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Last Name

Christos Constantinidis, Ph.D.

TitleProfessor
InstitutionWake Forest School of Medicine
DepartmentNeurobiology and Anatomy
Address
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    Collapse Research 
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    R01EY016773     (CONSTANTINIDIS, CHRISTOS)Jun 1, 2005 - Sep 29, 2018
    NIH/NEI
    Cortical Circuit Basis of Visual Spatial Processing
    Role: Principal Investigator

    R01EY017077     (CONSTANTINIDIS, CHRISTOS)Jan 1, 2006 - May 31, 2022
    NIH/NEI
    NEUROPHYSIOLOGICAL EFFECTS OF TRAINING IN VISUAL COGNITIVE TASKS
    Role: Principal Investigator

    R21MH083209     (CONSTANTINIDIS, CHRISTOS)May 1, 2008 - Mar 31, 2011
    NIH/NIMH
    CHOLINERGIC INFLUENCES ON PREFRONTAL CORTICAL ACTIVITY DURING COGNITIVE FUNCTION
    Role: Principal Investigator

    R21MH086946     (CONSTANTINIDIS, CHRISTOS)Sep 22, 2009 - May 31, 2012
    NIH/NIMH
    Neurophysiology of Prefrontal Cortical Development
    Role: Principal Investigator

    R33MH086946     (CONSTANTINIDIS, CHRISTOS)Sep 22, 2009 - May 31, 2014
    NIH/NIMH
    Neurophysiology of Prefrontal Cortical Development
    Role: Principal Investigator

    R01MH097695     (CONSTANTINIDIS, CHRISTOS)Sep 1, 2013 - Jun 30, 2018
    NIH/NIMH
    NEUROMODULATOR INFLUENCES ON PREFRONTAL CORTICAL FUNCTION
    Role: Principal Investigator

    R01MH117996     (CONSTANTINIDIS, CHRISTOS)Jul 25, 2018 - Apr 30, 2023
    NIH/NIMH
    Neurophysiology of cognitive development and response inhibition
    Role: Principal Investigator

    R01MH116675     (CONSTANTINIDIS, CHRISTOS)Aug 28, 2018 - Jun 30, 2023
    NIH/NIMH
    Neurophysiology of Working Memory Maturation in Adolescence
    Role: Principal Investigator

