"Mice, Inbred MRL lpr" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mouse substrain that is genetically predisposed to the development of systemic lupus erythematosus-like syndrome, which has been found to be clinically similar to the human disease. It has been determined that this mouse strain carries a mutation in the fas gene. Also, the MRL/lpr is a useful model to study behavioral and cognitive deficits found in autoimmune diseases and the efficacy of immunosuppressive agents.
| Descriptor ID |
D019463
|
| MeSH Number(s) |
B01.050.050.157.520.555 B01.050.050.199.520.520.555 B01.050.150.900.649.865.635.505.500.400.555
|
| Concept/Terms |
Mice, Inbred MRL lpr- Mice, Inbred MRL lpr
- Mice, MRL lpr
- MRL lpr Mice
- lpr Mice, MRL
- Mouse, MRL lpr
- MRL lpr Mouse
- lpr Mouse, MRL
- Mouse, Inbred MRL lpr
|
Below are MeSH descriptors whose meaning is more general than "Mice, Inbred MRL lpr".
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mice, Inbred MRL lpr" by people in Profiles.