Multiple Endocrine Neoplasia Type 1
"Multiple Endocrine Neoplasia Type 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A form of multiple endocrine neoplasia that is characterized by the combined occurrence of tumors in the PARATHYROID GLANDS, the PITUITARY GLAND, and the PANCREATIC ISLETS. The resulting clinical signs include HYPERPARATHYROIDISM; HYPERCALCEMIA; HYPERPROLACTINEMIA; CUSHING DISEASE; GASTRINOMA; and ZOLLINGER-ELLISON SYNDROME. This disease is due to loss-of-function of the MEN1 gene, a tumor suppressor gene (GENES, TUMOR SUPPRESSOR) on CHROMOSOME 11 (Locus: 11q13).
Descriptor ID |
D018761
|
MeSH Number(s) |
C04.588.322.400.500 C04.651.600.500 C04.700.630.500 C16.320.700.630.500 C19.344.400.500
|
Concept/Terms |
Multiple Endocrine Neoplasia Type 1- Multiple Endocrine Neoplasia Type 1
- MEN I
- Wermer Syndrome
- Neoplasia, Multiple Endocrine Type 1
- MEN1
- Neoplasms, Multiple Endocrine Type 1
- MEN 1
- MEA 1
- Multiple Endocrine Neoplasia Type I
- Neoplasms, Multiple Endocrine Type I
- MEA I
- Multiple Endocrine Neoplasms Type 1
|
Below are MeSH descriptors whose meaning is more general than "Multiple Endocrine Neoplasia Type 1".
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