    R01AG060754     (CONSTANTINIDIS, CHRISTOS)Feb 1, 2019 - Dec 31, 2023
    NIH/NIA
    Primate model of deep brain stimulation for Alzheimers and age-related cognitive decline
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Tang H, Qi XL, Riley MR, Constantinidis C. Working memory capacity is enhanced by distributed prefrontal activation and invariant temporal dynamics. Proc Natl Acad Sci U S A. 2019 04 02; 116(14):7095-7100. PMID: 30877250.
      View in: PubMed
    2. Meyers EM, Liang A, Katsuki F, Constantinidis C. Differential Processing of Isolated Object and Multi-item Pop-Out Displays in LIP and PFC. Cereb Cortex. 2018 11 01; 28(11):3816-3828. PMID: 29040434.
      View in: PubMed
    3. Riley MR, Qi XL, Zhou X, Constantinidis C. Anterior-posterior gradient of plasticity in primate prefrontal cortex. Nat Commun. 2018 09 17; 9(1):3790. PMID: 30224705.
      View in: PubMed
    4. Constantinidis C, Funahashi S, Lee D, Murray JD, Qi XL, Wang M, Arnsten AFT. Persistent Spiking Activity Underlies Working Memory. J Neurosci. 2018 Aug 08; 38(32):7020-7028. PMID: 30089641.
      View in: PubMed
    5. Constantinidis C, Qi XL. Representation of Spatial and Feature Information in the Monkey Dorsal and Ventral Prefrontal Cortex. Front Integr Neurosci. 2018; 12:31. PMID: 30131679.
      View in: PubMed
    6. Liu R, Crawford J, Callahan PM, Terry AV, Constantinidis C, Blake DT. Intermittent stimulation in the nucleus basalis of meynert improves sustained attention in rhesus monkeys. Neuropharmacology. 2018 07 15; 137:202-210. PMID: 29704983.
      View in: PubMed
    7. Blake DT, Terry AV, Plagenhoef M, Constantinidis C, Liu R. Potential for intermittent stimulation of nucleus basalis of Meynert to impact treatment of alzheimer's disease. Commun Integr Biol. 2017; 10(5-6):e1389359. PMID: 29260798.
      View in: PubMed
    8. Tang H, Riley MR, Constantinidis C. Lateralization of Executive Function: Working Memory Advantage for Same Hemifield Stimuli in the Monkey. Front Neurosci. 2017; 11:532. PMID: 29018321.
      View in: PubMed
    9. Liu R, Crawford J, Callahan PM, Terry AV, Constantinidis C, Blake DT. Intermittent Stimulation of the Nucleus Basalis of Meynert Improves Working Memory in Adult Monkeys. Curr Biol. 2017 Sep 11; 27(17):2640-2646.e4. PMID: 28823679.
      View in: PubMed
    10. Riley MR, Qi XL, Constantinidis C. Functional specialization of areas along the anterior-posterior axis of the primate prefrontal cortex. Cereb Cortex. 2017 07 01; 27(7):3683-3697. PMID: 27371761.
      View in: PubMed
    11. Zhou X, Constantinidis C. Fixation target representation in prefrontal cortex during the antisaccade task. J Neurophysiol. 2017 06 01; 117(6):2152-2162. PMID: 28228585.
      View in: PubMed
    12. Murray JD, Bernacchia A, Roy NA, Constantinidis C, Romo R, Wang XJ. Stable population coding for working memory coexists with heterogeneous neural dynamics in prefrontal cortex. Proc Natl Acad Sci U S A. 2017 01 10; 114(2):394-399. PMID: 28028221.
      View in: PubMed
    13. Zhou X, Zhu D, Qi XL, Li S, King SG, Salinas E, Stanford TR, Constantinidis C. Neural correlates of working memory development in adolescent primates. Nat Commun. 2016 11 09; 7:13423. PMID: 27827365.
      View in: PubMed
    14. Constantinidis C, Klingberg T. The neuroscience of working memory capacity and training. Nat Rev Neurosci. 2016 07; 17(7):438-49. PMID: 27225070.
      View in: PubMed
    15. Kobak D, Brendel W, Constantinidis C, Feierstein CE, Kepecs A, Mainen ZF, Qi XL, Romo R, Uchida N, Machens CK. Demixed principal component analysis of neural population data. Elife. 2016 04 12; 5. PMID: 27067378.
