Defects in the SEX DETERMINATION PROCESS in 46, XY individuals that result in abnormal gonadal development and deficiencies in TESTOSTERONE and subsequently ANTIMULLERIAN HORMONE or other factors required for normal male sex development. This leads to the development of female phenotypes (male to female sex reversal), normal to tall stature, and bilateral streak or dysgenic gonads which are susceptible to GONADAL TISSUE NEOPLASMS. An XY gonadal dysgenesis is associated with structural abnormalities on the Y CHROMOSOME, a mutation in the GENE, SRY, or a mutation in other autosomal genes that are involved in sex determination.

Descriptor ID	D006061
MeSH Number(s)	C12.706.316.096.687 C12.706.316.309.388 C13.351.875.253.096.687 C13.351.875.253.309.388 C16.131.939.316.096.687 C16.131.939.316.309.388 C19.391.119.096.687 C19.391.119.309.388
Concept/Terms	Gonadal Dysgenesis, 46,XY Gonadal Dysgenesis, 46,XY Sex Reversal, Gonadal, 46, XY Gonadal Dysgenesis, 46, XY 46, XY Gonadal Dysgenesis 46, XY Gonadal Sex Reversal Swyer Syndrome Swyer Syndrome Syndrome, Swyer Pure Gonadal Dysgenesis, 46, XY Complete Gonadal Dysgenesis, 46, XY

Below are MeSH descriptors whose meaning is more general than "Gonadal Dysgenesis, 46,XY".

Below are MeSH descriptors whose meaning is related to "Gonadal Dysgenesis, 46,XY".

Below are MeSH descriptors whose meaning is more specific than "Gonadal Dysgenesis, 46,XY".