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Elaheh Rahbar PhD

TitleAssociate Professor
InstitutionWake Forest School of Medicine
DepartmentBiomedical Engineering
Address
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    K25HL133611     (RAHBAR, ELAHEH)Aug 15, 2017 - Jun 30, 2022
    NIH
    An Integrated Investigation of the Interaction Between PUFAs and Genetic Variants in Trauma and Critical Care
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kirk LM, Waits CMK, Bashore AC, Dosso B, Meyers AK, Renaldo AC, DePalma TJ, Simms KN, Hauser N, Chuang Key CC, McCall CE, Parks JS, Sergeant S, Langefeld CD, Skardal A, Rahbar E. Exploiting three-dimensional human hepatic constructs to investigate the impact of rs174537 on fatty acid metabolism. PLoS One. 2022; 17(1):e0262173. PMID: 35051193.
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    2. Mazzocchi A, Yoo KM, Nairon KG, Kirk LM, Rahbar E, Soker S, Skardal A. Exploiting maleimide-functionalized hyaluronan hydrogels to test cellular responses to physical and biochemical stimuli. Biomed Mater. 2022 Jan 13; 17(2). PMID: 34937006.
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    3. Fasanello DC, Su J, Deng S, Yin R, Colville MJ, Berenson JM, Kelly CM, Freer H, Rollins A, Wagner B, Rivas F, Hall AR, Rahbar E, DeAngelis PL, Paszek MJ, Reesink HL. Hyaluronic acid synthesis, degradation, and crosslinking in equine osteoarthritis: TNF-a-TSG-6-mediated HC-HA formation. Arthritis Res Ther. 2021 08 20; 23(1):218. PMID: 34416923.
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    4. Rahbar E, Cotton BA, Wade CE, Cardenas JC. Acquired antithrombin deficiency is a risk factor for venous thromboembolism after major trauma. Thromb Res. 2021 08; 204:9-12. PMID: 34091120.
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    5. Dosso B, Waits CMK, Simms KN, Sergeant S, Files DC, Howard TD, Langefeld CD, Chilton FH, Rahbar E. Impact of rs174537 on Critically Ill Patients with Acute Lung Injury: A Secondary Analysis of the OMEGA Randomized Clinical Trial. Curr Dev Nutr. 2020 Oct; 4(10):nzaa147. PMID: 33024925.
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    6. Waits CMK, Bower A, Simms KN, Feldman BC, Kim N, Sergeant S, Chilton FH, VandeVord PJ, Langefeld CD, Rahbar E. A Pilot Study Assessing the Impact of rs174537 on Circulating Polyunsaturated Fatty Acids and the Inflammatory Response in Patients with Traumatic Brain Injury. J Neurotrauma. 2020 09 01; 37(17):1880-1891. PMID: 32253986.
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    7. Wei W, Faubel JL, Selvakumar H, Kovari DT, Tsao J, Rivas F, Mohabir AT, Krecker M, Rahbar E, Hall AR, Filler MA, Washburn JL, Weigel PH, Curtis JE. Self-regenerating giant hyaluronan polymer brushes. Nat Commun. 2019 12 04; 10(1):5527. PMID: 31797934.
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    8. Simms K, Rebholz E, Mayberry RM, Basu S, Perlegas A, Guthold M, Kim-Shapiro DB, Rahbar E. Development of Zinc Chelating Resin Polymer Beads for the Removal of Cell-Free Hemoglobin. Ann Biomed Eng. 2019 Jun; 47(6):1470-1478. PMID: 30919138.
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    9. Wajih N, Basu S, Ucer KB, Rigal F, Shakya A, Rahbar E, Vachharajani V, Guthold M, Gladwin MT, Smith LM, Kim-Shapiro DB. Erythrocytic bioactivation of nitrite and its potentiation by far-red light. Redox Biol. 2019 01; 20:442-450. PMID: 30423533.
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    10. Meyer DE, Cotton BA, Fox EE, Stein D, Holcomb JB, Cohen M, Inaba K, Rahbar E. A comparison of resuscitation intensity and critical administration threshold in predicting early mortality among bleeding patients: A multicenter validation in 680 major transfusion patients. J Trauma Acute Care Surg. 2018 10; 85(4):691-696. PMID: 29985236.