      View in: PubMed
    16. Zhou X, Qi XL, Constantinidis C. Distinct Roles of the Prefrontal and Posterior Parietal Cortices in Response Inhibition. Cell Rep. 2016 Mar 29; 14(12):2765-73. PMID: 26997283.
      View in: PubMed
    17. Zhou X, Zhu D, King SG, Lees CJ, Bennett AJ, Salinas E, Stanford TR, Constantinidis C. Behavioral response inhibition and maturation of goal representation in prefrontal cortex after puberty. Proc Natl Acad Sci U S A. 2016 Mar 22; 113(12):3353-8. PMID: 26951656.
      View in: PubMed
    18. Constantinidis C. A Code for Cross-Modal Working Memory. Neuron. 2016 Jan 06; 89(1):3-5. PMID: 26748084.
      View in: PubMed
    19. Riley MR, Constantinidis C. Role of Prefrontal Persistent Activity in Working Memory. Front Syst Neurosci. 2015; 9:181. PMID: 26778980.
      View in: PubMed
    20. Qi XL, Constantinidis C. Lower neuronal variability in the monkey dorsolateral prefrontal than posterior parietal cortex. J Neurophysiol. 2015 Oct; 114(4):2194-203. PMID: 26269556.
      View in: PubMed
    21. Qi XL, Elworthy AC, Lambert BC, Constantinidis C. Representation of remembered stimuli and task information in the monkey dorsolateral prefrontal and posterior parietal cortex. J Neurophysiol. 2015 Jan 01; 113(1):44-57. PMID: 25298389.
      View in: PubMed
    22. Katsuki F, Saito M, Constantinidis C. Influence of monkey dorsolateral prefrontal and posterior parietal activity on behavioral choice during attention tasks. Eur J Neurosci. 2014 Sep; 40(6):2910-21. PMID: 24964224.
      View in: PubMed
    23. Zhou X, Zhu D, Katsuki F, Qi XL, Lees CJ, Bennett AJ, Salinas E, Stanford TR, Constantinidis C. Age-dependent changes in prefrontal intrinsic connectivity. Proc Natl Acad Sci U S A. 2014 Mar 11; 111(10):3853-8. PMID: 24567390.
      View in: PubMed
    24. Wimmer K, Nykamp DQ, Constantinidis C, Compte A. Bump attractor dynamics in prefrontal cortex explains behavioral precision in spatial working memory. Nat Neurosci. 2014 Mar; 17(3):431-9. PMID: 24487232.
      View in: PubMed
    25. Katsuki F, Constantinidis C. Bottom-up and top-down attention: different processes and overlapping neural systems. Neuroscientist. 2014 Oct; 20(5):509-21. PMID: 24362813.
      View in: PubMed
    26. Katsuki F, Constantinidis C. Time course of functional connectivity in primate dorsolateral prefrontal and posterior parietal cortex during working memory. PLoS One. 2013; 8(11):e81601. PMID: 24260582.
      View in: PubMed
    27. Zhou X, Zhu D, Qi XL, Lees CJ, Bennett AJ, Salinas E, Stanford TR, Constantinidis C. Working memory performance and neural activity in prefrontal cortex of peripubertal monkeys. J Neurophysiol. 2013 Dec; 110(11):2648-60. PMID: 24047904.
      View in: PubMed
    28. Constantinidis C, Bucci DJ, Rugg MD. Cognitive functions of the posterior parietal cortex. Front Integr Neurosci. 2013; 7:35. PMID: 23675328.
      View in: PubMed
    29. Katsuki F, Qi XL, Meyer T, Kostelic PM, Salinas E, Constantinidis C. Differences in intrinsic functional organization between dorsolateral prefrontal and posterior parietal cortex. Cereb Cortex. 2014 Sep; 24(9):2334-49. PMID: 23547137.
      View in: PubMed
    30. Qi XL, Constantinidis C. Neural changes after training to perform cognitive tasks. Behav Brain Res. 2013 Mar 15; 241:235-43. PMID: 23261872.
      View in: PubMed
    31. Qi XL, Constantinidis C. Correlated discharges in the primate prefrontal cortex before and after working memory training. Eur J Neurosci. 2012 Dec; 36(11):3538-48. PMID: 22934919.
      View in: PubMed
