
    10. da Silva JS, Gabriel-Costa D, Sudo RT, Wang H, Groban L, Ferraz EB, Nascimento JH, Fraga CA, Barreiro EJ, Zapata-Sudo G. Adenosine A2A receptor agonist prevents cardiac remodeling and dysfunction in spontaneously hypertensive male rats after myocardial infarction. Drug Des Devel Ther. 2017; 11:553-562. PMID: 28293100.
      View in: PubMed
    11. Reyes S, Varagic J, Ahmad S, VonCannon J, Kon ND, Wang H, Groban L, Cheng CP, Dell'Italia LJ, Ferrario CM. Novel Cardiac Intracrine Mechanisms Based on Ang-(1-12)/Chymase Axis Require a Revision of Therapeutic Approaches in Human Heart Disease. Curr Hypertens Rep. 2017 Feb; 19(2):16. PMID: 28233239.
      View in: PubMed
    12. Wang H, Sun X, Chou J, Lin M, Ferrario CM, Zapata-Sudo G, Groban L. Inflammatory and mitochondrial gene expression data in GPER-deficient cardiomyocytes from male and female mice. Data Brief. 2017 Feb; 10:465-473. PMID: 28054009.
      View in: PubMed
    13. Alencar AK, Montes GC, Montagnoli T, Silva AM, Martinez ST, Fraga AG, Wang H, Groban L, Sudo RT, Zapata-Sudo G. Activation of GPER ameliorates experimental pulmonary hypertension in male rats. Eur J Pharm Sci. 2017 Jan 15; 97:208-217. PMID: 27836751.
      View in: PubMed
    14. Wang H, Sun X, Chou J, Lin M, Ferrario CM, Zapata-Sudo G, Groban L. Cardiomyocyte-specific deletion of the G protein-coupled estrogen receptor (GPER) leads to left ventricular dysfunction and adverse remodeling: A sex-specific gene profiling analysis. Biochim Biophys Acta Mol Basis Dis. 2017 08; 1863(8):1870-1882. PMID: 27725247.
      View in: PubMed
    15. Wang H, da Silva J, Alencar A, Zapata-Sudo G, Lin MR, Sun X, Ahmad S, Ferrario CM, Groban L. Mast Cell Inhibition Attenuates Cardiac Remodeling and Diastolic Dysfunction in Middle-aged, Ovariectomized Fischer 344 × Brown Norway Rats. J Cardiovasc Pharmacol. 2016 Jul; 68(1):49-57. PMID: 26981683.
      View in: PubMed
    16. Ferrario CM, Ahmad S, Varagic J, Cheng CP, Groban L, Wang H, Collawn JF, Dell Italia LJ. Intracrine angiotensin II functions originate from noncanonical pathways in the human heart. Am J Physiol Heart Circ Physiol. 2016 08 01; 311(2):H404-14. PMID: 27233763.
      View in: PubMed
    17. Wang H, Alencar A, Lin M, Sun X, Sudo RT, Zapata-Sudo G, Lowe DA, Groban L. Activation of GPR30 improves exercise capacity and skeletal muscle strength in senescent female Fischer344 × Brown Norway rats. Biochem Biophys Res Commun. 2016 06 17; 475(1):81-6. PMID: 27173878.
      View in: PubMed
    18. Alencar AK, da Silva JS, Lin M, Silva AM, Sun X, Ferrario CM, Cheng C, Sudo RT, Zapata-Sudo G, Wang H, Groban L. Effect of Age, Estrogen Status, and Late-Life GPER Activation on Cardiac Structure and Function in the Fischer344×Brown Norway Female Rat. J Gerontol A Biol Sci Med Sci. 2017 02; 72(2):152-162. PMID: 27006078.
      View in: PubMed
    19. Nagata S, Varagic J, Kon ND, Wang H, Groban L, Simington SW, Ahmad S, Dell'Italia LJ, VonCannon JL, Deal D, Ferrario CM. Differential expression of the angiotensin-(1-12)/chymase axis in human atrial tissue. Ther Adv Cardiovasc Dis. 2015 Aug; 9(4):168-80. PMID: 26082339.
