Anti-inflammatory agents that are not steroids. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They are used primarily in the treatment of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. Certain NSAIDs also may inhibit lipoxygenase enzymes or TYPE C PHOSPHOLIPASES or may modulate T-cell function. (AMA Drug Evaluations Annual, 1994, p 1814-5)

Descriptor ID	D000894
MeSH Number(s)	D27.505.696.663.850.014.040.500 D27.505.954.158.030 D27.505.954.329.030
Concept/Terms	Anti-Inflammatory Agents, Non-Steroidal Anti-Inflammatory Agents, Non-Steroidal Anti Inflammatory Agents, Non Steroidal Anti Inflammatory Agents, Nonsteroidal NSAIDs Antiinflammatory Agents, Non Steroidal Antiinflammatory Agents, Nonsteroidal Agents, Nonsteroidal Antiinflammatory Nonsteroidal Antiinflammatory Agents Non-Steroidal Anti-Inflammatory Agents Agents, Non-Steroidal Anti-Inflammatory Non Steroidal Anti Inflammatory Agents Nonsteroidal Anti-Inflammatory Agents Agents, Nonsteroidal Anti-Inflammatory Anti-Inflammatory Agents, Nonsteroidal Nonsteroidal Anti Inflammatory Agents Anti-Rheumatic Agents, Non-Steroidal Anti-Rheumatic Agents, Non-Steroidal Agents, Non-Steroidal Anti-Rheumatic Anti Rheumatic Agents, Non Steroidal Non-Steroidal Anti-Rheumatic Agents Antirheumatic Agents, Non-Steroidal Agents, Non-Steroidal Antirheumatic Antirheumatic Agents, Non Steroidal Non-Steroidal Antirheumatic Agents Aspirin-Like Agents Aspirin-Like Agents Agents, Aspirin-Like Aspirin Like Agents Analgesics, Anti-Inflammatory Analgesics, Anti-Inflammatory Analgesics, Anti Inflammatory Anti-Inflammatory Analgesics

Below are MeSH descriptors whose meaning is more general than "Anti-Inflammatory Agents, Non-Steroidal".

Below are MeSH descriptors whose meaning is related to "Anti-Inflammatory Agents, Non-Steroidal".

Below are MeSH descriptors whose meaning is more specific than "Anti-Inflammatory Agents, Non-Steroidal".