    32. Qi XL, Constantinidis C. Variability of prefrontal neuronal discharges before and after training in a working memory task. PLoS One. 2012; 7(7):e41053. PMID: 22848426.
      View in: PubMed
    33. Katsuki F, Constantinidis C. Early involvement of prefrontal cortex in visual bottom-up attention. Nat Neurosci. 2012 Jul 22; 15(8):1160-6. PMID: 22820465.
      View in: PubMed
    34. Katsuki F, Constantinidis C. Unique and shared roles of the posterior parietal and dorsolateral prefrontal cortex in cognitive functions. Front Integr Neurosci. 2012; 6:17. PMID: 22563310.
      View in: PubMed
    35. Qi XL, Meyer T, Stanford TR, Constantinidis C. Neural correlates of a decision variable before learning to perform a match/non-match task. J Neurosci. 2012 May 02; 32(18):6161-9. PMID: 22553022.
      View in: PubMed
    36. Zhou X, Katsuki F, Qi XL, Constantinidis C. Neurons with inverted tuning during the delay periods of working memory tasks in the dorsal prefrontal and posterior parietal cortex. J Neurophysiol. 2012 Jul; 108(1):31-8. PMID: 22490554.
      View in: PubMed
    37. Meyers EM, Qi XL, Constantinidis C. Incorporation of new information into prefrontal cortical activity after learning working memory tasks. Proc Natl Acad Sci U S A. 2012 Mar 20; 109(12):4651-6. PMID: 22392988.
      View in: PubMed
    38. Zhou X, Qi XL, Douglas K, Palaninathan K, Kang HS, Buccafusco JJ, Blake DT, Constantinidis C. Cholinergic modulation of working memory activity in primate prefrontal cortex. J Neurophysiol. 2011 Nov; 106(5):2180-8. PMID: 21795623.
      View in: PubMed
    39. Qi XL, Meyer T, Stanford TR, Constantinidis C. Changes in prefrontal neuronal activity after learning to perform a spatial working memory task. Cereb Cortex. 2011 Dec; 21(12):2722-32. PMID: 21527786.
      View in: PubMed
    40. Meyer T, Qi XL, Stanford TR, Constantinidis C. Stimulus selectivity in dorsal and ventral prefrontal cortex after training in working memory tasks. J Neurosci. 2011 Apr 27; 31(17):6266-76. PMID: 21525266.
      View in: PubMed
    41. Qi XL, Katsuki F, Meyer T, Rawley JB, Zhou X, Douglas KL, Constantinidis C. Comparison of neural activity related to working memory in primate dorsolateral prefrontal and posterior parietal cortex. Front Syst Neurosci. 2010; 4:12. PMID: 20514341.
      View in: PubMed
    42. Stein BE, Burr D, Constantinidis C, Laurienti PJ, Alex Meredith M, Perrault TJ, Ramachandran R, Röder B, Rowland BA, Sathian K, Schroeder CE, Shams L, Stanford TR, Wallace MT, Yu L, Lewkowicz DJ. Semantic confusion regarding the development of multisensory integration: a practical solution. Eur J Neurosci. 2010 May; 31(10):1713-20. PMID: 20584174.
      View in: PubMed
    43. Rawley JB, Constantinidis C. Effects of task and coordinate frame of attention in area 7a of the primate posterior parietal cortex. J Vis. 2010 Jan 27; 10(1):12.1-16. PMID: 20143905.
      View in: PubMed
    44. Rawley JB, Constantinidis C. Neural correlates of learning and working memory in the primate posterior parietal cortex. Neurobiol Learn Mem. 2009 Feb; 91(2):129-38. PMID: 19116173.
      View in: PubMed
    45. Burkhardt JM, Constantinidis C, Anstrom KK, Roberts DC, Woodward DJ. Synchronous oscillations and phase reorganization in the basal ganglia during akinesia induced by high-dose haloperidol. Eur J Neurosci. 2007 Oct; 26(7):1912-24. PMID: 17897397.
      View in: PubMed
    46. Meyer T, Qi XL, Constantinidis C. Persistent discharges in the prefrontal cortex of monkeys naive to working memory tasks. Cereb Cortex. 2007 Sep; 17 Suppl 1:i70-6. PMID: 17726005.
      View in: PubMed