      View in: PubMed
    20. Wang H, Zhao Z, Lin M, Groban L. Activation of GPR30 inhibits cardiac fibroblast proliferation. Mol Cell Biochem. 2015 Jul; 405(1-2):135-48. PMID: 25893735.
      View in: PubMed
    21. Zhao Z, Wang H, Lin M, Groban L. GPR30 decreases cardiac chymase/angiotensin II by inhibiting local mast cell number. Biochem Biophys Res Commun. 2015 Mar 27; 459(1):131-6. PMID: 25712524.
      View in: PubMed
    22. Wang H, Jessup JA, Zhao Z, Da Silva J, Lin M, MacNamara LM, Ahmad S, Chappell MC, Ferrario CM, Groban L. Characterization of the cardiac renin angiotensin system in oophorectomized and estrogen-replete mRen2.Lewis rats. PLoS One. 2013; 8(10):e76992. PMID: 24204720.
      View in: PubMed
    23. Jessup JA, Wang H, MacNamara LM, Presley TD, Kim-Shapiro DB, Zhang L, Chen AF, Groban L. Estrogen therapy, independent of timing, improves cardiac structure and function in oophorectomized mRen2.Lewis rats. Menopause. 2013 Aug; 20(8):860-8. PMID: 23481117.
      View in: PubMed
    24. Moniwa N, Varagic J, Ahmad S, VonCannon JL, Simington SW, Wang H, Groban L, Brosnihan KB, Nagata S, Kato J, Kitamura K, Gomez RA, Lopez ML, Ferrario CM. Hemodynamic and hormonal changes to dual renin-angiotensin system inhibition in experimental hypertension. Hypertension. 2013 Feb; 61(2):417-24. PMID: 23232645.
      View in: PubMed
    25. Groban L, Wang H, Machado FS, Trask AJ, Kritchevsky SB, Ferrario CM, Diz DI. Low glial angiotensinogen improves body habitus, diastolic function, and exercise tolerance in aging male rats. Cardiovasc Endocrinol. 2012 Sep 01; 1(3):49-58. PMID: 23795309.
      View in: PubMed
    26. Wang H, Jessup JA, Lin MS, Chagas C, Lindsey SH, Groban L. Activation of GPR30 attenuates diastolic dysfunction and left ventricle remodelling in oophorectomized mRen2.Lewis rats. Cardiovasc Res. 2012 Apr 01; 94(1):96-104. PMID: 22328091.
      View in: PubMed
    27. Groban L, Lindsey S, Wang H, Lin MS, Kassik KA, Machado FS, Carter CS. Differential effects of late-life initiation of low-dose enalapril and losartan on diastolic function in senescent Fischer 344 x Brown Norway male rats. Age (Dordr). 2012 Aug; 34(4):831-43. PMID: 21720770.
      View in: PubMed
    28. Jessup JA, Zhang L, Chen AF, Presley TD, Kim-Shapiro DB, Chappell MC, Wang H, Groban L. Neuronal nitric oxide synthase inhibition improves diastolic function and reduces oxidative stress in ovariectomized mRen2.Lewis rats. Menopause. 2011 Jun; 18(6):698-708. PMID: 21293310.
      View in: PubMed
    29. Jessup JA, Zhang L, Presley TD, Kim-Shapiro DB, Wang H, Chen AF, Groban L. Tetrahydrobiopterin restores diastolic function and attenuates superoxide production in ovariectomized mRen2.Lewis rats. Endocrinology. 2011 Jun; 152(6):2428-36. PMID: 21427216.
      View in: PubMed
    30. Jessup JA, Lindsey SH, Wang H, Chappell MC, Groban L. Attenuation of salt-induced cardiac remodeling and diastolic dysfunction by the GPER agonist G-1 in female mRen2.Lewis rats. PLoS One. 2010 Nov 03; 5(11):e15433. PMID: 21082029.
      View in: PubMed
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