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Last Name

Christina Elizabeth Hugenschmidt, Ph.D.

TitleAssistant Professor
InstitutionWake Forest School of Medicine
DepartmentInternal Medicine - Gerontology
Address
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    Collapse Research 
    Collapse research activities and funding
    F32DK083214     (HUGENSCHMIDT, CHRISTINA E)Jan 14, 2009 - Jan 13, 2012
    NIH/NIDDK
    Genetic and imaging analysis of cerebrovascular disease and cognition in diabetes
    Role: Principal Investigator

    K01AG043547     (HUGENSCHMIDT, CHRISTINA E)Sep 1, 2013 - May 31, 2018
    NIH/NIA
    Cognitive/Brain Effects of Adding Weight Loss to Exercise in Obese Older Adults
    Role: Principal Investigator

    R01AT009444     (HUGENSCHMIDT, CHRISTINA E)May 1, 2017 - Apr 30, 2020
    NIH/NCCIH
    A randomized trial of dance on mood, balance and brain in Alzheimer's Disease
    Role: Principal Investigator

    R21AG054955     (HUGENSCHMIDT, CHRISTINA E)Jul 15, 2017 - Apr 30, 2019
    NIH/NIA
    The interaction between diabetes and estradiol on human brain metabolism in postmenopausal women
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Nicklas BJ, Brinkley TE, Houston DK, Lyles MF, Hugenschmidt CE, Beavers KM, Leng X. Effects of Caloric Restriction on Cardiorespiratory Fitness, Fatigue, and Disability Responses to Aerobic Exercise in Older Adults With Obesity: A Randomized Controlled Trial. J Gerontol A Biol Sci Med Sci. 2019 Jun 18; 74(7):1084-1090. PMID: 29982294.
      View in: PubMed
    2. Hugenschmidt CE, Leng X, Lyles M, Michael L, Dougherty A, Babcock P, Baker LD, Brinkley TE, Nicklas BJ. Cognitive Effects of Adding Caloric Restriction to Aerobic Exercise Training in Older Adults with Obesity. Obesity (Silver Spring). 2019 Aug; 27(8):1266-1274. PMID: 31199592.
      View in: PubMed
    3. Espeland MA, Carmichael O, Yasar S, Hugenschmidt C, Hazzard W, Hayden KM, Rapp SR, Neiberg R, Johnson KC, Hoscheidt S, Mielke MM. Sex-related differences in the prevalence of cognitive impairment among overweight and obese adults with type 2 diabetes. Alzheimers Dement. 2018 Sep; 14(9):1184-1192. PMID: 30201101.
      View in: PubMed
    4. Hughes TM, Sink KM, Williamson JD, Hugenschmidt CE, Wagner BC, Whitlow CT, Xu J, Smith SC, Launer LJ, Barzilay JI, Ismail-Beigi F, Bryan RN, Hsu FC, Bowden DW, Maldjian JA, Divers J, Freedman BI. Relationships between cerebral structure and cognitive function in African Americans with type 2 diabetes. J Diabetes Complications. 2018 Oct; 32(10):916-921. PMID: 30042057.
      View in: PubMed
    5. Hsu FC, Sink KM, Hugenschmidt CE, Williamson JD, Hughes TM, Palmer ND, Xu J, Smith SC, Wagner BC, Whitlow CT, Bowden DW, Maldjian JA, Divers J, Freedman BI. Cerebral Structure and Cognitive Performance in African Americans and European Americans With Type 2 Diabetes. J Gerontol A Biol Sci Med Sci. 2018 03 02; 73(3):407-414. PMID: 29309525.
      View in: PubMed
    6. Freedman BI, Sink KM, Hugenschmidt CE, Hughes TM, Williamson JD, Whitlow CT, Palmer ND, Miller ME, Lovato LC, Xu J, Smith SC, Launer LJ, Barzilay JI, Cohen RM, Sullivan MD, Bryan RN, Wagner BC, Bowden DW, Maldjian JA, Divers J. Associations of Early Kidney Disease With Brain Magnetic Resonance Imaging and Cognitive Function in African Americans With Type 2 Diabetes Mellitus. Am J Kidney Dis. 2017 Nov; 70(5):627-637. PMID: 28648301.