    47. Joelving FC, Compte A, Constantinidis C. Temporal properties of posterior parietal neuron discharges during working memory and passive viewing. J Neurophysiol. 2007 Mar; 97(3):2254-66. PMID: 17202244.
      View in: PubMed
    48. Constantinidis C. Posterior parietal mechanisms of visual attention. Rev Neurosci. 2006; 17(4):415-27. PMID: 17139842.
      View in: PubMed
    49. Meyer T, Constantinidis C. A software solution for the control of visual behavioral experimentation. J Neurosci Methods. 2005 Mar 15; 142(1):27-34. PMID: 15652614.
      View in: PubMed
    50. Constantinidis C, Steinmetz MA. Posterior parietal cortex automatically encodes the location of salient stimuli. J Neurosci. 2005 Jan 05; 25(1):233-8. PMID: 15634786.
      View in: PubMed
    51. Constantinidis C, Procyk E. The primate working memory networks. Cogn Affect Behav Neurosci. 2004 Dec; 4(4):444-65. PMID: 15849890.
      View in: PubMed
    52. Constantinidis C, Wang XJ. A neural circuit basis for spatial working memory. Neuroscientist. 2004 Dec; 10(6):553-65. PMID: 15534040.
      View in: PubMed
    53. Wang XJ, Tegnér J, Constantinidis C, Goldman-Rakic PS. Division of labor among distinct subtypes of inhibitory neurons in a cortical microcircuit of working memory. Proc Natl Acad Sci U S A. 2004 Feb 03; 101(5):1368-73. PMID: 14742867.
      View in: PubMed
    54. Compte A, Constantinidis C, Tegner J, Raghavachari S, Chafee MV, Goldman-Rakic PS, Wang XJ. Temporally irregular mnemonic persistent activity in prefrontal neurons of monkeys during a delayed response task. J Neurophysiol. 2003 Nov; 90(5):3441-54. PMID: 12773500.
      View in: PubMed
    55. Constantinidis C, Goldman-Rakic PS. Correlated discharges among putative pyramidal neurons and interneurons in the primate prefrontal cortex. J Neurophysiol. 2002 Dec; 88(6):3487-97. PMID: 12466463.
      View in: PubMed
    56. Constantinidis C, Williams GV, Goldman-Rakic PS. A role for inhibition in shaping the temporal flow of information in prefrontal cortex. Nat Neurosci. 2002 Feb; 5(2):175-80. PMID: 11802172.
      View in: PubMed
    57. Constantinidis C, Steinmetz MA. Neuronal responses in area 7a to multiple-stimulus displays: I. neurons encode the location of the salient stimulus. Cereb Cortex. 2001 Jul; 11(7):581-91. PMID: 11415960.
      View in: PubMed
    58. Constantinidis C, Steinmetz MA. Neuronal responses in area 7a to multiple stimulus displays: II. responses are suppressed at the cued location. Cereb Cortex. 2001 Jul; 11(7):592-7. PMID: 11415961.
      View in: PubMed
    59. Constantinidis C, Franowicz MN, Goldman-Rakic PS. Coding specificity in cortical microcircuits: a multiple-electrode analysis of primate prefrontal cortex. J Neurosci. 2001 May 15; 21(10):3646-55. PMID: 11331394.
      View in: PubMed
    60. Constantinidis C, Franowicz MN, Goldman-Rakic PS. The sensory nature of mnemonic representation in the primate prefrontal cortex. Nat Neurosci. 2001 Mar; 4(3):311-6. PMID: 11224549.
      View in: PubMed
    61. Constantinidis C, Steinmetz MA. Neuronal activity in posterior parietal area 7a during the delay periods of a spatial memory task. J Neurophysiol. 1996 Aug; 76(2):1352-5. PMID: 8871242.
      View in: PubMed
    62. Steinmetz MA, Constantinidis C. Neurophysiological evidence for a role of posterior parietal cortex in redirecting visual attention. Cereb Cortex. 1995 Sep-Oct; 5(5):448-56. PMID: 8547791.
      View in: PubMed
    63. Steinmetz MA, Connor CE, Constantinidis C, McLaughlin JR. Covert attention suppresses neuronal responses in area 7a of the posterior parietal cortex. J Neurophysiol. 1994 Aug; 72(2):1020-3. PMID: 7983507.
      View in: PubMed
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