Compounds that specifically inhibit the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. These agents have been used in treatment of depression, panic disorder, obsessive-compulsive behavior, and alcoholism, as analgesics, and to treat obesity and bulimia. Many of the ADRENERGIC UPTAKE INHIBITORS also inhibit serotonin uptake; they are not included here.

Descriptor ID	D017367
MeSH Number(s)	D27.505.519.625.600.850 D27.505.519.625.850.900 D27.505.696.577.600.850 D27.505.696.577.850.900
Concept/Terms	Serotonin Uptake Inhibitors Serotonin Uptake Inhibitors 5-Hydroxytryptamine Uptake Inhibitors 5 Hydroxytryptamine Uptake Inhibitors Inhibitors, 5-HT Uptake Inhibitors, 5 HT Uptake Inhibitors, 5-Hydroxytryptamine Uptake Inhibitors, 5 Hydroxytryptamine Uptake Uptake Inhibitors, Serotonin Inhibitors, Serotonin Uptake Reuptake Inhibitors, Serotonin Serotonin Reuptake Inhibitors Uptake Inhibitors, 5-HT Uptake Inhibitors, 5 HT Uptake Inhibitors, 5-Hydroxytryptamine Uptake Inhibitors, 5 Hydroxytryptamine 5-HT Uptake Inhibitors 5 HT Uptake Inhibitors Inhibitors, Serotonin Reuptake Selective Serotonin Reuptake Inhibitors Selective Serotonin Reuptake Inhibitors

Below are MeSH descriptors whose meaning is more general than "Serotonin Uptake Inhibitors".

Below are MeSH descriptors whose meaning is related to "Serotonin Uptake Inhibitors".

Below are MeSH descriptors whose meaning is more specific than "Serotonin Uptake Inhibitors".