      View in: PubMed
    7. Palmer Allred ND, Raffield LM, Hardy JC, Hsu FC, Divers J, Xu J, Smith SC, Hugenschmidt CE, Wagner BC, Whitlow CT, Sink KM, Maldjian JA, Williamson JD, Bowden DW, Freedman BI. APOE Genotypes Associate With Cognitive Performance but Not Cerebral Structure: Diabetes Heart Study MIND. Diabetes Care. 2016 Dec; 39(12):2225-2231. PMID: 27703028.
      View in: PubMed
    8. Martelle SE, Raffield LM, Palmer ND, Cox AJ, Freedman BI, Hugenschmidt CE, Williamson JD, Bowden DW. Dopamine pathway gene variants may modulate cognitive performance in the DHS - Mind Study. Brain Behav. 2016 04; 6(4):e00446. PMID: 27066308.
      View in: PubMed
    9. Batson G, Hugenschmidt CE, Soriano CT. Verbal Auditory Cueing of Improvisational Dance: A Proposed Method for Training Agency in Parkinson's Disease. Front Neurol. 2016; 7:15. PMID: 26925029.
      View in: PubMed
    10. Adams JN, Martelle SE, Raffield LM, Freedman BI, Langefeld CD, Hsu FC, Maldjian JA, Williamson JD, Hugenschmidt CE, Carr JJ, Cox AJ, Bowden DW. Analysis of advanced glycation end products in the DHS Mind Study. J Diabetes Complications. 2016 Mar; 30(2):262-8. PMID: 26739237.
      View in: PubMed
    11. Raffield LM, Cox AJ, Freedman BI, Hugenschmidt CE, Hsu FC, Wagner BC, Xu J, Maldjian JA, Bowden DW. Analysis of the relationships between type 2 diabetes status, glycemic control, and neuroimaging measures in the Diabetes Heart Study Mind. Acta Diabetol. 2016 Jun; 53(3):439-47. PMID: 26525870.
      View in: PubMed
    12. Espeland MA, Brinton RD, Hugenschmidt C, Manson JE, Craft S, Yaffe K, Weitlauf J, Vaughan L, Johnson KC, Padula CB, Jackson RD, Resnick SM. Impact of Type 2 Diabetes and Postmenopausal Hormone Therapy on Incidence of Cognitive Impairment in Older Women. Diabetes Care. 2015 Dec; 38(12):2316-24. PMID: 26486190.
      View in: PubMed
    13. Raffield LM, Brenes GA, Cox AJ, Freedman BI, Hugenschmidt CE, Hsu FC, Xu J, Wagner BC, Williamson JD, Maldjian JA, Bowden DW. Associations between anxiety and depression symptoms and cognitive testing and neuroimaging in type 2 diabetes. J Diabetes Complications. 2016 Jan-Feb; 30(1):143-9. PMID: 26476474.
      View in: PubMed
    14. Hugenschmidt CE, Sink KM. No pain, functional gain: the importance of pain management in older adults with cognitive impairment. Pain. 2015 Aug; 156(8):1377-8. PMID: 25993550.
      View in: PubMed
    15. Hsu FC, Raffield LM, Hugenschmidt CE, Cox A, Xu J, Carr JJ, Freedman BI, Maldjian JA, Williamson JD, Bowden DW. Relationships between Cognitive Performance, Neuroimaging and Vascular Disease: The DHS-MIND Study. Neuroepidemiology. 2015; 45(1):1-11. PMID: 26185004.
      View in: PubMed
    16. Espeland MA, Brinton RD, Manson JE, Yaffe K, Hugenschmidt C, Vaughan L, Craft S, Edwards BJ, Casanova R, Masaki K, Resnick SM. Postmenopausal hormone therapy, type 2 diabetes mellitus, and brain volumes. Neurology. 2015 Sep 29; 85(13):1131-8. PMID: 26163429.
      View in: PubMed
    17. Murea M, Hsu FC, Cox AJ, Hugenschmidt CE, Xu J, Adams JN, Raffield LM, Whitlow CT, Maldjian JA, Bowden DW, Freedman BI. Structural and functional assessment of the brain in European Americans with mild-to-moderate kidney disease: Diabetes Heart Study-MIND. Nephrol Dial Transplant. 2015 Aug; 30(8):1322-9. PMID: 25722384.
      View in: PubMed
    18. Raffield LM, Cox AJ, Hugenschmidt CE, Freedman BI, Langefeld CD, Williamson JD, Hsu FC, Maldjian JA, Bowden DW. Heritability and genetic association analysis of neuroimaging measures in the Diabetes Heart Study. Neurobiol Aging. 2015 Mar; 36(3):1602.e7-15. PMID: 25523635.
