Cyclin-Dependent Kinase Inhibitor p16
"Cyclin-Dependent Kinase Inhibitor p16" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A product of the p16 tumor suppressor gene (GENES, P16). It is also called INK4 or INK4A because it is the prototype member of the INK4 CYCLIN-DEPENDENT KINASE INHIBITORS. This protein is produced from the alpha mRNA transcript of the p16 gene. The other gene product, produced from the alternatively spliced beta transcript, is TUMOR SUPPRESSOR PROTEIN P14ARF. Both p16 gene products have tumor suppressor functions.
Descriptor ID |
D019941
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MeSH Number(s) |
D12.644.360.225.200 D12.776.167.187.200 D12.776.476.225.200 D12.776.624.776.355.200
|
Concept/Terms |
Cyclin-Dependent Kinase Inhibitor p16- Cyclin-Dependent Kinase Inhibitor p16
- Cyclin Dependent Kinase Inhibitor p16
- CDKN2 Protein
- CDKN2A Protein
- Cyclin-Dependent Kinase Inhibitor-2A
- Cyclin Dependent Kinase Inhibitor 2A
- p16INK4A Protein
- MTS1 Protein
- Multiple Tumor Suppressor-1
- Multiple Tumor Suppressor 1
- p16(INK4A)
- p16INK4 Protein
- Cdk4-Associated Protein p16
- Cdk4 Associated Protein p16
- INK4A Protein
- Protein, INK4A
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Below are MeSH descriptors whose meaning is more general than "Cyclin-Dependent Kinase Inhibitor p16".
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Year | Major Topic | Minor Topic | Total |
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1998 | 1 | 0 | 1 |
2004 | 0 | 1 | 1 |
2005 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
2007 | 1 | 0 | 1 |
2008 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2012 | 0 | 2 | 2 |
2013 | 0 | 1 | 1 |
2014 | 1 | 0 | 1 |
2016 | 1 | 1 | 2 |
2018 | 2 | 1 | 3 |
2022 | 0 | 1 | 1 |
2023 | 0 | 1 | 1 |
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