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    11. Rahbar E, Waits CMK, Kirby EH, Miller LR, Ainsworth HC, Cui T, Sergeant S, Howard TD, Langefeld CD, Chilton FH. Allele-specific methylation in the FADS genomic region in DNA from human saliva, CD4+ cells, and total leukocytes. Clin Epigenetics. 2018; 10:46. PMID: 29636834.
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    12. Rivas F, Zahid OK, Reesink HL, Peal BT, Nixon AJ, DeAngelis PL, Skardal A, Rahbar E, Hall AR. Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor. Nat Commun. 2018 03 12; 9(1):1037. PMID: 29531292.
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    13. Rahbar E, Ainsworth HC, Howard TD, Hawkins GA, Ruczinski I, Mathias R, Seeds MC, Sergeant S, Hixson JE, Herrington DM, Langefeld CD, Chilton FH. Uncovering the DNA methylation landscape in key regulatory regions within the FADS cluster. PLoS One. 2017; 12(9):e0180903. PMID: 28957329.
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    14. Wajih N, Basu S, Jailwala A, Kim HW, Ostrowski D, Perlegas A, Bolden CA, Buechler NL, Gladwin MT, Caudell DL, Rahbar E, Alexander-Miller MA, Vachharajani V, Kim-Shapiro DB. Potential therapeutic action of nitrite in sickle cell disease. Redox Biol. 2017 08; 12:1026-1039. PMID: 28511346.
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    15. Henriksen HH, Rahbar E, Baer LA, Holcomb JB, Cotton BA, Steinmetz J, Ostrowski SR, Stensballe J, Johansson PI, Wade CE. Pre-hospital transfusion of plasma in hemorrhaging trauma patients independently improves hemostatic competence and acidosis. Scand J Trauma Resusc Emerg Med. 2016 Dec 09; 24(1):145. PMID: 27938373.
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    16. Cui T, Hester AG, Seeds MC, Rahbar E, Howard TD, Sergeant S, Chilton FH. Impact of Genetic and Epigenetic Variations Within the FADS Cluster on the Composition and Metabolism of Polyunsaturated Fatty Acids in Prostate Cancer. Prostate. 2016 09; 76(13):1182-91. PMID: 27197070.
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    17. Liras IN, Rahbar E, Harting MT, Holcomb JB, Cotton BA. When children become adults and adults become most hypercoagulable after trauma: An assessment of admission hypercoagulability by rapid thrombelastography and venous thromboembolic risk. J Trauma Acute Care Surg. 2016 May; 80(5):778-82. PMID: 26886005.
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    18. Choi S, Rahbar MH, Ning J, Del Junco DJ, Rahbar E, Hong C, Piao J, Fox EE, Holcomb JB. Recurrent event frailty models reduced time-varying and other biases in evaluating transfusion protocols for traumatic hemorrhage. J Clin Epidemiol. 2016 09; 77:52-59.e1. PMID: 27134138.
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    19. Sergeant S, Rahbar E, Chilton FH. Gamma-linolenic acid, Dihommo-gamma linolenic, Eicosanoids and Inflammatory Processes. Eur J Pharmacol. 2016 Aug 15; 785:77-86. PMID: 27083549.
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    20. Miller LR, Jorgensen MJ, Kaplan JR, Seeds MC, Rahbar E, Morgan TM, Welborn A, Chilton SM, Gillis J, Hester A, Rukstalis M, Sergeant S, Chilton FH. Alterations in levels and ratios of n-3 and n-6 polyunsaturated fatty acids in the temporal cortex and liver of vervet monkeys from birth to early adulthood. Physiol Behav. 2016 Mar 15; 156:71-8. PMID: 26705667.
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    21. Rahbar E, Cardenas JC, Matijevic N, Del Junco D, Podbielski J, Cohen MJ, Cotton BA, Holcomb JB, Wade CE. Trauma, Time, and Transfusions: A Longitudinal Analysis of Coagulation Markers in Severely Injured Trauma Patients Receiving Modified Whole Blood or Component Blood Products. Shock. 2015 Nov; 44(5):417-25. PMID: 26263433.
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    22. Rahbar MH, Ning J, Choi S, Piao J, Hong C, Huang H, Del Junco DJ, Fox EE, Rahbar E, Holcomb JB. A joint latent class model for classifying severely hemorrhaging trauma patients. BMC Res Notes. 2015 Oct 24; 8:602. PMID: 26498438.
