"Complement C1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The first complement component to act in the activation of CLASSICAL COMPLEMENT PATHWAY. It is a calcium-dependent trimolecular complex made up of three subcomponents: COMPLEMENT C1Q; COMPLEMENT C1R; and COMPLEMENT C1S at 1:2:2 ratios. When the intact C1 binds to at least two antibodies (involving C1q), C1r and C1s are sequentially activated, leading to subsequent steps in the cascade of COMPLEMENT ACTIVATION.
| Descriptor ID |
D003172
|
| MeSH Number(s) |
D12.776.124.486.274.050
|
| Concept/Terms |
Complement C1- Complement C1
- C1, Complement
- Complement 1
- C1 Complement
- Complement, C1
- Complement Component 1
- Component 1, Complement
|
Below are MeSH descriptors whose meaning is more general than "Complement C1".
Below are MeSH descriptors whose meaning is more specific than "Complement C1".
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Below are the most recent publications written about "Complement C1" by people in Profiles.