"Cocaine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.
| Descriptor ID |
D003042
|
| MeSH Number(s) |
D02.145.074.722.388 D03.132.889.354 D03.605.869.388 D04.075.080.875.099.722.388
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cocaine".
Below are MeSH descriptors whose meaning is more specific than "Cocaine".
This graph shows the total number of publications written about "Cocaine" by people in this website by year, and whether "Cocaine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 2 | 0 | 2 |
| 1998 | 1 | 2 | 3 |
| 2000 | 2 | 3 | 5 |
| 2002 | 7 | 0 | 7 |
| 2003 | 9 | 0 | 9 |
| 2004 | 9 | 3 | 12 |
| 2005 | 8 | 1 | 9 |
| 2006 | 8 | 1 | 9 |
| 2007 | 8 | 1 | 9 |
| 2008 | 8 | 2 | 10 |
| 2009 | 4 | 1 | 5 |
| 2010 | 8 | 1 | 9 |
| 2011 | 6 | 1 | 7 |
| 2012 | 8 | 7 | 15 |
| 2013 | 7 | 2 | 9 |
| 2014 | 7 | 4 | 11 |
| 2015 | 10 | 3 | 13 |
| 2016 | 12 | 2 | 14 |
| 2017 | 5 | 0 | 5 |
| 2018 | 1 | 0 | 1 |
| 2019 | 4 | 0 | 4 |
| 2020 | 5 | 0 | 5 |
| 2022 | 4 | 0 | 4 |
| 2023 | 3 | 0 | 3 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cocaine" by people in Profiles.