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    23. Ning J, Rahbar MH, Choi S, Hong C, Piao J, del Junco DJ, Fox EE, Rahbar E, Holcomb JB. A joint latent class analysis for adjusting survival bias with application to a trauma transfusion study. Stat Med. 2016 Jan 15; 35(1):65-77. PMID: 26256455.
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    24. Pommerening MJ, Rahbar E, Minei K, Holcomb JB, Wade CE, Schreiber MA, Cohen MJ, Underwood SJ, Nelson M, Cotton BA. Splenectomy is associated with hypercoagulable thrombelastography values and increased risk of thromboembolism. Surgery. 2015 Sep; 158(3):618-26. PMID: 26209572.
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    25. Ning J, Rahbar MH, Choi S, Piao J, Hong C, Del Junco DJ, Rahbar E, Fox EE, Holcomb JB, Wang MC. Estimating the ratio of multivariate recurrent event rates with application to a blood transfusion study. Stat Methods Med Res. 2017 Aug; 26(4):1969-1981. PMID: 26160825.
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    26. Rahbar E, Cardenas JC, Baimukanova G, Usadi B, Bruhn R, Pati S, Ostrowski SR, Johansson PI, Holcomb JB, Wade CE. Endothelial glycocalyx shedding and vascular permeability in severely injured trauma patients. J Transl Med. 2015 Apr 12; 13:117. PMID: 25889764.
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    27. Cardenas JC, Rahbar E, Pommerening MJ, Baer LA, Matijevic N, Cotton BA, Holcomb JB, Wade CE. Measuring thrombin generation as a tool for predicting hemostatic potential and transfusion requirements following trauma. J Trauma Acute Care Surg. 2014 Dec; 77(6):839-45. PMID: 25099452.
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    28. Rahbar E, Akl T, Coté GL, Moore JE, Zawieja DC. Lymph transport in rat mesenteric lymphatics experiencing edemagenic stress. Microcirculation. 2014 Jul; 21(5):359-67. PMID: 24397756.
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    29. Rahbar E, Baer LA, Cotton BA, Holcomb JB, Wade CE. Plasma colloid osmotic pressure is an early indicator of injury and hemorrhagic shock. Shock. 2014 Mar; 41(3):181-7. PMID: 24280690.
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    30. Schwartz DA, Medina M, Cotton BA, Rahbar E, Wade CE, Cohen AM, Beeler AM, Burgess AR, Holcomb JB. Are we delivering two standards of care for pelvic trauma? Availability of angioembolization after hours and on weekends increases time to therapeutic intervention. J Trauma Acute Care Surg. 2014 Jan; 76(1):134-9. PMID: 24368368.
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    31. Rahbar E, Fox EE, del Junco DJ, Harvin JA, Holcomb JB, Wade CE, Schreiber MA, Rahbar MH, Bulger EM, Phelan HA, Brasel KJ, Alarcon LH, Myers JG, Cohen MJ, Muskat P, Cotton BA. Early resuscitation intensity as a surrogate for bleeding severity and early mortality in the PROMMTT study. J Trauma Acute Care Surg. 2013 Jul; 75(1 Suppl 1):S16-23. PMID: 23778506.
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    32. Rahbar E, Weimer J, Gibbs H, Yeh AT, Bertram CD, Davis MJ, Hill MA, Zawieja DC, Moore JE. Passive pressure-diameter relationship and structural composition of rat mesenteric lymphangions. Lymphat Res Biol. 2012 Dec; 10(4):152-63. PMID: 23145980.
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    33. Davis MJ, Rahbar E, Gashev AA, Zawieja DC, Moore JE. Determinants of valve gating in collecting lymphatic vessels from rat mesentery. . 2011 Jul; 301(1):H48-60. PMID: 21460194.
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    34. Rahbar E, Mori D, Moore JE. Three-dimensional analysis of flow disturbances caused by clots in inferior vena cava filters. J Vasc Interv Radiol. 2011 Jun; 22(6):835-42. PMID: 21414805.
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    35. Rahbar E, Moore JE. A model of a radially expanding and contracting lymphangion. J Biomech. 2011 Apr 07; 44(6):1001-7. PMID: 21377158.
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