Recirculating, dendritic, antigen-presenting cells containing characteristic racket-shaped granules (Birbeck granules). They are found principally in the stratum spinosum of the EPIDERMIS and are rich in Class II MAJOR HISTOCOMPATIBILITY COMPLEX molecules. Langerhans cells were the first dendritic cell to be described and have been a model of study for other dendritic cells (DCs), especially other migrating DCs such as dermal DCs and INTERSTITIAL DENDRITIC CELLS.

Descriptor ID	D007801
MeSH Number(s)	A11.066.270.500 A11.436.270.545 A15.382.066.270.500 A15.382.812.260.500
Concept/Terms	Langerhans Cells Langerhans Cells Cells, Langerhans Epidermal Dendritic Cells Dendritic Cells, Epidermal Cell, Epidermal Dendritic Cells, Epidermal Dendritic Dendritic Cell, Epidermal Epidermal Dendritic Cell Skin Dendritic Cells Skin Dendritic Cells Cell, Skin Dendritic Cells, Skin Dendritic Dendritic Cell, Skin Skin Dendritic Cell Dendritic Cells, Skin Dermal Dendritic Cells Dermal Dendritic Cells Cell, Dermal Dendritic Cells, Dermal Dendritic Dendritic Cell, Dermal Dermal Dendritic Cell Dendritic Cells, Dermal

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Below are MeSH descriptors whose meaning is more specific than "Langerhans Cells".