A rare, slowly progressive encephalitis caused by chronic infection with the MEASLES VIRUS. The condition occurs primarily in children and young adults, approximately 2-8 years after the initial infection. A gradual decline in intellectual abilities and behavioral alterations are followed by progressive MYOCLONUS; MUSCLE SPASTICITY; SEIZURES; DEMENTIA; autonomic dysfunction; and ATAXIA. DEATH usually occurs 1-3 years after disease onset. Pathologic features include perivascular cuffing, eosinophilic cytoplasmic inclusions, neurophagia, and fibrous gliosis. It is caused by the SSPE virus, which is a defective variant of MEASLES VIRUS. (From Adams et al., Principles of Neurology, 6th ed, pp767-8)

Descriptor ID	D013344
MeSH Number(s)	C02.182.500.300.600 C02.290.700 C02.782.580.600.500.500.800 C02.839.862 C10.228.228.210.150.300.600 C10.228.228.245.340.700
Concept/Terms	Subacute Sclerosing Panencephalitis Subacute Sclerosing Panencephalitis Sclerosing Panencephalitis, Subacute Panencephalitides, Subacute Sclerosing Sclerosing Panencephalitides, Subacute Subacute Sclerosing Panencephalitides Panencephalitis, Subacute Sclerosing Leukoencephalitis, Van Bogaert's Leukoencephalitis, Van Bogaert Leukoencephalitis, Van Bogaerts Inclusion Body Encephalitis, Measles Sclerosing Leukoencephalitis, Subacute Leukoencephalitides, Subacute Sclerosing Sclerosing Leukoencephalitides, Subacute Subacute Sclerosing Leukoencephalitides Subacute Sclerosing Leukoencephalitis Leukoencephalitis, Subacute Sclerosing Measles Inclusion Body Encephalitis Encephaltis, Inclusion Body, Measles SSPE Van Bogaert's Leukoencephalitis Van Bogaert Leukoencephalitis Van Bogaerts Leukoencephalitis

Below are MeSH descriptors whose meaning is more general than "Subacute Sclerosing Panencephalitis".

Below are MeSH descriptors whose meaning is related to "Subacute Sclerosing Panencephalitis".

Below are MeSH descriptors whose meaning is more specific than "Subacute Sclerosing Panencephalitis".