      View in: PubMed
    19. Palmer ND, Sink KM, Smith SC, Xu J, Bowden DW, Hugenschmidt CE, Whitlow CT, Williamson JD, Maldjian JA, Divers J, Freedman BI. Kidney disease and cognitive function: African American-diabetes heart study MIND. Am J Nephrol. 2014; 40(3):200-7. PMID: 25323981.
      View in: PubMed
    20. Sink KM, Divers J, Whitlow CT, Palmer ND, Smith SC, Xu J, Hugenschmidt CE, Wagner BC, Williamson JD, Bowden DW, Maldjian JA, Freedman BI. Cerebral structural changes in diabetic kidney disease: African American-Diabetes Heart Study MIND. Diabetes Care. 2015 Feb; 38(2):206-12. PMID: 25205141.
      View in: PubMed
    21. Hugenschmidt CE, Lovato JF, Ambrosius WT, Bryan RN, Gerstein HC, Horowitz KR, Launer LJ, Lazar RM, Murray AM, Chew EY, Danis RP, Williamson JD, Miller ME, Ding J. The cross-sectional and longitudinal associations of diabetic retinopathy with cognitive function and brain MRI findings: the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial. Diabetes Care. 2014 Dec; 37(12):3244-52. PMID: 25193529.
      View in: PubMed
    22. Hugenschmidt CE, Burdette JH, Morgan AR, Williamson JD, Kritchevsky SB, Laurienti PJ. Graph theory analysis of functional brain networks and mobility disability in older adults. J Gerontol A Biol Sci Med Sci. 2014 Nov; 69(11):1399-406. PMID: 24717331.
      View in: PubMed
    23. Cox AJ, Hugenschmidt CE, Raffield LM, Langefeld CD, Freedman BI, Williamson JD, Hsu FC, Bowden DW. Heritability and genetic association analysis of cognition in the Diabetes Heart Study. Neurobiol Aging. 2014 Aug; 35(8):1958.e3-1958.e12. PMID: 24684796.
      View in: PubMed
    24. Hugenschmidt CE. A link between type 2 diabetes and brain function. JAAPA. 2013 Dec; 26(12):10-1. PMID: 24213220.
      View in: PubMed
    25. Hugenschmidt C, Williamson JD. Solving the mystery of the diabetes-dementia connection: new clues--but far from "case closed". J Diabetes Complications. 2014 Jan-Feb; 28(1):8-9. PMID: 24268940.
      View in: PubMed
    26. Hugenschmidt CE, Hsu FC, Hayasaka S, Carr JJ, Freedman BI, Nyenhuis DL, Williamson JD, Bowden DW. The influence of subclinical cardiovascular disease and related risk factors on cognition in type 2 diabetes mellitus: The DHS-Mind study. J Diabetes Complications. 2013 Sep-Oct; 27(5):422-8. PMID: 23659774.
      View in: PubMed
    27. Cox AJ, Hugenschmidt CE, Wang PT, Hsu FC, Kenchaiah S, Daniel K, Langefeld CD, Freedman BI, Herrington DM, Carr JJ, Stacey B, Bowden DW. Usefulness of biventricular volume as a predictor of mortality in patients with diabetes mellitus (from the Diabetes Heart Study). Am J Cardiol. 2013 Apr 15; 111(8):1152-8. PMID: 23351459.
      View in: PubMed
    28. Divers J, Hugenschmidt C, Sink KM, Williamson JD, Ge Y, Smith SC, Bowden DW, Whitlow CT, Lyders E, Maldjian JA, Freedman BI. Cerebral white matter hyperintensity in African Americans and European Americans with type 2 diabetes. J Stroke Cerebrovasc Dis. 2013 Oct; 22(7):e46-52. PMID: 22608346.
      View in: PubMed
    29. Moussa MN, Vechlekar CD, Burdette JH, Steen MR, Hugenschmidt CE, Laurienti PJ. Changes in cognitive state alter human functional brain networks. Front Hum Neurosci. 2011; 5:83. PMID: 21991252.
      View in: PubMed
    30. Sergeant S, Hugenschmidt CE, Rudock ME, Ziegler JT, Ivester P, Ainsworth HC, Vaidya D, Case LD, Langefeld CD, Freedman BI, Bowden DW, Mathias RA, Chilton FH. Differences in arachidonic acid levels and fatty acid desaturase (FADS) gene variants in African Americans and European Americans with diabetes or the metabolic syndrome. Br J Nutr. 2012 Feb; 107(4):547-55. PMID: 21733300.
      View in: PubMed
    31. Hayasaka S, Hugenschmidt CE, Laurienti PJ. A network of genes, genetic disorders, and brain areas. PLoS One. 2011; 6(6):e20907. PMID: 21695164.
      View in: PubMed
    32. Mathias RA, Sergeant S, Ruczinski I, Torgerson DG, Hugenschmidt CE, Kubala M, Vaidya D, Suktitipat B, Ziegler JT, Ivester P, Case D, Yanek LR, Freedman BI, Rudock ME, Barnes KC, Langefeld CD, Becker LC, Bowden DW, Becker DM, Chilton FH. The impact of FADS genetic variants on ?6 polyunsaturated fatty acid metabolism in African Americans. BMC Genet. 2011 May 20; 12:50. PMID: 21599946.
      View in: PubMed
    33. Peiffer AM, Hugenschmidt CE, Laurienti PJ. Ethics in 15 min per week. Sci Eng Ethics. 2011 Jun; 17(2):289-97. PMID: 20213534.
      View in: PubMed
    34. Hugenschmidt CE, Hayasaka S, Peiffer AM, Laurienti PJ. Applying capacity analyses to psychophysical evaluation of multisensory interactions. Inf Fusion. 2010 Jan 01; 11(1):12-20. PMID: 20161039.
      View in: PubMed
    35. Hugenschmidt CE, Mozolic JL, Tan H, Kraft RA, Laurienti PJ. Age-related increase in cross-sensory noise in resting and steady-state cerebral perfusion. Brain Topogr. 2009 May; 21(3-4):241-51. PMID: 19415481.
      View in: PubMed
    36. Hugenschmidt CE, Peiffer AM, McCoy TP, Hayasaka S, Laurienti PJ. Preservation of crossmodal selective attention in healthy aging. Exp Brain Res. 2009 Sep; 198(2-3):273-85. PMID: 19404621.
      View in: PubMed
    37. Hugenschmidt CE, Mozolic JL, Laurienti PJ. Suppression of multisensory integration by modality-specific attention in aging. Neuroreport. 2009 Mar 04; 20(4):349-53. PMID: 19218871.
      View in: PubMed
    38. Peiffer AM, Hugenschmidt CE, Maldjian JA, Casanova R, Srikanth R, Hayasaka S, Burdette JH, Kraft RA, Laurienti PJ. Aging and the interaction of sensory cortical function and structure. Hum Brain Mapp. 2009 Jan; 30(1):228-40. PMID: 18072271.
      View in: PubMed
    39. Peiffer AM, Laurienti PJ, Hugenschmidt CE. Fostering a culture of responsible lab conduct. Science. 2008 Nov 21; 322(5905):1186. PMID: 19023060.
      View in: PubMed
    40. Mozolic JL, Joyner D, Hugenschmidt CE, Peiffer AM, Kraft RA, Maldjian JA, Laurienti PJ. Cross-modal deactivations during modality-specific selective attention. BMC Neurol. 2008 Sep 25; 8:35. PMID: 18817554.
      View in: PubMed
    41. Mozolic JL, Hugenschmidt CE, Peiffer AM, Laurienti PJ. Modality-specific selective attention attenuates multisensory integration. Exp Brain Res. 2008 Jan; 184(1):39-52. PMID: 17684735.
      View in: PubMed
    42. Peiffer AM, Mozolic JL, Hugenschmidt CE, Laurienti PJ. Age-related multisensory enhancement in a simple audiovisual detection task. Neuroreport. 2007 Jul 02; 18(10):1077-81. PMID: 17558300.
      View in: PubMed
    43. Hayasaka S, Peiffer AM, Hugenschmidt CE, Laurienti PJ. Power and sample size calculation for neuroimaging studies by non-central random field theory. Neuroimage. 2007 Sep 01; 37(3):721-30. PMID: 17658273.
      View in: PubMed
    44. Hugenschmidt CE, Peiffer AM, Kraft RA, Casanova R, Deibler AR, Burdette JH, Maldjian JA, Laurienti PJ. Relating imaging indices of white matter integrity and volume in healthy older adults. Cereb Cortex. 2008 Feb; 18(2):433-42. PMID: 17575289.
      View in: PubMed
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